Lista de obras - Paolo Tortora - Dominio Público Uruguay

1H-NMR and photo-CIDNP spectroscopies show a possible role for Trp23 and Phe31 in nucleic acid binding by P2 ribonuclease from the archaeon Sulfolobus solfataricus

artículo científico publicado en 1995

A High Sensitivity Biosensor to detect the presence of perfluorinated compounds in environment.

artículo científico publicado en 2017

A Major Role for Side-Chain Polyglutamine Hydrogen Bonding in Irreversible Ataxin-3 Aggregation ⬇️

artículo científico publicado el 13 de abril de 2011

A conserved loop in polynucleotide phosphorylase (PNPase) essential for both RNA and ADP/phosphate binding

artículo científico publicado en 2013

A hydrophobic gold surface triggers misfolding and aggregation of the amyloidogenic Josephin domain in monomeric form, while leaving the oligomers unaffected

artículo científico publicado en 2013

A mutation in polynucleotide phosphorylase from Escherichia coli impairing RNA binding and degradosome stability

artículo científico publicado en 2004

A single-point mutation in the extreme heat- and pressure-resistant sso7d protein from sulfolobus solfataricus leads to a major rearrangement of the hydrophobic core

artículo científico publicado en 1999

Analysis of the Escherichia coli RNA degradosome composition by a proteomic approach

artículo científico publicado en 2005

Ataxin-3 is subject to autolytic cleavage.

artículo científico publicado en 2006

Avidin decorated core-shell nanoparticles for biorecognition studies by elastic light scattering.

artículo científico publicado en 2007

Biotechnological approaches toward nanoparticle biofunctionalization

artículo científico publicado en 2013

Dependence of mitochondrial protein synthesis initiation on formylation of the initiator methionyl-tRNAf.

artículo científico publicado en 1977

Dependence on cyclic AMP of glucose-induced inactivation of yeast gluconeogenetic enzymes

artículo científico publicado en 1983

Destabilization of non-pathological variants of ataxin-3 by metal ions results in aggregation/fibrillogenesis

artículo científico publicado en 2007

Different ataxin-3 amyloid aggregates induce intracellular Ca(2+) deregulation by different mechanisms in cerebellar granule cells

artículo científico publicado en 2013

Differential scanning calorimetry study of the thermodynamic stability of some mutants of Sso7d from Sulfolobus solfataricus.

artículo científico publicado en 1998

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

artículo científico publicado en 1991

Effect of caffeine on glucose-induced inactivation of gluconeogenetic enzymes in Saccharomyces cerevisiae. A possible role of cyclic AMP

artículo científico publicado en 1982

Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model

artículo científico publicado en 2017

Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model.

artículo científico publicado en 2014

Expression of a synthetic gene encoding P2 ribonuclease from the extreme thermoacidophilic archaebacterium Sulfolobus solfataricus in mesophylic hosts

artículo científico publicado en 1995

Extreme heat- and pressure-resistant 7-kDa protein P2 from the archaeon Sulfolobus solfataricus is dramatically destabilized by a single-point amino acid substitution ⬇️

artículo científico publicado el 1 de noviembre de 1997

Fourteen novel mucopolysaccharidosis IVA producing mutations in GALNS gene

scientific article published on 01 January 1997

Genetic analysis of polynucleotide phosphorylase structure and functions

article

Glucose-6-phosphate dehydrogenase deficiency in Italian blood donors: prevalence and molecular defect characterization.

artículo científico publicado en 2013

Glucose-dependent metabolic interconversion of fructose-1, 6-bisphosphatase in yeast

scientific article published on 01 May 1981

Glucose-induced degradation of yeast fructose-1,6-bisphosphatase requires additional triggering events besides protein phosphorylation

artículo científico publicado en 1987

Guanidine-induced unfolding of the Sso7d protein from the hyperthermophilic archaeon Sulfolobus solfataricus.

artículo científico publicado en 2004

Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells.

artículo científico publicado en 2011

How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode

artículo científico publicado en 2015

Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain

artículo científico publicado en 2013

Identification of a phosphorylated form of phosphoenolpyruvate carboxykinase from the yeast Saccharomyces cerevisiae

scientific article published on 01 September 1987

Immobilization of carboxypeptidase from Sulfolobus solfataricus on magnetic nanoparticles improves enzyme stability and functionality in organic media

artículo científico publicado en 2014

Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species

artículo científico publicado en 2017

Interaction of selected divalent metal ions with human ataxin-3 Q36.

artículo científico publicado en 2009

Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome

artículo científico publicado en 2014

Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles

artículo científico publicado en 2010

Metabolic effects of benzoate and sorbate in the yeast Saccharomyces cerevisiae at neutral pH

scientific article published on 01 January 1993

Molecular cloning, nucleotide sequence and expression of a Sulfolobus solfataricus gene encoding a class II fumarase.

artículo científico publicado en 1994

Multiple Presentation of Scfv800E6 on Silica Nanospheres Enhances Targeting Efficiency Toward HER-2 Receptor in Breast Cancer Cells ⬇️

artículo científico publicado el 31 de octubre de 2011

Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations.

