Lista de obras - Jin Chen - Dominio Público Uruguay

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

artículo científico publicado en 2005

An enhancer element in the EphA2 (Eck) gene sufficient for rhombomere-specific expression is activated by HOXA1 and HOXB1 homeobox proteins.

artículo científico publicado en 1998

Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium

artículo científico publicado en 2010

Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable

scientific journal article

B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.

artículo científico publicado en 2018

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis

artículo científico publicado en 2002

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

artículo científico publicado en 2002

CD148 tyrosine phosphatase promotes cadherin cell adhesion

artículo científico publicado en 2014

Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli

artículo científico publicado en 1989

Constitutive expression of BCL-X(L) in the T lineage attenuates collagen-induced arthritis in Bcl-X(L) transgenic mice

artículo científico publicado en 2002

Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.

artículo científico publicado en 2010

Determination of the CD148-Interacting Region in Thrombospondin-1

artículo científico publicado en 2016

Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo

scientific article published on 13 May 2019

EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer

artículo científico publicado en 2016

Effects of cancer-associated EPHA3 mutations on lung cancer.

artículo científico publicado en 2012

Elevated Slit2 Activity Impairs VEGF-Induced Angiogenesis and Tumor Neovascularization in EphA2-Deficient Endothelium

artículo científico publicado en 2014

Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.

artículo científico publicado en 2009

Eph Receptor Tyrosine Kinases in Tumor Immunity

artículo científico publicado en 2016

Eph receptor tyrosine kinases in angiogenesis: from development to disease.

artículo científico publicado en 2004

Eph receptor tyrosine kinases in cancer stem cells

artículo científico publicado en 2014

Eph receptor tyrosine kinases in tumor and tumor microenvironment

artículo científico publicado en 2004

Eph receptors and Ephrins in cancer: common themes and controversies.

artículo científico publicado en 2008

Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.

artículo científico publicado en 2008

Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.

artículo científico publicado en 2011

EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.

artículo científico publicado en 2017

EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis

artículo científico publicado en 2012

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

artículo científico publicado en 2005

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

artículo científico publicado en 2004

EphA2 signaling following endocytosis: role of Tiam1.

artículo científico publicado en 2013

Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice

artículo científico publicado en 2006

Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis.

artículo científico publicado en 2002

Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase.

artículo científico publicado en 2001

Essential role of T cell NF-kappa B activation in collagen-induced arthritis

scientific article published on 01 August 1999

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis

scientific journal article

Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes

artículo científico publicado en 2006

Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC.

artículo científico publicado en 2014

Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion.

artículo científico publicado en 1996

Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo

scientific article published on 12 May 2009

Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase.

artículo científico publicado en 2008

Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

artículo científico publicado en 2005

In vivo function of an interleukin 2 receptor beta chain (IL-2Rbeta)/IL-4Ralpha cytokine receptor chimera potentiates allergic airway disease.

artículo científico publicado en 1998

In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts.

artículo científico publicado en 2014

Induction of S.cerevisiae MAG 3-methyladenine DNA glycosylase transcript levels in response to DNA damage

artículo científico publicado en 1991

Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors

artículo científico publicado en 2003

Inhibition of retinal neovascularization by soluble EphA2 receptor

artículo científico publicado en 2005

JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer

artículo científico publicado en 2014

Keratinocyte transglutaminase: regulation and release

artículo científico publicado en 1988

LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).

artículo científico publicado en 2016

Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis

artículo científico publicado en 2009

Microenvironmental Metabolism Regulates Antitumor Immunity

artículo científico publicado en 2019

Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

artículo científico publicado en 2008

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function

artículo científico publicado en 2006

Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer

artículo científico publicado en 2020

Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylthymine DNA repair methyltransferase gene

artículo científico publicado en 1991

Production of germ-line chimeras in zebrafish by cell transplants from genetically pigmented to albino embryos

scientific article published on May 1992

Radiation Response and Reliability of High Speed AlGaN/GaN HEMTs ⬇️

doctoral dissertation

Radiation response and reliability of AlGaN/GaN HEMTS ⬇️

master's thesis

Redirection of T cell effector function in vivo and enhanced collagen-induced arthritis mediated by an IL-2R beta/IL-4R alpha chimeric cytokine receptor transgene

artículo científico publicado en 2001

Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation

artículo científico publicado en 2006

Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.

artículo científico publicado en 2015

Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1

scientific journal article

Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase

scientific journal article

Regulation of tumor initiation and metastatic progression by Eph receptor tyrosine kinases.

