Lista de obras - Daniel F Legler - Dominio Público Uruguay

A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins

artículo científico publicado en 2007

A structure-activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins

artículo científico publicado en 2017

A unique signal sequence of the chemokine receptor CCR7 promotes package into COPII vesicles for efficient receptor trafficking.

artículo científico publicado en 2018

Activation-dependent modulation of B lymphocyte migration to chemokines

scientific article published on 01 September 2000

Analysis of CCR7 mediated T cell transfectant migration using a microfluidic gradient generator

artículo científico publicado en 2015

B cell zone reticular cell microenvironments shape CXCL13 gradient formation

artículo científico publicado en 2020

B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5

artículo científico publicado en 1998

Beyond migration-Chemokines in lymphocyte priming, differentiation, and modulating effector functions

artículo científico publicado en 2018

Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

scientific article published on 13 September 2019

CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation

artículo científico publicado en 2002

CCL19 with CCL21-tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells

artículo científico publicado en 2018

CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2 ⬇️

artículo científico publicado el 30 de octubre de 2003

CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4

artículo científico publicado en 2020

CCR5 deficiency/CCR5Δ32: resistant to HIV infection at the cost of curtailed CD4+ T cell memory responses

artículo científico publicado en 2020

CCR7 Is Recruited to the Immunological Synapse, Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP70

artículo científico publicado en 2018

CCR7: roles in cancer cell dissemination, migration and metastasis formation.

artículo científico publicado en 2014

CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity

artículo científico publicado en 2020

CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems

artículo científico publicado en 2020

Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes

artículo científico publicado en 2001

Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation

scientific article published on 01 October 2019

Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors

artículo científico publicado en 2016

Chemokines: Chemistry, Biochemistry and Biological Function.

artículo científico publicado en 2016

Common and biased signaling pathways of the chemokine receptor CCR7 elicited by its ligands CCL19 and CCL21 in leukocytes.

artículo científico publicado en 2016

Converse regulation of CCR7-driven human dendritic cell migration by prostaglandin E₂ and liver X receptor activation

artículo científico publicado en 2012

Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration

artículo científico publicado en 2011

Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice.

artículo científico publicado en 2010

Differential insertion of GPI-anchored GFPs into lipid rafts of live cells.

artículo científico publicado en 2004

Distinct CCR7 glycosylation pattern shapes receptor signaling and endocytosis to modulate chemotactic responses.

artículo científico publicado en 2016

Distinct modulation of chemokine expression patterns in human monocyte-derived dendritic cells by prostaglandin E(2)

artículo científico publicado en 2012

Distinct motifs in the chemokine receptor CCR7 regulate signal transduction, receptor trafficking and chemotaxis

artículo científico publicado en 2008

Engineering of Nanobodies Recognizing the Human Chemokine Receptor CCR7.

artículo científico publicado en 2019

Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.

artículo científico publicado en 2017

Expression of high- and low-affinity receptors for C3a on the human mast cell line, HMC-1.

artículo científico publicado en 1996

FAT10 localizes in dendritic cell aggresome-like induced structures and contributes to their disassembly

artículo científico publicado en 2020

Fluorescently Tagged CCL19 and CCL21 to Monitor CCR7 and ACKR4 Functions

scientific article published on 04 December 2018

IL-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

scientific article published on 12 February 2019

Identification of CCR8, the receptor for the human CC chemokine I-309

artículo científico publicado en 1997

Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells

artículo científico publicado en 2010

In Vivo Function of the Lipid Raft Protein Flotillin-1 during CD8+ T Cell-Mediated Host Surveillance

artículo científico publicado en 2019

In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity

artículo científico publicado en 2015

Increased mobility of major histocompatibility complex I-peptide complexes decreases the sensitivity of antigen recognition

artículo científico publicado en 2008

Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration

artículo científico publicado en 2016

Interstitial dendritic cell guidance by haptotactic chemokine gradients

artículo científico publicado en 2013

Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity.

artículo científico publicado en 2015

Loss of Gadkin Affects Dendritic Cell Migration In Vitro

artículo científico publicado en 2015

Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics

artículo científico publicado en 2022

Membrane Compartmentalization and Scaffold Proteins in Leukocyte Migration

artículo científico publicado en 2020

Membrane lipid environment: Potential modulation of chemokine receptor function.

artículo científico publicado en 2018

Modulation of Chemokine Receptor Function by Cholesterol: New Prospects for Pharmacological Intervention.

artículo científico publicado en 2017

New insights in chemokine signaling.

artículo científico publicado en 2018

On the move: endocytic trafficking in cell migration.

artículo científico publicado en 2015

Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation.

artículo científico publicado en 2006

Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts

artículo científico publicado en 2005

Preformed reggie/flotillin caps: stable priming platforms for macrodomain assembly in T cells

artículo científico publicado en 2006

Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon

artículo científico publicado en 2008

Prostaglandin E2 at new glance: novel insights in functional diversity offer therapeutic chances.

artículo científico publicado en 2009

Prostaglandin E2 is a key factor for monocyte-derived dendritic cell maturation: enhanced T cell stimulatory capacity despite IDO

scholarly article by Petra Krause et al published 14 August 2007 in Journal of Leukocyte Biology

