Lista de obras - Chiara Zuccato - Dominio Público Uruguay

A microRNA-based gene dysregulation pathway in Huntington's disease

artículo científico publicado en 2007

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

artículo científico publicado en 2012

Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease

artículo científico publicado en 2008

Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models

artículo científico publicado en 2013

Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347.

artículo científico publicado en 2008

Brain-derived neurotrophic factor in neurodegenerative diseases

artículo científico publicado en 2009

Brain-derived neurotrophic factor in patients with Huntington's disease

artículo científico publicado en 2011

CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice

artículo científico publicado en 2008

Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease

artículo científico publicado en 2007

Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons

artículo científico publicado en 2002

Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain

artículo científico publicado en 2003

Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain

artículo científico publicado en 2005

Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions.

artículo científico publicado en 2007

Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.

artículo científico publicado en 2014

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

artículo científico publicado en 2005

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

artículo científico publicado en 2002

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

artículo científico publicado en 2014

Expressed Alu repeats as a novel, reliable tool for normalization of real-time quantitative RT-PCR data

artículo científico publicado en 2010

Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop

artículo científico publicado en 2014

From target identification to drug screening assays for neurodegenerative diseases

Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease

artículo científico publicado en 2010

Huntingtin gene CAG repeat size affects autism risk: Family-based and case-control association study

artículo científico publicado en 2020

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

artículo científico publicado en 2003

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

artículo científico publicado en 2001

Huntington's disease.

artículo científico publicado en 2014

In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice

artículo científico publicado en 2012

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease

scientific article published on 06 May 2019

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

artículo científico publicado en 2012

Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators

artículo científico publicado en 2007

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

artículo científico publicado en 2001

Loss of normal huntingtin function: new developments in Huntington's disease research

artículo científico publicado en 2001

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease ⬇️

artículo científico publicado el 1 de julio de 2010

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

artículo científico publicado en 2014

NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease

artículo científico publicado en 2012

Normal huntingtin function: an alternative approach to Huntington's disease

artículo científico publicado en 2005

Phylogenetic comparison of huntingtin homologues reveals the appearance of a primitive polyQ in sea urchin

artículo científico publicado en 2007

Pitfalls in the detection of cholesterol in Huntington's disease models

artículo científico publicado en 2012

Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease

artículo científico publicado en 2005

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

artículo científico publicado en 2005

Repressor element-1 silencing transcription factor (REST) is present in human control and Huntington's disease neurones

artículo científico publicado en 2014

Role of brain-derived neurotrophic factor in Huntington's disease

artículo científico publicado en 2007

Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington's disease mutation in peripheral lymphocytes.

artículo científico publicado en 2007

Shc3 affects human high-grade astrocytomas survival

artículo científico publicado en 2005

Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease

artículo científico publicado en 2007

The Huntington's Paradox

artículo científico publicado en 2016

The enigma of Huntington's disease.

artículo científico publicado en 2002

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

artículo científico publicado en 2012

The function of the neuronal proteins Shc and huntingtin in stem cells and neurons: pharmacologic exploitation for human brain diseases

artículo científico publicado en 2005

The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease

scientific article published on 17 February 2010

Turning REST/NRSF dysfunction in Huntington's disease into a pharmaceutical target

artículo científico publicado en 2009

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

artículo científico publicado en 2007

Lista de obras de Chiara Zuccato

A microRNA-based gene dysregulation pathway in Huntington's disease

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease

Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models

Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347.

Brain-derived neurotrophic factor in neurodegenerative diseases

Brain-derived neurotrophic factor in patients with Huntington's disease

CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice

Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease

Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons

Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain

Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain

Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions.

Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

Expressed Alu repeats as a novel, reliable tool for normalization of real-time quantitative RT-PCR data

Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop

From target identification to drug screening assays for neurodegenerative diseases

Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease

Huntingtin gene CAG repeat size affects autism risk: Family-based and case-control association study

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

Huntington's disease.

In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

Loss of normal huntingtin function: new developments in Huntington's disease research

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease ⬇️

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease

Normal huntingtin function: an alternative approach to Huntington's disease

Phylogenetic comparison of huntingtin homologues reveals the appearance of a primitive polyQ in sea urchin

Pitfalls in the detection of cholesterol in Huntington's disease models

Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

Repressor element-1 silencing transcription factor (REST) is present in human control and Huntington's disease neurones

Role of brain-derived neurotrophic factor in Huntington's disease

Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington's disease mutation in peripheral lymphocytes.

Shc3 affects human high-grade astrocytomas survival

Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease

The Huntington's Paradox

The enigma of Huntington's disease.

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

The function of the neuronal proteins Shc and huntingtin in stem cells and neurons: pharmacologic exploitation for human brain diseases

The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease

Turning REST/NRSF dysfunction in Huntington's disease into a pharmaceutical target

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.