Lista de obras - Ulla Mandel - Dominio Público Uruguay

A glycogene mutation map for discovery of diseases of glycosylation

artículo científico publicado en 2014

A novel monoclonal antibody to a defined peptide epitope in MUC16.

artículo científico publicado en 2015

A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody

scientific article published on 01 April 2019

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation

scientific article published on 01 August 2019

Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity

artículo científico publicado en 2012

Altered Expression of Epithelial Cell Surface Glycoconjugates and Intermediate Filaments at the Margins of Mucosal Wounds

artículo científico publicado en 1998

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

scientific article published on 18 June 2019

Asthma induction in mice leads to appearance of alpha2-3- and alpha2-6-linked sialic acid residues in respiratory goblet-like cells.

artículo científico publicado en 2008

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

artículo científico publicado en 2013

Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

scientific article published on 04 November 2020

Characterization of binding epitopes of CA125 monoclonal antibodies.

artículo científico publicado en 2014

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

artículo científico publicado en 2005

De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium. ⬇️

artículo científico publicado en 2017

Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients.

artículo científico publicado en 2011

Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.

artículo científico publicado en 2014

Display of the human mucinome with defined O-glycans by gene engineered cells

artículo científico publicado en 2021

Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo.

artículo científico publicado en 2004

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

scientific article published on June 2016

Engineering mammalian mucin-type O-glycosylation in plants.

artículo científico publicado en 2012

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

scientific article published on 30 April 2019

Expression of Mucin-1 in multiple myeloma and its precursors: correlation with glycosylation and subcellular localization

artículo científico publicado en 2014

Expression of the -Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa

scholarly article by Marie B Nygaard published in September 2018

GLYCAN-DIRECTED CAR-T CELLS.

artículo científico publicado en 2018

Generation and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16.

artículo científico publicado en 2017

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.

artículo científico publicado en 2012

Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process

artículo científico publicado en 2011

Loss of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 and reduced O-glycosylation in colon carcinoma cells selected for hepatic metastasis

artículo científico publicado en 2010

Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas

artículo científico publicado en 1997

Microarray Glycoprofiling of CA125 improves differential diagnosis of ovarian cancer.

artículo científico publicado en 2013

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

artículo científico publicado en 2011

Mucins and Truncated -Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours

scientific article published on 13 July 2018

Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer.

artículo científico publicado en 2016

Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell

scientific article published on 01 November 2019

O-linked glycosylation of the mucin domain of the herpes simplex virus type 1-specific glycoprotein gC-1 is temporally regulated in a seed-and-spread manner

artículo científico publicado en 2014

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

artículo científico publicado en 2013

Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

artículo científico publicado en 2012

Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery.

artículo científico publicado en 2015

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

artículo científico publicado en 2018

Reduced sulfation of muc5b is linked to xerostomia in patients with Sjögren syndrome.

artículo científico publicado en 2007

Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.

artículo científico publicado en 2010

ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.

artículo científico publicado en 2011

Seromic profiling of colorectal cancer patients with novel glycopeptide microarray

artículo científico publicado en 2011

Simple mucin-type carbohydrate antigens in pleomorphic adenomas.

artículo científico publicado en 1993

Simple mucin-type carbohydrates in normal and malignant human endometrium

artículo científico publicado en 1995

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

artículo científico publicado en 2013

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

artículo científico publicado en 2015

The Thomsen-Friedenreich (T) simple mucin-type carbohydrate antigen in salivary gland carcinomas

artículo científico publicado en 1995

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

artículo científico publicado en 2019

The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation

artículo científico publicado en 2007

Toward stable genetic engineering of human O-glycosylation in plants

article

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

artículo científico publicado en 2007

Lista de obras de Ulla Mandel

A glycogene mutation map for discovery of diseases of glycosylation

A novel monoclonal antibody to a defined peptide epitope in MUC16.

A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation

Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity

Altered Expression of Epithelial Cell Surface Glycoconjugates and Intermediate Filaments at the Margins of Mucosal Wounds

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

Asthma induction in mice leads to appearance of alpha2-3- and alpha2-6-linked sialic acid residues in respiratory goblet-like cells.

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

Characterization of binding epitopes of CA125 monoclonal antibodies.

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium. ⬇️

Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients.

Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.

Display of the human mucinome with defined O-glycans by gene engineered cells

Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo.

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

Engineering mammalian mucin-type O-glycosylation in plants.

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

Expression of Mucin-1 in multiple myeloma and its precursors: correlation with glycosylation and subcellular localization

Expression of the -Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa

GLYCAN-DIRECTED CAR-T CELLS.

Generation and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16.

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.

Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process

Loss of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 and reduced O-glycosylation in colon carcinoma cells selected for hepatic metastasis

Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas

Microarray Glycoprofiling of CA125 improves differential diagnosis of ovarian cancer.

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

Mucins and Truncated -Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours

Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer.

Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell

O-linked glycosylation of the mucin domain of the herpes simplex virus type 1-specific glycoprotein gC-1 is temporally regulated in a seed-and-spread manner

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery.

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

Reduced sulfation of muc5b is linked to xerostomia in patients with Sjögren syndrome.

Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.

ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.

Seromic profiling of colorectal cancer patients with novel glycopeptide microarray

Simple mucin-type carbohydrate antigens in pleomorphic adenomas.

Simple mucin-type carbohydrates in normal and malignant human endometrium

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

The Thomsen-Friedenreich (T) simple mucin-type carbohydrate antigen in salivary gland carcinomas

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation

Toward stable genetic engineering of human O-glycosylation in plants

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells