Lista de obras - Ronald N. Hines - Dominio Público Uruguay

A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing

article

A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia

artículo científico publicado en 2011

A Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes

scientific article published on 29 July 2019

A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake

artículo científico publicado en 1998

A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities

artículo científico publicado en 1994

Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.

artículo científico publicado en 2016

Altered regulation of the cytochrome P4501A1 gene: novel inducer-independent gene expression in pulmonary carcinoma cell lines

artículo científico publicado en 1989

Application of epigenetic data in human health risk assessment

artículo científico publicado en 2017

Approaches for assessing risks to sensitive populations: lessons learned from evaluating risks in the pediatric population

artículo científico publicado en 2010

Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression

artículo científico publicado en 2015

Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.

artículo científico publicado en 2003

Demonstration of microsomal oxygenation of the benzo ring of 6-nitrobenzo[a]pyrene by thin-layer chromatography

scientific article published on 01 May 1984

Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

artículo científico

Developmental Expression of the Cytosolic Sulfotransferases in Human Liver.

artículo científico publicado en 2019

Developmental expression of drug metabolizing enzymes: impact on disposition in neonates and young children.

artículo científico

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver

artículo científico publicado en 2016

Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.

artículo científico publicado en 2005

Functional characterization of the human CYP1A1 negative regulatory element: modulation of Ah receptor mediated transcriptional activity ⬇️

artículo científico publicado el 1 de mayo de 1998

Further Characterization of the Major and Minor RabbitFMO1Promoters and Identification of both Positive and Negative Distal Regulatory Elements ⬇️

artículo científico publicado el 1 de octubre de 1997

FutureTox III: Bridges for Translation.

artículo científico publicado en 2016

Gene structure and nucleotide sequence for rat cytochrome P-450c.

artículo científico publicado en 1985

Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I.

artículo científico publicado en 1989

Hepatic differentiation of amniotic epithelial cells

artículo científico publicado en 2011

Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes

artículo científico publicado en 2012

Human Hepatic CYP2E1 Expression during Development

artículo científico publicado el 1 de octubre de 2003

Human hepatic UGT2B15 developmental expression

artículo científico publicado en 2014

Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression

artículo científico publicado en 2002

Identification of multiple regulatory elements on the human cytochrome P450IA1 gene

artículo científico publicado en 1988

Identification of tissue-specific DNase I hypersensitive sites in the rabbit flavin-containing monooxygenase form 2 gene.

artículo científico publicado en 1996

Implication of the "4S" polycyclic aromatic hydrocarbon binding protein in the transregulation of rat cytochrome P-450c expression

scientific article published in 1985

Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines.

artículo científico publicado en 1988

Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells.

artículo científico publicado en 2001

Inhibition of metabolism-mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma (line P815) cells

artículo científico publicado en 1982

Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards

artículo científico publicado en 2016

Large-scale purification of plasmid DNA by anion-exchange high-performance liquid chromatography

scientific article published on 01 March 1992

Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.

artículo científico publicado en 2006

Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: Expression of a 4-kilobase messenger RNA ⬇️

artículo científico publicado el 1 de diciembre de 1983

NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of fluoxetine.

artículo científico publicado en 2004

Ontogeny of human hepatic cytochromes P450.

artículo científico publicado en 2007

Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin

artículo científico publicado en 2015

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells

artículo científico publicado en 2015

Partial Characterization of the Human CYP1A1 Negatively Acting Transcription Factor and Mutational Analysis of Its Cognate DNA Recognition Sequence ⬇️

artículo científico publicado el 1 de septiembre de 1995

Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model

scientific article published on 07 June 2006

Prediction of Warfarin Dose in Pediatric Patients: An Evaluation of the Predictive Performance of Several Models.

artículo científico publicado en 2016

Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes

artículo científico publicado en 1986

Regulation of flavin-containing monooxygenase 1 expression by ying yang 1 and hepatic nuclear factors 1 and 4.

