Lista de obras - Deborah Mash - Dominio Público Uruguay

A Common DIO2 Polymorphism And Alzheimer's Disease Dementia in African And European Americans.

artículo científico publicado en 2018

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease

artículo científico publicado en 2007

A review of brain biorepository management and operations

article

ATP13A2 variability in Parkinson disease.

scientific article published on March 2009

Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease

artículo científico publicado en 2014

Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities

artículo científico publicado en 1996

Alpha synuclein protein levels are increased in serum from recently abstinent cocaine abusers

artículo científico publicado en 2007

Alpha-synuclein aggregation and its relation to neurodegenerative diseases

artículo científico publicado en 2005

Altered Dopamine Synaptic Markers in Postmortem Brain of Obese Subjects.

artículo científico publicado en 2017

Alzheimer disease (AD) specific transcription, DNA methylation and splicing in twenty AD associated loci

artículo científico publicado en 2015

An evaluation of the impact of MAPT, SNCA and APOE on the burden of Alzheimer's and Lewy body pathology

artículo científico publicado en 2012

Assessment of stress markers in restrained individuals following physical stress with and without sham CED activation

scientific article published on 26 June 2020

Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis

scientific article published on 01 November 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Beyond Guam: the cyanobacteria/BMAA hypothesis of the cause of ALS and other neurodegenerative diseases

artículo científico publicado en 2009

BisQC: an operational pipeline for multiplexed bisulfite sequencing

artículo científico publicado en 2014

Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics.

artículo científico publicado en 2003

Brain biomarkers for identifying excited delirium as a cause of sudden death

artículo científico publicado en 2009

Breaking the cycle of opioid use disorder with Ibogaine

artículo científico publicado en 2017

CNVs in neurodevelopmental disorders

artículo científico publicado en 2015

CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit.

artículo científico publicado en 2016

Cause, seasonality of death and co-morbidities in progressive supranuclear palsy (PSP).

artículo científico publicado en 2005

Causes of death in multiple system atrophy

artículo científico publicado en 2007

Cerebral uptake and protein incorporation of cyanobacterial toxin β-N-methylamino-L-alanine

artículo científico publicado en 2013

Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum.

artículo científico publicado en 2004

Clinical Heterogeneity of the LRRK2 G2019S Mutation

Cocaine abuse elevates alpha-synuclein and dopamine transporter levels in the human striatum

artículo científico publicado en 2005

Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons.

artículo científico publicado en 2003

Cocaine promotes primary human astrocyte proliferation via JNK-dependent up-regulation of cyclin A2.

artículo científico publicado en 2016

Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates

artículo científico publicado en 2005

Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster

artículo científico publicado en 2020

Commentary on: Johnson MM, David JA, Michelhaugh SK, Schmidt CJ, Bannon MJ. Increased heat shock protein 70 gene expression in the brains of cocaine-related fatalities may be reflective of postdrug survival and intervention rather than excited delir

artículo científico publicado en 2013

Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo

artículo científico publicado en 2006

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

artículo científico publicado en 2011

Correction: Somatic mtDNA Mutation Spectra in the Aging Human Putamen.

artículo científico publicado en 2013

Correlating human and animal studies of cocaine abuse and gene expression.

artículo científico publicado en 2008

Corrigendum to "Determinants of denervation-independent depletion of putamen dopamine in Parkinson's disease and multiple system atrophy" [Parkinsonism Relat. Disord. 35 (2017) 88-91]

artículo científico publicado en 2017

Cortical and amygdalar Lewy body burden in Parkinson's disease patients with visual hallucinations

artículo científico publicado en 2005

Criteria for the interpretation of cocaine levels in human biological samples and their relation to the cause of death

artículo científico publicado en 2004

Cyanobacterial Neurotoxin BMAA and Mercury in Sharks

artículo científico publicado en 2016

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-l-alanine (BMAA), in South Florida aquatic food webs ⬇️

artículo científico publicado el 1 de septiembre de 2010

Cyanobacterial neurotoxin BMAA and brain pathology in stranded dolphins

scientific article published on 20 March 2019

Cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) in shark fins

artículo científico publicado en 2012

DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects

artículo científico publicado en 2017

Decreased expression of the transcription factor NURR1 in dopamine neurons of cocaine abusers

artículo científico publicado en 2002

Decreased vesicular storage and aldehyde dehydrogenase activity in multiple system atrophy

artículo científico publicado en 2015

Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration.

