Lista de obras - Susan K. Murphy - Dominio Público Uruguay

450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy

artículo científico publicado en 2012

A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line.

artículo científico publicado en 2014

Abnormal postnatal maintenance of elevated DLK1 transcript levels in callipyge sheep.

artículo científico publicado en 2005

Acquisition of a side population fraction augments malignant phenotype in ovarian cancer

scientific article published on 02 October 2019

An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa

artículo científico publicado en 2002

Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring

artículo científico publicado en 2013

Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer.

artículo científico publicado en 2013

Associations between prenatal physical activity, birth weight, and DNA methylation at genomically imprinted domains in a multiethnic newborn cohort

artículo científico publicado en 2015

Bisulfite pyrosequencing

scientific article published on 01 January 2013

Bisulfite sequencing of cloned alleles.

artículo científico publicado en 2013

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

artículo científico

Callipyge mutation affects gene expression in cis: a potential role for chromatin structure.

artículo científico publicado en 2006

Cannabinoid exposure and altered DNA methylation in rat and human sperm

artículo científico publicado en 2018

Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm

scientific article published on 26 August 2019

Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer

artículo científico publicado en 2015

Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions

artículo científico publicado en 2022

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

artículo científico publicado en 2017

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

scientific article published on 19 September 2019

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica

artículo científico publicado en 2012

DNA methylation at imprint regulatory regions in preterm birth and infection.

artículo científico publicado en 2013

DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination

artículo científico publicado en 2012

Dasatinib (BMS-35482) has synergistic activity with paclitaxel and carboplatin in ovarian cancer cells.

artículo científico publicado en 2011

Dasatinib (BMS-35482) interacts synergistically with docetaxel, gemcitabine, topotecan, and doxorubicin in ovarian cancer cells with high SRC pathway activation and protein expression

artículo científico publicado en 2014

Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements ⬇️

artículo científico publicado el 1 de julio de 2012

Differential Angiogenic Gene Expression in TP53 Wild-Type and Mutant Ovarian Cancer Cell Lines

artículo científico publicado en 2014

Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues.

artículo científico publicado en 2012

Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes.

artículo científico publicado en 2016

Distribution of HPV genotypes in cervical intraepithelial lesions and cervical cancer in Tanzanian women

artículo científico publicado en 2011

Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms

artículo científico publicado en 2020

Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer.

artículo científico publicado en 2010

Epigenetic Regulation of Claudin-1 in the Development of Ovarian Cancer Recurrence and Drug Resistance

artículo científico publicado en 2021

Epigenetic and genetic dispositions of ovarian carcinomas

artículo científico publicado en 2014

Epigenetic detection of human chromosome 14 uniparental disomy

scientific article published on 01 July 2003

Epigenetic determinants of ovarian clear cell carcinoma biology.

artículo científico publicado en 2014

Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

artículo científico publicado en 2010

Epigenome-wide meta-analysis of DNA methylation and childhood asthma

artículo científico publicado en 2018

Establishment of a Novel Histopathological Classification of High-Grade Serous Ovarian Carcinoma Correlated with Prognostically Distinct Gene Expression Subtypes

artículo científico publicado en 2016

Expression signatures of TP53 mutations in serous ovarian cancers

artículo científico publicado en 2010

Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST).

artículo científico publicado en 2011

Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer

scientific article published on 01 April 2006

GPR54 is a target for suppression of metastasis in endometrial cancer

artículo científico publicado en 2011

Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke ⬇️

artículo científico publicado el 20 de diciembre de 2011

Genome nucleotide lengths that are divisible by six are not essential but enhance replication of defective interfering RNAs of the paramyxovirus simian virus 5.

artículo científico publicado en 1997

Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

artículo científico publicado en 2009

Genomic sweeping for hypermethylated genes

artículo científico publicado en 2006

Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression

artículo científico

HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA

artículo científico publicado en 2014

Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.

artículo científico publicado en 2013

Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma

artículo científico publicado en 2013

High poly(adenosine diphosphate-ribose) polymerase expression and poor survival in advanced-stage serous ovarian cancer

artículo científico publicado en 2010

IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites ⬇️

artículo científico publicado el 1 de enero de 2012

Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes.

