Lista de obras - Yardena Samuels - Dominio Público Uruguay

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma

scientific article published on 10 October 2019

A growing family: adding mutated Erbb4 as a novel cancer target

artículo científico publicado en 2010

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma

artículo científico publicado en 2011

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

artículo científico publicado en 2009

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

artículo científico publicado en 2009

Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes

scientific article published on 01 August 1998

Colorectal cancer: mutations in a signalling pathway

artículo científico publicado en 2005

Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma

article

Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

artículo científico publicado en 2017

Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma ⬇️

artículo científico publicado el 24 de septiembre de 2012

Cross-Talk between Receptor Tyrosine Kinases AXL and ERBB3 Regulates Invadopodia Formation in Melanoma Cells

artículo científico publicado en 2019

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.

artículo científico publicado en 2015

Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.

artículo científico publicado en 2014

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

artículo científico publicado en 2011

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

artículo científico publicado en 2011

Frequent mutations in the MITF pathway in melanoma

artículo científico publicado en 2009

Genetic and Functional Analysis of GRIN2A in Tumor Samples.

artículo científico publicado en 2017

Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation

artículo científico publicado en 2010

High frequency of mutations of the PIK3CA gene in human cancers

artículo científico publicado en 2004

IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain

artículo científico publicado en 2010

MEK inhibition reverses aberrant signaling in melanoma cells through reorganization of NRas and BRAF in self nano-clusters

artículo científico publicado en 2020

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

artículo científico publicado en 2013

Molecular Pathways: Dysregulated Glutamatergic Signaling Pathways in Cancer ⬇️

artículo científico publicado el 30 de mayo de 2012

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

artículo científico publicado en 2005

Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.

artículo científico publicado en 2013

Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma

artículo científico publicado en 2014

Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma

artículo científico publicado en 2010

Mutational inactivation of STAG2 causes aneuploidy in human cancer

artículo científico publicado en 2011

Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

artículo científico publicado en 2016

Oncogenic mutations of PIK3CA in human cancers

scientific article published on 12 October 2004

Parkin Somatic Mutations Link Melanoma and Parkinson's Disease

artículo científico publicado en 2016

Parkinson disease (PARK) genes are somatically mutated in cutaneous melanoma

artículo científico publicado en 2016

RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells

artículo científico publicado en 2018

Recurrent inactivating RASA2 mutations in melanoma

artículo científico publicado en 2015

Refinement of the Endogenous Epitope Tagging (EET) Technology Allows the Identification of a Novel NRAS Binding Partner in Melanoma.

artículo científico publicado en 2018

Sequence mutations and amplification of PIK3CA and AKT2 genes in purified ovarian serous neoplasms

artículo científico publicado en 2006

Serial Assessment of Human Tumor Burdens in Mice by the Analysis of Circulating DNA

article

Shimmer: detection of genetic alterations in tumors using next-generation sequence data

artículo científico publicado en 2013

Somatic mutation of GRIN2A in malignant melanoma results in loss of tumor suppressor activity via aberrant NMDAR complex formation

artículo científico publicado en 2014

Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin

artículo científico publicado en 2014

Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications.

artículo científico publicado en 2016

TYRO3-mediated regulation of MITF: a novel target in melanoma?

artículo científico publicado en 2009

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

artículo científico publicado en 2018

The functional relevance of somatic synonymous mutations in melanoma and other cancers

artículo científico publicado en 2015

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

artículo científico publicado en 2007

Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens.

artículo científico publicado en 2016

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

artículo científico publicado en 2013

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

artículo científico publicado en 2003

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

artículo científico publicado en 2006

Lista de obras de Yardena Samuels

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma

A growing family: adding mutated Erbb4 as a novel cancer target

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes

Colorectal cancer: mutations in a signalling pathway

Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma

Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma ⬇️

Cross-Talk between Receptor Tyrosine Kinases AXL and ERBB3 Regulates Invadopodia Formation in Melanoma Cells

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.

Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

Frequent mutations in the MITF pathway in melanoma

Genetic and Functional Analysis of GRIN2A in Tumor Samples.

Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation

High frequency of mutations of the PIK3CA gene in human cancers

IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain

MEK inhibition reverses aberrant signaling in melanoma cells through reorganization of NRas and BRAF in self nano-clusters

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

Molecular Pathways: Dysregulated Glutamatergic Signaling Pathways in Cancer ⬇️

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.

Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma

Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma

Mutational inactivation of STAG2 causes aneuploidy in human cancer

Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

Oncogenic mutations of PIK3CA in human cancers

Parkin Somatic Mutations Link Melanoma and Parkinson's Disease

Parkinson disease (PARK) genes are somatically mutated in cutaneous melanoma

RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells

Recurrent inactivating RASA2 mutations in melanoma

Refinement of the Endogenous Epitope Tagging (EET) Technology Allows the Identification of a Novel NRAS Binding Partner in Melanoma.

Sequence mutations and amplification of PIK3CA and AKT2 genes in purified ovarian serous neoplasms

Serial Assessment of Human Tumor Burdens in Mice by the Analysis of Circulating DNA

Shimmer: detection of genetic alterations in tumors using next-generation sequence data

Somatic mutation of GRIN2A in malignant melanoma results in loss of tumor suppressor activity via aberrant NMDAR complex formation

Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin

Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications.

TYRO3-mediated regulation of MITF: a novel target in melanoma?

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

The functional relevance of somatic synonymous mutations in melanoma and other cancers

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens.

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.