artículo científico publicado en 2015

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

artículo científico publicado en 2013

Determinants of denervation-independent depletion of putamen dopamine in Parkinson's disease and multiple system atrophy.

artículo científico publicado en 2016

Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain

artículo científico publicado en 2016

Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay

artículo científico publicado en 2004

Disparities in death certificates of Parkinson's disease patients: a report from a population of brain donors

artículo científico publicado en 2006

Do vervets and macaques respond differently to BMAA?

artículo científico publicado en 2016

Does cigarette smoking provide clinically significant neuroprotection among patients diagnosed with Parkinson's disease?

artículo científico publicado en 2005

Dopamine transport function is elevated in cocaine users

artículo científico publicado en 2002

Dopaminergic innervation of the human striatum in Parkinson's disease

artículo científico publicado en 2007

Dynamics of hippocampal neurogenesis in adult humans

artículo científico publicado en 2013

EXCITATION study: Unexplained in-custody deaths: Evaluating biomarkers of stress and agitation

artículo científico publicado en 2019

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

artículo científico publicado en 2014

Environmental neurotoxins β-N-methylamino-l-alanine (BMAA) and mercury in shark cartilage dietary supplements

artículo científico publicado en 2014

Excited Delirium Syndrome (ExDS): Defining Based on a Review of the Literature ⬇️

artículo científico publicado el 25 de marzo de 2011

Excited Delirium and Sudden Death: A Syndromal Disorder at the Extreme End of the Neuropsychiatric Continuum

artículo científico publicado en 2016

Expression of alpha-synuclein mRNA in Parkinson's disease

artículo científico publicado en 2007

FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression

artículo científico publicado en 2009

Family history of dementia: dementia with lewy bodies and dementia in Parkinson's disease

artículo científico publicado en 2006

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models

artículo científico publicado en 2014

GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats

artículo científico publicado en 2012

GCH1 expression in human cerebellum from healthy individuals is not gender dependent

scientific article published on 30 June 2009

Galanin receptor over-expression within the amygdala in early Alzheimer's disease: an in vitro autoradiographic analysis

artículo científico publicado en 2002

Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder

artículo científico publicado en 2017

Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling

artículo científico publicado en 2007

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

artículo científico publicado en 2016

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genetic variation in human NPY expression affects stress response and emotion

artículo científico publicado en 2008

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

artículo científico publicado en 2014

Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease

scientific article published on 24 June 2019

Glucocerebrosidase mutations in diffuse Lewy body disease

artículo científico publicado en 2011

Glucosidase-beta variations and Lewy body disorders

artículo científico publicado en 2008

Hallucinations in multiple system atrophy

artículo científico publicado en 2006

Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution

artículo científico publicado en 2008

Human Serotonin Transporter Coding Variation Establishes Conformational Bias with Functional Consequences

artículo científico publicado en 2019

Hypothesizing Las Vegas and Sutherland Springs Mass Shooters Suffer from Reward Deficiency Syndrome: "Born Bad"

artículo científico publicado en 2017

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes.

artículo científico publicado en 2018

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes

artículo científico publicado en 2003

Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases

artículo científico publicado en 2013

Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach

artículo científico publicado en 2011

Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment

artículo científico publicado en 2008

Insular pathology in Parkinson's disease patients with orthostatic hypotension

artículo científico publicado en 2006

Integrated whole transcriptome and DNA methylation analysis identifies gene networks specific to late-onset Alzheimer's disease

artículo científico publicado en 2015

Intronic Polymorphisms Affecting Alternative Splicing of Human Dopamine D2 Receptor Are Associated with Cocaine Abuse ⬇️

artículo científico publicado el 8 de diciembre de 2010

Localization of muscarinic receptor subtypes in brain stem areas regulating sleep

artículo científico publicado en 1994

Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease

artículo científico publicado en 2006

Lrrk2 and Lewy body disease

artículo científico publicado en 2006

MDMA self-administration in rats: acquisition, progressive ratio responding and serotonin transporter binding

artículo científico publicado en 2007

Markers for dopaminergic neurotransmission in the cerebellum in normal individuals and patients with Parkinson's disease examined by RT-PCR.

