Lista de obras - Erkki Koivunen - Dominio Público Uruguay

A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide

artículo científico publicado en 2010

A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth

artículo científico publicado en 2009

A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins

artículo científico publicado en 1995

A polymeric form of fibronectin has antimetastatic effects against multiple tumor types.

artículo científico publicado en 1996

A tripeptide mimetic of von Willebrand factor residues 981-983 enhances platelet adhesion to fibrinogen by signaling through integrin alpha(IIb)beta3.

artículo científico publicado en 2005

Activation of Type IV Procollagenases by Human Tumor-associated Trypsin-2 ⬇️

artículo científico publicado el 22 de agosto de 1997

Alpha v integrins as receptors for tumor targeting by circulating ligands.

artículo científico publicado en 1997

AlphaMbeta2 integrin modulator exerts antitumor activity in vivo

artículo científico publicado en 2007

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis

artículo científico publicado en 2000

An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.

artículo científico publicado en 2009

Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro

artículo científico publicado en 2001

Biology and function of tumor-associated trypsin inhibitor, TATI.

artículo científico publicado en 1991

Cell-surface association between matrix metalloproteinases and integrins: role of the complexes in leukocyte migration and cancer progression

artículo científico publicado en 2006

Cell-surface interactions of echovirus 22.

artículo científico publicado en 1997

Characteristics of soluble tumour-derived proteins that inhibit natural killer activity

scientific article published on 01 July 1988

Characterization of a tumor-associated serine protease

artículo científico publicado en 1988

Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells

artículo científico publicado en 2012

Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells

artículo científico publicado en 2008

Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment

artículo científico publicado en 2012

Cyst fluid of ovarian cancer patients contains high concentrations of trypsinogen-2

artículo científico publicado en 1990

Design, development, and validation of a high-throughput drug-screening assay for targeting of human leukemia

artículo científico publicado en 2013

Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis

scientific article published on 01 May 1989

Development of novel peptide ligands modulating the enzyme activity of prostate-specific antigen

artículo científico publicado en 2000

Down-regulation of trypsinogen-2 expression by chemically modified tetracyclines: association with reduced cancer cell migration

scientific article published on 01 May 2000

Gelatinase-mediated migration and invasion of cancer cells

artículo científico publicado en 2005

Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate

artículo científico publicado en 2009

Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen

scientific article published on 01 February 1991

Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase

artículo científico publicado en 1989

Human tongue carcinoma growth is inhibited by selective antigelatinolytic peptides

scientific article published on 01 May 2006

Identification of a negatively charged peptide motif within the catalytic domain of progelatinases that mediates binding to leukocyte beta 2 integrins

artículo científico publicado en 2003

Identification of novel peptide inhibitors for human trypsins.

artículo científico publicado en 2010

Identification of novel prostate-specific antigen-binding peptides modulating its enzyme activity.

artículo científico publicado en 2000

Identification of receptor ligands with phage display peptide libraries

artículo científico publicado en 1999

In vivo localization of gelatinases (MMP-2 and -9) by in situ zymography with a selective gelatinase inhibitor

artículo científico publicado en 2001

In vivo targeting of activated leukocytes by a β2-integrin binding peptide

artículo científico publicado en 2014

Inhibition of beta(2) integrin-mediated leukocyte cell adhesion by leucine-leucine-glycine motif-containing peptides

artículo científico publicado en 2001

Integrin-binding peptides derived from phage display libraries.

artículo científico publicado en 1999

Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library.

artículo científico publicado en 1994

Liquid-chromatographic determination of beta 2-microglobulin, alpha 1-acid glycoprotein, and albumin in urine

artículo científico publicado en 1987

Metabolism and serum binding of RU 486 in women after various single doses.

artículo científico publicado en 1987

Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display

artículo científico publicado en 1998

Novel peptide inhibitors of human kallikrein 2.

artículo científico publicado en 2006

Peptide inhibition of catalytic and noncatalytic activities of matrix metalloproteinase-9 blocks tumor cell migration and invasion.

artículo científico publicado en 2004

Peptide-mediated delivery of therapeutic and imaging agents into mammalian cells.

artículo científico publicado en 2004

Peptides in cell adhesion research

artículo científico publicado en 1994

Peptides in cell adhesion: powerful tools for the study of integrin-ligand interactions.

artículo científico publicado en 1996

Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins

artículo científico publicado en 1995

Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide

scientific article published on 01 January 2005

Reaction of a tumour-associated trypsin inhibitor with serine proteinases associated with coagulation and tumour invasion

artículo científico publicado en 1988

Regulation of cell adhesion: a collaborative effort of integrins, their ligands, cytoplasmic actors, and phosphorylation

artículo científico publicado en 2019

Role of leukemia cell invadosome in extramedullary infiltration

scientific article published on 27 July 2009

Selection of peptides binding to the alpha 5 beta 1 integrin from phage display library.