artículo científico publicado en 2012

Retrovirus gene traps

artículo científico publicado en 1995

Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway.

artículo científico publicado en 2004

Rictor amplification promotes NSCLC cell proliferation through formation and activation of mTORC2 at the expense of mTORC1

scientific article published on 14 August 2020

Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.

artículo científico publicado en 1990

Selective targeting p53WT lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA.

artículo científico publicado en 2017

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

artículo científico publicado en 2002

Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers

artículo científico publicado en 2017

The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells

artículo científico publicado en 2015

The Ephrin-A1/EPHA2 Signaling Axis Regulates Glutamine Metabolism in HER2-Positive Breast Cancer.

artículo científico publicado en 2016

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

artículo científico publicado en 2012

The ephrins and Eph receptors in angiogenesis

artículo científico publicado en 2002

The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.

artículo científico publicado en 2017

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

artículo científico publicado en 2008

Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis

artículo científico publicado en 2003

Tie2 signaling regulates osteoclastogenesis and osteolytic bone invasion of breast cancer

artículo científico publicado en 2010

Transcriptional specificity of the pluripotent embryonic stem cell

artículo científico publicado en 1996

Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism.

artículo científico publicado en 2001

VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity

artículo científico publicado en 2012

Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia

artículo científico publicado en 2012

mTORC1 and mTORC2 in cancer and the tumor microenvironment

artículo científico publicado en 2016

Lista de obras de Jin Chen

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

An enhancer element in the EphA2 (Eck) gene sufficient for rhombomere-specific expression is activated by HOXA1 and HOXB1 homeobox proteins.

Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium

Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable

B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

CD148 tyrosine phosphatase promotes cadherin cell adhesion

Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli

Constitutive expression of BCL-X(L) in the T lineage attenuates collagen-induced arthritis in Bcl-X(L) transgenic mice

Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.

Determination of the CD148-Interacting Region in Thrombospondin-1

Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo

EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer

Effects of cancer-associated EPHA3 mutations on lung cancer.

Elevated Slit2 Activity Impairs VEGF-Induced Angiogenesis and Tumor Neovascularization in EphA2-Deficient Endothelium

Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.

Eph Receptor Tyrosine Kinases in Tumor Immunity

Eph receptor tyrosine kinases in angiogenesis: from development to disease.

Eph receptor tyrosine kinases in cancer stem cells

Eph receptor tyrosine kinases in tumor and tumor microenvironment

Eph receptors and Ephrins in cancer: common themes and controversies.

Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.

Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.

EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.

EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

EphA2 signaling following endocytosis: role of Tiam1.

Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice

Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis.

Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase.

Essential role of T cell NF-kappa B activation in collagen-induced arthritis

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis

Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes

Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC.

Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion.

Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo

Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase.

Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

In vivo function of an interleukin 2 receptor beta chain (IL-2Rbeta)/IL-4Ralpha cytokine receptor chimera potentiates allergic airway disease.

In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts.

Induction of S.cerevisiae MAG 3-methyladenine DNA glycosylase transcript levels in response to DNA damage

Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors

Inhibition of retinal neovascularization by soluble EphA2 receptor

JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer

Keratinocyte transglutaminase: regulation and release

LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).

Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis

Microenvironmental Metabolism Regulates Antitumor Immunity

Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function

Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer

Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylthymine DNA repair methyltransferase gene

Production of germ-line chimeras in zebrafish by cell transplants from genetically pigmented to albino embryos

Radiation Response and Reliability of High Speed AlGaN/GaN HEMTs ⬇️

Radiation response and reliability of AlGaN/GaN HEMTS ⬇️

Redirection of T cell effector function in vivo and enhanced collagen-induced arthritis mediated by an IL-2R beta/IL-4R alpha chimeric cytokine receptor transgene

Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation

Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.

Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1

Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase

Regulation of tumor initiation and metastatic progression by Eph receptor tyrosine kinases.

Retrovirus gene traps

Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway.

Rictor amplification promotes NSCLC cell proliferation through formation and activation of mTORC2 at the expense of mTORC1

Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.

Selective targeting p53WT lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA.

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers

The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells

The Ephrin-A1/EPHA2 Signaling Axis Regulates Glutamine Metabolism in HER2-Positive Breast Cancer.

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

The ephrins and Eph receptors in angiogenesis

The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis

Tie2 signaling regulates osteoclastogenesis and osteolytic bone invasion of breast cancer

Transcriptional specificity of the pluripotent embryonic stem cell