Lista de obras - Leonard Girnita - Dominio Público Uruguay

Aberrant intracellular IGF-1R beta-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation.

artículo científico publicado en 2009

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.

artículo científico publicado en 2018

Decrypting noncoding RNA interactions, structures, and functional networks

scientific article published on 21 August 2019

Expression of insulin-like growth factor-1 receptor (IGF-1R) and p27Kip1 in melanocytic tumors: a potential regulatory role of IGF-1 pathway in distribution of p27Kip1 between different cyclins

artículo científico publicado en 2000

Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes.

artículo científico publicado en 2017

Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene ⬇️

artículo científico publicado el 23 de octubre de 2003

Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis

artículo científico publicado en 2017

IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.

artículo científico publicado en 2005

Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis

artículo científico publicado en 2008

Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model.

artículo científico publicado en 2005

Inhibition of G protein-coupled receptor kinase 2 promotes unbiased downregulation of IGF-1 receptor and restrains malignant cell growth

artículo científico publicado en 2020

Inhibition of N-linked glycosylation down-regulates insulin-like growth factor-1 receptor at the cell surface and kills Ewing's sarcoma cells: therapeutic implications

artículo científico publicado en 2000

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor

artículo científico publicado en 2008

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor

artículo científico publicado en 2008

Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma.

artículo científico publicado en 2005

Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs.

artículo científico publicado en 2012

Malignant solitary fibrous tumour of the orbit.

artículo científico publicado en 2008

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

artículo científico publicado en 2011

New picropodophyllin analogs via palladium-catalyzed allylic alkylation-Hiyama cross-coupling sequences.

artículo científico publicado en 2008

Non-Coding RNAs in IGF-1R Signaling Regulation: The Underlying Pathophysiological Link between Diabetes and Cancer

artículo científico publicado en 2019

Non-coding RNAs: the cancer genome dark matter that matters!

artículo científico publicado en 2016

Prediction of BAP1 Expression in Uveal Melanoma Using Densely-Connected Deep Classification Networks

artículo científico publicado en 2019

Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: intercorrelation and prognostic implications

scientific article published on 01 December 2005

Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression.

artículo científico publicado en 2014

Role of ubiquitination in IGF-1 receptor signaling and degradation

artículo científico publicado en 2007

Ruthenium-106 versus iodine-125 plaque brachytherapy of 571 choroidal melanomas with a thickness of ≥5.5 mm

artículo científico publicado en 2019

Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

artículo científico publicado en 2012

The coexistence of atypical intraductal hyperplasias with breast carcinoma

artículo científico publicado en 1998

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling

scientific article published on 01 July 2007

The tale of a tail: The secret behind IGF-1R's oncogenic power

scientific article published on 26 May 2020

Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.

artículo científico publicado en 2017

c-Kit-dependent growth of uveal melanoma cells: a potential therapeutic target?

artículo científico publicado en 2004

Lista de obras de Leonard Girnita

Aberrant intracellular IGF-1R beta-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation.

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.

Decrypting noncoding RNA interactions, structures, and functional networks

Expression of insulin-like growth factor-1 receptor (IGF-1R) and p27Kip1 in melanocytic tumors: a potential regulatory role of IGF-1 pathway in distribution of p27Kip1 between different cyclins

Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes.

Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene ⬇️

Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis

IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.

Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis

Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model.

Inhibition of G protein-coupled receptor kinase 2 promotes unbiased downregulation of IGF-1 receptor and restrains malignant cell growth

Inhibition of N-linked glycosylation down-regulates insulin-like growth factor-1 receptor at the cell surface and kills Ewing's sarcoma cells: therapeutic implications

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor

Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma.

Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs.

Malignant solitary fibrous tumour of the orbit.

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

New picropodophyllin analogs via palladium-catalyzed allylic alkylation-Hiyama cross-coupling sequences.

Non-Coding RNAs in IGF-1R Signaling Regulation: The Underlying Pathophysiological Link between Diabetes and Cancer

Non-coding RNAs: the cancer genome dark matter that matters!

Prediction of BAP1 Expression in Uveal Melanoma Using Densely-Connected Deep Classification Networks

Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: intercorrelation and prognostic implications

Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression.

Role of ubiquitination in IGF-1 receptor signaling and degradation

Ruthenium-106 versus iodine-125 plaque brachytherapy of 571 choroidal melanomas with a thickness of ≥5.5 mm

Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

The coexistence of atypical intraductal hyperplasias with breast carcinoma

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling

The tale of a tail: The secret behind IGF-1R's oncogenic power

Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.

c-Kit-dependent growth of uveal melanoma cells: a potential therapeutic target?