Lista de obras - Michael Brines - Dominio Público Uruguay

A Nonhematopoietic Erythropoietin Analogue, ARA 290, Inhibits Macrophage Activation and Prevents Damage to Transplanted Islets.

artículo científico publicado en 2015

A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema

artículo científico publicado en 2020

A nonerythropoietic peptide that mimics the 3D structure of erythropoietin reduces organ injury/dysfunction and inflammation in experimental hemorrhagic shock.

artículo científico publicado en 2011

A small nonerythropoietic helix B surface peptide based upon erythropoietin structure is cardioprotective against ischemic myocardial damage.

artículo científico publicado en 2010

ARA 290 for treatment of small fiber neuropathy in sarcoidosis.

artículo científico publicado en 2014

ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density

artículo científico publicado en 2013

ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes.

artículo científico publicado en 2014

ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response

artículo científico publicado en 2014

ARA290, a Specific Agonist of Erythropoietin/CD131 Heteroreceptor, Improves Circulating Endothelial Progenitors' Angiogenic Potential and Homing Ability.

artículo científico publicado en 2016

ARA290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain: an experimental study in rats and β-common receptor knockout mice.

artículo científico publicado en 2011

Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivative

artículo científico publicado en 2006

An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness.

artículo científico publicado en 2000

Anthropometric variables accurately predict dual energy x-ray absorptiometric-derived body composition and can be used to screen for diabetes

artículo científico publicado en 2011

Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.

artículo científico publicado en 2003

Bees have rules

scientific article published on 01 November 1979

Behavioral method for the treatment of idiopathic scoliosis.

artículo científico publicado en 1985

Cell-type specific expression of Na+, K(+)-ATPase catalytic subunits in cultured neurons and glia: evidence for polarized distribution in neurons

scientific article published on 01 December 1993

Characterization of canine renal receptors for the parathyroid hormone-like protein associated with humoral hypercalcemia of malignancy

artículo científico publicado en 1989

Chronic administration of small nonerythropoietic peptide sequence of erythropoietin effectively ameliorates the progression of postmyocardial infarction-dilated cardiomyopathy

artículo científico publicado en 2013

Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis

artículo científico publicado en 2017

Clinical case seminar: Cushing's syndrome in an elderly woman with large thyroid and pituitary masses

artículo científico publicado en 1996

Cornea nerve fiber quantification and construction of phenotypes in patients with fibromyalgia.

artículo científico publicado en 2016

Corneal nerve fiber size adds utility to the diagnosis and assessment of therapeutic response in patients with small fiber neuropathy.

artículo científico publicado en 2018

Cytoarchitectural relationships between [3H]ouabain binding and mRNA for isoforms of the sodium pump catalytic subunit in rat brain.

artículo científico publicado en 1991

Cytoprotective doses of erythropoietin or carbamylated erythropoietin have markedly different procoagulant and vasoactive activities.

artículo científico publicado en 2006

Discovery of a master regulator of injury and healing: tipping the outcome from damage toward repair.

artículo científico publicado en 2014

Dynamic patterns of skylight polarization as clock and compass.

artículo científico publicado en 1980

Dynorphin and the kappa 1 ligand [3H]U69,593 binding in the human epileptogenic hippocampus ⬇️

artículo científico publicado el 1 de octubre de 1997

Effect of insulin and an erythropoietin-derived peptide (ARA290) on established neuritic dystrophy and neuronopathy in Akita (Ins2 Akita) diabetic mouse sympathetic ganglia.

artículo científico publicado en 2011

Endogenous parathyroid hormone-related protein functions as a neuroprotective agent.

artículo científico publicado en 2002

Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury.

artículo científico publicado en 2002

Erythropoietin and engineered innate repair activators.

artículo científico publicado en 2013

Erythropoietin and erythropoietin receptor expression after experimental spinal cord injury encourages therapy by exogenous erythropoietin

artículo científico publicado en 2005

Erythropoietin as a tissue-protective cytokine in brain injury: what do we know and where do we go?

artículo científico publicado en 2004

Erythropoietin as an antiapoptotic, tissue-protective cytokine.

artículo científico publicado en 2004

Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor.

artículo científico publicado en 2013

Erythropoietin both protects from and reverses experimental diabetic neuropathy

artículo científico publicado en 2004

Erythropoietin is a multifunctional tissue-protective cytokine ⬇️

artículo científico publicado el 1 de noviembre de 2003

Erythropoietin modulation of astrocyte water permeability as a component of neuroprotection

scholarly article

Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury

artículo científico publicado en 2002

Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress

artículo científico publicado en 2001

Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis

artículo científico publicado en 2003

Erythropoietin therapy for acute stroke is both safe and beneficial

artículo científico publicado en 2002

Erythropoietin, modified to not stimulate red blood cell production, retains its cardioprotective properties.

artículo científico publicado en 2005

Erythropoietin: not just about erythropoiesis

artículo científico publicado en 2010

Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin

artículo científico publicado en 2015

Glutamate receptor subunits GluR1 and GluR2/3 distribution shows reorganization in the human epileptogenic hippocampus.