artículo científico publicado en 2001

Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny

artículo científico publicado en 2016

Specific nuclear protein binding to a negative regulatory element on the human CYP1A1 gene

scientific article published on 01 August 1993

Structural details of the human cytochrome P-450c gene

scientific article published on 01 July 1987

The Impact of Scaling Factor Variability on Risk-Relevant Pharmacokinetic Outcomes in Children: A Case Study Using Bromodichloromethane (BDCM)

artículo científico publicado en 2019

The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants.

artículo científico publicado en 2011

The characterization of an inhibitory complex formed with cytochrome P-450 and a metabolite of 1,1-disubstituted hydrazines

artículo científico publicado en 1980

The molecular cloning of cytochrome P-450c information

artículo científico publicado en 1981

The oxidation of hydrazine derivatives catalyzed by the purified liver microsomal FAD-containing monooxygenase

artículo científico publicado en 1981

Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit

artículo científico publicado en 1995

Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.

artículo científico publicado en 2014

Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?

scientific article published on 01 June 1997

Lista de obras de Ronald N. Hines

A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing

A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia

A Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes

A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake

A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities

Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.

Altered regulation of the cytochrome P4501A1 gene: novel inducer-independent gene expression in pulmonary carcinoma cell lines

Application of epigenetic data in human health risk assessment

Approaches for assessing risks to sensitive populations: lessons learned from evaluating risks in the pediatric population

Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression

Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.

Demonstration of microsomal oxygenation of the benzo ring of 6-nitrobenzo[a]pyrene by thin-layer chromatography

Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

Developmental Expression of the Cytosolic Sulfotransferases in Human Liver.

Developmental expression of drug metabolizing enzymes: impact on disposition in neonates and young children.

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver

Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.

Functional characterization of the human CYP1A1 negative regulatory element: modulation of Ah receptor mediated transcriptional activity ⬇️

Further Characterization of the Major and Minor RabbitFMO1Promoters and Identification of both Positive and Negative Distal Regulatory Elements ⬇️

FutureTox III: Bridges for Translation.

Gene structure and nucleotide sequence for rat cytochrome P-450c.

Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I.

Hepatic differentiation of amniotic epithelial cells

Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes

Human Hepatic CYP2E1 Expression during Development

Human hepatic UGT2B15 developmental expression

Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression

Identification of multiple regulatory elements on the human cytochrome P450IA1 gene

Identification of tissue-specific DNase I hypersensitive sites in the rabbit flavin-containing monooxygenase form 2 gene.

Implication of the "4S" polycyclic aromatic hydrocarbon binding protein in the transregulation of rat cytochrome P-450c expression

Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines.

Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells.

Inhibition of metabolism-mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma (line P815) cells

Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards

Large-scale purification of plasmid DNA by anion-exchange high-performance liquid chromatography

Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.

Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: Expression of a 4-kilobase messenger RNA ⬇️

NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of fluoxetine.

Ontogeny of human hepatic cytochromes P450.

Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells

Partial Characterization of the Human CYP1A1 Negatively Acting Transcription Factor and Mutational Analysis of Its Cognate DNA Recognition Sequence ⬇️

Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model

Prediction of Warfarin Dose in Pediatric Patients: An Evaluation of the Predictive Performance of Several Models.

Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes

Regulation of flavin-containing monooxygenase 1 expression by ying yang 1 and hepatic nuclear factors 1 and 4.

Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny

Specific nuclear protein binding to a negative regulatory element on the human CYP1A1 gene

Structural details of the human cytochrome P-450c gene

The Impact of Scaling Factor Variability on Risk-Relevant Pharmacokinetic Outcomes in Children: A Case Study Using Bromodichloromethane (BDCM)

The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants.

The characterization of an inhibitory complex formed with cytochrome P-450 and a metabolite of 1,1-disubstituted hydrazines

The molecular cloning of cytochrome P-450c information

The oxidation of hydrazine derivatives catalyzed by the purified liver microsomal FAD-containing monooxygenase

Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit

Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.

Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?