Lista de obras - Giorgio Giardina - Dominio Público Uruguay

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

artículo científico publicado en 2015

C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG

artículo científico publicado en 2013

Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target

artículo científico publicado en 2012

Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

artículo científico publicado en 2020

Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR.

artículo científico publicado en 2014

Glucose Metabolism in the Progression of Prostate Cancer

artículo científico publicado en 2017

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

artículo científico publicado en 2015

Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors

artículo científico publicado en 2012

In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD

artículo científico publicado en 2015

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain

artículo científico publicado en 2013

N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells

artículo científico publicado en 2019

N-oxide sensing and denitrification: the DNR transcription factors.

artículo científico publicado en 2006

N-oxide sensing in Pseudomonas aeruginosa: expression and preliminary characterization of DNR, an FNR-CRP type transcriptional regulator.

artículo científico publicado en 2005

NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR

artículo científico publicado en 2008

New Insights Emerging from Recent Investigations on Human Group II Pyridoxal 5'-Phosphate Decarboxylases

artículo científico publicado en 2016

New insights into the activity of Pseudomonas aeruginosa cd1 nitrite reductase

artículo científico publicado en 2008

Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease.

artículo científico

Nitrite reduction: a ubiquitous function from a pre-aerobic past.

artículo científico publicado en 2009

Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis

artículo científico publicado en 2014

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases ⬇️

artículo científico publicado el 5 de diciembre de 2011

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy ⬇️

artículo científico publicado el 28 de enero de 2013

Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis

artículo científico publicado en 2017

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.

artículo científico publicado en 2014

Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.

artículo científico publicado en 2015

Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site

artículo científico publicado en 2015

Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

artículo científico publicado en 2022

Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts

artículo científico publicado en 2021

Synthesis of Triazole-Linked Analogues of c-di-GMP and Their Interactions with Diguanylate Cyclase.

artículo científico publicado en 2015

The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide-sensing mechanisms

artículo científico publicado en 2011

The catalytic mechanism of Pseudomonas aeruginosa cd1 nitrite reductase

artículo científico publicado en 2011

The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli.

artículo científico publicado en 2009

Unusual heme binding properties of the dissimilative nitrate respiration regulator, a bacterial nitric oxide sensor.

artículo científico publicado en 2012

Use of the Pd-PromotedExtended One-Pot (EOP) Synthetic Protocol for the Modular Construction of Poly-(arylene ethynylene)co-Polymers [?Ar?C?C?Ar??C?C?]n, Opto- and Electro-Responsive Materials for Advanced Technology

scholarly article by Alessandra Micozzi et al published January 2005 in Advanced Synthesis & Catalysis

Lista de obras de Giorgio Giardina

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG

Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target

Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR.

Glucose Metabolism in the Progression of Prostate Cancer

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors

In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain

N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells

N-oxide sensing and denitrification: the DNR transcription factors.

N-oxide sensing in Pseudomonas aeruginosa: expression and preliminary characterization of DNR, an FNR-CRP type transcriptional regulator.

NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR

New Insights Emerging from Recent Investigations on Human Group II Pyridoxal 5'-Phosphate Decarboxylases

New insights into the activity of Pseudomonas aeruginosa cd1 nitrite reductase

Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease.

Nitrite reduction: a ubiquitous function from a pre-aerobic past.

Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases ⬇️

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy ⬇️

Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.

Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.

Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site

Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts

Synthesis of Triazole-Linked Analogues of c-di-GMP and Their Interactions with Diguanylate Cyclase.

The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide-sensing mechanisms

The catalytic mechanism of Pseudomonas aeruginosa cd1 nitrite reductase

The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli.

Unusual heme binding properties of the dissimilative nitrate respiration regulator, a bacterial nitric oxide sensor.

Use of the Pd-PromotedExtended One-Pot (EOP) Synthetic Protocol for the Modular Construction of Poly-(arylene ethynylene)co-Polymers [?Ar?C?C?Ar??C?C?]n, Opto- and Electro-Responsive Materials for Advanced Technology

XAS study of the active site of a bacterial heme-sensor