Filtros de búsqueda

Lista de obras de Sunil R Lakhani

'Omics Approaches in Breast Cancer Research and Clinical Practice

artículo científico publicado en 2016

A Molecular and Morphological Deep-Dive Into Metaplastic Breast Cancers.

artículo científico publicado en 2019

A multimedia psychosocial support program for couples receiving infertility treatment: a feasibility study

artículo científico publicado en 2004

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

artículo científico publicado en 2005

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

artículo científico publicado en 2017

A test of performance of breast MRI interpretation in a multicentre screening study.

artículo científico publicado en 2006

Abstract 1980: Long-range regulation of HOTAIR identifies novel biomarkers of breast cancer outcome and suggests a role in genome instability

article

Abstract 32: Lynch syndrome-associated breast cancers: Clinicopathological characteristics of a case series from the Colon CFR

Abstract LB-116: Cep55, a master regulator of cytokinesis in breast cancer pathogenesis

Abstract P6-03-11: Erk5 as a therapeutic target in triple negative breast cancer (TNBC)

Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.

artículo científico publicado en 2010

Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

artículo científico publicado en 2010

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Ca

artículo científico publicado en 2017

Association analysis identifies 65 new breast cancer risk loci.

artículo científico publicado en 2017

Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p.

artículo científico publicado en 1995

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

artículo científico publicado en 2019

BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation

artículo científico publicado en 2003

Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

artículo científico publicado en 2010

Basal-like breast carcinomas: clinical outcome and response to chemotherapy

artículo científico publicado en 2006

Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival

artículo científico publicado en 2007

Bayes analysis provides evidence of pathogenicity for the BRCA1 c.135-1G>T (IVS3-1) and BRCA2 c.7977-1G>C (IVS17-1) variants displaying in vitro splicing results of equivocal clinical significance

artículo científico publicado en 2010

Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases

artículo científico publicado en 2020

Breast Cancer Brain Metastases: Clonal Evolution in Clinical Context.

artículo científico publicado en 2017

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

artículo científico publicado en 2016

Breast cancer metastasis to gynaecological organs: a clinico-pathological and molecular profiling study

Breast cancer prognostic classification in the molecular era: the role of histological grade

artículo científico publicado en 2010

Breast cancer special types: why bother?

artículo científico publicado en 2008

Breast cancer stem cells: treatment resistance and therapeutic opportunities

scientific article published on 10 February 2011

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer

artículo científico publicado en 2017

Breast pathology: beyond morphology

artículo científico publicado en 2010

CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation.

artículo científico publicado en 2001

COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment

artículo científico publicado en 2014

Can magnetic-resonance imaging help elucidate natural history of breast cancer multicentricity?

scientific article published on 01 March 1998

Can the stroma provide the clue to the cellular basis for mammographic density?

artículo científico publicado en 2003

Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient.

artículo científico publicado en 2018

Choroid plexus papillomas: immunohistochemical study

artículo científico publicado en 1990

Clinical Classification ofBRCA1andBRCA2DNA Sequence Variants: The Value of Cytokeratin Profiles and Evolutionary Analysis—A Report From the kConFab Investigators

article

Collagenous spherulosis in an adenomyoepithelioma of the breast

artículo científico publicado en 2004

Columnar cell lesions of the breast: the missing link in breast cancer progression? A morphological and molecular analysis

artículo científico publicado en 2005

Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast

artículo científico publicado en 2003

Comparative genomic hybridization analysis of myoepithelial carcinoma of the breast

artículo científico publicado en 2000

Comparative genomic hybridization reveals extensive variation among different MCF-7 cell stocks

artículo científico

Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

artículo científico publicado en 1995

Correction: In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity

artículo científico publicado en 2013

Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

artículo científico publicado en 2017

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

artículo científico publicado en 2016

Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer

artículo científico publicado en 2006

Current and future approach to the pathologist's assessment for targeted therapy in breast cancer

artículo científico publicado en 2009

Current topics in breast pathology: expert perspectives.

artículo científico publicado en 2017

Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype.

artículo científico publicado en 2004

DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

artículo científico publicado en 2010

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer

artículo científico publicado en 2017

Demystifying basal-like breast carcinomas

artículo científico publicado en 2007

Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations.

artículo científico publicado en 1996

Detection of splicing aberrations caused by BRCA1 and BRCA2 sequence variants encoding missense substitutions: implications for prediction of pathogenicity

artículo científico publicado en 2010

Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results.

artículo científico publicado en 2000

Digital spatial profiling application in breast cancer: a user's perspective

scientific article published on 26 May 2020

Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines

artículo científico publicado en 2010

Distribution and significance of 14-3-3sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue

artículo científico publicado en 2004

EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

article

Endoplasmic reticulum stress-induced death of mouse embryonic fibroblasts requires the intrinsic pathway of apoptosis.

artículo científico publicado en 2007

Environmental factors in breast cancer invasion: a mathematical modelling review

artículo científico publicado en 2017

Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer

scientific article published on 02 May 2022

Erratum: Corrigendum: Signatures of mutational processes in human cancer

artículo científico publicado en 2013

Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis

artículo científico publicado en 2013

Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study.

