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Lista de obras de Guy Brusselle

A 41-year-old man with breast cancer and dyspnoea: an exceptional complication in an uncommon disease ⬇️

artículo científico publicado el 1 de septiembre de 2010

A prospective, longitudinal study evaluating the baseline six-minute walk test as an individual reference value in systemic sclerosis patients

scientific article published on 01 July 2018

A qualitative interpretation of challenges associated with helping patients with multiple chronic diseases identify their goals.

artículo científico publicado en 2016

AB014. Effect of beta-blockers on the risk of COPD exacerbations.

artículo científico publicado en 2016

AB028. Use of β-blockers and the risk of asthma exacerbations.

artículo científico publicado en 2016

Adherence to the 2015 Dutch dietary guidelines and risk of non-communicable diseases and mortality in the Rotterdam Study

artículo científico publicado en 2017

After asthma: redefining airways diseases.

artículo científico publicado en 2017

Anti-MDA5 positive dermatomyositis complicated with rapidly progressive interstitial lung disease - a case report.

artículo científico publicado en 2017

Are the antimicrobial properties of macrolides required for their therapeutic efficacy in chronic neutrophilic airway diseases?

artículo científico publicado en 2015

Association between blood eosinophil count and risk of readmission for patients with asthma: Historical cohort study

artículo científico publicado en 2018

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of elevated fractional exhaled nitric oxide concentration and blood eosinophil count with severe asthma exacerbations

scientific article published on 21 August 2019

Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD.

artículo científico publicado en 2017

Asthma inflammatory phenotypes show differential microRNA expression in sputum

artículo científico publicado en 2016

Atherosclerotic calcification in major vessel beds in chronic obstructive pulmonary disease: The Rotterdam Study

scientific article published on 24 October 2019

Azithromycin during Acute Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization (BACE). A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial

scientific article published on 01 October 2019

Blood eosinophil level and lung function trajectories: cross-sectional and longitudinal studies in European cohorts

artículo científico publicado en 2020

Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial

scientific article published on 04 July 2019

Bone morphogenetic protein 6 (BMP-6) modulates lung function, pulmonary iron levels and cigarette smoke-induced inflammation

scientific article published on 12 December 2018

COPD is associated with an increased risk of peripheral artery disease and mortality

artículo científico publicado en 2018

COVID-19 and biologics in severe asthma: data from the Belgian Severe Asthma Registry

scientific article published on 22 October 2020

Challenges of COPD diagnosis

artículo científico

Change in blood eosinophils following treatment with inhaled corticosteroids may predict long-term clinical response in COPD

artículo científico publicado en 2020

Chronic Airway Diseases Early Stratification (CADSET): a new ERS Clinical Research Collaboration

scientific article published on 18 March 2019

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut.

artículo científico publicado en 2015

Chronic obstructive pulmonary disease and comorbidities through the eyes of the patient ⬇️

artículo científico publicado el 1 de agosto de 2012

Chronic obstructive pulmonary disease and the development of atrial fibrillation

artículo científico publicado en 2018

Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis

artículo científico publicado en 2014

Core outcome set for the management of acute exacerbations of chronic obstructive pulmonary disease: the COS-AECOPD ERS Task Force study protocol

scientific article published on 01 July 2020

Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

artículo científico publicado en 2017

Cytokine Manipulation in Animal Models of Asthma ⬇️

artículo científico publicado el 1 de octubre de 1997

Cytokines and their receptors as therapeutic targets in asthma

artículo científico publicado el 1 de agosto de 1998

DNA methylation is associated with lung function in never smokers

scientific article published on 02 December 2019

DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients

artículo científico publicado en 2017

Design of a frailty index among community living middle-aged and older people: The Rotterdam study

artículo científico publicado en 2016

Does maintenance azithromycin reduce asthma exacerbations? An individual participant data meta-analysis

artículo científico publicado en 2019

Dysregulated fibulin-5 expression and elastogenesis in COPD lungs: pyromaniac or fire fighter?

artículo científico publicado en 2014

Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses

artículo científico publicado en 2016

ERS Clinical Research Collaborations: underpinning research excellence

scientific article published on 15 September 2018

ERS/EAACI statement on severe exacerbations in asthma in adults: facts, priorities and key research questions

scientific article published on 28 September 2019

Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma: results from two phase 3, randomised, double-blind, pl

artículo científico publicado en 2020

Efficacy of tiotropium-olodaterol fixed-dose combination in COPD

artículo científico publicado en 2016

Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure.

