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Lista de obras de Juan Carlos Acosta

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

artículo científico publicado en 2013

A role for CXCR2 in senescence, but what about in cancer?

artículo científico publicado en 2009

Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells.

artículo científico

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

artículo científico publicado en 2017

Chemokine signaling via the CXCR2 receptor reinforces senescence

artículo científico publicado en 2008

Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability

artículo científico publicado en 2016

Control of senescence by CXCR2 and its ligands

artículo científico publicado en 2008

Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence

artículo científico publicado en 2021

Detecting the Senescence-Associated Secretory Phenotype (SASP) by High Content Microscopy Analysis

artículo científico publicado en 2017

High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle

artículo científico publicado en 2014

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

artículo científico publicado en 2009

Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?

artículo científico publicado en 2009

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

artículo científico publicado en 2019

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes

artículo científico publicado en 2005

MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide

artículo científico publicado en 2015

MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib.

artículo científico publicado en 2011

Measuring the Inflammasome in Oncogene-Induced Senescence

artículo científico publicado en 2019

Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest

artículo científico publicado en 2008

Nuclear pore density controls heterochromatin reorganization during senescence

PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359

scientific article published on 01 July 2018

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.

artículo científico publicado en 2018

Premature senescence in cells from patients with autosomal recessive hypercholesterolemia (ARH): evidence for a role for ARH in mitosis.

artículo científico publicado en 2011

SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.

artículo científico publicado en 2011

Senescence impairs successful reprogramming to pluripotent stem cells

artículo científico publicado en 2009

Senescence: a new weapon for cancer therapy

artículo científico

Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage

artículo científico publicado en 2022

Suppression of autophagy impedes glioblastoma development and induces senescence

artículo científico publicado en 2016

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

scientific article published on 05 June 2019

Unbiased Characterization of the Senescence-Associated Secretome Using SILAC-Based Quantitative Proteomics

scientific article published on 01 January 2013

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

artículo científico publicado en 2015

p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.

artículo científico publicado en 2005