artículo científico publicado en 1998

Glutamate up-regulates alpha 1 and alpha 2 subunits of the sodium pump in astrocytes of mixed telencephalic cultures but not in pure astrocyte cultures

scientific article published on 01 December 1993

Increased expression of erythropoietin receptor on blood vessels in the human epileptogenic hippocampus with sclerosis

scientific article published on 01 January 2004

Inhibition of alpha 2/alpha 3 sodium pump isoforms potentiates glutamate neurotoxicity

artículo científico publicado el 18 de septiembre de 1992

Ketamine does not produce relief of neuropathic pain in mice lacking the β-common receptor (CD131).

artículo científico publicado en 2013

Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury.

artículo científico publicado en 2005

Neurochemical remodelling of the hippocampus in human temporal lobe epilepsy.

artículo científico publicado en 1992

Neuroprotective properties of epoetin alfa.

artículo científico publicado en 2002

Neurotransmitters and their receptors in human temporal lobe epilepsy

artículo científico publicado el 1 de enero de 1992

Nonerythropoietic tissue protective compounds are highly effective facilitators of wound healing.

artículo científico publicado en 2009

Parathyroid hormone modulates angiotensin II-induced aldosterone secretion from the adrenal glomerulosa cell

scientific article published on 01 July 1991

Parathyroid hormone-related protein markedly potentiates depolarization-induced catecholamine release in PC12 cells via L-type voltage-sensitive Ca2+ channels

scientific article published on 01 February 1999

Parathyroid hormone-related protein protects against kainic acid excitotoxicity in rat cerebellar granule cells by regulating L-type channel calcium flux

scientific article published on 01 October 1999

Promises and pitfalls in erythopoietin-mediated tissue protection: are nonerythropoietic derivatives a way forward?

artículo científico publicado en 2011

Protective Effect of Erythropoietin and Its Carbamylated Derivative in Experimental Cisplatin Peripheral Neurotoxicity

scientific article published on 01 April 2006

Quantitative Autoradiographic Analysis of lonotropic Glutamate Receptor Subtypes in Human Temporal Lobe Epilepsy: Up‐regulation in Reorganized Epileptogenic Hippocampus ⬇️

artículo científico publicado el 1 de octubre de 1997

Recombinant human erythropoietin for neuroprotection: what is the evidence?

artículo científico publicado en 2002

Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling

artículo científico publicado en 2003

Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives

artículo científico publicado en 2006

Regional distributions of hippocampal Na+,K(+)-ATPase, cytochrome oxidase, and total protein in temporal lobe epilepsy

scientific article published on 01 April 1995

Reply to Abdelwahid and Smith: The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin.

artículo científico publicado en 2011

Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study

artículo científico publicado en 2012

Suppression of coronary atherosclerosis by helix B surface Peptide, a nonerythropoietic, tissue-protective compound derived from erythropoietin.

artículo científico publicado en 2013

TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury

artículo científico publicado en 2008

The A2 isoform of rat Na+,K(+)-adenosine triphosphatase is active and exhibits high ouabain affinity when expressed in transfected fibroblasts

artículo científico publicado el 1 de junio de 1992

The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase ⬇️

artículo científico publicado el 1 de enero de 1992

The cardiac glycoside ouabain potentiates excitotoxic injury of adult neurons in rat hippocampus

scientific article published on 01 May 1995

The mast cell plays a central role in the immune system of teleost fish

artículo científico

The therapeutic potential of erythropoiesis-stimulating agents for tissue protection: a tale of two receptors.

scientific article published on 08 January 2010

Thyrotropin-secreting adenoma in an adolescent girl without increased serum thyrotropin-alpha

artículo científico publicado en 1994

Transcripts of the transposon mariner are present in epileptic brain.

artículo científico publicado en 1998

Vasoactive intestinal polypeptide and its receptor changes in human temporal lobe epilepsy

artículo científico publicado en 1995

Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.

artículo científico publicado en 1994

What evidence supports use of erythropoietin as a novel neurotherapeutic?

artículo científico publicado en 2002

Lista de obras de Michael Brines

A Nonhematopoietic Erythropoietin Analogue, ARA 290, Inhibits Macrophage Activation and Prevents Damage to Transplanted Islets.

A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema

A nonerythropoietic peptide that mimics the 3D structure of erythropoietin reduces organ injury/dysfunction and inflammation in experimental hemorrhagic shock.

A small nonerythropoietic helix B surface peptide based upon erythropoietin structure is cardioprotective against ischemic myocardial damage.

ARA 290 for treatment of small fiber neuropathy in sarcoidosis.

ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density

ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes.

ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response

ARA290, a Specific Agonist of Erythropoietin/CD131 Heteroreceptor, Improves Circulating Endothelial Progenitors' Angiogenic Potential and Homing Ability.

ARA290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain: an experimental study in rats and β-common receptor knockout mice.

Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivative

An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness.

Anthropometric variables accurately predict dual energy x-ray absorptiometric-derived body composition and can be used to screen for diabetes

Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.

Bees have rules

Behavioral method for the treatment of idiopathic scoliosis.