artículo científico publicado en 1993

Serum samples from pancreatectomized patients contain trypsinogen immunoreactivity

artículo científico publicado en 1996

Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment

artículo científico publicado en 2006

Steps toward mapping the human vasculature by phage display.

artículo científico publicado en 2002

Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens

artículo científico publicado en 2015

Targeting neuropilin-1 in human leukemia and lymphoma

artículo científico publicado en 2011

Targeting of phage display vectors to mammalian cells

artículo científico publicado en 2000

The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation

artículo científico publicado en 2001

Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.

artículo científico publicado en 2017

Time-resolved immunofluorometric assays for trypsinogen-1 and 2 in serum reveal preferential elevation of trypsinogen-2 in pancreatitis

scientific article published on 01 June 1990

Tumor targeting with a selective gelatinase inhibitor

artículo científico publicado en 1999

Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix

artículo científico publicado en 1991

Tumour-associated trypsin inhibitor, TATI. Clinical use and biological function

artículo científico

Use of intein-directed peptide biosynthesis to improve serum stability and bioactivity of a gelatinase inhibitory peptide.

artículo científico publicado en 2003

Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients

artículo científico publicado en 2011

Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction

artículo científico publicado en 2000

Lista de obras de Erkki Koivunen

A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide

A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth

A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins

A polymeric form of fibronectin has antimetastatic effects against multiple tumor types.

A tripeptide mimetic of von Willebrand factor residues 981-983 enhances platelet adhesion to fibrinogen by signaling through integrin alpha(IIb)beta3.

Activation of Type IV Procollagenases by Human Tumor-associated Trypsin-2 ⬇️

Alpha v integrins as receptors for tumor targeting by circulating ligands.

AlphaMbeta2 integrin modulator exerts antitumor activity in vivo

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis

An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.

Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro

Biology and function of tumor-associated trypsin inhibitor, TATI.

Cell-surface association between matrix metalloproteinases and integrins: role of the complexes in leukocyte migration and cancer progression

Cell-surface interactions of echovirus 22.

Characteristics of soluble tumour-derived proteins that inhibit natural killer activity

Characterization of a tumor-associated serine protease

Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells

Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells

Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment

Cyst fluid of ovarian cancer patients contains high concentrations of trypsinogen-2

Design, development, and validation of a high-throughput drug-screening assay for targeting of human leukemia

Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis

Development of novel peptide ligands modulating the enzyme activity of prostate-specific antigen

Down-regulation of trypsinogen-2 expression by chemically modified tetracyclines: association with reduced cancer cell migration

Gelatinase-mediated migration and invasion of cancer cells

Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate

Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen

Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase

Human tongue carcinoma growth is inhibited by selective antigelatinolytic peptides

Identification of a negatively charged peptide motif within the catalytic domain of progelatinases that mediates binding to leukocyte beta 2 integrins

Identification of novel peptide inhibitors for human trypsins.

Identification of novel prostate-specific antigen-binding peptides modulating its enzyme activity.

Identification of receptor ligands with phage display peptide libraries

In vivo localization of gelatinases (MMP-2 and -9) by in situ zymography with a selective gelatinase inhibitor

In vivo targeting of activated leukocytes by a β2-integrin binding peptide

Inhibition of beta(2) integrin-mediated leukocyte cell adhesion by leucine-leucine-glycine motif-containing peptides

Integrin-binding peptides derived from phage display libraries.

Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library.

Liquid-chromatographic determination of beta 2-microglobulin, alpha 1-acid glycoprotein, and albumin in urine

Metabolism and serum binding of RU 486 in women after various single doses.

Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display

Novel peptide inhibitors of human kallikrein 2.

Peptide inhibition of catalytic and noncatalytic activities of matrix metalloproteinase-9 blocks tumor cell migration and invasion.

Peptide-mediated delivery of therapeutic and imaging agents into mammalian cells.

Peptides in cell adhesion research

Peptides in cell adhesion: powerful tools for the study of integrin-ligand interactions.

Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins

Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide

Reaction of a tumour-associated trypsin inhibitor with serine proteinases associated with coagulation and tumour invasion

Regulation of cell adhesion: a collaborative effort of integrins, their ligands, cytoplasmic actors, and phosphorylation

Role of leukemia cell invadosome in extramedullary infiltration

Selection of peptides binding to the alpha 5 beta 1 integrin from phage display library.

Serum samples from pancreatectomized patients contain trypsinogen immunoreactivity

Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment

Steps toward mapping the human vasculature by phage display.

Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens

Targeting neuropilin-1 in human leukemia and lymphoma

Targeting of phage display vectors to mammalian cells

The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation

Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.

Time-resolved immunofluorometric assays for trypsinogen-1 and 2 in serum reveal preferential elevation of trypsinogen-2 in pancreatitis

Tumor targeting with a selective gelatinase inhibitor

Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix

Tumour-associated trypsin inhibitor, TATI. Clinical use and biological function

Use of intein-directed peptide biosynthesis to improve serum stability and bioactivity of a gelatinase inhibitory peptide.

Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients

Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction