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Lista de obras de Rolf Bjerkvig

A cerebral glioma model for experimental therapy and in vivo invasion studies in syngeneic BD IX rats

artículo científico publicado en 1990

A metalloproteinase, capable of destroying cultured brain tissue isolated from rat glioma cells

artículo científico publicado en 1991

A new chance for EGFR inhibition in glioblastoma?

scientific article published on 01 December 2019

A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients

article

A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions.

artículo científico publicado en 2008

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

artículo científico publicado en 2013

A reproducible brain tumour model established from human glioblastoma biopsies

artículo científico publicado en 2009

A validated prognostic nomogram for patients with newly diagnosed lower-grade gliomas in a large-scale Asian cohort

scientific article published on 06 February 2020

AI-10DISTINCT EGFR SIGNALING IN GLIOBLASTOMA: WILD-TYPE EGFR PROMOTES INVASION WHILE EGFRvIII DRIVES PROTOTYPICAL SFK c-SRC ACTIVATION TO FOSTER ANGIOGENESIS.

artículo científico publicado en 2014

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

artículo científico publicado en 2020

ANGI-02. INHIBITION OF APLN-APLNR SIGNALLING BLOCKS TUMOUR ANGIOGENESIS AND ATTENUATES INVASIVE GLIOBLASTOMA GROWTH

artículo científico publicado en 2017

ANGI-06. THE MATRIX PROTEIN THROMBOSPONDIN-1 IS A DOWNSTREAM TARGET OF TGF-β INDUCED MICROTUBE FORMATION IN GLIOBLASTOMA

artículo científico publicado en 2018

ATPS-59IMPROVING EFFICACY OF BEVACIZUMAB TREATMENT IN GLIOBLASTOMA BY TARGETING HIF1 ALPHA.

artículo científico publicado en 2015

Abstract 4036: Drug repurposing to treat melanoma brain metastases

Abstracts of the 10th Congress of the European Association of NeuroOncology. Marseille, France. September 6-9, 2012

artículo científico publicado en 2012

Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein

artículo científico publicado en 2009

Adeno-associated viral vectors penetrate human solid tumor tissue in vivo more effectively than adenoviral vectors

artículo científico publicado en 2002

Adeno-associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human glioma

artículo científico publicado en 2006

Alginate-encapsulated producer cells: a potential new approach for the treatment of malignant brain tumors.

artículo científico publicado en 2000

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

artículo científico publicado en 2017

Amplifying small amounts of tumor DNA allows detection of DNA copy number abberations with array-CGH.

artículo científico publicado en 2008

Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI.

artículo científico publicado en 2012

Angiogenesis-independent tumor growth mediated by stem-like cancer cells

artículo científico publicado en 2006

Anti-GM2 monoclonal antibodies induce necrosis in GM2-rich cultures of a human glioma cell line

artículo científico publicado en 1991

Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms

artículo científico publicado en 2009

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

artículo científico publicado en 2011

Antitumor efficacy improved by local delivery of species-specific endostatin

artículo científico publicado en 2006

Automated tracking of nanoparticle-labeled melanoma cells improves the predictive power of a brain metastasis model

artículo científico publicado en 2013

BM-34NEW USES OF OLD DRUGS FOR THE CLINICAL TREATMENT OF BRAIN METASTASES

BMET-34DRUG REPURPOSING DISCOVERS BETA-SITOSTEROL AS AN EFFECTIVE THERAPEUTIC AGENT AGAINST MELANOMA BRAIN METASTASES IN VIVO.

artículo científico publicado en 2015

Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment?

artículo científico publicado en 2014

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

artículo científico publicado en 2014

Bi-specific tenascin-C and fibronectin targeted peptide for solid tumor delivery

artículo científico publicado en 2019

Bromelain Reversibly Inhibits Invasive Properties of Glioma Cells

artículo científico publicado el 1 de noviembre de 2001

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

artículo científico publicado en 2008

CD47 antibody inhibits tumor recurrence in a clinical relevant glioblastoma animal model.

artículo científico publicado en 2015

CELL BIOLOGY AND SIGNALING

article

CSIG-28. LONG NONCODING RNA MIR22 HOST GENE-DERIVED miR-22-3p AND miR-22-5p PROMOTE PROLIFERATION, INVASION AND SELF-RENEWAL IN HUMAN GLIOMAS VIA Wnt/-CATENIN SIGNALING