artículo científico publicado en 2017

Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease

artículo científico publicado en 2017

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

artículo científico publicado en 2017

Expanding the spectrum of European Respiratory Society official scientific documents: short documents complement clinical practice guidelines, statements and technical standards

scientific article published on 04 June 2020

Exposing a deadly alliance: Novel insights into the biological links between COPD and lung cancer ⬇️

artículo científico publicado el 21 de mayo de 2013

F ENO as a biomarker guide for inhaled corticosteroid step down in patients with mild-to-moderate well-controlled asthma

scientific article published on 21 May 2020

Frequent exacerbators--a distinct phenotype of severe asthma

artículo científico publicado en 2014

GDF-15 in Pulmonary and Critical Care Medicine

scientific article published on 01 June 2019

GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents

artículo científico publicado en 2019

GINA fosters World Asthma Day 2020 to prevent asthma deaths

artículo científico publicado en 2020

Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure

artículo científico publicado en 2017

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

artículo científico publicado en 2019

Genome-wide association analysis identifies six new loci associated with forced vital capacity

artículo científico publicado en 2014

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

artículo científico publicado en 2011

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

artículo científico publicado en 2012

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

artículo científico publicado en 2012

Hand-held fractional exhaled nitric oxide measurements as a non-invasive indicator of systemic inflammation in Crohn's disease ⬇️

artículo científico publicado el 18 de octubre de 2012

Heritability and genome-wide association study of diffusing capacity of the lung

scientific article published on 15 September 2018

IL ‐33 signalling contributes to pollutant‐induced allergic airway inflammation

artículo científico publicado en 2018

Improving inhaler adherence in patients with chronic obstructive pulmonary disease: a cost-effectiveness analysis

artículo científico publicado en 2014

Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects

scientific article published on 16 July 2020

Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease

artículo científico publicado en 2016

Influence of chronic azithromycin treatment on the composition of the oropharyngeal microbial community in patients with severe asthma

artículo científico publicado en 2017

Inhaled corticosteroids in COPD and onset of type 2 diabetes and osteoporosis: matched cohort study

scientific article published on 28 October 2019

Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155

scientific article published on 04 June 2020

Is there a role for macrolides in severe asthma?

artículo científico

Large Meta-Analysis in the CHARGE Consortium Provides Evidence For an Association of Serum Vitamin D With Pulmonary Function

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

artículo científico publicado en 2014

Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population: A population-based cohort study

scientific article published on 04 February 2019

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population

artículo científico publicado en 2019

Long-acting bronchodilators improve health related quality of life in patients with COPD.

artículo científico publicado en 2013

Long-term Safety and Clinical Benefit of Mepolizumab in Patients With the Most Severe Eosinophilic Asthma: The COSMEX Study

artículo científico publicado en 2019

Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns

artículo científico publicado en 2014

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

artículo científico publicado en 2010

Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function

artículo científico publicado en 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

artículo científico publicado en 2016

Microscopic polyangiitis involving the breast

artículo científico publicado el 1 de marzo de 2011

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

artículo científico publicado en 2015

Moving forward from drug-centred to patient-centred research: A white paper initiated by EORTC and developed together with the BioMed Alliance members

scientific article published on 21 February 2019

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

artículo científico publicado en 2017

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

scientific article published in Nature Communications

Multinational cohort study of mortality in patients with asthma and severe asthma

scientific article published on 02 March 2020

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

artículo científico publicado en 2019

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

artículo científico publicado en 2019

Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence

artículo científico publicado en 2019

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1)

scientific article published on 01 August 2019

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 2)

scientific article published on 01 September 2019

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

artículo científico publicado en 2016

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression

scientific article published on 02 April 2019

Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma

scientific article published on 07 February 2019

Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association

artículo científico publicado en 2019

Organization and chromosomal localization of the human interleukin 5 receptor alpha-chain gene

artículo científico publicado el 1 de septiembre de 1992

Performance of database-derived severe exacerbations and asthma control measures in asthma: responsiveness and predictive utility in a UK primary care database with linked questionnaire data

article

Peripheral Artery Disease in Patients with Chronic Obstructive Pulmonary Disease.

artículo científico publicado en 2017

Personalized medicine with biologics for severe type 2 asthma: current status and future prospects.

artículo científico publicado en 2017

Prevalence and Characteristics of Asthma-Chronic Obstructive Pulmonary Disease Overlap in Routine Primary Care Practices

artículo científico publicado en 2019

Prevalence and burden of asthma in China: time to act

artículo científico publicado en 2019

Prevalence and incidence of, and risk factors for chronic cough in the adult population: the Rotterdam Study

scientific article published on 19 April 2020

Prevalence of Asthma and COPD and Blood Eosinophil Count in a Middle-Aged Belgian Population

artículo científico publicado en 2019

Prevalence of atopy, asthma and COPD in an urban and a rural area of an African country ⬇️

artículo científico publicado el 23 de julio de 2011

Pro- and Anti-Inflammatory Role of ChemR23 Signaling in Pollutant-Induced Inflammatory Lung Responses

artículo científico publicado en 2016

Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population: the Rotterdam Study

artículo científico publicado en 2017

Pulmonary function and diffusion capacity are associated with pulmonary arterial systolic pressure in the general population: The Rotterdam Study

artículo científico publicado en 2017

Quality standards in respiratory real-life effectiveness research: the REal Life EVidence AssessmeNt Tool (RELEVANT): report from the Respiratory Effectiveness Group-European Academy of Allergy and Clinical Immunology Task Force

artículo científico publicado en 2019

Real-life effectiveness of omalizumab in difficult-to-treat versus severe asthma: a national cohort study in Belgium

artículo científico publicado en 2019

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

artículo científico publicado en 2019

Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.

