Lista de obras - David L. Narum - Dominio Público Uruguay

A Method for Producing Protein Nanoparticles with Applications in Vaccines

artículo científico publicado en 2016

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

artículo científico publicado en 2021

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection

artículo científico

A novel Plasmodium falciparum erythrocyte binding protein-2 (EBP2/BAEBL) involved in erythrocyte receptor binding

artículo científico publicado en 2002

A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

artículo científico publicado en 2010

A recombinant baculovirus-expressed Plasmodium falciparum receptor-binding domain of erythrocyte binding protein EBA-175 biologically mimics native protein. ⬇️

artículo científico publicado en 2000

Absence of antigenic competition in Aotus monkeys immunized with Plasmodium falciparum DNA vaccines delivered as a mixture

artículo científico publicado en 2002

Accelerated and long term stability study of Pfs25-EPA conjugates adjuvanted with Alhydrogel®.

artículo científico publicado en 2017

Addition of CpG ODN to recombinant Pseudomonas aeruginosa ExoProtein A conjugates of AMA1 and Pfs25 greatly increases the number of responders

artículo científico publicado en 2008

Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo

artículo científico publicado en 2010

Analysis of the conformation and function of the Plasmodium falciparum merozoite proteins MTRAP and PTRAMP

artículo científico publicado en 2012

Analysis of the processing of Plasmodium falciparum rhoptry-associated protein 1 and localization of Pr86 to schizont rhoptries and p67 to free merozoites

article

Antibodies against the Plasmodium falciparum receptor binding domain of EBA-175 block invasion pathways that do not involve sialic acids ⬇️

artículo científico publicado en 2000

Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic

artículo científico publicado en 2011

Antibodies to Plasmodium falciparum antigens vary by age and antigen in children in a malaria-holoendemic area of Kenya

artículo científico publicado en 2005

Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malaria

artículo científico publicado en 2011

Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemia

artículo científico publicado en 2010

Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion

artículo científico publicado en 2011

Binding of aldolase and glyceraldehyde-3-phosphate dehydrogenase to the cytoplasmic tails of Plasmodium falciparum merozoite duffy binding-like and reticulocyte homology ligands

artículo científico publicado en 2012

Broadly reactive antibodies specific for Plasmodium falciparum MSP-1(19) are associated with the protection of naturally exposed children against infection

artículo científico publicado en 2012

Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya

artículo científico publicado en 2009

Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii

artículo científico publicado en 2003

Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure

artículo científico publicado en 2008

Codon optimization of gene fragments encoding Plasmodium falciparum merzoite proteins enhances DNA vaccine protein expression and immunogenicity in mice.

artículo científico publicado en 2001

Conjugating recombinant proteins to Pseudomonas aeruginosa ExoProtein A: a strategy for enhancing immunogenicity of malaria vaccine candidates

artículo científico publicado en 2007

Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort

artículo científico publicado en 2015

Corrigendum to “Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer” [Vaccine 30 (2012) 189–194]

scholarly article by Daming Zhu et al published May 2013 in Vaccine

Decrease in Numbers of Naive and Resting B Cells in HIV-Infected Kenyan Adults Leads to a Proportional Increase in Total and Plasmodium falciparum-Specific Atypical Memory B Cells

artículo científico publicado en 2017

Delineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodies

artículo científico publicado en 2011

Determination of protein concentration for protein-protein conjugates using ultraviolet absorption

artículo científico publicado en 2012

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle

artículo científico publicado en 2013

Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites.

artículo científico publicado en 1994

Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance

artículo científico publicado en 2016

Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion

artículo científico publicado en 2013

Effect of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali

artículo científico publicado en 2017

Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer

artículo científico publicado en 2011

Endostatin binds tropomyosin. A potential modulator of the antitumor activity of endostatin.

artículo científico publicado en 2001

Estimation of recent and long-term malaria transmission in a population by antibody testing to multiple Plasmodium falciparum antigens

artículo científico publicado en 2014

Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA.

artículo científico publicado en 2008

Ex vivo cytokine and memory T cell responses to the 42-kDa fragment of Plasmodium falciparum merozoite surface protein-1 in vaccinated volunteers

artículo científico publicado en 2008

Identification and characterization of the Plasmodium yoelii PyP140/RON4 protein, an orthologue of Toxoplasma gondii RON4, whose cysteine-rich domain does not protect against lethal parasite challenge infection

artículo científico publicado en 2008

Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development

artículo científico publicado en 2013

Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assay

artículo científico publicado en 2013

Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide Display

artículo científico publicado en 2015

Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes

artículo científico publicado en 2010

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

artículo científico publicado en 2014

Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM blood-stage infection

artículo científico publicado en 2000

Immunogenicity of self-associated aggregates and chemically cross-linked conjugates of the 42 kDa Plasmodium falciparum merozoite surface protein-1

artículo científico publicado en 2012

Ion-exchange—immunoaffinity purification of a recombinant baculovirus Plasmodium falciparum apical membrane antigen, PF83/AMA-1

artículo científico publicado en 1993

Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25.