Cell-type specific expression of Na+, K(+)-ATPase catalytic subunits in cultured neurons and glia: evidence for polarized distribution in neurons

Characterization of canine renal receptors for the parathyroid hormone-like protein associated with humoral hypercalcemia of malignancy

Chronic administration of small nonerythropoietic peptide sequence of erythropoietin effectively ameliorates the progression of postmyocardial infarction-dilated cardiomyopathy

Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis

Clinical case seminar: Cushing's syndrome in an elderly woman with large thyroid and pituitary masses

Cornea nerve fiber quantification and construction of phenotypes in patients with fibromyalgia.

Corneal nerve fiber size adds utility to the diagnosis and assessment of therapeutic response in patients with small fiber neuropathy.

Cytoarchitectural relationships between [3H]ouabain binding and mRNA for isoforms of the sodium pump catalytic subunit in rat brain.

Cytoprotective doses of erythropoietin or carbamylated erythropoietin have markedly different procoagulant and vasoactive activities.

Discovery of a master regulator of injury and healing: tipping the outcome from damage toward repair.

Dynamic patterns of skylight polarization as clock and compass.

Dynorphin and the kappa 1 ligand [3H]U69,593 binding in the human epileptogenic hippocampus ⬇️

Effect of insulin and an erythropoietin-derived peptide (ARA290) on established neuritic dystrophy and neuronopathy in Akita (Ins2 Akita) diabetic mouse sympathetic ganglia.

Endogenous parathyroid hormone-related protein functions as a neuroprotective agent.

Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury.

Erythropoietin and engineered innate repair activators.

Erythropoietin and erythropoietin receptor expression after experimental spinal cord injury encourages therapy by exogenous erythropoietin

Erythropoietin as a tissue-protective cytokine in brain injury: what do we know and where do we go?

Erythropoietin as an antiapoptotic, tissue-protective cytokine.

Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor.

Erythropoietin both protects from and reverses experimental diabetic neuropathy

Erythropoietin is a multifunctional tissue-protective cytokine ⬇️

Erythropoietin modulation of astrocyte water permeability as a component of neuroprotection

Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury

Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress

Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis

Erythropoietin therapy for acute stroke is both safe and beneficial

Erythropoietin, modified to not stimulate red blood cell production, retains its cardioprotective properties.

Erythropoietin: not just about erythropoiesis

Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin

Glutamate receptor subunits GluR1 and GluR2/3 distribution shows reorganization in the human epileptogenic hippocampus.

Glutamate up-regulates alpha 1 and alpha 2 subunits of the sodium pump in astrocytes of mixed telencephalic cultures but not in pure astrocyte cultures

Increased expression of erythropoietin receptor on blood vessels in the human epileptogenic hippocampus with sclerosis

Inhibition of alpha 2/alpha 3 sodium pump isoforms potentiates glutamate neurotoxicity

Ketamine does not produce relief of neuropathic pain in mice lacking the β-common receptor (CD131).

Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury.

Neurochemical remodelling of the hippocampus in human temporal lobe epilepsy.

Neuroprotective properties of epoetin alfa.

Neurotransmitters and their receptors in human temporal lobe epilepsy

Nonerythropoietic tissue protective compounds are highly effective facilitators of wound healing.

Parathyroid hormone modulates angiotensin II-induced aldosterone secretion from the adrenal glomerulosa cell

Parathyroid hormone-related protein markedly potentiates depolarization-induced catecholamine release in PC12 cells via L-type voltage-sensitive Ca2+ channels

Parathyroid hormone-related protein protects against kainic acid excitotoxicity in rat cerebellar granule cells by regulating L-type channel calcium flux

Promises and pitfalls in erythopoietin-mediated tissue protection: are nonerythropoietic derivatives a way forward?

Protective Effect of Erythropoietin and Its Carbamylated Derivative in Experimental Cisplatin Peripheral Neurotoxicity

Quantitative Autoradiographic Analysis of lonotropic Glutamate Receptor Subtypes in Human Temporal Lobe Epilepsy: Up‐regulation in Reorganized Epileptogenic Hippocampus ⬇️

Recombinant human erythropoietin for neuroprotection: what is the evidence?

Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling

Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives

Regional distributions of hippocampal Na+,K(+)-ATPase, cytochrome oxidase, and total protein in temporal lobe epilepsy

Reply to Abdelwahid and Smith: The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin.

Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study

Suppression of coronary atherosclerosis by helix B surface Peptide, a nonerythropoietic, tissue-protective compound derived from erythropoietin.

TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury

The A2 isoform of rat Na+,K(+)-adenosine triphosphatase is active and exhibits high ouabain affinity when expressed in transfected fibroblasts

The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase ⬇️

The cardiac glycoside ouabain potentiates excitotoxic injury of adult neurons in rat hippocampus

The mast cell plays a central role in the immune system of teleost fish

The therapeutic potential of erythropoiesis-stimulating agents for tissue protection: a tale of two receptors.

Thyrotropin-secreting adenoma in an adolescent girl without increased serum thyrotropin-alpha

Transcripts of the transposon mariner are present in epileptic brain.

Vasoactive intestinal polypeptide and its receptor changes in human temporal lobe epilepsy

Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.