Lista de obras - Michele Simbolo - Dominio Público Uruguay

A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics

artículo científico publicado en 2015

Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations.

artículo científico publicado en 2016

BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing

artículo científico publicado en 2016

Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer

artículo científico publicado en 2017

Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers

artículo científico publicado en 2018

Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.

artículo científico publicado en 2015

Collapse of the Plasmacytoid Dendritic Cell Compartment in Advanced Cutaneous Melanomas by Components of the Tumor Cell Secretome

Collapse of the Plasmacytoid Dendritic Cells compartment in advanced cutaneous melanomas by components of the tumor cell secretome

Comparative Lesions Analysis Through a Targeted Sequencing Approach

artículo científico publicado en 2019

Comparison Between Prognostic Classifications in De Novo Metastatic Hormone Sensitive Prostate Cancer

artículo científico publicado en 2018

Complete remission with sunitinib in a poor-risk patient with metastatic renal cell carcinoma: the fine balance between toxicity and efficacy.

artículo científico publicado en 2015

Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis

artículo científico publicado en 2016

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours

artículo científico publicado en 2017

DNA qualification workflow for next generation sequencing of histopathological samples

artículo científico publicado en 2013

Diffuse gliomas in patients aged 55 years or over: A suggestion for IDH mutation testing

artículo científico publicado en 2019

ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance

artículo científico publicado en 2018

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

artículo científico publicado en 2013

Exosomal miRNA signatures of pancreatic lesions

scientific article published on 06 May 2020

Exploring the molecular and biological background of lung neuroendocrine tumours

scientific article published on 01 May 2019

Frequent NRG1 fusions in Caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression.

artículo científico publicado en 2018

Gene Expression Profiling of Lung Atypical Carcinoids and Large Cell Neuroendocrine Carcinomas Identifies Three Transcriptomic Subtypes with Specific Genomic Alterations

scientific article published on 11 May 2019

Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma.

artículo científico publicado en 2018

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations.

artículo científico publicado en 2018

Glioblastoma with tumor-to-tumor metastasis from lung adenocarcinoma

artículo científico publicado en 2019

High-throughput mutation profiling identifies novel molecular dysregulation in high-grade intraepithelial neoplasia and early gastric cancers.

artículo científico publicado en 2013

High-throughput mutation profiling improves diagnostic stratification of sporadic medullary thyroid carcinomas.

artículo científico publicado en 2014

Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease

artículo científico publicado en 2019

Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma

artículo científico publicado en 2022

Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities

artículo científico publicado en 2021

Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.

artículo científico publicado en 2016

MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma

artículo científico publicado en 2017

Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC

scientific article published on 24 August 2018

Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas

artículo científico publicado en 2018

Most high-grade neuroendocrine tumours of the lung are likely to secondarily develop from pre-existing carcinoids: innovative findings skipping the current pathogenesis paradigm

artículo científico publicado en 2018

Multigene mutational profiling of biliary tract cancer is related to the pattern of recurrence in surgically resected patients

artículo científico publicado en 2020

Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups

artículo científico publicado en 2014

Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine

artículo científico publicado en 2018

New genomic landscapes and therapeutic targets for biliary tract cancers

artículo científico

Next-Generation Histopathologic Diagnosis: A Lesson From a Hepatic Carcinosarcoma

Next-generation sequencing for genetic testing of familial colorectal cancer syndromes

artículo científico publicado en 2015

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

scientific article published on 21 February 2017

Patterns of gene mutations in bile duct cancers: is it time to overcome the anatomical classification?

artículo científico publicado en 2019

Pembrolizumab Activity in Recurrent High-Grade Gliomas with Partial or Complete Loss of Mismatch Repair Protein Expression: A Monocentric, Observational and Prospective Pilot Study

artículo científico publicado en 2020

Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis

artículo científico publicado en 2019

Reporting tumor molecular heterogeneity in histopathological diagnosis

artículo científico publicado en 2014

Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model

scientific article published on 27 January 2020

Ultra-Mutation in IDH Wild-Type Glioblastomas of Patients Younger than 55 Years is Associated with Defective Mismatch Repair, Microsatellite Instability, and Giant Cell Enrichment

scientific article published on 30 August 2019

Unmasking the impact of Rictor in cancer: novel insights of mTORC2 complex

artículo científico publicado en 2018

Whole-genome landscape of pancreatic neuroendocrine tumours.

artículo científico publicado en 2017

Lista de obras de Michele Simbolo

A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics

Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations.

BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing

Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer

Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers

Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.

Collapse of the Plasmacytoid Dendritic Cell Compartment in Advanced Cutaneous Melanomas by Components of the Tumor Cell Secretome

Collapse of the Plasmacytoid Dendritic Cells compartment in advanced cutaneous melanomas by components of the tumor cell secretome

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Comparison Between Prognostic Classifications in De Novo Metastatic Hormone Sensitive Prostate Cancer

Complete remission with sunitinib in a poor-risk patient with metastatic renal cell carcinoma: the fine balance between toxicity and efficacy.

Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours

DNA qualification workflow for next generation sequencing of histopathological samples

Diffuse gliomas in patients aged 55 years or over: A suggestion for IDH mutation testing

ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

Exosomal miRNA signatures of pancreatic lesions

Exploring the molecular and biological background of lung neuroendocrine tumours

Frequent NRG1 fusions in Caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression.

Gene Expression Profiling of Lung Atypical Carcinoids and Large Cell Neuroendocrine Carcinomas Identifies Three Transcriptomic Subtypes with Specific Genomic Alterations

Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma.

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations.

Glioblastoma with tumor-to-tumor metastasis from lung adenocarcinoma

High-throughput mutation profiling identifies novel molecular dysregulation in high-grade intraepithelial neoplasia and early gastric cancers.

High-throughput mutation profiling improves diagnostic stratification of sporadic medullary thyroid carcinomas.

Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease

Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma

Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities

Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.

MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma

Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC

Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas

Most high-grade neuroendocrine tumours of the lung are likely to secondarily develop from pre-existing carcinoids: innovative findings skipping the current pathogenesis paradigm

Multigene mutational profiling of biliary tract cancer is related to the pattern of recurrence in surgically resected patients

Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups

Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine

New genomic landscapes and therapeutic targets for biliary tract cancers

Next-Generation Histopathologic Diagnosis: A Lesson From a Hepatic Carcinosarcoma

Next-generation sequencing for genetic testing of familial colorectal cancer syndromes

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

Patterns of gene mutations in bile duct cancers: is it time to overcome the anatomical classification?

Pembrolizumab Activity in Recurrent High-Grade Gliomas with Partial or Complete Loss of Mismatch Repair Protein Expression: A Monocentric, Observational and Prospective Pilot Study

Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis

Reporting tumor molecular heterogeneity in histopathological diagnosis

Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model

Ultra-Mutation in IDH Wild-Type Glioblastomas of Patients Younger than 55 Years is Associated with Defective Mismatch Repair, Microsatellite Instability, and Giant Cell Enrichment

Unmasking the impact of Rictor in cancer: novel insights of mTORC2 complex

Whole-genome landscape of pancreatic neuroendocrine tumours.