CSIG-37. TGF-β PROMOTES MEMBRANE TUBE FORMATION IN GLIOBLASTOMA THAT CONTRIBUTES TO INVASION AND THERAPY RESISTANCE

Cancer initiation and progression: involvement of stem cells and the microenvironment

artículo científico publicado en 2007

Cancer stem cells and angiogenesis

artículo científico publicado en 2009

Cathepsin L silencing enhances arsenic trioxide mediated in vitro cytotoxicity and apoptosis in glioblastoma U87MG spheroids

artículo científico publicado en 2013

Cathepsin L silencing increases As2O3 toxicity in malignantly transformed pilocytic astrocytoma MPA58 cells by activating caspases 3/7.

artículo científico publicado en 2017

Cell and tissue culture of the central nervous system: recent developments and current applications

artículo científico publicado en 1985

Cell encapsulation technology as a therapeutic strategy for CNS malignancies

artículo científico publicado en 2001

Cell therapies for glioblastoma

artículo científico publicado en 2006

Cell-cycle regulation and dynamics of cytoplasmic compartments containing the promyelocytic leukemia protein and nucleoporins

artículo científico publicado en 2009

Cells encapsulated in alginate: a potential system for delivery of recombinant proteins to malignant brain tumours

artículo científico publicado en 1999

Cellular Host Responses to Gliomas

artículo científico publicado el 23 de abril de 2012

Cellular effects of oncolytic viral therapy on the glioblastoma microenvironment

artículo científico publicado en 2009

Characteristics of human and rat glioma cells grown in a defined medium

artículo científico publicado en 1988

Characterization of NCAM expression and function in BT4C and BT4Cn glioma cells

artículo científico publicado en 1991

Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.

artículo científico publicado en 2010

Combretastatin A-4 and hyperthermia;a potent combination for the treatment of solid tumors

artículo científico publicado en 2001

Comment to: "Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro" by Z. Ren et al. Exp. Cell Res. 317 (2011) 2950-2957: spontaneous transformation of mesenchymal stem cells in culture: facts or fiction?

artículo científico publicado en 2011

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma

artículo científico publicado en 2015

Correction: A Novel, Diffusely Infiltrative Xenograft Model of Human Anaplastic Oligodendroglioma with Mutations in FUBP1, CIC, and IDH1.

artículo científico publicado en 2013

Correction: Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression

artículo científico publicado en 2015

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Critical appraisal of the side population assay in stem cell and cancer stem cell research

artículo científico publicado en 2011

Cryopreservation of alginate-encapsulated recombinant cells for antiangiogenic therapy

artículo científico publicado en 2004

DDEL-19PENETRATION OF HOMING PEPTIDE-FUNCTIONALIZED NANOPARTICLES TO GLIOMA SPHEROIDS IN VITRO.

artículo científico publicado en 2015

DDIS-21. APPLICATION OF A FUNCTIONAL GENETICS APPROACH TO IDENTIFY PHARMACOLOGICAL INHIBITORS OF HIF-1α

article published in 2017

DNA content and chromosomal composition of malignant human gliomas.

artículo científico publicado en 1985

DNA content and chromosomes in permanent cultured cell lines derived from malignant human gliomas

artículo científico publicado en 1987

DNA methylation-based classification of central nervous system tumours

artículo científico publicado en 2018

DNA repair and cancer stem-like cells--potential partners in glioma drug resistance?

artículo científico publicado en 2008

DS-04DOPAMINE ADDICTION IN GLIOBLASTOMA MULTIFORME DURING CHEMOTHERAPY IS MEDIATED BY A DRD2/β-ARRESTIN/AKT SIGNALING COMPLEX.

artículo científico publicado en 2014

Deciphering the complex role of thrombospondin-1 in glioblastoma development

artículo científico publicado en 2019

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes

scientific article published on 04 June 2019

Deletion-mutant epidermal growth factor receptor in human gliomas: Effect of type II mutation on receptor function

artículo científico publicado el 15 de agosto de 1991

Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma

artículo científico publicado en 2011

Distribution patterns of the anti-angiogenic protein ADAMTS-1 during rat development

artículo científico publicado en 2005

Dynamic determination of human glioma invasion in vitro

artículo científico publicado en 1998

EGFR heterogeneity and implications for therapeutic intervention in glioblastoma

artículo científico publicado en 2017

EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

artículo científico publicado en 2013

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

artículo científico publicado en 2016

EXTH-68. RECURRENT XENOGRAFT TUMORS UPREGULATE EGFR AFTER LENTIVIRAL VECTOR MEDIATED SUICIDE GENE THERAPY FOR GLIOBLASTOMA, BUT ARE RESISTANT TO COMBINATORIAL TREATMENT WITH ERLOTINIB

