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Lista de obras de Nicole M Verrills

A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts.

artículo científico publicado en 2007

A systematic evaluation of the safety and toxicity of fingolimod for its potential use in the treatment of acute myeloid leukaemia.

artículo científico publicado en 2016

Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells.

artículo científico publicado en 2016

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

artículo científico publicado en 2016

Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons.

artículo científico publicado en 2014

Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia

artículo científico publicado en 2006

Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin

artículo científico publicado en 2015

Cell-Free DNA Blood Collection Tubes Are Appropriate for Clinical Proteomics: A Demonstration in Colorectal Cancer.

artículo científico publicado en 2018

Clinical proteomics: present and future prospects.

artículo científico publicado en 2006

Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia"

artículo científico publicado en 2019

Controlling the cell cycle: the role of calcium/calmodulin-stimulated protein kinases I and II.

artículo científico publicado en 2011

Dephosphorylation of CaMKII at T253 controls the metaphase-anaphase transition.

artículo científico publicado en 2014

Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia

artículo científico publicado en 2016

Drug resistance mechanisms in cancer cells: a proteomics perspective.

artículo científico publicado en 2003

Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers

artículo científico publicado en 2010

Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.

artículo científico publicado en 2011

Expression of renin-angiotensin system (RAS) components in endometrial cancer

artículo científico publicado en 2016

FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia

artículo científico publicado en 2007

Functional importance of PP2A regulatory subunit loss in breast cancer

artículo científico publicado en 2017

Harnessing the power of proteomics for identification of oncogenic, druggable signalling pathways in cancer

artículo científico publicado en 2017

Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease.

artículo científico publicado en 2011

Improving the targeting of tubulin-binding agents: lessons from drug resistance studies.

artículo científico publicado en 2005

Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.

artículo científico publicado en 2014

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.

artículo científico

Neuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: role in resistance to microtubule-targeted drugs

scientific article published on 01 September 2004

PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9

artículo científico publicado en 2012

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity

artículo científico publicado en 2015

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity.

artículo científico publicado en 2014

Peripheral Lipopolysaccharide Challenge Induces Long-Term Changes in Tyrosine Hydroxylase Regulation in the Adrenal Medulla.

artículo científico publicado en 2016

Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer

scientific article published on 17 October 2019

Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation

artículo científico publicado en 2010

Proteome analysis of vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations.

artículo científico publicado en 2003

Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia--an in vivo study.

artículo científico publicado en 2006

Quantitative phosphoproteomics uncovers synergy between DNA-PK and FLT3 inhibitors in acute myeloid leukaemia

artículo científico publicado en 2020

Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function.

artículo científico publicado en 2010

Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A.

artículo científico publicado en 2014

Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress

artículo científico publicado el 28 de junio de 2012

TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators.

artículo científico publicado en 2016

Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least Resistance

artículo científico publicado en 2018

Targeting PP2A and proteasome activity ameliorates features of allergic airway disease in mice

artículo científico publicado en 2017

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.

artículo científico publicado en 2013

The microbial proteome database--an automated laboratory catalogue for monitoring protein expression in bacteria

scientific article published on 01 December 1999

The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells

artículo científico publicado en 2016

The proteomics of ageing

artículo científico publicado en 2002

Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition. Novel Role as a Protein Phosphatase 2A Activator.

artículo científico publicado en 2015

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression

artículo científico publicado en 2016