Prostaglandin E2 is generally required for human dendritic cell migration and exerts its effect via EP2 and EP4 receptors

artículo científico publicado en 2006

Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation

artículo científico publicado en 2003

Regulation of Sec16 levels and dynamics links proliferation and secretion

artículo científico publicado en 2014

Shifting CCR7 towards Its Monomeric Form Augments CCL19 Binding and Uptake

artículo científico publicado en 2022

Soluble major histocompatibility complex-peptide octamers with impaired CD8 binding selectively induce Fas-dependent apoptosis

artículo científico publicado en 2002

TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function.

artículo científico publicado en 1997

The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation

artículo científico publicado en 2003

The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7 ⬇️

artículo científico publicado el 1 de junio de 1998

The dimeric form of CXCL12 binds to atypical chemokine receptor 1

artículo científico publicado en 2021

Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration ⬇️

artículo científico publicado el 13 de julio de 2012

V domain of RAGE interacts with AGEs on prostate carcinoma cells.

artículo científico publicado en 2008

ZAP70 expression enhances chemokine-driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins

artículo científico publicado en 2018

β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4

artículo científico publicado en 2020

Lista de obras de Daniel F Legler

A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins

A structure-activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins

A unique signal sequence of the chemokine receptor CCR7 promotes package into COPII vesicles for efficient receptor trafficking.

Activation-dependent modulation of B lymphocyte migration to chemokines

Analysis of CCR7 mediated T cell transfectant migration using a microfluidic gradient generator

B cell zone reticular cell microenvironments shape CXCL13 gradient formation

B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5

Beyond migration-Chemokines in lymphocyte priming, differentiation, and modulating effector functions

Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation

CCL19 with CCL21-tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells

CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2 ⬇️

CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4

CCR5 deficiency/CCR5Δ32: resistant to HIV infection at the cost of curtailed CD4+ T cell memory responses

CCR7 Is Recruited to the Immunological Synapse, Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP70

CCR7: roles in cancer cell dissemination, migration and metastasis formation.

CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity

CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems

Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes

Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation

Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors

Chemokines: Chemistry, Biochemistry and Biological Function.

Common and biased signaling pathways of the chemokine receptor CCR7 elicited by its ligands CCL19 and CCL21 in leukocytes.

Converse regulation of CCR7-driven human dendritic cell migration by prostaglandin E₂ and liver X receptor activation

Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration

Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice.

Differential insertion of GPI-anchored GFPs into lipid rafts of live cells.

Distinct CCR7 glycosylation pattern shapes receptor signaling and endocytosis to modulate chemotactic responses.

Distinct modulation of chemokine expression patterns in human monocyte-derived dendritic cells by prostaglandin E(2)

Distinct motifs in the chemokine receptor CCR7 regulate signal transduction, receptor trafficking and chemotaxis

Engineering of Nanobodies Recognizing the Human Chemokine Receptor CCR7.

Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.

Expression of high- and low-affinity receptors for C3a on the human mast cell line, HMC-1.

FAT10 localizes in dendritic cell aggresome-like induced structures and contributes to their disassembly

Fluorescently Tagged CCL19 and CCL21 to Monitor CCR7 and ACKR4 Functions

IL-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

Identification of CCR8, the receptor for the human CC chemokine I-309

Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells

In Vivo Function of the Lipid Raft Protein Flotillin-1 during CD8+ T Cell-Mediated Host Surveillance

In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity

Increased mobility of major histocompatibility complex I-peptide complexes decreases the sensitivity of antigen recognition

Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration

Interstitial dendritic cell guidance by haptotactic chemokine gradients

Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity.

Loss of Gadkin Affects Dendritic Cell Migration In Vitro

Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics

Membrane Compartmentalization and Scaffold Proteins in Leukocyte Migration

Membrane lipid environment: Potential modulation of chemokine receptor function.

Modulation of Chemokine Receptor Function by Cholesterol: New Prospects for Pharmacological Intervention.

New insights in chemokine signaling.

On the move: endocytic trafficking in cell migration.

Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation.

Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts

Preformed reggie/flotillin caps: stable priming platforms for macrodomain assembly in T cells

Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon

Prostaglandin E2 at new glance: novel insights in functional diversity offer therapeutic chances.

Prostaglandin E2 is a key factor for monocyte-derived dendritic cell maturation: enhanced T cell stimulatory capacity despite IDO

Prostaglandin E2 is generally required for human dendritic cell migration and exerts its effect via EP2 and EP4 receptors

Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation

Regulation of Sec16 levels and dynamics links proliferation and secretion

Shifting CCR7 towards Its Monomeric Form Augments CCL19 Binding and Uptake

Soluble major histocompatibility complex-peptide octamers with impaired CD8 binding selectively induce Fas-dependent apoptosis

TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function.

The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation

The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7 ⬇️

The dimeric form of CXCL12 binds to atypical chemokine receptor 1

Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration ⬇️

V domain of RAGE interacts with AGEs on prostate carcinoma cells.

ZAP70 expression enhances chemokine-driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins

β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4