Lista de obras - Serena Carra - Dominio Público Uruguay

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

artículo científico publicado en 2016

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

artículo científico publicado en 2010

Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function.

artículo científico publicado en 2017

Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3).

artículo científico publicado en 2010

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

artículo científico publicado en 2011

Altered regulation of CREB by chronic antidepressant administration in the brain of transgenic mice with impaired glucocorticoid receptor function

artículo científico publicado en 2002

An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function

artículo científico publicado en 2017

An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8.

artículo científico publicado en 2017

Autophagy researchers

BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes

artículo científico publicado en 2020

BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity

artículo científico publicado en 2011

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.

artículo científico publicado en 2014

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

artículo científico

Chronic treatment with desipramine and fluoxetine modulate BDNF, CaMKKalpha and CaMKKbeta mRNA levels in the hippocampus of transgenic mice expressing antisense RNA against the glucocorticoid receptor

artículo científico publicado en 2004

Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.

artículo científico publicado en 2013

Cloning of mouse Ca2+/calmodulin-dependent protein kinase kinase beta (CaMKKbeta) and characterization of CaMKKbeta and CaMKKalpha distribution in the adult mouse brain

artículo científico publicado en 2003

Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin

artículo científico publicado en 2019

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

artículo científico

Differential autophagy power in the spinal cord and muscle of transgenic ALS mice.

artículo científico publicado en 2013

Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins.

artículo científico

Granulostasis: Protein Quality Control of RNP Granules ⬇️

artículo científico publicado en 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones ⬇️

artículo científico publicado el 15 de septiembre de 2010

Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

artículo científico publicado en 2021

HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.

artículo científico publicado en 2007

HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{alpha} phosphorylation

artículo científico publicado en 2008

HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells.

artículo científico publicado en 2005

Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases.

artículo científico publicado en 2010

Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

artículo científico publicado en 2014

Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.

artículo científico publicado en 2017

Modulation of glutamate receptors in response to the novel antipsychotic olanzapine in rats

artículo científico publicado en 2001

Nucleoli and Promyelocytic Leukemia Protein (PML) bodies are phase separated nuclear protein quality control compartments for misfolded proteins

scientific article published on 26 August 2019

Small heat shock proteins, protein degradation and protein aggregation diseases.

artículo científico publicado en 2011

Small heat shock proteins: multifaceted proteins with important implications for life

artículo científico publicado en 2019

Specific protein homeostatic functions of small heat-shock proteins increase lifespan.

artículo científico publicado en 2015

Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families.

artículo científico publicado en 2008

The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases.

artículo científico publicado en 2012

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

artículo científico publicado en 2017

The Role of the Protein Quality Control System in SBMA.

artículo científico publicado en 2015

The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.

artículo científico publicado en 2016

The family of mammalian small heat shock proteins (HSPBs): Implications in protein deposit diseases and motor neuropathies ⬇️

artículo científico publicado el 28 de marzo de 2012

The growing world of small heat shock proteins: from structure to functions

artículo científico publicado en 2017

The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones

artículo científico publicado en 2021

The regulation of the autophagic network and its implications for human disease

artículo científico publicado en 2013

The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.

artículo científico publicado en 2017

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells

artículo científico publicado en 2017

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

artículo científico publicado en 2010

The stress-inducible HspB8-Bag3 complex induces the eIF2alpha kinase pathway: implications for protein quality control and viral factory degradation?

artículo científico publicado en 2009

Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases

artículo científico publicado en 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Serena Carra

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function.

Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3).

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

Altered regulation of CREB by chronic antidepressant administration in the brain of transgenic mice with impaired glucocorticoid receptor function

An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function

An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8.

Autophagy researchers

BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes

BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

Chronic treatment with desipramine and fluoxetine modulate BDNF, CaMKKalpha and CaMKKbeta mRNA levels in the hippocampus of transgenic mice expressing antisense RNA against the glucocorticoid receptor

Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.

Cloning of mouse Ca2+/calmodulin-dependent protein kinase kinase beta (CaMKKbeta) and characterization of CaMKKbeta and CaMKKalpha distribution in the adult mouse brain

Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

Differential autophagy power in the spinal cord and muscle of transgenic ALS mice.

Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins.

Granulostasis: Protein Quality Control of RNP Granules ⬇️

Guidelines for the use and interpretation of assays for monitoring autophagy

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones ⬇️

Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.

HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{alpha} phosphorylation

HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells.

Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases.

Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.

Modulation of glutamate receptors in response to the novel antipsychotic olanzapine in rats

Nucleoli and Promyelocytic Leukemia Protein (PML) bodies are phase separated nuclear protein quality control compartments for misfolded proteins

Small heat shock proteins, protein degradation and protein aggregation diseases.

Small heat shock proteins: multifaceted proteins with important implications for life

Specific protein homeostatic functions of small heat-shock proteins increase lifespan.

Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families.

The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases.

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

The Role of the Protein Quality Control System in SBMA.

The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.

The family of mammalian small heat shock proteins (HSPBs): Implications in protein deposit diseases and motor neuropathies ⬇️

The growing world of small heat shock proteins: from structure to functions

The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones

The regulation of the autophagic network and its implications for human disease

The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

The stress-inducible HspB8-Bag3 complex induces the eIF2alpha kinase pathway: implications for protein quality control and viral factory degradation?

Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)