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Lista de obras de Matthew Brecher

A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease

artículo científico publicado en 2017

Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change

artículo científico publicado en 2011

Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins

artículo científico publicado en 2015

Cysteines flanking the internal fusion peptide are required for the avian sarcoma/leukosis virus glycoprotein to mediate the lipid mixing stage of fusion with high efficiency

artículo científico publicado en 2008

DNA forms of arboviral RNA genomes are generated following infection in mosquito cell cultures

artículo científico publicado en 2016

Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease

artículo científico publicado en 2017

Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes

artículo científico publicado en 2018

Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase

artículo científico publicado en 2015

Influenza virus pleiomorphy characterized by cryoelectron tomography

artículo científico publicado en 2006

Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase

artículo científico publicado en 2015

Pfit Is a Structurally Novel Crohn's Disease-Associated Superantigen

artículo científico publicado en 2013

Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase

artículo científico publicado en 2014

S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase

artículo científico publicado en 2013

Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12

artículo científico publicado en 2014

Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

artículo científico publicado en 2008

The flavivirus protease as a target for drug discovery

artículo científico publicado en 2013

The primed ebolavirus glycoprotein (19-kilodalton GP1,2): sequence and residues critical for host cell binding

artículo científico publicado en 2009

Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography

artículo científico publicado en 2012