Effect of alkyl-lysophospholipid on glioblastoma cell invasion into fetal rat brain tissue in vitro

artículo científico publicado en 1991

Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro.

artículo científico publicado en 1990

Effective Treatment of Metastatic Melanoma by Combining MAPK and PI3K Signaling Pathway Inhibitors

artículo científico publicado en 2019

Effects of DFMO on glioma cell proliferation, migration and invasion in vitro

artículo científico publicado el 1 de enero de 1998

Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro

artículo científico publicado en 1993

Effects of growth factors on a human glioma cell line during invasion into rat brain aggregates in culture

artículo científico publicado en 1992

Effects of high and low single dose irradiation on glioma spheroid invasion into normal rat brain tissue in vitro

artículo científico publicado el 1 de septiembre de 1992

Effects of photodynamic therapy on glioma spheroids

artículo científico publicado el 1 de junio de 1997

Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma

artículo científico publicado en 2002

Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression

artículo científico publicado en 2015

Epidermal growth factor and laminin receptors contribute to migratory and invasive properties of gliomas

artículo científico publicado en 1997

Evidence for a secreted chemorepellent that directs glioma cell invasion

artículo científico publicado en 2004

Expansive growth of two glioblastoma stem-like cell lines is mediated by bFGF and not by EGF.

artículo científico publicado en 2013

Experimental therapies: gene therapies and oncolytic viruses

artículo científico publicado en 2016

Expression of extracellular matrix components in a highly infiltrative in vivo glioma model

artículo científico publicado en 2002

Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma

artículo científico publicado en 2011

Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1.

artículo científico publicado en 2006

Extracellular matrix-induced cell migration from glioblastoma biopsy specimens in vitro

artículo científico publicado en 1999

Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model

artículo científico publicado en 2013

Glioblastoma: a prognostic value of AMT-PET?

scientific article published on 01 February 2019

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

scientific article published on 24 October 2013

Glioma cell interactions with fetal rat brain aggregates in vitro and with brain tissue in vivo

artículo científico publicado en 1986

Glioma cell invasion visualized by scanning confocal laser microscopy in an in vitro co-culture system

artículo científico publicado en 1995

Glioma cell populations grouped by different cell type markers drive brain tumor growth

artículo científico publicado en 2010

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

artículo científico publicado en 2014

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

artículo científico publicado en 2015

Growth arrest and polyploidization induced by metahalone microtubule inhibitors on rat glioma cells in culture

artículo científico publicado en 1986

HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects

artículo científico publicado en 2003

Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions

artículo científico publicado en 2000

Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion

artículo científico publicado en 1994

Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype

artículo científico

Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival

artículo científico publicado en 2004

Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery

artículo científico publicado en 2006

Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors

artículo científico publicado en 2007

Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats

artículo científico publicado en 2007

IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

artículo científico publicado en 2014

Identification of a Blood-Based Protein Biomarker Panel for Lung Cancer Detection

artículo científico publicado en 2020

Identification of a novel lytic peptide for the treatment of solid tumours.

artículo científico publicado en 2014

Imaging of experimental rat gliomas using a clinical MR scanner

artículo científico publicado en 2003

Immunocytochemical characterization of extracellular matrix proteins expressed by cultured glioma cells

artículo científico publicado en 1989

Immunohistochemical expression of stem cell, endothelial cell, and chemosensitivity markers in primary glioma spheroids cultured in serum-containing and serum-free medium

artículo científico publicado en 2010

Immunolocalization of extracellular matrix proteins during brain tumor invasion in BD IX rats.

artículo científico publicado en 1989

Improved Drug Delivery to Brain Metastases by Peptide-Mediated Permeabilization of the Blood-Brain Barrier

scientific article published on 29 August 2019

In vitro and in vivo models for the study of brain tumour invasion

artículo científico publicado el 1 de noviembre de 1997

In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways

artículo científico publicado en 2014

In vivo animal models for studying brain metastasis: value and limitations

artículo científico

In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme.

artículo científico publicado en 2013

In vivo models of primary brain tumors: pitfalls and perspectives

artículo científico publicado el 7 de junio de 2012

Infection of rat brain cell aggregates with neurovirulent and nonneurovirulent strains of herpes simplex virus type 1.