artículo científico publicado en 2010

Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals.

artículo científico publicado en 2002

Imprint regulatory elements as epigenetic biosensors of exposure in epidemiological studies.

artículo científico publicado en 2009

Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation

artículo científico publicado en 2007

Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury

artículo científico publicado en 2014

Imprinting evolution and the price of silence.

artículo científico publicado en 2003

Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy

artículo científico publicado en 2009

Increased Intragenic IGF2 Methylation is Associated with Repression of Insulator Activity and Elevated Expression in Serous Ovarian Carcinoma

artículo científico publicado en 2013

Insulin-like growth factor 2/H19 methylation at birth and risk of overweight and obesity in children

artículo científico publicado en 2012

Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta

scientific article published on 28 November 2014

Investigating Epigenetic Effects of Prenatal Exposure to Toxic Metals in Newborns: Challenges and Benefits

artículo científico publicado en 2014

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

scientific article published on 29 March 2019

Loss of betaglycan expression in ovarian cancer: role in motility and invasion

artículo científico publicado en 2007

MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition.

scientific article published on July 2009

Main principles and outcomes of DNA methylation analysis.

artículo científico publicado en 2013

Maternal BMI, IGF-I Levels, and Birth Weight in African American and White Infants

artículo científico publicado en 2013

Maternal inflammatory diet and adverse pregnancy outcomes: Circulating cytokines and genomic imprinting as potential regulators?

artículo científico publicado en 2017

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study

scientific article published on 26 March 2019

Menstrual cyclic change of metastin/GPR54 in endometrium

scientific article published on 08 June 2014

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

article

Methylation-specific PCR

artículo científico publicado en 2013

Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome

artículo científico publicado en 2009

Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example

artículo científico publicado en 2016

Newborns of obese parents have altered DNA methylation patterns at imprinted genes.

artículo científico publicado en 2013

Novel retrotransposed imprinted locus identified at human 6p25 ⬇️

artículo científico publicado el 18 de marzo de 2011

Obesity: Paternal obesity--a risk factor for autism?

artículo científico publicado en 2014

Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype

artículo científico publicado en 2009

PEG1/MEST and IGF2 DNA methylation in CIN and in cervical cancer.

artículo científico publicado en 2013

Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort

artículo científico publicado en 2013

Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers.

artículo científico publicado en 2005

Prenatal sensitization of a postnatal trigger for metabolic disease.

artículo científico publicado en 2013

Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer.

artículo científico publicado en 2011

RNA replication from the simian virus 5 antigenomic promoter requires three sequence-dependent elements separated by sequence-independent spacer regions

artículo científico publicado en 2001

Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease

artículo científico publicado en 2013

Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth

artículo científico publicado en 2020

STAT1 drives tumor progression in serous papillary endometrial cancer.

artículo científico publicado en 2014

Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling.

artículo científico publicado en 2010

Stress affects uterine receptivity through an ovarian-independent pathway.

artículo científico publicado en 2008

Stress: a possible link between genetics, epigenetics, and childhood asthma

artículo científico publicado en 2013

Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer

artículo científico publicado en 2016

Targeting dormant ovarian cancer cells in vitro and in an in vivo mouse model of platinum resistance

scientific article published on 09 October 2020

Targeting ovarian cancer-initiating cells

scientific article published on February 2010

Targeting slow-proliferating ovarian cancer cells.

artículo científico publicado en 2010

Targeting the epigenome in ovarian cancer.

artículo científico

The BMP signaling pathway leads to enhanced proliferation in serous ovarian cancer-A potential therapeutic target.

artículo científico publicado en 2015

The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer

artículo científico publicado en 2011

The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring.

artículo científico publicado en 2011

The regulation of MASPIN expression in epithelial ovarian cancer: association with p53 status, and MASPIN promoter methylation: a gynecologic oncology group study.

artículo científico publicado en 2011

Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk.

artículo científico publicado en 2005

Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer.

artículo científico publicado en 2007

Trophinin is a potent prognostic marker of ovarian cancer involved in platinum sensitivity

scientific article published on 19 June 2007

Utilization of genomic signatures to identify high-efficacy candidate drugs for chemorefractory endometrial cancers

artículo científico publicado en 2013

Validation of ovarian cancer gene expression signatures for survival and subtype in formalin fixed paraffin embedded tissues ⬇️

artículo científico publicado el 26 de diciembre de 2012

Yin yang 1 modulates taxane response in epithelial ovarian cancer

artículo científico publicado en 2009

Lista de obras de Susan K. Murphy

450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy

A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line.