artículo científico publicado en 2006

Low prevalence of antibodies to preerythrocytic but not blood-stage Plasmodium falciparum antigens in an area of unstable malaria transmission compared to prevalence in an area of stable malaria transmission

artículo científico publicado en 2008

Malaria infection alters the expression of B-cell activating factor resulting in diminished memory antibody responses and survival

artículo científico publicado en 2012

Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques

artículo científico publicado en 2011

Maternal-foetal transfer of Plasmodium falciparum and Plasmodium vivax antibodies in a low transmission setting

artículo científico publicado en 2016

Molecular characterisation of Plasmodium reichenowi apical membrane antigen-1 (AMA-1), comparison with P. falciparum AMA-1, and antibody-mediated inhibition of red cell invasion.

artículo científico publicado en 2000

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity.

artículo científico publicado en 2018

NOS2 variants reveal a dual genetic control of nitric oxide levels, susceptibility to Plasmodium infection, and cerebral malaria

artículo científico publicado en 2013

New insights into acquisition, boosting, and longevity of immunity to malaria in pregnant women

artículo científico publicado en 2012

Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in Pichia pastoris

artículo científico publicado en 2009

Overcoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1.

artículo científico publicado en 2013

Particle-based platforms for malaria vaccines

artículo científico publicado en 2015

Passive immunization with a multicomponent vaccine against conserved domains of apical membrane antigen 1 and 235-kilodalton rhoptry proteins protects mice against Plasmodium yoelii blood-stage challenge infection. ⬇️

artículo científico publicado en 2006

Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria

artículo científico publicado en 2012

Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria

artículo científico publicado en 2007

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

artículo científico publicado en 2008

Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults

artículo científico publicado en 2010

Plasmodium berghei ookinete densities in three anopheline species

artículo científico publicado en 1991

Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P

artículo científico publicado en 2012

Precise Timing of Expression of a Plasmodium falciparum- derived Transgene in Plasmodium berghei Is a Critical Determinant of Subsequent Subcellular Localization ⬇️

artículo científico publicado el 12 de junio de 1998

Production and characterization of clinical grade Escherichia coli derived Plasmodium falciparum 42 kDa merozoite surface protein 1 (MSP1(42)) in the absence of an affinity tag.

artículo científico publicado en 2006

Protection of Aotus monkeys by Plasmodium falciparum EBA-175 region II DNA prime-protein boost immunization regimen

artículo científico publicado en 2000

Protein-Specific Features Associated with Variability in Human Antibody Responses to Plasmodium falciparum Malaria Antigens.

artículo científico publicado en 2018

Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults

artículo científico publicado en 2016

Screen-less expanded bed column: new approach for the recovery and purification of a malaria transmission blocking vaccine candidate from Pichia pastoris.

artículo científico publicado en 2006

Sequence diversity and antigenic polymorphism in the Plasmodium yoelii p235 high molecular mass rhoptry proteins and their genes

artículo científico publicado en 2001

Simplagrin, a platelet aggregation inhibitor from Simulium nigrimanum salivary glands specifically binds to the Von Willebrand factor receptor in collagen and inhibits carotid thrombus formation in vivo

artículo científico publicado en 2014

Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230.

artículo científico publicado en 2016

Structural and immunological analysis of anthrax recombinant protective antigen adsorbed to aluminum hydroxide adjuvant.

artículo científico publicado en 2012

Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins

scientific article published on 24 July 2020

Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate

artículo científico publicado en 2009

TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.

artículo científico publicado en 2018

The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections

artículo científico publicado en 2010

The Regulation of Inherently Autoreactive VH4-34-Expressing B Cells in Individuals Living in a Malaria-Endemic Area of West Africa.

artículo científico publicado en 2016

The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals

artículo científico publicado en 2009

The epitope of monoclonal antibodies blocking erythrocyte invasion by Plasmodium falciparum map to the dimerization and receptor glycan binding sites of EBA-175. ⬇️

artículo científico publicado en 2013

VAR2CSA Domain-Specific Analysis of Naturally Acquired Functional Antibodies to Plasmodium falciparum Placental Malaria

artículo científico publicado en 2016

Lista de obras de David L. Narum

A Method for Producing Protein Nanoparticles with Applications in Vaccines

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection

A novel Plasmodium falciparum erythrocyte binding protein-2 (EBP2/BAEBL) involved in erythrocyte receptor binding

A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

A recombinant baculovirus-expressed Plasmodium falciparum receptor-binding domain of erythrocyte binding protein EBA-175 biologically mimics native protein. ⬇️

Absence of antigenic competition in Aotus monkeys immunized with Plasmodium falciparum DNA vaccines delivered as a mixture

Accelerated and long term stability study of Pfs25-EPA conjugates adjuvanted with Alhydrogel®.