artículo científico publicado en 2006

Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors

artículo científico publicado en 2012

Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast

artículo científico publicado en 2004

Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer

artículo científico publicado en 2004

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

artículo científico publicado en 2006

Fibroadenoma and intraduct papilloma--a common pathogenesis?

artículo científico publicado en 2009

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

artículo científico publicado en 2015

Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay

artículo científico publicado en 2010

Genetic alterations in 'normal' luminal and myoepithelial cells of the breast

artículo científico publicado en 1999

Genetic and Histopathologic Evaluation ofBRCA1andBRCA2DNA Sequence Variants of Unknown Clinical Significance

article

Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study

artículo científico publicado en 2018

Grade of recurrent in situ and invasive carcinoma following treatment of pure ductal carcinoma in situ of the breast.

artículo científico publicado en 2004

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

artículo científico publicado en 2010

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

artículo científico publicado en 2017

Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes

artículo científico publicado en 2010

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.

artículo científico publicado en 2015

High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations

artículo científico publicado en 2016

High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers.

artículo científico publicado en 1999

How diagnosis with microarrays can help cancer patients

artículo científico publicado en 2000

Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?

artículo científico publicado en 2007

Identification of the familial cylindromatosis tumour-suppressor gene

artículo científico publicado en 2000

Improving the reproducibility of the MCF-7 cell proliferation assay for the detection of xenoestrogens

artículo científico publicado en 2000

In situ carcinoma - can we predict which patient will come back with a recurrence?

artículo científico publicado en 2007

In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity.

artículo científico publicado en 2013

In-situ lobular neoplasia: time for an awakening

artículo científico publicado en 2003

Incorporating tumour pathology information into breast cancer risk prediction algorithms

artículo científico publicado en 2010

Introduction: the role of myoepithelial cells in integration of form and function in the mammary gland

artículo científico publicado en 2005

Invasion in breast lesions: the role of the epithelial-stroma barrier

artículo científico publicado en 2017

Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics

artículo científico publicado en 2015

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

artículo científico publicado en 2014

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

artículo científico publicado en 2016

Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13

article

Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene

artículo científico publicado en 2000

Lobular carcinoma in situ: diagnostic criteria and molecular correlates

artículo científico publicado en 2020

Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry

artículo científico

Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer

artículo científico publicado en 2016

Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours.

artículo científico publicado en 2001

Loss of heterozygosity in ductal carcinoma in situ of the breast.

artículo científico publicado en 1995

Loss of heterozygosity in lobular carcinoma in situ of the breast

artículo científico publicado en 1995

Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13.

artículo científico publicado en 1995

MR imaging of the skin and nipple of the breast: differentiation between tumour recurrence and post-treatment change

artículo científico publicado en 2001

Malignant adenomyoepithelioma of the breast metastasizing to the liver

artículo científico publicado en 2003

Malignant myoepithelioma (myoepithelial carcinoma) of the breast: a detailed cytokeratin study

artículo científico publicado en 1995

Management and 5-year outcomes in 9938 women with screen-detected ductal carcinoma in situ: the UK Sloane Project

artículo científico publicado en 2018

Mapping loss of heterozygosity in normal human breast cells from BRCA1/2 carriers

artículo científico publicado en 2006

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

artículo científico publicado en 2014

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer.

artículo científico publicado en 2014

Metaplastic breast carcinomas are basal-like tumours

artículo científico publicado en 2006

Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis

artículo científico publicado en 2005

MicroRNA-182-5p targets a network of genes involved in DNA repair

artículo científico publicado en 2013

Microarray and histopathological analysis of tumours: the future and the past?

artículo científico publicado en 2001

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

artículo científico publicado en 2018

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

artículo científico publicado en 2014

Molar tooth development in caspase-3 deficient mice.

artículo científico publicado en 2006

Molecular analyses of in situ breast cancer

scientific article published on 01 November 1993

Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components

artículo científico publicado en 2000

Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis.

artículo científico publicado en 2008

Molecular aspects of breast cancer metastasis to the brain

artículo científico publicado en 2011

Molecular classification of breast cancer

artículo científico

Molecular classification of breast cancer: is it time to pack up our microscopes?

artículo científico publicado en 2011

Molecular cytogenetic comparison of apocrine hyperplasia and apocrine carcinoma of the breast

artículo científico publicado en 2001

Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes

artículo científico publicado en 2004

Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma.

artículo científico publicado en 2009

Molecular evolution of breast cancer

artículo científico publicado en 2005

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

artículo científico publicado en 2008

Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer

scientific article published on 31 March 2020

Multidimensional phenotyping of breast cancer cell lines to guide preclinical research

artículo científico publicado en 2017

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations

artículo científico publicado en 1998

Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation

artículo científico publicado en 2014

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

artículo científico publicado en 2013

Mutation analysis of five candidate genes in familial breast cancer

artículo científico publicado en 2006

Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women

artículo científico publicado en 2013

Myoepithelial cells: pathology, cell separation and markers of myoepithelial differentiation

artículo científico publicado en 2005

Natural sunscreen revealed

scientific article published on 01 December 2001

Next-Generation Sequencing of Endobronchial Ultrasound Transbronchial Needle Aspiration Specimens in Lung Cancer.

artículo científico publicado en 2017

Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study

artículo científico

Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer

artículo científico publicado en 2004

Papillary and neuroendocrine breast lesions: the WHO stance

artículo científico publicado en 2015

Pathologic quiz case: a 62-year-old woman with a 4.5-cm nodule in the right breast. Lipid-rich breast carcinoma

artículo científico publicado en 2003

Pathology of hereditary breast cancer

artículo científico publicado en 2010

Pathology of ovarian cancers in BRCA1 and BRCA2 carriers

artículo científico publicado en 2004

Phenotype-genotype correlation in familial breast cancer

artículo científico publicado en 2011

Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications

Phyllodes tumours of the breast: a consensus review

artículo científico publicado en 2016

Pleomorphic lobular carcinoma of the breast: molecular pathology and clinical impact.

artículo científico publicado en 2009

Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity

scholarly article by Jorge Reis-Filho et al published 2005 in Journal of Pathology

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype

artículo científico publicado en 2005

Profiling copy number alterations in cell-free tumour DNA using a single-reference

Profiling familial breast cancer

scientific article published on 01 April 2001

Progesterone receptor-positive eruptive syringoma associated with diabetes.

artículo científico publicado en 2003

Proliferation and differentiation in the human breast during pregnancy

scientific article published on 01 October 2000

Putting the brakes on cylindromatosis?

artículo científico publicado en 2004

Rad51 supports triple negative breast cancer metastasis

artículo científico publicado en 2014

Rare variants in the ATM gene and risk of breast cancer

artículo científico publicado en 2011

Reading protocol for dynamic contrast-enhanced MR images of the breast: sensitivity and specificity analysis.

artículo científico publicado en 2005

Recent advances in breast cancer research impacting clinical diagnostic practice

scientific article published on 16 January 2019

Relationship of the Breast Ductal Carcinoma In Situ Immune Microenvironment with Clinicopathological and Genetic Features

artículo científico publicado en 2017

Role of the executioner caspases during lens development.

artículo científico publicado en 2005

SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

artículo científico publicado en 2011

Salivary gland-like tumours of the breast: surgical and molecular pathology

artículo científico publicado en 2003

Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS).

artículo científico publicado en 2005

Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer

Signatures of mutational processes in human cancer

artículo científico publicado en 2013

Somatic mutations of the protein kinase gene family in human lung cancer

artículo científico publicado en 2005

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

artículo científico publicado en 2017

Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast

artículo científico publicado en 2006

Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence variants identifies clinically significant splicing aberrations up to 12 nucleotides from the intron/exon boundary

artículo científico publicado en 2011

Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group

artículo científico publicado en 2016

Subtypes of familial breast tumours revealed by expression and copy number profiling

artículo científico publicado en 2009

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia.

artículo científico publicado en 2007

The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS)

artículo científico publicado en 2002

The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours

scientific article published on 01 April 2002

The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin.

artículo científico publicado en 2016

The cancer genetics and pathology of male breast cancer

artículo científico publicado en 2016

The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers

artículo científico publicado en 2010

The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas

artículo científico publicado en 1996

The diagnosis and management of pre-invasive breast disease Genetic alterations in pre-invasive lesions

artículo científico publicado el 9 de octubre de 2003

The diagnosis and management of pre-invasive breast disease--current challenges, future hopes

artículo científico publicado en 2003

The diagnosis and management of pre-invasive breast disease: pathology of atypical lobular hyperplasia and lobular carcinoma in situ

artículo científico publicado en 2003

The expression patterns of integrin subunits on human breast tissues obtained during pregnancy

artículo científico publicado en 2002

The inframammary fold: contents, clinical significance and implications for immediate breast reconstruction

artículo científico publicado en 2004

The landscape of cancer genes and mutational processes in breast cancer

artículo científico publicado en 2012

The mammary myoepithelial cell--Cinderella or ugly sister?

artículo científico publicado en 2000

The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?

artículo científico publicado en 2006

The molecular genetics of breast cancer: the contribution of comparative genomic hybridization

artículo científico publicado en 2005

The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2

artículo científico publicado en 2000

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

artículo científico publicado en 2002

The teaching of pathology at St. George's Hospital Medical School, London

artículo científico publicado en 1990

The topography of mutational processes in breast cancer genomes

artículo científico publicado en 2016

Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer

scientific article published on 18 May 2020

Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor

artículo científico publicado en 2013

Tumor heterogeneity in a follicular carcinoma of thyroid: a study by comparative genomic hybridization

artículo científico publicado en 2011

Typical medullary breast carcinomas have a basal/myoepithelial phenotype.

artículo científico publicado en 2005

What's in a cancer syndrome? Genes, phenotype and pathology

artículo científico publicado en 2008

X-inactivation patch size in human female tissue confounds the assessment of tumor clonality

artículo científico publicado en 2003

cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells

artículo científico publicado en 2003

miR-139-5p is a regulator of metastatic pathways in breast cancer

artículo científico publicado en 2013