Lista de obras - Gary G. Chiang - Dominio Público Uruguay

Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect

artículo científico publicado en 2011

Control of mTORC1 signaling by the Opitz syndrome protein MID1.

artículo científico publicado en 2011

Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase

artículo científico publicado en 2020

Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway

artículo científico publicado en 2010

Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors

artículo científico publicado en 2017

Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

artículo científico publicado en 2014

Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.

artículo científico publicado en 2015

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

artículo científico publicado en 2017

Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways

artículo científico publicado en 2011

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

artículo científico publicado en 2005

Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold

artículo científico publicado en 2004

Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis

artículo científico publicado en 2010

Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

artículo científico publicado en 2005

REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase

artículo científico publicado en 2009

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

artículo científico publicado en 2002

SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).

artículo científico publicado en 2017

SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding

artículo científico publicado en 2017

Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase

artículo científico publicado en 2001

Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.

artículo científico publicado en 2018

Targeting oncogene mRNA translation in B cell malignancies with eFT226, a potent and selective inhibitor of eIF4A1

scientific article published on 09 October 2020

Targeting the mTOR signaling network in cancer.

artículo científico publicado en 2007

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

artículo científico publicado en 2017

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia

artículo científico publicado en 2015

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

artículo científico publicado en 2017

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

artículo científico publicado en 2008

Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice ⬇️

artículo científico publicado el 12 de octubre de 2010

Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product.

artículo científico publicado en 1997

Lista de obras de Gary G. Chiang

Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect

Control of mTORC1 signaling by the Opitz syndrome protein MID1.

Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase

Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway

Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors

Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold

Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis

Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).

SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding

Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase

Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.

Targeting oncogene mRNA translation in B cell malignancies with eFT226, a potent and selective inhibitor of eIF4A1

Targeting the mTOR signaling network in cancer.

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice ⬇️

Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product.