Addition of CpG ODN to recombinant Pseudomonas aeruginosa ExoProtein A conjugates of AMA1 and Pfs25 greatly increases the number of responders

Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo

Analysis of the conformation and function of the Plasmodium falciparum merozoite proteins MTRAP and PTRAMP

Analysis of the processing of Plasmodium falciparum rhoptry-associated protein 1 and localization of Pr86 to schizont rhoptries and p67 to free merozoites

Antibodies against the Plasmodium falciparum receptor binding domain of EBA-175 block invasion pathways that do not involve sialic acids ⬇️

Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic

Antibodies to Plasmodium falciparum antigens vary by age and antigen in children in a malaria-holoendemic area of Kenya

Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malaria

Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemia

Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion

Binding of aldolase and glyceraldehyde-3-phosphate dehydrogenase to the cytoplasmic tails of Plasmodium falciparum merozoite duffy binding-like and reticulocyte homology ligands

Broadly reactive antibodies specific for Plasmodium falciparum MSP-1(19) are associated with the protection of naturally exposed children against infection

Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya

Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii

Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure

Codon optimization of gene fragments encoding Plasmodium falciparum merzoite proteins enhances DNA vaccine protein expression and immunogenicity in mice.

Conjugating recombinant proteins to Pseudomonas aeruginosa ExoProtein A: a strategy for enhancing immunogenicity of malaria vaccine candidates

Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort

Corrigendum to “Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer” [Vaccine 30 (2012) 189–194]

Decrease in Numbers of Naive and Resting B Cells in HIV-Infected Kenyan Adults Leads to a Proportional Increase in Total and Plasmodium falciparum-Specific Atypical Memory B Cells

Delineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodies

Determination of protein concentration for protein-protein conjugates using ultraviolet absorption

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle

Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites.

Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance

Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion

Effect of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali

Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer

Endostatin binds tropomyosin. A potential modulator of the antitumor activity of endostatin.

Estimation of recent and long-term malaria transmission in a population by antibody testing to multiple Plasmodium falciparum antigens

Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA.

Ex vivo cytokine and memory T cell responses to the 42-kDa fragment of Plasmodium falciparum merozoite surface protein-1 in vaccinated volunteers

Identification and characterization of the Plasmodium yoelii PyP140/RON4 protein, an orthologue of Toxoplasma gondii RON4, whose cysteine-rich domain does not protect against lethal parasite challenge infection

Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development

Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assay

Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide Display

Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM blood-stage infection

Immunogenicity of self-associated aggregates and chemically cross-linked conjugates of the 42 kDa Plasmodium falciparum merozoite surface protein-1

Ion-exchange—immunoaffinity purification of a recombinant baculovirus Plasmodium falciparum apical membrane antigen, PF83/AMA-1

Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25.

Low prevalence of antibodies to preerythrocytic but not blood-stage Plasmodium falciparum antigens in an area of unstable malaria transmission compared to prevalence in an area of stable malaria transmission

Malaria infection alters the expression of B-cell activating factor resulting in diminished memory antibody responses and survival

Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques

Maternal-foetal transfer of Plasmodium falciparum and Plasmodium vivax antibodies in a low transmission setting

Molecular characterisation of Plasmodium reichenowi apical membrane antigen-1 (AMA-1), comparison with P. falciparum AMA-1, and antibody-mediated inhibition of red cell invasion.

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity.

NOS2 variants reveal a dual genetic control of nitric oxide levels, susceptibility to Plasmodium infection, and cerebral malaria

New insights into acquisition, boosting, and longevity of immunity to malaria in pregnant women

Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in Pichia pastoris

Overcoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1.

Particle-based platforms for malaria vaccines

Passive immunization with a multicomponent vaccine against conserved domains of apical membrane antigen 1 and 235-kilodalton rhoptry proteins protects mice against Plasmodium yoelii blood-stage challenge infection. ⬇️

Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria

Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults

Plasmodium berghei ookinete densities in three anopheline species

Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P

Precise Timing of Expression of a Plasmodium falciparum- derived Transgene in Plasmodium berghei Is a Critical Determinant of Subsequent Subcellular Localization ⬇️

Production and characterization of clinical grade Escherichia coli derived Plasmodium falciparum 42 kDa merozoite surface protein 1 (MSP1(42)) in the absence of an affinity tag.

Protection of Aotus monkeys by Plasmodium falciparum EBA-175 region II DNA prime-protein boost immunization regimen

Protein-Specific Features Associated with Variability in Human Antibody Responses to Plasmodium falciparum Malaria Antigens.

Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults

Screen-less expanded bed column: new approach for the recovery and purification of a malaria transmission blocking vaccine candidate from Pichia pastoris.

Sequence diversity and antigenic polymorphism in the Plasmodium yoelii p235 high molecular mass rhoptry proteins and their genes

Simplagrin, a platelet aggregation inhibitor from Simulium nigrimanum salivary glands specifically binds to the Von Willebrand factor receptor in collagen and inhibits carotid thrombus formation in vivo

Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230.

Structural and immunological analysis of anthrax recombinant protective antigen adsorbed to aluminum hydroxide adjuvant.

Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins