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Lista de obras de Renu Wadhwa

2,3-Dihydro-3β-methoxy Withaferin-A Protects Normal Cells against Stress: Molecular Evidence of Its Potent Cytoprotective Activity

artículo científico publicado en 2017

A Novel Alternatively Spliced Form of Murine Vascular Endothelial Growth Factor, VEGF 115

artículo científico publicado el 30 de enero de 1998

A novel putative collaborator of p19ARF

artículo científico publicado en 2003

A novel testis-specific metallothionein-like protein, tesmin, is an early marker of male germ cell differentiation

artículo científico publicado en 1999

Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides.

artículo científico publicado en 2005

Addressing Challenges to Enhance the Bioactives of Withania somnifera through Organ, Tissue, and Cell Culture Based Approaches.

artículo científico publicado en 2017

Alternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback control

artículo científico publicado en 2004

An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where?

artículo científico publicado en 2002

An antibody-conjugated internalizing quantum dot suitable for long-term live imaging of cells

artículo científico publicado en 2007

Anticancer Activity in Honeybee Propolis: Functional Insights to the Role of Caffeic Acid Phenethyl Ester and Its Complex With γ-Cyclodextrin.

artículo científico publicado en 2018

Anticancer activity of the supercritical extract of Brazilian green propolis and its active component, artepillin C: Bioinformatics and experimental analyses of its mechanisms of action.

artículo científico publicado en 2018

Ashwagandha Leaf Derived Withanone Protects Normal Human Cells Against the Toxicity of Methoxyacetic Acid, a Major Industrial Metabolite

artículo científico publicado el 4 de mayo de 2011

Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity

artículo científico publicado en 2012

Bioinformatics and Molecular Insights to Anti-Metastasis Activity of Triethylene Glycol Derivatives

artículo científico publicado en 2020

Biotechnological interventions in Withania somnifera (L.) Dunal

artículo científico

CARF (Collaborator of ARF) overexpression in p53-deficient cells promotes carcinogenesis

artículo científico publicado en 2015

CARF Is a vital dual regulator of cellular senescence and apoptosis

scientific article published on 10 November 2008

CARF binds to three members (ARF, p53, and HDM2) of the p53 tumor-suppressor pathway.

artículo científico publicado en 2007

CARF enrichment promotes epithelial-mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target.

artículo científico publicado en 2018

CARF is a multi-module regulator of cell proliferation and a molecular bridge between cellular senescence and carcinogenesis.

artículo científico publicado en 2017

CARF: an emerging regulator of p53 tumor suppressor and senescence pathway.

artículo científico publicado en 2008

Caffeic acid phenethyl ester (CAPE) possesses pro-hypoxia and anti-stress activities: bioinformatics and experimental evidences.

artículo científico publicado en 2018

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.

artículo científico publicado en 2009

Cell migration and metastasis as targets of small RNA-based molecular genetic analyses.

artículo científico publicado en 2004

Circulating mortalin autoantibody--a new serological marker of liver cirrhosis

artículo científico publicado en 2015

Cloning and characterization of a novel gene, striamin, that interacts with the tumor suppressor protein p53

scientific journal article

Collaborator of ARF (CARF) regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling

artículo científico publicado en 2014

Combinations of Ashwagandha leaf extracts protect brain-derived cells against oxidative stress and induce differentiation

artículo científico publicado en 2015

Correlation between complementation group for immortality and the cellular distribution of mortalin.

artículo científico publicado en 1995

Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review).

artículo científico publicado en 2017

Deceleration of senescence in normal human fibroblasts by withanone extracted from ashwagandha leaves.

artículo científico publicado en 2009

Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1.

artículo científico publicado en 1997

Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences

artículo científico publicado en 2012

Differential subcellular distribution of mortalin in mortal and immortal mouse and human fibroblasts.

artículo científico publicado en 1993

Editorial: special issue of Biogerontology on brain aging.

artículo científico publicado en 2008

Effect of Ashwagandha Withanolides on Muscle Cell Differentiation

artículo científico publicado en 2021

Effect of sodium hypophosphite feeding on adenosine triphosphatase activity in ageing Zaprionus paravittiger (Diptera).

artículo científico publicado en 1989

Effect of sodium selenite on antioxidative enzymes of banana fruitfly

artículo científico publicado en 1989

Elevated levels of mortalin expression in human brain tumors.

artículo científico publicado en 1997

Embelin inhibits TNF-α converting enzyme and cancer cell metastasis: molecular dynamics and experimental evidence

artículo científico publicado en 2014

Enhanced expression of multiple forms of VEGF is associated with spontaneous immortalization of murine fibroblasts.

artículo científico publicado en 1994

Evaluation and selection of candidate reference genes for normalization of quantitative RT-PCR in Withania somnifera (L.) Dunal

artículo científico publicado en 2015

Evaluation of the anti-proliferative and anti-oxidative activities of leaf extract from in vivo and in vitro raised Ashwagandha.

