Lista de obras - Alessia Finotti - Dominio Público Uruguay

A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery

artículo científico publicado en 2020

A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia

article

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

scientific article published on 05 April 2020

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells

artículo científico publicado en 2017

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs

artículo científico publicado en 2022

A validated cellular biobank for β-thalassemia

artículo científico publicado en 2016

Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport

artículo científico publicado en 2019

An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production

artículo científico publicado en 2017

An antisense peptide nucleic acid against Pseudomonas aeruginosa inhibiting bacterial-induced inflammatory responses in the cystic fibrosis IB3-1 cellular model system.

artículo científico publicado en 2017

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression

artículo científico publicado en 2017

Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA.

artículo científico publicado en 2004

Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports.

artículo científico publicado en 2018

Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae

artículo científico publicado en 2016

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line

artículo científico publicado en 2017

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

artículo científico publicado en 2015

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters

artículo científico publicado en 2019

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

artículo científico publicado en 2009

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

artículo científico publicado en 2017

Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene

artículo científico publicado en 2012

Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients

artículo científico publicado en 2006

Efficient CRISPR-Cas9-based genome editing of β-globin gene on erythroid cells from homozygous β<sup>0</sup>39-thalassemia patients

artículo científico publicado en 2021

Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene

scientific article published on 28 February 2019

Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p

scientific article published on 01 June 2019

Epigenetic changes as a common trigger of muscle weakness in congenital myopathies

artículo científico publicado en 2015

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

artículo científico

Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses.

artículo científico publicado en 2014

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

artículo científico publicado en 2015

High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.

artículo científico publicado en 2015

Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs

artículo científico publicado en 2009

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

artículo científico publicado en 2015

Involvement of miRNA in erythroid differentiation

artículo científico

In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells

artículo científico publicado en 2011

Isothermal circular-strand-displacement polymerization of DNA and microRNA in digital microfluidic devices

artículo científico publicado en 2015

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review)

artículo científico publicado en 2018

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA).

artículo científico publicado en 2018

Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.

artículo científico publicado en 2011

MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells

artículo científico publicado en 2016

MicroRNAs and Long Non-coding RNAs in Genetic Diseases

artículo científico publicado en 2019

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

artículo científico publicado en 2011

Molecular methods for validation of the biological activity of peptide nucleic acids targeting microRNAs

artículo científico publicado en 2014

Multiple levels of control of the expression of the human A beta H-J-J locus encoding aspartyl-beta-hydroxylase, junctin, and junctate

artículo científico publicado en 2006

Myocyte enhancer factor 2 activates promoter sequences of the human AbetaH-J-J locus, encoding aspartyl-beta-hydroxylase, junctin, and junctate

artículo científico publicado en 2005

New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes.

artículo científico publicado en 2016

Non-invasive Prenatal Testing Using Fetal DNA

artículo científico publicado en 2019

Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future Expectations

PCR detection of segmented filamentous bacteria in the terminal ileum of patients with ulcerative colitis.

artículo científico publicado en 2017

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

artículo científico publicado en 2012

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

artículo científico publicado en 2014

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

artículo científico publicado en 2009

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

artículo científico publicado en 2013

Real-time multiplex analysis of four beta-thalassemia mutations employing surface plasmon resonance and biosensor technology

artículo científico publicado en 2004

Recent patents and technology transfer for molecular diagnosis of β-thalassemia and other hemoglobinopathies

artículo científico

Recent trends for novel options in experimental biological therapy of β-thalassemia

artículo científico publicado en 2014

Recent trends in the gene therapy of β-thalassemia

artículo científico publicado en 2015

Regulation of IL-8 gene expression in gliomas by microRNA miR-93.

artículo científico publicado en 2015

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

artículo científico publicado en 2012

Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels.

artículo científico publicado en 2016

Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor

artículo científico publicado en 2008

Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia

scientific article published on 12 July 2019

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

artículo científico publicado en 2020

Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma

artículo científico publicado en 2018

Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells.

artículo científico publicado en 2019

Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development

artículo científico

Tobramycin is a suppressor of premature termination codons

artículo científico publicado en 2013

Transcriptional activity and Sp 1/3 transcription factor binding to the P1 promoter sequences of the human AbetaH-J-J locus

artículo científico

Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis.

artículo científico publicado en 2016

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.

artículo científico publicado en 2010

UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation.

artículo científico publicado en 2018

Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus

artículo científico publicado en 2008

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.

artículo científico publicado en 2014

Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance

artículo científico publicado en 2016

miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

artículo científico publicado en 2016

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs

artículo científico

Lista de obras de Alessia Finotti

A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery

A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs

A validated cellular biobank for β-thalassemia

Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport

An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production

An antisense peptide nucleic acid against Pseudomonas aeruginosa inhibiting bacterial-induced inflammatory responses in the cystic fibrosis IB3-1 cellular model system.

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression

Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA.

Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports.

Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene

Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients

Efficient CRISPR-Cas9-based genome editing of β-globin gene on erythroid cells from homozygous β<sup>0</sup>39-thalassemia patients

Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene

Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p

Epigenetic changes as a common trigger of muscle weakness in congenital myopathies

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses.

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.

Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

Involvement of miRNA in erythroid differentiation

In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells

Isothermal circular-strand-displacement polymerization of DNA and microRNA in digital microfluidic devices

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review)

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA).

Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.

MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells

MicroRNAs and Long Non-coding RNAs in Genetic Diseases

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

Molecular methods for validation of the biological activity of peptide nucleic acids targeting microRNAs

Multiple levels of control of the expression of the human A beta H-J-J locus encoding aspartyl-beta-hydroxylase, junctin, and junctate

Myocyte enhancer factor 2 activates promoter sequences of the human AbetaH-J-J locus, encoding aspartyl-beta-hydroxylase, junctin, and junctate

New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes.

Non-invasive Prenatal Testing Using Fetal DNA

Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future Expectations

PCR detection of segmented filamentous bacteria in the terminal ileum of patients with ulcerative colitis.

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

Real-time multiplex analysis of four beta-thalassemia mutations employing surface plasmon resonance and biosensor technology

Recent patents and technology transfer for molecular diagnosis of β-thalassemia and other hemoglobinopathies

Recent trends for novel options in experimental biological therapy of β-thalassemia

Recent trends in the gene therapy of β-thalassemia

Regulation of IL-8 gene expression in gliomas by microRNA miR-93.

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels.

Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor

Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma

Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells.

Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development

Tobramycin is a suppressor of premature termination codons

Transcriptional activity and Sp 1/3 transcription factor binding to the P1 promoter sequences of the human AbetaH-J-J locus

Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis.

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.

UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation.

Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.

Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance

miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs