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Lista de obras de Roberto Di Santo

(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies

artículo científico publicado en 2015

1-Arylsulfonyl-3-(α-hydroxybenzyl)-1H-pyrroles, a novel class of anti-HIV-1 reverse transcriptase inhibitors

artículo científico

2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays

artículo científico publicado en 2004

2H-Pyrrolo[3,4-b] [1,5]benzothiazepine derivatives as potential inhibitors of HIV-1 reverse transcriptase

artículo científico publicado en 2005

6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach

artículo científico publicado en 2013

6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro

artículo científico publicado en 2005

6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays

artículo científico publicado en 2004

A rational approach to predict and modulate stereolability of chiral alpha substituted ketones

artículo científico publicado en 2009

Activity of caffeic acid derivatives against Candida albicans biofilm.

artículo científico publicado en 2014

Antifungal agents. 10. New derivatives of 1-[(aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-candida activity, and quantitative structure-analysis relationship studies

artículo científico publicado en 2002

Antifungal agents. 11. N-substituted derivatives of 1-[(aryl)(4-aryl-1H-pyrrol-3-yl)methyl]-1H-imidazole: synthesis, anti-Candida activity, and QSAR studies

artículo científico publicado en 2005

Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies.

artículo científico publicado en 2000

Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 1).

artículo científico publicado en 2006

Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 2).

artículo científico publicado en 2006

Basic quinolinonyl diketo acid derivatives as inhibitors of HIV integrase and their activity against RNase H function of reverse transcriptase

artículo científico publicado en 2014

Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.

artículo científico publicado en 2016

Cinnamoyl Compounds as Simple Molecules that Inhibit p300 Histone Acetyltransferase

artículo científico publicado en 2007

Comparison of different methods for the extraction of cannabinoids from cannabis

scientific article published on 29 April 2019

Competing sigmatropic shift rearrangements in excited allyl radicals.

artículo científico publicado en 2008

Convenient Route to 2H-Pyrrolo[3,4-b]quinolin-9(4H)-one Skeleton via TosMIC Reaction

Conversion of a racemic mixture of 8-chloro-2-(2,6-difluorophenylmethyl)-2,3-dihydro-3-methyl-1,2,5-benzothiadiazepin-4(5h)-one 1,1-dioxide into a single enantiomer via a chromatographic resolution/racemization method.

artículo científico publicado en 2003

Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents

artículo científico publicado en 2019

Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors

artículo científico publicado en 2002

Design, synthesis and evaluation of 3,4-dihydroxybenzoic acid derivatives as antioxidants, bio-metal chelating agents and acetylcholinesterase inhibitors

artículo científico publicado en 2014

Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors

artículo científico publicado en 2005

Design, synthesis, and structure-activity relationship of N-arylnaphthylamine derivatives as amyloid aggregation inhibitors

artículo científico publicado en 2012

Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors

artículo científico publicado en 2006

Development of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compounds

artículo científico publicado en 2006

Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4

artículo científico publicado en 2016

Diketo Acids Derivatives as Dual Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and the Reverse Transcriptase RNase H Domain

artículo científico publicado el 1 de enero de 2011

Diketo hexenoic acid derivatives are novel selective non-nucleoside inhibitors of mammalian terminal deoxynucleotidyl transferases, with potent cytotoxic effect against leukemic cells

artículo científico publicado en 2005

Discovery and Pharmacological Profile of New 1H-Indazole-3-carboxamide and 2H-Pyrrolo[3,4-c]quinoline Derivatives as Selective Serotonin 4 Receptor Ligands

artículo científico publicado en 2012

Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75.

artículo científico publicado en 2015

Discovery of in vitro antitubercular agents through in silico ligand-based approaches.

artículo científico publicado en 2016

Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action

artículo científico publicado en 2012

Enantioselective liquid chromatography of C3-chiral 2,3-dihydro-1,2,5-benzothiadiazepin-4(5H)-one and thione 1,1-dioxides on polyacrylamide- and polysaccharide-based chiral stationary phases

artículo científico publicado el 18 de abril de 2003

Evaluation of HIV-1 integrase inhibitors on human primary macrophages using a luciferase-based single-cycle phenotypic assay.

artículo científico publicado en 2010

Evaluation of the Anti-<i>Histoplasma capsulatum</i> Activity of Indole and Nitrofuran Derivatives and Their Pharmacological Safety in Three-Dimensional Cell Cultures

scientific article published on 12 May 2022

Exploring the anti-biofilm activity of cinnamic acid derivatives in Candida albicans.

artículo científico publicado en 2016

Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.

artículo científico publicado en 1998

HIV-1 RT-Associated RNase H Function Inhibitors: Recent Advances in Drug Development

artículo científico publicado el 1 de enero de 2010

HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein

artículo científico publicado en 2007

Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection

artículo científico publicado en 2008

Human terminal deoxynucleotidyl transferases as novel targets for anticancer chemotherapy

artículo científico publicado en 2006

Hypoglycemic activity of curcumin synthetic analogues in alloxan-induced diabetic rats

artículo científico publicado en 2015

Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells

artículo científico publicado en 2012

Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives

artículo científico publicado en 2014

In Vitro Antiviral Activity of New Oxazoline Derivatives as Potent Poliovirus Inhibitors

scientific article published on 18 December 2018

Inhibiting the HIV integration process: past, present, and the future.

artículo científico publicado en 2013

Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives

artículo científico publicado en 2017

Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties.

artículo científico publicado en 2017

In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51.

artículo científico publicado en 2016

Molecular Modeling of Azole Antifungal Agents Active againstCandida albicans. 1. A Comparative Molecular Field Analysis Study1

scientific article published on 01 March 1996

N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase

artículo científico publicado en 2015

Natural products as antifungal agents against clinically relevant pathogens

artículo científico publicado en 2010

New N,N-dimethylcarbamate inhibitors of acetylcholinesterase: design synthesis and biological evaluation

artículo científico publicado en 2016

New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi

artículo científico publicado en 2013

New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H.

artículo científico publicado en 2016

New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target

artículo científico publicado en 2013

New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation

artículo científico publicado en 2017

Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity

artículo científico publicado en 2011

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity

scientific article published on 30 July 2018

Novel Symmetrical Benzazolyl Derivatives Endowed with Potent anti-Heparanase Activity

artículo científico publicado en 2018

Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action

artículo científico publicado en 2006

Novel quinolinonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, and biological activities

artículo científico publicado en 2008

Perturbing Effects of Chiral Stationary Phase on Enantiomerization Second-Order Rate Constants Determined by Enantioselective Dynamic High-Performance Liquid Chromatography: A Practical Tool to Quantify the Accessible Acid and Basic Catalytic Sites B

artículo científico publicado en 2009

Pharmacophore Assessment Through 3-D QSAR: Evaluation of the Predictive Ability on New Derivatives by the Application on a Series of Antitubercular Agents

artículo científico publicado en 2013

Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin topoisomerase I (Top1) inhibitors

artículo científico publicado en 2013

Probing HIV-1 Integrase Inhibitor Binding Sites with Position-Specific Integrase-DNA Cross-Linking Assays

article

Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis.

artículo científico publicado en 1998

Research on nitrogen containing heterocyclic compounds.XX. Synthesis of 8H-Imidazo[5,1-c]pyrrolo[1,2-a][1,4]benzodiazepine and its 6-derivatives

article published in 1993

Salmonella enterica serovar Typhimurium growth is inhibited by the concomitant binding of Zn(II) and a pyrrolyl-hydroxamate to ZnuA, the soluble component of the ZnuABC transporter

artículo científico publicado en 2016

Searching for new agents active against Candida albicans biofilm: A series of indole derivatives, design, synthesis and biological evaluation

artículo científico publicado en 2019

Simple but highly effective three-dimensional chemical-feature-based pharmacophore model for diketo acid derivatives as hepatitis C virus RNA-dependent RNA polymerase inhibitors

artículo científico publicado en 2005

Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma cruzi Sterol 14α-Demethylase: Two Regions of the Enzyme Molecule Potentiate Its Inhibition

artículo científico publicado en 2014

Structure-Activity Relationships on Cinnamoyl Derivatives as Inhibitors of p300 Histone Acetyltransferase.

artículo científico publicado en 2017

Structure-activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain

artículo científico publicado en 2015

Structure-guided approach identifies a novel class of HIV-1 ribonuclease H inhibitors: binding mode insights through magnesium complexation and site-directed mutagenesis studies

article

Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives

artículo científico publicado en 2012

Synthesis and cerebral uptake of 1-(1-[(11)C]methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A.

artículo científico publicado en 2008

Synthesis, biological evaluation and structure-activity correlation study of a series of imidazol-based compounds as Candida albicans inhibitors

artículo científico publicado en 2014

The first potent diphenyl phosphonate KLK4 inhibitors with unexpected binding kinetics

Towards a new application of amaranth seed oil as an agent against Candida albicans

scientific article published on 04 December 2019

Will Integrase Inhibitors be Used as Microbicides?

artículo científico publicado el 1 de enero de 2012