artículo científico publicado en 1999

Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer

artículo científico publicado en 2015

Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis.

artículo científico publicado en 2012

Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy

scientific article published on 17 August 2018

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

Interaction between human brain tumour biopsies and fetal rat brain tissue in vitro

artículo científico publicado en 1990

Interaction between human medulloblastomas and foetal rat brain aggregates in vitro

artículo científico publicado en 1994

Interaction between rat glioma cells and normal rat brain tissue in organ culture

artículo científico publicado en 1985

Interactions between fetal rat brain cells and mature brain tissue in vivo and in vitro

artículo científico publicado en 1994

Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

artículo científico publicado en 2015

Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling

artículo científico publicado en 2020

Interstitial fluid: the overlooked component of the tumor microenvironment?

artículo científico publicado en 2010

Intravital microscopy reveals novel antivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells

artículo científico publicado en 2001

Invasive glioma cells in tissue culture

artículo científico publicado en 1990

Invasiveness by lacZ transfected non-small cell lung cancer cells into human bronchial tissues in vitro

artículo científico publicado el 1 de julio de 1998

Invasiveness of primary brain tumors

artículo científico publicado en 1984

Isolation and characterization of a metalloproteinase secreted by rat glioma cells in serum-free culture

artículo científico publicado en 1990

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma

artículo científico publicado en 2017

Laminin expression by glial fibrillary acidic protein positive cells in human gliomas

artículo científico publicado en 1999

Laminin: a potential inhibitor of rat glioma cell invasion in vitro

artículo científico publicado en 1994

Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells

artículo científico publicado en 2016

Leptomeningeal tissue: a barrier against brain tumor cell invasion

artículo científico publicado en 1994

Local endostatin treatment of gliomas administered by microencapsulated producer cells

artículo científico publicado en 2001

Localised delivery of therapeutic agents to CNS malignancies: old and new approaches

artículo científico publicado en 2002

Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB Signaling

artículo científico publicado en 2019

Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation

artículo científico publicado en 2009

Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma

scientific article published on 01 July 2019

Loss of GFAP expression in high-grade astrocytomas does not contribute to tumor development or progression

artículo científico publicado en 2003

Loss of adipocyte specification and necrosis augment tumor-associated inflammation

artículo científico publicado en 2013

Lymphangiogenesis in colorectal cancer--prognostic and therapeutic aspects

artículo científico publicado en 2007

MAPPING THE GLIOBLASTOMA METABOLOME AFTER BEVACIZUMAB THERAPY BY 13C6-GLUCOSE METABOLOMIC FLUX ANALYSIS.

artículo científico publicado en 2014

METB-09IDENTIFYING NOVEL VULNERABILITIES IN OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT GLIOMA.

artículo científico publicado en 2015

Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway

article published in 2018

Mechanisms of tumor cell invasion and angiogenesis in the central nervous system

artículo científico publicado el 1 de mayo de 2003

Melanoma brain metastasis is independent of lactate dehydrogenase A expression

artículo científico publicado en 2015

Mesenchymal stem cell signaling in cancer progression

artículo científico publicado el 9 de abril de 2012

Metabolic effects of 3-thia fatty acid in cancer cells

scientific article published on 01 January 1999

Migratory pattern of fetal rat brain cells and human glioma cells in the adult rat brain.

artículo científico publicado en 1993

Migratory patterns of lac-z transfected human glioma cells in the rat brain

artículo científico publicado en 1995

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

scientific article published on 25 March 2016

Molecular mechanisms of temozolomide resistance in glioblastoma multiforme

artículo científico publicado en 2012

Multicellular tumor spheroids from human gliomas maintained in organ culture

artículo científico publicado en 1990

Multicellular tumor spheroids in serum-free culture

artículo científico publicado en 1989

Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies.

artículo científico publicado en 2014

Mutant IDH1 Differently Affects Redox State and Metabolism in Glial Cells of Normal and Tumor Origin

artículo científico publicado en 2019

NG2 expression regulates vascular morphology and function in human brain tumours

artículo científico publicado en 2006

NG2 proteoglycan promotes angiogenesis-dependent tumor growth in CNS by sequestering angiostatin.

