Lista de obras - Abraham Acevedo-Arozena - Dominio Público Uruguay

A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

artículo científico publicado en 2011

A genetic modifier suggests that endurance exercise exacerbates Huntington's disease

artículo científico publicado en 2018

A new locus for resistance to gamma-radiation-induced thymic lymphoma identified using inter-specific consomic and inter-specific recombinant congenic strains of mice.

artículo científico publicado en 2002

A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects

scientific article published on 21 January 2014

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

artículo científico publicado en 2014

Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System

artículo científico publicado en 2016

Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse

artículo científico publicado en 2011

Cancer modifier alleles inhibiting lung tumorigenesis are common in inbred mouse strains.

artículo científico publicado en 2002

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration

artículo científico publicado en 2015

Dynein mutations impair autophagic clearance of aggregate-prone proteins

artículo científico publicado en 2005

Dyneins, autophagy, aggregation and neurodegeneration

artículo científico publicado en 2005

EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome

artículo científico publicado en 2019

ENU mutagenesis, a way forward to understand gene function

artículo científico publicado en 2008

Effects of dopaminergic cell degeneration on electrophysiological characteristics and GAD65/GAD67 expression in the substantia nigra: different action on GABA cell subpopulations.

artículo científico publicado en 2003

Estrogen modulates norepinephrine-induced accumulation of adenosine cyclic monophosphate in a subpopulation of immortalized luteinizing hormone-releasing hormone secreting neurons from the mouse hypothalamus.

artículo científico publicado en 2001

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice.

artículo científico publicado en 2004

Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.

artículo científico publicado en 2017

IGF-1 receptor antagonism inhibits autophagy

artículo científico publicado en 2013

Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by tacrolimus

artículo científico publicado en 2019

Loss of disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

artículo científico publicado en 2019

Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy

scientific journal article

Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.

artículo científico publicado en 2018

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

artículo científico publicado en 2016

Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis

artículo científico publicado en 2014

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease

artículo científico publicado en 2013

Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease

artículo científico publicado en 2017

Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice

artículo científico publicado en 2014

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

artículo científico publicado en 2010

SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments

artículo científico publicado en 2011

Skeletal Muscle Modulates Huntington's Disease Pathogenesis in Mice: Role of Physical Exercise

artículo científico publicado en 2018

TDP-43 mutations increase HNRNP A1-7B through gain of splicing function

artículo científico publicado en 2018

Towards humane end points: behavioural changes precede clinical signs of disease in a Huntington's disease model.

artículo científico publicado en 2008

Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis

artículo científico publicado en 2019

Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy

artículo científico publicado en 2013

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

artículo científico publicado en 2010

α-Synuclein levels affect autophagosome numbers in vivo and modulate Huntington disease pathology

artículo científico publicado en 2012

α-Synuclein levels modulate Huntington's disease in mice

artículo científico publicado en 2011

α-Synuclein levels modulate Huntington's disease in mice.

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Abraham Acevedo-Arozena

A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

A genetic modifier suggests that endurance exercise exacerbates Huntington's disease

A new locus for resistance to gamma-radiation-induced thymic lymphoma identified using inter-specific consomic and inter-specific recombinant congenic strains of mice.

A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System

Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse

Cancer modifier alleles inhibiting lung tumorigenesis are common in inbred mouse strains.

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration

Dynein mutations impair autophagic clearance of aggregate-prone proteins

Dyneins, autophagy, aggregation and neurodegeneration

EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome

ENU mutagenesis, a way forward to understand gene function

Effects of dopaminergic cell degeneration on electrophysiological characteristics and GAD65/GAD67 expression in the substantia nigra: different action on GABA cell subpopulations.

Estrogen modulates norepinephrine-induced accumulation of adenosine cyclic monophosphate in a subpopulation of immortalized luteinizing hormone-releasing hormone secreting neurons from the mouse hypothalamus.

Guidelines for the use and interpretation of assays for monitoring autophagy

Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice.

Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.

IGF-1 receptor antagonism inhibits autophagy

Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by tacrolimus

Loss of disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy

Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease

Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease

Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments

Skeletal Muscle Modulates Huntington's Disease Pathogenesis in Mice: Role of Physical Exercise

TDP-43 mutations increase HNRNP A1-7B through gain of splicing function

Towards humane end points: behavioural changes precede clinical signs of disease in a Huntington's disease model.

Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis

Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

α-Synuclein levels affect autophagosome numbers in vivo and modulate Huntington disease pathology

α-Synuclein levels modulate Huntington's disease in mice

α-Synuclein levels modulate Huntington's disease in mice.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)