artículo científico publicado en 2003

Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependencea

Melatonin MT1 and MT2 receptor expression in Parkinson's disease

artículo científico publicado en 2010

Molecular profiling of midbrain dopamine regions in cocaine overdose victims ⬇️

artículo científico publicado el 1 de mayo de 2003

Multiregional gene expression profiling identifies MRPS6 as a possible candidate gene for Parkinson's disease

artículo científico publicado en 2006

National Association of Medical Examiners position paper on the certification of cocaine-related deaths

artículo científico publicado en 2004

Natural history of progressive supranuclear palsy: a clinicopathologic study from a population of brain donors

artículo científico publicado en 2005

Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment

artículo científico publicado en 2003

Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms

artículo científico publicado en 2010

Norepinephrine transporter immunoblotting and radioligand binding in cocaine abusers

artículo científico publicado en 2005

Noribogaine is a G-protein biased κ-opioid receptor agonist

artículo científico publicado en 2015

Noribogaine reduces nicotine self-administration in rats

artículo científico publicado en 2015

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

artículo científico publicado en 2012

Oral noribogaine shows high brain uptake and anti-withdrawal effects not associated with place preference in rodents.

artículo científico publicado en 2016

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

artículo científico publicado en 2015

Phenotypic associations of tau and ApoE in Parkinson's disease

artículo científico publicado en 2007

Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes

artículo científico publicado en 2015

Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy

artículo científico publicado en 2007

RIG-1 receptor expression in the pathology of Alzheimer's disease

scientific article published on 02 April 2014

RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles

artículo científico publicado en 2015

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

artículo científico publicado en 2015

Reading LINEs within the cocaine addicted brain

artículo científico publicado en 2017

Reduced LRRK2 in association with retromer dysfunction in post-mortem brain tissue from LRRK2 mutation carriers

artículo científico publicado en 2017

Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics.

artículo científico publicado en 2002

Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians

artículo científico publicado en 2012

Response of rats to low levels of sarin.

artículo científico publicado en 2002

Restriction Enzyme Based Enriched L1Hs Sequencing (REBELseq): A Scalable Technique for Detection of Ta Subfamily L1Hs in the Human Genome

artículo científico publicado en 2020

Robust single-cell DNA methylome profiling with snmC-seq2

artículo científico publicado en 2018

Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain

artículo científico publicado en 2003

Somatic mtDNA mutation spectra in the aging human putamen

artículo científico publicado en 2013

Species and cell-type properties of classically defined human and rodent neurons and glia

artículo científico publicado en 2018

Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol

artículo científico publicado en 2011

THE HUMAN BRAINOME: HUMAN BRAIN GENOME, TRANSCRIPTOME, AND PROTEOME INTEGRATION

The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target

The natural non-protein amino acid N-β-methylamino-L-alanine (BMAA) is incorporated into protein during synthesis

artículo científico publicado en 2014

The neurochemical mechanism of rebound psychosis in Parkinson's disease

artículo científico publicado en 2005

The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients.

artículo científico publicado en 2011

The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human

artículo científico publicado en 2012

Thinning of the arterial media layer as a possible preclinical stage in HIV vasculopathy: a pilot study

scientific article published on 22 December 2011

Visual hallucinations in progressive supranuclear palsy

scientific article published on 01 January 2005

Vitamin D receptor and Alzheimer's disease: a genetic and functional study

artículo científico publicado en 2012

Zhou et al. reply

scientific article published in Nature

l-Serine Reduces Spinal Cord Pathology in a Vervet Model of Preclinical ALS/MND

artículo científico publicado en 2020

Lista de obras de Deborah Mash

A Common DIO2 Polymorphism And Alzheimer's Disease Dementia in African And European Americans.

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease

A review of brain biorepository management and operations

ATP13A2 variability in Parkinson disease.

Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease

Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities

Alpha synuclein protein levels are increased in serum from recently abstinent cocaine abusers

Alpha-synuclein aggregation and its relation to neurodegenerative diseases

Altered Dopamine Synaptic Markers in Postmortem Brain of Obese Subjects.

Alzheimer disease (AD) specific transcription, DNA methylation and splicing in twenty AD associated loci

An evaluation of the impact of MAPT, SNCA and APOE on the burden of Alzheimer's and Lewy body pathology

Assessment of stress markers in restrained individuals following physical stress with and without sham CED activation

Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Beyond Guam: the cyanobacteria/BMAA hypothesis of the cause of ALS and other neurodegenerative diseases

BisQC: an operational pipeline for multiplexed bisulfite sequencing

Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics.

Brain biomarkers for identifying excited delirium as a cause of sudden death

Breaking the cycle of opioid use disorder with Ibogaine

CNVs in neurodevelopmental disorders

CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit.

Cause, seasonality of death and co-morbidities in progressive supranuclear palsy (PSP).

Causes of death in multiple system atrophy

Cerebral uptake and protein incorporation of cyanobacterial toxin β-N-methylamino-L-alanine

Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum.

Clinical Heterogeneity of the LRRK2 G2019S Mutation

Cocaine abuse elevates alpha-synuclein and dopamine transporter levels in the human striatum

Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons.

Cocaine promotes primary human astrocyte proliferation via JNK-dependent up-regulation of cyclin A2.

Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates

Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster

Commentary on: Johnson MM, David JA, Michelhaugh SK, Schmidt CJ, Bannon MJ. Increased heat shock protein 70 gene expression in the brains of cocaine-related fatalities may be reflective of postdrug survival and intervention rather than excited delir

Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Correction: Somatic mtDNA Mutation Spectra in the Aging Human Putamen.

Correlating human and animal studies of cocaine abuse and gene expression.

Corrigendum to "Determinants of denervation-independent depletion of putamen dopamine in Parkinson's disease and multiple system atrophy" [Parkinsonism Relat. Disord. 35 (2017) 88-91]

Cortical and amygdalar Lewy body burden in Parkinson's disease patients with visual hallucinations

Criteria for the interpretation of cocaine levels in human biological samples and their relation to the cause of death

Cyanobacterial Neurotoxin BMAA and Mercury in Sharks

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-l-alanine (BMAA), in South Florida aquatic food webs ⬇️

Cyanobacterial neurotoxin BMAA and brain pathology in stranded dolphins

Cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) in shark fins

DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects

Decreased expression of the transcription factor NURR1 in dopamine neurons of cocaine abusers

Decreased vesicular storage and aldehyde dehydrogenase activity in multiple system atrophy

Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration.

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

Determinants of denervation-independent depletion of putamen dopamine in Parkinson's disease and multiple system atrophy.

Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain

Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay

Disparities in death certificates of Parkinson's disease patients: a report from a population of brain donors

Do vervets and macaques respond differently to BMAA?

Does cigarette smoking provide clinically significant neuroprotection among patients diagnosed with Parkinson's disease?

Dopamine transport function is elevated in cocaine users

Dopaminergic innervation of the human striatum in Parkinson's disease

Dynamics of hippocampal neurogenesis in adult humans

EXCITATION study: Unexplained in-custody deaths: Evaluating biomarkers of stress and agitation

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Environmental neurotoxins β-N-methylamino-l-alanine (BMAA) and mercury in shark cartilage dietary supplements

Excited Delirium Syndrome (ExDS): Defining Based on a Review of the Literature ⬇️

Excited Delirium and Sudden Death: A Syndromal Disorder at the Extreme End of the Neuropsychiatric Continuum

Expression of alpha-synuclein mRNA in Parkinson's disease

FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression

Family history of dementia: dementia with lewy bodies and dementia in Parkinson's disease

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models

GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats

GCH1 expression in human cerebellum from healthy individuals is not gender dependent

Galanin receptor over-expression within the amygdala in early Alzheimer's disease: an in vitro autoradiographic analysis

Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder

Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic variation in human NPY expression affects stress response and emotion

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease

Glucocerebrosidase mutations in diffuse Lewy body disease

Glucosidase-beta variations and Lewy body disorders

Hallucinations in multiple system atrophy