Lista de obras - Alon Chen - Dominio Público Uruguay

A Methyl-Balanced Diet Prevents CRF-Induced Prenatal Stress-Triggered Predisposition to Binge Eating-like Phenotype.

artículo científico publicado en 2017

A paradigm shift in translational psychiatry through rodent neuroethology

artículo científico publicado en 2023

A second isoform of gonadotropin-releasing hormone is present in the brain of human and rodents.

artículo científico publicado en 1998

A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity

artículo científico publicado en 2005

A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery ⬇️

artículo científico publicado el 11 de octubre de 2010

ACTH-Dependent Regulation of MicroRNA As Endogenous Modulators of Glucocorticoid Receptor Expression in the Adrenal Gland

Adipose tissue foam cells are present in human obesity

artículo científico publicado en 2013

Amelioration of brain pathology and behavioral dysfunction in mice with lupus following treatment with a tolerogenic peptide.

artículo científico publicado en 2009

Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress

artículo científico publicado en 2016

An anxiolytic role for CRF receptor type 1 in the globus pallidus.

artículo científico publicado en 2011

An environmental enrichment model for mice.

artículo científico publicado en 2010

An exploratory study of adolescent response to fluoxetine using psychological and biological predictors

artículo científico publicado en 2018

CRF receptor type 2 neurons in the posterior bed nucleus of the stria terminalis critically contribute to stress recovery.

artículo científico publicado en 2016

CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting.

artículo científico publicado en 2016

Cerebellar Learning Properties Are Modulated by the CRF Receptor

artículo científico publicado en 2018

Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety

artículo científico publicado en 2018

Chronic activation of corticotropin-releasing factor type 2 receptors reveals a key role for 5-HT1A receptor responsiveness in mediating behavioral and serotonergic responses to stressful challenge.

artículo científico publicado en 2012

Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat

artículo científico publicado en 2011

Control of chronic excessive alcohol drinking by genetic manipulation of the Edinger-Westphal nucleus urocortin-1 neuropeptide system.

artículo científico publicado en 2017

Correction: High-order social interactions in groups of mice.

artículo científico publicado en 2014

Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood.

artículo científico publicado en 2017

Determining the role of microRNAs in psychiatric disorders

artículo científico

Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

artículo científico publicado en 2014

Dnmt3a in the Medial Prefrontal Cortex Regulates Anxiety-Like Behavior in Adult Mice

artículo científico publicado en 2016

Enhancement of consolidated long-term memory by overexpression of protein kinase Mzeta in the neocortex.

artículo científico publicado en 2011

Expression and regulation of corticotropin-releasing factor receptor type 2β in developing and mature mouse skeletal muscle.

artículo científico publicado en 2010

Forebrain glutamatergic, but not GABAergic, neurons mediate anxiogenic effects of the glucocorticoid receptor.

artículo científico publicado en 2016

GABA receptors in a state of fear

artículo científico publicado en 2015

Genetic predisposition for high stress reactivity amplifies effects of early-life adversity.

artículo científico publicado en 2016

Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice.

artículo científico publicado en 2016

Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD

artículo científico publicado en 2019

Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality.

artículo científico publicado en 2017

High-order social interactions in groups of mice.

artículo científico publicado en 2013

Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress

artículo científico publicado en 2012

Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress.

artículo científico publicado en 2017

Hypothalamic corticotropin-releasing factor is centrally involved in learning under moderate stress.

artículo científico publicado en 2013

Hypothalamic miR-219 regulates individual metabolic differences in response to diet-induced weight cycling.

artículo científico publicado en 2018

Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity

artículo científico publicado en 2013

Identity domains capture individual differences from across the behavioral repertoire

scientific article published on 04 November 2019

Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas.

artículo científico publicado en 2014

Inferior olive CRF plays a role in motor performance under challenging conditions.

artículo científico publicado en 2018

Knockdown of corticotropin-releasing factor 1 receptors in the ventral tegmental area enhances conditioned fear

artículo científico publicado en 2016

Late-Onset Cognitive Impairments after Early-Life Stress Are Shaped by Inherited Differences in Stress Reactivity.

artículo científico publicado en 2017

Local Optogenetic Induction of Fast (20-40 Hz) Pyramidal-Interneuron Network Oscillations in the In Vitro and In Vivo CA1 Hippocampus: Modulation by CRF and Enforcement of Perirhinal Theta Activity

artículo científico publicado en 2016

Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons

scientific article published on 02 October 2020

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

artículo científico publicado en 2014

MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34.

artículo científico publicado en 2011

MicroRNA-19b associates with Ago2 in the amygdala following chronic stress and regulates the adrenergic receptor beta 1.

artículo científico publicado en 2014

Minireview: CRF and Wylie Vale: A Story of 41 Amino Acids and a Texan with Grit ⬇️

artículo científico publicado el 4 de abril de 2012

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids

scientific journal article

Neuro-Epigenetic Indications of Acute Stress Response in Humans: The Case of MicroRNA-29c

artículo científico publicado en 2016

Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disorders

artículo científico publicado en 2016

Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis

artículo científico publicado en 2010

Pharmacogenetics of citalopram-related side effects in children with depression and/or anxiety disorders

artículo científico publicado en 2016

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties.

artículo científico publicado en 2015

Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors

artículo científico publicado en 2013

Placental miR-340 mediates vulnerability to activity based anorexia in mice.

artículo científico publicado en 2018

Postnatal ablation of POMC neurons induces an obese phenotype characterized by decreased food intake and enhanced anxiety-like behavior.

artículo científico publicado en 2013

Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction

artículo científico publicado en 2016

Prenatal Exposure to Maternal Obesity Alters Anxiety and Stress Coping Behaviors in Aged Mice.

artículo científico publicado en 2015

Prolonged and site-specific over-expression of corticotropin-releasing factor reveals differential roles for extended amygdala nuclei in emotional regulation.

artículo científico publicado en 2010

Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner.

artículo científico publicado en 2011

Receptor-mediated targeting of a photosensitizer by its conjugation to gonadotropin-releasing hormone analogues.

artículo científico publicado en 2003

Region-specific roles of the corticotropin-releasing factor-urocortin system in stress.

artículo científico publicado en 2016

Resilience to chronic stress is mediated by hippocampal brain-derived neurotrophic factor.

artículo científico publicado en 2011

Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice.

artículo científico publicado en 2010

SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system

artículo científico publicado en 2015

Selective expression of neuropeptides in the rat mammary gland: somatostatin gene is expressed during lactation

scientific article published on 01 December 1999

Sex differences in corticotropin-releasing factor receptor-1 action within the dorsal raphe nucleus in stress responsivity

scientific article published on 23 October 2013

Sex differences: Transcriptional signatures of stress exposure in male and female brains

scientific article published on 06 February 2020

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation

artículo científico

Social context and dominance status contribute to sleep patterns and quality in groups of freely-moving mice

artículo científico publicado en 2019

Social dominance mediates behavioral adaptation to chronic stress in a sex-specific manner

artículo científico publicado en 2020

Specificity and regulation of extracellularly regulated kinase1/2 phosphorylation through corticotropin-releasing factor (CRF) receptors 1 and 2beta by the CRF/urocortin family of peptides

artículo científico publicado en 2003

Stable isotope metabolic labeling suggests differential turnover of the DPYSL protein family.

artículo científico publicado en 2016

Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.

artículo científico publicado en 2017

Susceptibility to PTSD-like behavior is mediated by corticotropin-releasing factor receptor type 2 levels in the bed nucleus of the stria terminalis.

artículo científico publicado en 2012

The CRF family of neuropeptides and their receptors - mediators of the central stress response

artículo científico publicado en 2017

The Corticotropin-Releasing Factor Family: Physiology of the Stress Response

artículo científico publicado en 2018

The Relationship Between Plasma Cytokine Levels and Response to Selective Serotonin Reuptake Inhibitor Treatment in Children and Adolescents with Depression and/or Anxiety Disorders.

artículo científico publicado en 2016

The anxiolytic effect of environmental enrichment is mediated via amygdalar CRF receptor type 1.

artículo científico publicado en 2010

The effect of magnesium sulfate on the placental corticotropin-releasing factor (CRF) and CRF binding protein mRNA expression in perfused human placental cotyledon.

artículo científico publicado en 2015

The emerging role of mRNA methylation in normal and pathological behavior.

artículo científico publicado en 2017

The gonadotropin-releasing hormone family of neuropeptides in the brain of human, bovine and rat: identification of a third isoform

artículo científico publicado en 1999

Topographical distribution of corticotropin-releasing factor type 2 receptor-like immunoreactivity in the rat dorsal raphe nucleus: co-localization with tryptophan hydroxylase

scientific journal article

Transcriptional Regulation of the Human GnRH II Gene Is Mediated by a Putative cAMP Response Element

article

Trisomy of the G protein-coupled K+channel gene,Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice ⬇️

artículo científico publicado el 30 de enero de 2012

Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics.

artículo científico publicado en 2016

Urocortin 2-deficient mice exhibit gender-specific alterations in circadian hypothalamus-pituitary-adrenal axis and depressive-like behavior.

artículo científico publicado en 2006

Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet.

artículo científico publicado en 2011

Urocortin II gene is highly expressed in mouse skin and skeletal muscle tissues: localization, basal expression in corticotropin-releasing factor receptor (CRFR) 1- and CRFR2-null mice, and regulation by glucocorticoids.

artículo científico publicado en 2004

Urocortin-1 and -2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits.

artículo científico publicado en 2009

Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart.

artículo científico publicado en 2003

Urocortin-dependent effects on adrenal morphology, growth, and expression of steroidogenic enzymes in vivo

scholarly article by Anna Riester published in February 2012

Urocortins: CRF's siblings and their potential role in anxiety, depression and alcohol drinking behavior.

artículo científico publicado en 2012

Urocortins: emerging metabolic and energy homeostasis perspectives

artículo científico publicado en 2008

Using (15)N-Metabolic Labeling for Quantitative Proteomic Analyses

artículo científico publicado en 2017

miRNA malfunction causes spinal motor neuron disease

artículo científico publicado en 2010

Lista de obras de Alon Chen

A Methyl-Balanced Diet Prevents CRF-Induced Prenatal Stress-Triggered Predisposition to Binge Eating-like Phenotype.

A paradigm shift in translational psychiatry through rodent neuroethology

A second isoform of gonadotropin-releasing hormone is present in the brain of human and rodents.

A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity

A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery ⬇️

ACTH-Dependent Regulation of MicroRNA As Endogenous Modulators of Glucocorticoid Receptor Expression in the Adrenal Gland

Adipose tissue foam cells are present in human obesity

Amelioration of brain pathology and behavioral dysfunction in mice with lupus following treatment with a tolerogenic peptide.

Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress

An anxiolytic role for CRF receptor type 1 in the globus pallidus.

An environmental enrichment model for mice.

An exploratory study of adolescent response to fluoxetine using psychological and biological predictors

CRF receptor type 2 neurons in the posterior bed nucleus of the stria terminalis critically contribute to stress recovery.

CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting.

Cerebellar Learning Properties Are Modulated by the CRF Receptor

Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety

Chronic activation of corticotropin-releasing factor type 2 receptors reveals a key role for 5-HT1A receptor responsiveness in mediating behavioral and serotonergic responses to stressful challenge.

Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat

Control of chronic excessive alcohol drinking by genetic manipulation of the Edinger-Westphal nucleus urocortin-1 neuropeptide system.

Correction: High-order social interactions in groups of mice.

Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood.

Determining the role of microRNAs in psychiatric disorders

Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

Dnmt3a in the Medial Prefrontal Cortex Regulates Anxiety-Like Behavior in Adult Mice

Enhancement of consolidated long-term memory by overexpression of protein kinase Mzeta in the neocortex.

Expression and regulation of corticotropin-releasing factor receptor type 2β in developing and mature mouse skeletal muscle.

Forebrain glutamatergic, but not GABAergic, neurons mediate anxiogenic effects of the glucocorticoid receptor.

GABA receptors in a state of fear

Genetic predisposition for high stress reactivity amplifies effects of early-life adversity.

Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice.

Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD

Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality.

High-order social interactions in groups of mice.

Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress

Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress.

Hypothalamic corticotropin-releasing factor is centrally involved in learning under moderate stress.

Hypothalamic miR-219 regulates individual metabolic differences in response to diet-induced weight cycling.

Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity

Identity domains capture individual differences from across the behavioral repertoire

Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas.

Inferior olive CRF plays a role in motor performance under challenging conditions.

Knockdown of corticotropin-releasing factor 1 receptors in the ventral tegmental area enhances conditioned fear

Late-Onset Cognitive Impairments after Early-Life Stress Are Shaped by Inherited Differences in Stress Reactivity.

Local Optogenetic Induction of Fast (20-40 Hz) Pyramidal-Interneuron Network Oscillations in the In Vitro and In Vivo CA1 Hippocampus: Modulation by CRF and Enforcement of Perirhinal Theta Activity

Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34.

MicroRNA-19b associates with Ago2 in the amygdala following chronic stress and regulates the adrenergic receptor beta 1.

Minireview: CRF and Wylie Vale: A Story of 41 Amino Acids and a Texan with Grit ⬇️

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids

Neuro-Epigenetic Indications of Acute Stress Response in Humans: The Case of MicroRNA-29c

Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disorders

Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis

Pharmacogenetics of citalopram-related side effects in children with depression and/or anxiety disorders

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties.

Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors

Placental miR-340 mediates vulnerability to activity based anorexia in mice.

Postnatal ablation of POMC neurons induces an obese phenotype characterized by decreased food intake and enhanced anxiety-like behavior.

Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction

Prenatal Exposure to Maternal Obesity Alters Anxiety and Stress Coping Behaviors in Aged Mice.

Prolonged and site-specific over-expression of corticotropin-releasing factor reveals differential roles for extended amygdala nuclei in emotional regulation.

Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner.

Receptor-mediated targeting of a photosensitizer by its conjugation to gonadotropin-releasing hormone analogues.

Region-specific roles of the corticotropin-releasing factor-urocortin system in stress.

Resilience to chronic stress is mediated by hippocampal brain-derived neurotrophic factor.

Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice.

SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system

Selective expression of neuropeptides in the rat mammary gland: somatostatin gene is expressed during lactation

Sex differences in corticotropin-releasing factor receptor-1 action within the dorsal raphe nucleus in stress responsivity

Sex differences: Transcriptional signatures of stress exposure in male and female brains

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation

Social context and dominance status contribute to sleep patterns and quality in groups of freely-moving mice

Social dominance mediates behavioral adaptation to chronic stress in a sex-specific manner

Specificity and regulation of extracellularly regulated kinase1/2 phosphorylation through corticotropin-releasing factor (CRF) receptors 1 and 2beta by the CRF/urocortin family of peptides

Stable isotope metabolic labeling suggests differential turnover of the DPYSL protein family.

Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.

Susceptibility to PTSD-like behavior is mediated by corticotropin-releasing factor receptor type 2 levels in the bed nucleus of the stria terminalis.

The CRF family of neuropeptides and their receptors - mediators of the central stress response

The Corticotropin-Releasing Factor Family: Physiology of the Stress Response