Lista de obras - José Antonio Rodríguez

A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K.

artículo científico publicado en 2016

A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family.

artículo científico publicado en 2012

A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis ⬇️

artículo científico publicado el 27 de junio de 2011

Absence of COCH gene mutations in patients with superior semicircular canal dehiscence

artículo científico publicado en 2011

Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis

scientific article published on 08 July 2019

BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export

artículo científico publicado en 2002

Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460.

artículo científico publicado en 2007

CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin

artículo científico publicado en 2002

Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.

artículo científico publicado en 2004

Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.

artículo científico publicado en 2008

Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia

artículo científico publicado en 2017

Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain.

artículo científico publicado en 2004

Definition of a region of loss of heterozygosity at chromosome 11q in cervical carcinoma

artículo científico publicado en 1999

Description of USP12 nuclear export sequence

artículo científico publicado en 2016

Detailed Dissection of UBE3A-Mediated DDI1 Ubiquitination

artículo científico publicado en 2019

E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes

artículo científico publicado en 2013

Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.

artículo científico publicado en 2006

Enhancing prediction of short linear protein motifs with Wregex 3.0

artículo científico publicado en 2024

Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study

artículo científico publicado en 2006

Expression and localization of inhibitor of apoptosis proteins in normal human tissues

artículo científico publicado en 2005

Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients

artículo científico publicado en 2006

Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC

scientific article published on 01 March 2008

Global histone modifications predict prognosis of resected non small-cell lung cancer.

artículo científico publicado en 2007

Homodimerization antagonizes nuclear export of survivin

artículo científico publicado en 2007

Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.

artículo científico publicado en 2005

Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies

artículo científico publicado en 2007

Immunohistochemical expression of mdm2 and p21WAF1 in invasive cervical cancer: correlation with p53 protein and high risk HPV infection

artículo científico publicado en 1998

Interplay between nuclear transport and ubiquitin/SUMO modifications in the regulation of cancer-related proteins.

artículo científico

Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.

artículo científico publicado en 2005

Keynote comment: are large-scale cancer-genomics projects ready to use?

artículo científico publicado en 2006

Leukemia-Associated Mutations in Nucleophosmin Alter Recognition by CRM1: Molecular Basis of Aberrant Transport

artículo científico publicado en 2015

Low incidence of microsatellite instability in patients with cervical carcinomas.

artículo científico publicado en 1998

Molecular Pathways: Anticancer Activity by Inhibition of Nucleocytoplasmic Shuttling

artículo científico

Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.

artículo científico publicado en 2008

Mutations in the 'Fingers' subdomain of the deubiquitinase USP1 modulate its function and activity

artículo científico publicado en 2016

Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer

scientific article published on 01 November 2004

Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.

artículo científico publicado en 2004

Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.

artículo científico publicado en 2006

Production and evaluation of alloantibodies against sheep MHC Class I antigens.

artículo científico publicado en 2004

Proteome-wide search for functional motifs altered in tumors: Prediction of nuclear export signals inactivated by cancer-related mutations

artículo científico publicado en 2016

Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.

artículo científico publicado en 2006

Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage.

artículo científico publicado en 2015

Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.

artículo científico publicado en 2003

TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

artículo científico publicado en 2006

The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma

artículo científico publicado en 2021

The nuclear protein ALY binds to and modulates the activity of transcription factor E2F2.

artículo científico publicado en 2013

Therapeutic Effects of XPO1 Inhibition in Thymic Epithelial Tumors

artículo científico publicado en 2017

Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.

artículo científico publicado en 2018

Two nuclear localization signals in USP1 mediate nuclear import of the USP1/UAF1 complex

artículo científico publicado en 2012

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy.

artículo científico

Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres

artículo científico publicado en 2006

WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus

scientific article published on 03 November 2018

Lista de obras de José Antonio Rodríguez

A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K.

A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family.

A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis ⬇️

Absence of COCH gene mutations in patients with superior semicircular canal dehiscence

Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis

BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export

Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460.

CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin

Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.

Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.

Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia

Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain.

Definition of a region of loss of heterozygosity at chromosome 11q in cervical carcinoma

Description of USP12 nuclear export sequence

Detailed Dissection of UBE3A-Mediated DDI1 Ubiquitination

E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes

Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.

Enhancing prediction of short linear protein motifs with Wregex 3.0

Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study

Expression and localization of inhibitor of apoptosis proteins in normal human tissues

Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients

Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC

Global histone modifications predict prognosis of resected non small-cell lung cancer.

Homodimerization antagonizes nuclear export of survivin

Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.

Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies

Immunohistochemical expression of mdm2 and p21WAF1 in invasive cervical cancer: correlation with p53 protein and high risk HPV infection

Interplay between nuclear transport and ubiquitin/SUMO modifications in the regulation of cancer-related proteins.

Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.

Keynote comment: are large-scale cancer-genomics projects ready to use?

Leukemia-Associated Mutations in Nucleophosmin Alter Recognition by CRM1: Molecular Basis of Aberrant Transport

Low incidence of microsatellite instability in patients with cervical carcinomas.

Molecular Pathways: Anticancer Activity by Inhibition of Nucleocytoplasmic Shuttling

Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.

Mutations in the 'Fingers' subdomain of the deubiquitinase USP1 modulate its function and activity

Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer

Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.

Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.

Production and evaluation of alloantibodies against sheep MHC Class I antigens.

Proteome-wide search for functional motifs altered in tumors: Prediction of nuclear export signals inactivated by cancer-related mutations

Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.

Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage.

Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.

TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma

The nuclear protein ALY binds to and modulates the activity of transcription factor E2F2.

Therapeutic Effects of XPO1 Inhibition in Thymic Epithelial Tumors

Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.

Two nuclear localization signals in USP1 mediate nuclear import of the USP1/UAF1 complex

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy.

Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres

WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus