Lista de obras - Valentina Bonetto - Dominio Público Uruguay

A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10

artículo científico publicado en 2013

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity

artículo científico publicado en 2013

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

artículo científico publicado en 2009

A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic islets

artículo científico publicado en 2013

Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease

artículo científico publicado en 2003

Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells

artículo científico publicado en 2011

Characterization of antimalarial SPf66 peptide using MALDI-TOF MS, CD and SEC.

artículo científico publicado en 2002

Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis.

artículo científico publicado en 2009

Combination of fast chromatographic separations, biosensor-based functional assays, and mass spectrometry for characterization of complex peptide mixtures.

artículo científico publicado en 1998

Contingent intramuscular boosting of P2XR7 axis improves motor function in transgenic ALS mice

artículo científico publicado en 2021

Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis

artículo científico publicado en 2021

Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis.

artículo científico publicado en 2017

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

artículo científico publicado en 2014

Extracellular Vesicles and a Novel Form of Communication in the Brain

artículo científico publicado en 2016

Extracellular acidification: a novel detection system for ligand/receptor interactions. Demonstration with bioactive peptides and CHO or pancreatic beta cells, but of possible interest for tracing putative receptors in ethanol metabolism

scientific article published on 01 January 1999

Focus on the heterogeneity of amyotrophic lateral sclerosis

artículo científico publicado en 2020

Full-length and N-terminally truncated chicken intestinal diazepam-binding inhibitor

artículo científico publicado en 1997

Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems

artículo científico publicado en 2002

IL-7-induced phosphorylation of the adaptor Crk-like and other targets.

artículo científico publicado en 2018

Insoluble Mutant SOD1 Is Partly Oligoubiquitinated in Amyotrophic Lateral Sclerosis Mice

artículo científico publicado en 2006

Introduction

scientific article published on 01 March 2016

Isolation of peptides from porcine intestinal tissue that induce extracellular acidification in CHO cells: identification of the active peptide as IGF-I and characterization of a fragment of calponin H1 processed at a dibasic site.

artículo científico publicado en 2001

Lack of TNF-alpha receptor type 2 protects motor neurons in a cellular model of amyotrophic lateral sclerosis and in mutant SOD1 mice but does not affect disease progression

artículo científico publicado en 2015

Large-scale HPLC purification of calbindin D9k from porcine intestine

scientific article published on 01 December 1999

Micro-computed tomography for non-invasive evaluation of muscle atrophy in mouse models of disease.

artículo científico publicado en 2018

Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosis

artículo científico publicado en 2013

Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway

artículo científico publicado en 2009

Myosin as a potential redox-sensor: an in vitro study.

artículo científico publicado en 2008

New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models.

artículo científico publicado en 2016

Nitroproteomics of peripheral blood mononuclear cells from patients and a rat model of ALS.

artículo científico publicado en 2009

Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes

artículo científico publicado en 2015

Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse.

artículo científico publicado en 2006

Purification of the aldehyde oxidase homolog 1 (AOH1) protein and cloning of the AOH1 and aldehyde oxidase homolog 2 (AOH2) genes. Identification of a novel molybdo-flavoprotein gene cluster on mouse chromosome 1

scientific journal article

RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.

artículo científico publicado en 2018

Redox proteomics: identification of oxidatively modified proteins.

artículo científico publicado en 2003

Redox regulation of cyclophilin A by glutathionylation.

artículo científico publicado en 2006

Redox regulation of surface protein thiols: identification of integrin alpha-4 as a molecular target by using redox proteomics

artículo científico publicado en 2003

Regulation of redox-sensitive exofacial protein thiols in CHO cells.

artículo científico publicado en 2006

Serological Proteome Analysis (SERPA) as a tool for the identification of new candidate autoantigens in type 1 diabetes

artículo científico publicado en 2013

Synthetic miniprion PrP106.

artículo científico publicado en 2002

Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.

artículo científico publicado en 2016

The molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteins

artículo científico publicado en 2011

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells

artículo científico publicado en 2012

Thiol-disulfide balance: from the concept of oxidative stress to that of redox regulation.

artículo científico publicado en 2005

Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E.

artículo científico publicado en 2012

Lista de obras de Valentina Bonetto

A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic islets

Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease

Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells

Characterization of antimalarial SPf66 peptide using MALDI-TOF MS, CD and SEC.

Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis.

Combination of fast chromatographic separations, biosensor-based functional assays, and mass spectrometry for characterization of complex peptide mixtures.

Contingent intramuscular boosting of P2XR7 axis improves motor function in transgenic ALS mice

Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis

Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis.

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

Extracellular Vesicles and a Novel Form of Communication in the Brain

Extracellular acidification: a novel detection system for ligand/receptor interactions. Demonstration with bioactive peptides and CHO or pancreatic beta cells, but of possible interest for tracing putative receptors in ethanol metabolism

Focus on the heterogeneity of amyotrophic lateral sclerosis

Full-length and N-terminally truncated chicken intestinal diazepam-binding inhibitor

Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems

IL-7-induced phosphorylation of the adaptor Crk-like and other targets.

Insoluble Mutant SOD1 Is Partly Oligoubiquitinated in Amyotrophic Lateral Sclerosis Mice

Introduction

Isolation of peptides from porcine intestinal tissue that induce extracellular acidification in CHO cells: identification of the active peptide as IGF-I and characterization of a fragment of calponin H1 processed at a dibasic site.

Lack of TNF-alpha receptor type 2 protects motor neurons in a cellular model of amyotrophic lateral sclerosis and in mutant SOD1 mice but does not affect disease progression

Large-scale HPLC purification of calbindin D9k from porcine intestine

Micro-computed tomography for non-invasive evaluation of muscle atrophy in mouse models of disease.

Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosis

Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway

Myosin as a potential redox-sensor: an in vitro study.

New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models.

Nitroproteomics of peripheral blood mononuclear cells from patients and a rat model of ALS.

Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes

Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse.

Purification of the aldehyde oxidase homolog 1 (AOH1) protein and cloning of the AOH1 and aldehyde oxidase homolog 2 (AOH2) genes. Identification of a novel molybdo-flavoprotein gene cluster on mouse chromosome 1

RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.

Redox proteomics: identification of oxidatively modified proteins.

Redox regulation of cyclophilin A by glutathionylation.

Redox regulation of surface protein thiols: identification of integrin alpha-4 as a molecular target by using redox proteomics

Regulation of redox-sensitive exofacial protein thiols in CHO cells.

Serological Proteome Analysis (SERPA) as a tool for the identification of new candidate autoantigens in type 1 diabetes

Synthetic miniprion PrP106.

Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.

The molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteins

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells

Thiol-disulfide balance: from the concept of oxidative stress to that of redox regulation.

Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E.