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Lista de obras de Michael B. Major

A circle RNA regulatory axis promotes lung squamous metastasis via CDR1-mediated regulation of Golgi trafficking

scientific article published on 25 September 2020

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue

artículo científico publicado en 2020

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

artículo científico publicado en 2016

Approximating Isotope Distributions of Biomolecule Fragments

artículo científico publicado en 2018

BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization.

artículo científico publicado en 2014

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination

artículo científico publicado en 2013

Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53

artículo científico publicado en 2012

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

scientific article published on 08 March 2018

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

artículo científico publicado en 2018

Distinct Wnt signaling pathways have opposing roles in appendage regeneration

artículo científico

Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening.

artículo científico publicado en 2014

FAM123A Binds to Microtubules and Inhibits the Guanine Nucleotide Exchange Factor ARHGEF2 to Decrease Actomyosin Contractility ⬇️

artículo científico publicado el 4 de septiembre de 2012

FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells.

artículo científico

FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma.

artículo científico publicado en 2015

Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor

artículo científico publicado en 2020

Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo

artículo científico publicado en 2014

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

artículo científico publicado en 2016

Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus

artículo científico publicado en 2018

Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate

artículo científico publicado en 2016

Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta

artículo científico publicado en 2004

Loss of SWI/SNF chromatin remodeling alters NRF2 signaling in non-small cell lung carcinoma

scientific article published on 27 August 2020

New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening

artículo científico publicado en 2008

PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor

scientific article published on 28 September 2020

Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multi-kinase inhibition

artículo científico publicado en 2018

Receptor tyrosine kinase-like orphan receptor 2 (Ror2) expression creates a poised state of Wnt signaling in renal cancer.

artículo científico publicado en 2013

SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.

artículo científico publicado en 2014

Small-molecule synergist of the Wnt/beta-catenin signaling pathway

artículo científico publicado en 2007

Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification--mass spectrometry data.

artículo científico publicado en 2014

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase

artículo científico publicado en 2014

The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells

artículo científico publicado en 2018

The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.

artículo científico publicado en 2003

The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes

scientific article published on 14 September 2019

The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase

artículo científico publicado en 2015

USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds

artículo científico publicado en 2016

WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling

artículo científico publicado en 2012

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma ⬇️

artículo científico publicado el 18 de febrero de 2013

Wilms Tumor Gene on X Chromosome (WTX) Inhibits Degradation of NRF2 Protein through Competitive Binding to KEAP1 Protein ⬇️

artículo científico publicado el 3 de enero de 2012

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