artículo científico publicado en 2002

NUMB does not impair growth and differentiation status of experimental gliomas

artículo científico publicado en 2011

Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases

artículo científico publicado en 2010

Non-small-cell lung carcinoma cells invade human bronchial mucosa In vitro

artículo científico publicado el 1 de abril de 1998

Nonadhesive stationary organ culture of human bronchial mucosa

scientific article published on 01 August 1996

Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing

artículo científico publicado en 2013

O10.03PHYSIOLOGICAL AND BIOLOGICAL RESPONSES OF HUMAN GLIOBLASTOMAS TO BEVACIZUMAB TREATMENT ASSESSED BY METABOLOMIC FLUX ANALYSIS.

artículo científico publicado en 2014

O4.09IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

artículo científico publicado en 2014

Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma

artículo científico publicado en 2008

Opinion: the origin of the cancer stem cell: current controversies and new insights

artículo científico publicado en 2005

Organ culture of a glioblastoma from a patient with an unusually long survival

artículo científico publicado en 1994

Oxygenation and response to irradiation of organotypic multicellular spheroids of human glioma.

artículo científico publicado en 2003

P01.19A GENOME-WIDE RNAI SYNTHETIC LETHAL SCREEN FOR SENSITIZERS OF GLIOBLASTOMA MULTIFORME TO TEMOZOLOMIDE.

artículo científico publicado en 2014

P04.44 Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma

P04.64 Molecular characterization of glioma patient derived orthotopic xenografts to improve outcome of preclinical studies

P04.87 Delineating the invasive component of human brain tumors using brain organoids

P05.01 Patient-derived xenograft (PDX) model of glioblastoma: from basic research to preclinical studies.

artículo científico publicado en 2016

P08.42 Long-term treatment with Valganciclovir improves lentiviral suicide gene therapy for glioblastoma.

artículo científico publicado en 2017

P13.04 K16ApoE increases drug-delivery across the blood brain barrier in an animal model of brain metastases

artículo científico publicado en 2017

P16.24MULTIMODAL IMAGING ELUCIDATES PHYSIOLOGICAL AND METABOLIC CHANGES INDUCED BY ANTI-ANGIOGENIC THERAPY IN GLIOBLASTOMA.

artículo científico publicado en 2014

P17.30ONCOGENIC EGFRVIII DRIVES PROTOTYPICAL SFK C-SRC ACTIVATION TO PROMOTE GLIOBLASTOMA ANGIOGENESIS.

artículo científico publicado en 2014

PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1

artículo científico publicado en 2019

PML-nuclear bodies accumulate DNA in response to polyomavirus BK and simian virus 40 replication

artículo científico publicado en 2004

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

scientific article published on 03 October 2020

Peptide-guided nanoparticles for glioblastoma targeting

artículo científico publicado en 2019

Phagocytic capacity of normal and malignant rat glial cells in culture.

artículo científico publicado en 1987

Poorly oxidizable fatty acid analogues inhibit the proliferation of cancer cells in culture

artículo científico publicado en 1999

Practical Considerations for Omics Experiments in Biomedical Sciences.

artículo científico

Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation

artículo científico publicado en 2006

Proliferation, migration and invasion of human glioma cells exposed to antifolate drugs

artículo científico publicado en 1993

Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro

artículo científico publicado en 1997

Promyelocytic leukemia nuclear bodies are predetermined processing sites for damaged DNA

scientific article published on 25 July 2006

Prospects for Delivery of Recombinant Angiostatin by Cell-Encapsulation Therapy

artículo científico publicado el 10 de octubre de 2003

Protein disulfide isomerase expression is related to the invasive properties of malignant glioma

artículo científico publicado en 2006

Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis

artículo científico publicado en 2016

Reaggregation of fetal rat brain cells in a stationary culture system. I: Methodology and cell identification

artículo científico publicado en 1986

Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma

scientific article published on 28 November 2019

Release of replication-deficient retroviruses from a packaging cell line: interaction with glioma tumor spheroids in vitro

artículo científico publicado en 1997

Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy

artículo científico publicado en 2009

Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres

artículo científico publicado en 2007

Retroviral transfection of the lacZ gene from Liz-9 packaging cells to glioma spheroids

artículo científico publicado en 1999

Role of high molecular weight extracellular matrix proteins in glioma cell migration

artículo científico publicado en 1997

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells

artículo científico publicado en 2013

Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion

artículo científico publicado en 2018

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

artículo científico publicado en 2010

Spontaneous Transformation of Stem Cells In Vitro and the Issue of Cross-Contamination

artículo científico publicado el 15 de agosto de 2012

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

scientific article published on 16 April 2019

Stimulation of extracellular matrix components in the normal brain by invading glioma cells

artículo científico publicado el 16 de marzo de 1998

Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies

artículo científico publicado en 1996

Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein

artículo científico publicado el 21 de noviembre de 2010

Suicide gene therapy for the treatment of high-grade glioma: past lessons, present trends, and future prospects

artículo científico publicado en 2020

Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy

artículo científico publicado en 2017

TM-14 * THE ANGIOGENIC SWITCH LEADS TO A METABOLIC SWITCH IN HUMAN GLIOBLASTOMA

TMOD-29. MOLECULAR CHARACTERIZATION OF GLIOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS: FROM BASIC RESEARCH TO PRECLINICAL STUDIES

TMOD-34. IMPROVED TREATMENT OF MELANOMA BRAIN METASTASIS USING A SYNTHETIC PEPTIDE

TUMOR MODELS (IN VIVO/IN VITRO)

Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM).

artículo científico publicado en 2015

Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma

scientific article published on 04 February 2019

Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma

artículo científico publicado en 2011

The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells

artículo científico publicado en 2012

The angiogenic switch leads to a metabolic shift in human glioblastoma

artículo científico publicado en 2016

The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

artículo científico publicado en 2017

The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling

artículo científico publicado en 2012

The brain slice chamber, a novel variation of the Boyden Chamber Assay, allows time-dependent quantification of glioma invasion into mammalian brain in vitro

artículo científico publicado en 2005

The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours.

artículo científico publicado en 2002

The glioma-associated gangliosides 3'-isoLM1, GD3 and GM2 show selective area expression in human glioblastoma xenografts in nude rat brains

artículo científico publicado en 2001

The invasive proteome of glioblastoma revealed by laser-capture microdissection

artículo científico publicado en 2019

The lac-z reporter gene: a tool for in vitro studies of malignant glioma cell invasion.

artículo científico publicado en 1996

The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling

artículo científico publicado en 2008

The regulation of cysteine cathepsins and cystatins in human gliomas

artículo científico publicado el 9 de marzo de 2012

The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors

artículo científico publicado en 2017

The role of growth factors in the malignant and invasive progression of intrinsic brain tumours

artículo científico publicado el 1 de noviembre de 1997

Therapeutic Effect of Cabazitaxel and Blood-Brain Barrier opening in a Patient-Derived Glioblastoma Model

article published in 2019

Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma

artículo científico publicado en 2019

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide

artículo científico publicado en 2018

Three-dimensional growth of glial cell lines affects growth factor and growth factor receptor mRNA levels

artículo científico publicado en 1994

Transfection of glioma cells with the neural-cell adhesion molecule NCAM: effect on glioma-cell invasion and growth in vivo

artículo científico publicado en 1994

Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells

artículo científico publicado en 2015

Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination

artículo científico publicado en 2017

Tumor cell invasion and angiogenesis in the central nervous system

artículo científico publicado el 1 de mayo de 1997

Tumor vasculature is targeted by the combination of combretastatin A-4 and hyperthermia

artículo científico publicado el 1 de diciembre de 2001

Tumor vasculature: the Achilles' heel of cancer?

artículo científico publicado el 2 de noviembre de 2012

Tumor versus stromal cells in culture--survival of the fittest?

artículo científico publicado en 2013

Tumor-penetrating peptide for systemic targeting of Tenascin-C

scientific article published on 02 April 2020

Tumour fragment spheroids from human non-small-cell lung cancer maintained in organ culture

scientific article published on 01 January 1995

Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics

artículo científico publicado en 2008

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

artículo científico publicado en 2014

Vinblastine and hyperthermia target the neovasculature in BT(4)AN rat gliomas: therapeutic implications of the vascular phenotype

artículo científico publicado en 2001

Whipple's disease. Demonstration of a persisting monocyte and macrophage dysfunction

scientific article published on 01 June 1988

Whole genomes redefine the mutational landscape of pancreatic cancer

artículo científico publicado en 2015

Widespread dispersion of adeno-associated virus serotype 1 and adeno-associated virus serotype 6 vectors in the rat central nervous system and in human glioblastoma multiforme xenografts

artículo científico publicado en 2005

iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype

artículo científico publicado en 2009

lacZ-neoR transfected glioma cells in syngeneic rats: growth pattern and characterization of the host immune response against cells transplanted inside and outside the CNS.

artículo científico publicado en 2000

αB-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells

artículo científico publicado el 2 de septiembre de 2010