Lista de obras - Dmitry A. Gordenin - Dominio Público Uruguay

A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.

artículo científico publicado en 1999

A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast ⬇️

artículo científico publicado el 21 de julio de 2010

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

artículo científico publicado en 2015

APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis

artículo científico publicado en 2020

APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast.

artículo científico publicado en 2017

Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

artículo científico publicado en 2011

Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast.

artículo científico publicado en 1997

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

artículo científico publicado en 2013

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

artículo científico publicado en 2015

Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

scientific article published on 10 April 2020

Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.

artículo científico publicado en 2008

Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent

artículo científico publicado en 2012

Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability.

artículo científico publicado en 2001

Break-induced replication is a source of mutation clusters underlying kataegis

artículo científico publicado en 2014

Cadmium is a mutagen that acts by inhibiting mismatch repair.

artículo científico publicado en 2003

Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness

artículo científico publicado en 2014

Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.

artículo científico publicado en 2012

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms

artículo científico publicado en 2015

Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes

artículo científico publicado en 2010

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

artículo científico publicado en 2017

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

artículo científico publicado en 2020

Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing.

artículo científico publicado en 2006

Damage-induced localized hypermutability.

artículo científico publicado en 2011

Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t) ⬇️

artículo científico publicado el 1 de mayo de 1998

Factors Affecting Inverted Repeat Stimulation of Recombination and Deletion in Saccharomyces cerevisiae ⬇️

artículo científico publicado el 1 de abril de 1998

Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis

artículo científico publicado en 2008

Functional analysis of human FEN1 in Saccharomyces cerevisiae and its role in genome stability

artículo científico publicado en 1999

Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.

artículo científico publicado en 1999

Genome-wide model for the normal eukaryotic DNA replication fork.

artículo científico publicado en 2010

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency ⬇️

artículo científico publicado en 2017

Genomic and evolutionary classification of lung cancer in never smokers

artículo científico publicado en 2021

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

article

Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

artículo científico publicado en 2019

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

artículo científico publicado en 2014

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

artículo científico publicado en 2008

Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

artículo científico publicado en 1997

Hypermutation in human cancer genomes: footprints and mechanisms

artículo científico publicado en 2014

Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

scientific article published on 28 October 2019

Inverted DNA repeats: a source of eukaryotic genomic instability

artículo científico publicado en 1993

Michael Ter-Avanesyan (1949-2018) - Advent of the scientist

scientific article published on 06 January 2019

Mitotic intragenic recombination in the yeast Saccharomyces: marker-effects on conversion and reciprocity of recombination

artículo científico publicado en 1984

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

artículo científico publicado en 2018

Mutability of LYS2 gene in diploid Saccharomyces yeasts. II. Frequency of mutants induced by 6-N-hydroxylaminopurine and propiolactone

scientific article published on 01 October 1988

Mutation signatures specific to DNA alkylating agents in yeast and cancers

artículo científico publicado en 2020

Mutational heterogeneity in cancer and the search for new cancer-associated genes

artículo científico publicado en 2013

Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature

artículo científico publicado en 2019

Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.

artículo científico publicado en 1999

Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick

scientific article (publication date: 17 January 2003)

Precise excision of bacterial transposon Tn5 in yeast

scientific article published on 01 August 1988

Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

scientific article published on 13 May 2020

RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition

artículo científico publicado en 2012

Rapid genetic test for discrimination between haploid and polyploid transformants in Saccharomyces

artículo científico publicado en 1984

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

artículo científico publicado en 2019

Repeat expansion--all in a flap?

artículo científico publicado en 1997

Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes.

artículo científico publicado en 1995

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

scientific article published on 03 August 2020

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

scientific article published on 02 October 2020

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

artículo científico publicado en 2020

Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells

artículo científico publicado en 2018

Suppression of allelic recombination and aneuploidy by cohesin is independent of Chk1 in Saccharomyces cerevisiae.

artículo científico publicado en 2014

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

artículo científico publicado en 2001

The Repertoire of Mutational Signatures in Human Cancer

The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.

artículo científico publicado en 2002

The impact of environmental and endogenous damage on somatic mutation load in human skin fibroblasts

artículo científico publicado en 2016

The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains

artículo científico publicado en 2005

The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions.

artículo científico publicado en 1996

The repertoire of mutational signatures in human cancer

artículo científico publicado en 2020

The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.

artículo científico publicado en 2013

The somatic genomic landscape of chromophobe renal cell carcinoma

artículo científico publicado en 2014

The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1.

artículo científico publicado en 2008

Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes ⬇️

artículo científico publicado el 1 de mayo de 1992

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

artículo científico publicado en 2021

Who Is Leading the Replication Fork, Pol ε or Pol δ?

artículo científico publicado en 2016

Yeast ARMs (DNA at-risk motifs) can reveal sources of genome instability ⬇️

artículo científico publicado el 25 de mayo de 1998

Yeast mutants with increased bacterial transposon Tn5 excision.

artículo científico publicado en 1991

[Genetic analysis of spontaneous and 6-N-hydroxylaminopurine and propiolactone induced Adp+ mutants in Saccharomyces yeasts]

scientific article published on 01 July 1990

[Genetic express-test for distinguishing between haploids and autodiploids in the yeast Saccharomyces]

artículo científico publicado en 1983

[Mechanism of mutant induction in the ade2 gene of diploid Saccharomyces cerevisiae yeasts by ultraviolet rays]

artículo científico publicado en 1981

[Mutability of the LYS2 gene in diploid saccharomycete yeasts. I. The occurrence of spontaneous mutants and mutants induced by x-ray and ultraviolet radiation]

artículo científico publicado en 1985

[New marker effect of intragenic recombination in saccharomycete yeasts]

scientific article published on 01 January 1984

[Phenotypic manifestations of yeast transposon insertion in the LYS2 gene and deletions resulting from imprecise excision of the transposon]

artículo científico publicado en 1987

Lista de obras de Dmitry A. Gordenin

A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.

A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast ⬇️

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis

APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast.

Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast.

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.

Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent

Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability.

Break-induced replication is a source of mutation clusters underlying kataegis

Cadmium is a mutagen that acts by inhibiting mismatch repair.

Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness

Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms

Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing.

Damage-induced localized hypermutability.

Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t) ⬇️

Factors Affecting Inverted Repeat Stimulation of Recombination and Deletion in Saccharomyces cerevisiae ⬇️

Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis

Functional analysis of human FEN1 in Saccharomyces cerevisiae and its role in genome stability

Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.

Genome-wide model for the normal eukaryotic DNA replication fork.

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency ⬇️

Genomic and evolutionary classification of lung cancer in never smokers

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

Hypermutation in human cancer genomes: footprints and mechanisms

Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

Inverted DNA repeats: a source of eukaryotic genomic instability

Michael Ter-Avanesyan (1949-2018) - Advent of the scientist

Mitotic intragenic recombination in the yeast Saccharomyces: marker-effects on conversion and reciprocity of recombination

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

Mutability of LYS2 gene in diploid Saccharomyces yeasts. II. Frequency of mutants induced by 6-N-hydroxylaminopurine and propiolactone

Mutation signatures specific to DNA alkylating agents in yeast and cancers

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature

Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.

Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick

Precise excision of bacterial transposon Tn5 in yeast

Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition

Rapid genetic test for discrimination between haploid and polyploid transformants in Saccharomyces

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Repeat expansion--all in a flap?

Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes.

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells

Suppression of allelic recombination and aneuploidy by cohesin is independent of Chk1 in Saccharomyces cerevisiae.

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

The Repertoire of Mutational Signatures in Human Cancer

The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.

The impact of environmental and endogenous damage on somatic mutation load in human skin fibroblasts

The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains

The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions.

The repertoire of mutational signatures in human cancer

The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.

The somatic genomic landscape of chromophobe renal cell carcinoma

The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1.

Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes ⬇️

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

Who Is Leading the Replication Fork, Pol ε or Pol δ?

Yeast ARMs (DNA at-risk motifs) can reveal sources of genome instability ⬇️

Yeast mutants with increased bacterial transposon Tn5 excision.

[Genetic analysis of spontaneous and 6-N-hydroxylaminopurine and propiolactone induced Adp+ mutants in Saccharomyces yeasts]

[Genetic express-test for distinguishing between haploids and autodiploids in the yeast Saccharomyces]

[Mechanism of mutant induction in the ade2 gene of diploid Saccharomyces cerevisiae yeasts by ultraviolet rays]

[Mutability of the LYS2 gene in diploid saccharomycete yeasts. I. The occurrence of spontaneous mutants and mutants induced by x-ray and ultraviolet radiation]