Abnormal postnatal maintenance of elevated DLK1 transcript levels in callipyge sheep.

Acquisition of a side population fraction augments malignant phenotype in ovarian cancer

An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa

Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring

Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer.

Associations between prenatal physical activity, birth weight, and DNA methylation at genomically imprinted domains in a multiethnic newborn cohort

Bisulfite pyrosequencing

Bisulfite sequencing of cloned alleles.

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Callipyge mutation affects gene expression in cis: a potential role for chromatin structure.

Cannabinoid exposure and altered DNA methylation in rat and human sperm

Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm

Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer

Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica

DNA methylation at imprint regulatory regions in preterm birth and infection.

DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination

Dasatinib (BMS-35482) has synergistic activity with paclitaxel and carboplatin in ovarian cancer cells.

Dasatinib (BMS-35482) interacts synergistically with docetaxel, gemcitabine, topotecan, and doxorubicin in ovarian cancer cells with high SRC pathway activation and protein expression

Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements ⬇️

Differential Angiogenic Gene Expression in TP53 Wild-Type and Mutant Ovarian Cancer Cell Lines

Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues.

Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes.

Distribution of HPV genotypes in cervical intraepithelial lesions and cervical cancer in Tanzanian women

Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms

Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer.

Epigenetic Regulation of Claudin-1 in the Development of Ovarian Cancer Recurrence and Drug Resistance

Epigenetic and genetic dispositions of ovarian carcinomas

Epigenetic detection of human chromosome 14 uniparental disomy

Epigenetic determinants of ovarian clear cell carcinoma biology.

Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

Epigenome-wide meta-analysis of DNA methylation and childhood asthma

Establishment of a Novel Histopathological Classification of High-Grade Serous Ovarian Carcinoma Correlated with Prognostically Distinct Gene Expression Subtypes

Expression signatures of TP53 mutations in serous ovarian cancers

Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST).

Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer

GPR54 is a target for suppression of metastasis in endometrial cancer

Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke ⬇️

Genome nucleotide lengths that are divisible by six are not essential but enhance replication of defective interfering RNAs of the paramyxovirus simian virus 5.

Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

Genomic sweeping for hypermethylated genes

Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression

HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA

Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.

Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma

High poly(adenosine diphosphate-ribose) polymerase expression and poor survival in advanced-stage serous ovarian cancer

IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites ⬇️

Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes.

Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals.

Imprint regulatory elements as epigenetic biosensors of exposure in epidemiological studies.

Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation

Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury

Imprinting evolution and the price of silence.

Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy

Increased Intragenic IGF2 Methylation is Associated with Repression of Insulator Activity and Elevated Expression in Serous Ovarian Carcinoma

Insulin-like growth factor 2/H19 methylation at birth and risk of overweight and obesity in children

Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta

Investigating Epigenetic Effects of Prenatal Exposure to Toxic Metals in Newborns: Challenges and Benefits

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

Loss of betaglycan expression in ovarian cancer: role in motility and invasion

MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition.

Main principles and outcomes of DNA methylation analysis.

Maternal BMI, IGF-I Levels, and Birth Weight in African American and White Infants

Maternal inflammatory diet and adverse pregnancy outcomes: Circulating cytokines and genomic imprinting as potential regulators?

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study

Menstrual cyclic change of metastin/GPR54 in endometrium

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Methylation-specific PCR

Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome

Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example

Newborns of obese parents have altered DNA methylation patterns at imprinted genes.

Novel retrotransposed imprinted locus identified at human 6p25 ⬇️

Obesity: Paternal obesity--a risk factor for autism?

Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype

PEG1/MEST and IGF2 DNA methylation in CIN and in cervical cancer.