Lista de obras - Eric B Dammer - Dominio Público Uruguay

A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.

artículo científico publicado en 2017

A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation

artículo científico publicado en 2017

Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.

artículo científico publicado en 2014

Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.

artículo científico publicado en 2016

Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.

artículo científico publicado en 2012

Asparaginyl endopeptidase cleaves TDP‐43 in brain ⬇️

artículo científico publicado el 1 de agosto de 2012

At the crossroads of ubiquitin signaling and mass spectrometry

artículo científico publicado en 2010

Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

artículo científico publicado en 2021

Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging

artículo científico

Brain proteome-wide association study implicates novel proteins in depression pathogenesis

artículo científico publicado en 2021

Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy.

artículo científico publicado en 2017

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination

artículo científico publicado en 2012

Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

artículo científico publicado en 2020

Consequences of impaired purine recycling on the proteome in a cellular model of Lesch-Nyhan disease.

artículo científico publicado en 2015

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

artículo científico publicado en 2017

Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

artículo científico publicado en 2018

Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.

artículo científico publicado en 2018

Dysregulated Urinary Arginine Metabolism in Older Adults With Amnestic Mild Cognitive Impairment

artículo científico publicado en 2019

Effects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease

artículo científico publicado en 2018

Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.

artículo científico publicado en 2013

Expression, purification and proteomic analysis of recombinant histone H4 acetylated at lysine 16.

artículo científico publicado en 2013

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.

artículo científico publicado en 2018

Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes ⬇️

artículo científico publicado en 2011

Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis

artículo científico publicado en 2021

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease

artículo científico publicado en 2020

Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.

artículo científico

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis

scientific article published on 28 January 2021

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

artículo científico publicado en 2018

Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue

scientific article published on 29 August 2019

Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level

artículo científico publicado en 2022

Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

artículo científico publicado en 2020

Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age

artículo científico publicado en 2019

Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins

scientific article published on 13 February 2020

Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells

artículo científico publicado en 2020

Multiple Signaling Pathways Coordinate CYP17 Gene Expression in the Human Adrenal Cortex

artículo científico publicado en 2008

Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease

scientific article published on 07 August 2020

Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients

artículo científico publicado en 2022

Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease

artículo científico publicado en 2019

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease

scientific article published on 27 August 2019

Neuron enriched nuclear proteome isolated from human brain.

artículo científico publicado en 2013

Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology.

artículo científico publicado en 2017

Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy

artículo científico publicado en 2017

Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2.

scientific article published on 09 January 2008

Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization

artículo científico publicado en 2021

Protein profiling of active cysteine cathepsins in living cells using an activity-based probe containing a cell-penetrating peptide.

artículo científico publicado en 2012

Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology.

artículo científico publicado en 2011

Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation

artículo científico publicado en 2019

Proteomics of protein post-translational modifications implicated in neurodegeneration

artículo científico publicado en 2014

Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase

artículo científico publicado en 2015

Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

artículo científico publicado en 2020

Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease

artículo científico publicado en 2018

Quantitative Analysis of the Detergent-Insoluble Brain Proteome in Frontotemporal Lobar Degeneration Using SILAC Internal Standards ⬇️

artículo científico publicado el 4 de abril de 2012

Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1

artículo científico publicado en 2020

Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins.

artículo científico publicado en 2014

Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.

artículo científico publicado en 2018

Quantitative proteomics reveals significant changes in cell shape and an energy shift after IPTG induction via an optimized SILAC approach for Escherichia coli

artículo científico publicado en 2013

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease

artículo científico publicado en 2018

Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450scc

artículo científico publicado en 2012

Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

artículo científico publicado en 2020

Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2

artículo científico publicado en 2019

TBK1 interacts with tau and enhances neurodegeneration in tauopathy

artículo científico publicado en 2021

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease

scientific article published on 01 October 2019

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

artículo científico publicado en 2018

The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis

artículo científico publicado en 2013

The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration

artículo científico publicado en 2015

Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.

artículo científico publicado en 2012

Transcriptional regulation of adrenocortical steroidogenic gene expression.

artículo científico publicado en 2007

Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα

scientific article published on 13 July 2019

Transcriptome Network Analysis Identifies CXCL13-CXCR5 Signaling Modules in the Prostate Tumor Immune Microenvironment

artículo científico publicado en 2019

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease

artículo científico publicado en 2013

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.

artículo científico publicado en 2014

Lista de obras de Eric B Dammer

A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.

A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation

Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.

Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.

Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.

Asparaginyl endopeptidase cleaves TDP‐43 in brain ⬇️

At the crossroads of ubiquitin signaling and mass spectrometry

Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging

Brain proteome-wide association study implicates novel proteins in depression pathogenesis

Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy.

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination

Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

Consequences of impaired purine recycling on the proteome in a cellular model of Lesch-Nyhan disease.

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.

Dysregulated Urinary Arginine Metabolism in Older Adults With Amnestic Mild Cognitive Impairment

Effects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease

Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.

Expression, purification and proteomic analysis of recombinant histone H4 acetylated at lysine 16.

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.

Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes ⬇️

Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease

Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue

Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level

Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age

Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins

Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells

Multiple Signaling Pathways Coordinate CYP17 Gene Expression in the Human Adrenal Cortex

Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease

Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients

Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease

Neuron enriched nuclear proteome isolated from human brain.

Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology.

Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy

Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2.

Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization

Protein profiling of active cysteine cathepsins in living cells using an activity-based probe containing a cell-penetrating peptide.

Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology.

Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation

Proteomics of protein post-translational modifications implicated in neurodegeneration

Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase

Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease

Quantitative Analysis of the Detergent-Insoluble Brain Proteome in Frontotemporal Lobar Degeneration Using SILAC Internal Standards ⬇️

Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1

Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins.

Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.

Quantitative proteomics reveals significant changes in cell shape and an energy shift after IPTG induction via an optimized SILAC approach for Escherichia coli

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease

Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450scc

Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2

TBK1 interacts with tau and enhances neurodegeneration in tauopathy

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis

The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration

Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.

Transcriptional regulation of adrenocortical steroidogenic gene expression.

Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα

Transcriptome Network Analysis Identifies CXCL13-CXCR5 Signaling Modules in the Prostate Tumor Immune Microenvironment

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.