artículo científico publicado en 2017

Reply: Direct Detection of Circulating MicroRNAs Unveiled the Absence of MicroRNA-218-5p in Smoker Subjects.

artículo científico publicado en 2017

Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials

artículo científico publicado en 2015

Reslizumab in Eosinophilic Asthma: A Review

artículo científico publicado en 2017

Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils

artículo científico publicado en 2017

Risk of a biased assessment of the evidence when limiting literature searches to the English language: macrolides in asthma as an illustrative example

artículo científico publicado en 2014

Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD.

artículo científico

Safety of reslizumab in uncontrolled asthma with eosinophilia: a pooled analysis from six trials.

artículo científico publicado en 2019

Sarcopenia in COPD: a systematic review and meta-analysis

scientific article published on 13 November 2019

Severe eosinophilic asthma with nasal polyposis: A phenotype for improved sinonasal and asthma outcomes with mepolizumab therapy

artículo científico publicado en 2020

Sex-Specific Genetic Risk Factors for Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2017

Simultaneous inhibition of thymic stromal lymphopoietin, IL-33 and IL-25: A therapeutic option in asthma?

scientific article published on 25 November 2019

Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma

artículo científico publicado en 2014

Susceptibility to chronic mucus hypersecretion, a genome wide association study

artículo científico publicado en 2014

Targeted Therapy for Older Patients with Uncontrolled Severe Asthma: Current and Future Prospects

artículo científico publicado en 2016

The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial

artículo científico publicado en 2016

The ERS fellowship portfolio: fostering excellence and diversity

artículo científico publicado en 2019

The European Respiratory Society evaluates its 2013-2018 strategic plan implementation

artículo científico publicado en 2016

The European Respiratory Society's 10 Principles for Lung Health

artículo científico publicado en 2018

The European Respiratory Society: ensuring excellence through education best practice

scientific article published on 15 September 2018

The REal Life EVidence AssessmeNt Tool (RELEVANT): development of a novel quality assurance asset to rate observational comparative effectiveness research studies

scientific article published on 27 March 2019

The Rotterdam Study: 2016 objectives and design update

artículo científico publicado en 2015

The association between dietary protein intake, energy intake and physical frailty: results from the Rotterdam Study

scientific article published on 13 November 2018

The effects of lutein on respiratory health across the life course: A systematic review

artículo científico publicado en 2016

The impact of the prostaglandin D2 receptor 2 and its downstream effects on the pathophysiology of asthma

scientific article published on 29 July 2019

The interrelatedness of chronic cough and chronic pain

artículo científico publicado en 2020

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD: current evidence and future prospects

artículo científico publicado en 2019

The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD

scientific article published on 09 December 2019

Tiotropium Handihaler and the risk of cardio- or cerebrovascular events and mortality in patients with COPD ⬇️

artículo científico publicado el 21 de octubre de 2011

Toward effective prescription of inhaled corticosteroids in chronic airway disease

scientific article published on 18 October 2018

Trajectory and mortality of preserved ratio impaired spirometry: the Rotterdam Study

artículo científico publicado en 2020

Tralokinumab did not demonstrate oral corticosteroid-sparing effects in severe asthma

artículo científico publicado en 2019

Update on immunogenicity in severe asthma: Experience with mepolizumab

scientific article published on 05 April 2019

Urgent need for pragmatic trial platforms in severe asthma

scientific article published on 01 August 2018

Using a bronchial airway gene expression classifier

artículo científico publicado en 2016

Validation of Clinical COPD Phenotypes for Prognosis of Long-Term Mortality in Swedish and Dutch Cohorts

artículo científico publicado en 2022

Variability in total serum IgE over 1 year in severe asthmatics

scientific article published on 29 March 2019

Vilanterol fluticasone and mortality in comorbid COPD GOLD B.

artículo científico publicado en 2016

Why doesn't reducing exacerbations decrease COPD mortality?

artículo científico publicado en 2014

[Effectiveness of pharmaceutical care for patients with COPD: translated review of the recently published PHARMACOP trial]

scientific article published on 01 September 2014

[Optimizing pharmacotherapy in patients with COPD by community-pharmacists: a cost-effectiveness analysis]

scientific article published on 01 September 2014

microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach.

artículo científico publicado en 2017

β2-Adrenergic Receptor (ADRB2) Gene Polymorphisms and Risk of COPD Exacerbations: The Rotterdam Study

artículo científico publicado en 2019

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