artículo científico publicado en 2004

Expression analysis of mortalin, a unique member of the Hsp70 family of proteins, in rat tissues.

artículo científico publicado en 1997

Expression of noncoding vault RNA in human malignant cells and its importance in mitoxantrone resistance

artículo científico publicado en 2010

Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75.

artículo científico publicado en 2002

Fate of bone marrow mesenchymal stem cells following the allogeneic transplantation of cartilaginous aggregates into osteochondral defects of rabbits.

artículo científico publicado en 2010

Fate of bone marrow mesenchymal stromal cells following autologous transplantation in a rabbit model of osteonecrosis.

artículo científico publicado en 2016

Functional Characterisation of Anticancer Activity in the Aqueous Extract of Helicteres angustifolia L. Roots

artículo científico publicado en 2016

Functional significance of minor structural and expression changes in stress chaperone mortalin.

artículo científico publicado en 2007

Functional significance of point mutations in stress chaperone mortalin and their relevance to Parkinson disease.

artículo científico publicado en 2015

Genetic differences between the pancytosolic and perinuclear forms of murine mortalin.

artículo científico publicado en 1996

Geroprotection by glycerol: insights to its mechanisms and clinical potentials.

artículo científico publicado en 2006

Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan

artículo científico publicado en 2000

Heterogeneous nuclear ribonucleoprotein K (hnRNP-K) promotes tumor metastasis by induction of genes involved in extracellular matrix, cell movement, and angiogenesis.

artículo científico publicado en 2013

Identification and characterization of molecular interactions between glucose-regulated proteins (GRPs) mortalin/GRP75/peptide-binding protein 74 (PBP74) and GRP94.

artículo científico publicado en 2001

Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60.

artículo científico publicado en 2005

Identification and functional characterization of nuclear mortalin in human carcinogenesis.

artículo científico publicado en 2014

Identification of genetic events involved in early steps of immortalization of mouse fibroblasts.

artículo científico publicado en 1994

Imminent approaches towards molecular interventions in ageing.

artículo científico publicado en 2004

Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member.

artículo científico publicado en 1998

Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin.

artículo científico publicado en 2011

Induction of senescence in cancer cells by 5'-Aza-2'-deoxycytidine: Bioinformatics and experimental insights to its targets

artículo científico

Internalizing antibody-based targeted gene delivery for human cancer cells.

artículo científico publicado en 2007

Involvement of hippocampal Arc in amnesia and its recovery by alcoholic extract of Ashwagandha leaves

artículo científico publicado en 2013

Life span studies in Zaprionus paravittiger with sodium hypophosphite feeding.

artículo científico publicado en 1986

Limited capacity of the nuclear matrix to bind telomere repeat binding factor TRF1 may restrict the proliferation of mortal human fibroblasts

artículo científico publicado en 2003

Loss-of-function screening by randomized intracellular antibodies: identification of hnRNP-K as a potential target for metastasis

artículo científico publicado en 2007

Loss-of-function screening to identify miRNAs involved in senescence: tumor suppressor activity of miRNA-335 and its new target CARF.

scientific article published on 26 July 2016

Low Dose of Fluoride in the Culture Medium of Cordyceps militaris Promotes Its Growth and Enhances Bioactives with Antioxidant and Anticancer Properties

artículo científico publicado en 2021

Malignant transformation of NIH3T3 cells by overexpression of mot-2 protein.

artículo científico publicado en 1998

Merger of ayurveda and tissue culture-based functional genomics: inspirations from systems biology

artículo científico publicado en 2008

MicroRNA-296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3' untranslated region

artículo científico publicado en 2011

Mimotope-hormesis and mortalin/grp75/mthsp70: a new hypothesis on how infectious disease-associated epitope mimicry may explain low cancer burden in developing nations.

artículo científico publicado en 2005

Mixtures of Three Mortaparibs with Enhanced Anticancer, Anti-Migration, and Antistress Activities: Molecular Characterization in p53-Null Cancer Cells

artículo científico publicado en 2024

Molecular Characterization and Enhancement of Anticancer Activity of Caffeic Acid Phenethyl Ester by γ Cyclodextrin

artículo científico publicado en 2016

Molecular Insights Into Withaferin-A-Induced Senescence: Bioinformatics and Experimental Evidence to the Role of NFκB and CARF

artículo científico publicado en 2019

Molecular characterization of apoptosis induced by CARF silencing in human cancer cells

artículo científico publicado en 2010

Molecular characterization of apoptosis induced by CARF silencing in human cancer cells.

artículo científico publicado en 2011

Molecular characterization of collaborator of ARF (CARF) as a DNA damage response and cell cycle checkpoint regulatory protein

artículo científico publicado en 2014

Molecular dynamics-based identification of novel natural mortalin-p53 abrogators as anticancer agents

artículo científico publicado en 2016

Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization

artículo científico publicado en 2013

Mortalin antibody-conjugated quantum dot transfer from human mesenchymal stromal cells to breast cancer cells requires cell-cell interaction

artículo científico publicado en 2013

Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids

artículo científico publicado en 2017

Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates

artículo científico publicado en 2003

Mortalin-MPD (mevalonate pyrophosphate decarboxylase) interactions and their role in control of cellular proliferation

artículo científico publicado en 2003

Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy

artículo científico publicado en 2011

Mortalin: present and prospective

artículo científico publicado en 2002

Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts.

artículo científico

Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells

artículo científico publicado en 2020

Novel Methods to Generate Active Ingredients-Enriched Ashwagandha Leaves and Extracts

artículo científico publicado en 2016

On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60.

artículo científico publicado en 2006

On the cytosolic and perinuclear mortalin: an insight by heat shock.

artículo científico publicado en 1993

Organic cultivation of Ashwagandha with improved biomass and high content of active Withanolides: Use of Vermicompost.

artículo científico publicado en 2018

Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts

artículo científico publicado en 2003

Phosphatidylserine Exposed Lipid Bilayer Models for Understanding Cancer Cell Selectivity of Natural Compounds: A Molecular Dynamics Simulation Study

artículo científico publicado en 2022

Preincubation with the proteasome inhibitor MG-132 enhances proteasome activity via the Nrf2 transcription factor in aging human skin fibroblasts

artículo científico publicado en 2006

Protection from aging by small chaperones: A trade-off with cancer?

artículo científico publicado en 2010

Protective Role of Ashwagandha Leaf Extract and Its Component Withanone on Scopolamine-Induced Changes in the Brain and Brain-Derived Cells

artículo científico publicado el 11 de noviembre de 2011

Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease.

artículo científico publicado en 2006

Quantum dot-based mortalin staining as a visual assay for detection of induced senescence in cancer cells

artículo científico publicado en 2007

Quantum dot-based protein imaging and functional significance of two mitochondrial chaperones in cellular senescence and carcinogenesis

artículo científico publicado en 2006

Quantum dots in bio-imaging: Revolution by the small

artículo científico publicado en 2005

Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.

artículo científico publicado en 2004

Relevance of mortalin to cancer cell stemness and cancer therapy.

scientific article published on 06 February 2017

Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling

artículo científico publicado en 2010

Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect

artículo científico publicado en 2007

Senescence and immortalization of human cells.

artículo científico publicado en 2000

Serum-free isolation and culture system to enhance the proliferation and bone regeneration of adipose tissue-derived mesenchymal stem cells

artículo científico publicado en 2015

Stable and nondisruptive in vitro/in vivo labeling of mesenchymal stem cells by internalizing quantum dots

artículo científico publicado en 2009

Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis.

artículo científico publicado en 2016

Stress chaperone mortalin regulates human melanogenesis.

artículo científico publicado en 2016

Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway.

artículo científico publicado en 2007

Structurally and functionally distinct mouse hsp70 family members Mot-1 and Mot-2 proteins are encoded by two alleles

artículo científico publicado en 2000

TAS6417, a novel epidermal growth factor receptor inhibitor targeting exon 20 insertion mutations.

artículo científico publicado en 2018

Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells

artículo científico publicado en 2015

Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes

artículo científico publicado en 2003

Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.

artículo científico publicado en 2014

The versatile stress protein mortalin as a chaperone therapeutic agent.

scientific article published on January 2009

Transcriptional inactivation of p53 by deletions and single amino acid changes in mouse mot-1 protein

scientific article published on 01 December 2000

Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction

artículo científico publicado en 2017

Tumor suppressor activity of miR-451: Identification of CARF as a new target

artículo científico publicado en 2018

Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.

artículo científico publicado en 2006

Use of a randomized hybrid ribozyme library for identification of genes involved in muscle differentiation.

artículo científico publicado en 2004

Viral ski inhibits retinoblastoma protein (Rb)-mediated transcriptional repression in a dominant negative fashion

artículo científico publicado en 1999

Water extract from the leaves of Withania somnifera protect RA differentiated C6 and IMR-32 cells against glutamate-induced excitotoxicity

artículo científico publicado en 2012

Water extract of Ashwagandha leaves has anticancer activity: identification of an active component and its mechanism of action

artículo científico publicado en 2013

Water extract of ashwagandha leaves limits proliferation and migration, and induces differentiation in glioma cells

artículo científico publicado en 2011

Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences

artículo científico publicado en 2017

Withania somnifera water extract as a potential candidate for differentiation based therapy of human neuroblastomas

artículo científico publicado en 2013

Withanone binds to mortalin and abrogates mortalin–p53 complex: Computational and experimental evidence

article

Withanone-rich combination of Ashwagandha withanolides restricts metastasis and angiogenesis through hnRNP-K.

artículo científico publicado en 2014