scientific article published on 31 March 2017

Occurrence of two phosphorylated forms of yeast fructose-1,6-bisphosphatase with different isoelectric points

artículo científico publicado en 1988

Orientation-controlled conjugation of haloalkane dehalogenase fused homing peptides to multifunctional nanoparticles for the specific recognition of cancer cells.

artículo científico publicado en 2013

Peptide-nanoparticle ligation mediated by cutinase fusion for the development of cancer cell-targeted nanoconjugates

artículo científico publicado en 2015

Photometric Assay for Polynucleotide Phosphorylase

artículo científico publicado en 1999

Polynucleotide phosphorylase-based photometric assay for inorganic phosphate

artículo científico publicado en 2004

Properties of recombinant human cytosolic sialidase HsNEU2. The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules

artículo científico publicado en 2003

Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol

artículo científico publicado en 2018

Protein nanocages for self-triggered nuclear delivery of DNA-targeted chemotherapeutics in Cancer Cells

artículo científico publicado en 2014

Purification and characterization of a thermostable carboxypeptidase from the extreme thermophilic archaebacterium Sulfolobus solfataricus

artículo científico publicado el 1 de junio de 1992

Purification of phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae and its use for bicarbonate assay

scientific article published on 01 January 1985

Reactivation of yeast glucose-6-phosphate dehydrogenase denaturated by saturated fatty acids.

artículo científico publicado en 1982

Regulation of Escherichia coli polynucleotide phosphorylase by ATP.

artículo científico publicado en 2008

Regulation of maltose utilization in Saccharomyces cerevisiae by genes of the RAS/protein kinase A pathway

scientific article published on 01 February 1997

Ribonucleases from the extreme thermophilic archaebacterium S. solfataricus.

artículo científico publicado en 1993

Selective denaturation of several yeast enzymes by free fatty acids ⬇️

artículo científico publicado el 7 de agosto de 1978

Single-domain protein A-engineered magnetic nanoparticles: toward a universal strategy to site-specific labeling of antibodies for targeted detection of tumor cells

artículo científico publicado en 2010

Site-Specific Mutation of Staphylococcus aureus VraS Reveals a Crucial Role for the VraR-VraS Sensor in the Emergence of Glycopeptide Resistance ⬇️

artículo científico publicado el 20 de diciembre de 2010

Site-specific conjugation of ScFvs antibodies to nanoparticles by bioorthogonal strain-promoted alkyne-nitrone cycloaddition

artículo científico publicado en 2011

Structural features responsible for kinetic thermal stability of a carboxypeptidase from the archaebacterium Sulfolobus solfataricus.

artículo científico publicado en 1993

Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis.

artículo científico publicado en 2009

Studies on glucose-induced inactivation of gluconeogenetic enzymes in adenylate cyclase and cAMP-dependent protein kinase yeast mutants

artículo científico publicado en 1984

Studies on the degradative mechanism of phosphoenolpyruvate carboxykinase from yeast Saccharomyces cerevisiae

artículo científico publicado en 1989

Susceptibility to proteinases of yeast enzymes selectively modified by fatty acids

artículo científico publicado en 1982

Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

scholarly article by Sofia Giorgetti published in September 2018

Temperature profoundly affects ataxin-3 fibrillogenesis ⬇️

artículo científico publicado el 9 de enero de 2012

Temperature-dependent, irreversible formation of amyloid fibrils by a soluble human ataxin-3 carrying a moderately expanded polyglutamine stretch (Q36).

artículo científico publicado en 2003

The KH and S1 domains of Escherichia coli polynucleotide phosphorylase are necessary for autoregulation and growth at low temperature

artículo científico publicado en 2007

The Sso7d DNA-binding protein from Sulfolobus solfataricus has ribonuclease activity

artículo científico publicado en 2001

The Toxic Effects of Pathogenic Ataxin-3 Variants in a Yeast Cellular Model

artículo científico publicado en 2015

The conformational ensemble of the disordered and aggregation-protective 182-291 region of ataxin-3.

artículo científico publicado en 2013

The mechanism of the polynucleotide phosphorylase-catalyzed arsenolysis of ADP.

artículo científico publicado en 2010

The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris

artículo científico publicado en 2017

The powerful high pressure tool for protein conformational studies

artículo científico publicado en 2005

The relationship between aggregation and toxicity of polyglutamine-containing ataxin-3 in the intracellular environment of Escherichia coli

artículo científico publicado en 2012

The role of phenylalanine 31 in maintaining the conformational stability of ribonuclease P2 from Sulfolobus solfataricus under extreme conditions of temperature and pressure.

artículo científico publicado en 1997

The role of the central flexible region on the aggregation and conformational properties of human ataxin-3

artículo científico publicado en 2012

Thermal stability and DNA binding activity of a variant form of the Sso7d protein from the archeon Sulfolobus solfataricus truncated at leucine 54.

artículo científico publicado en 2003

Transcriptional and post-transcriptional control of polynucleotide phosphorylase during cold acclimation in Escherichia coli

artículo científico publicado en 2000

Uniform lipopolysaccharide (LPS)-loaded magnetic nanoparticles for the investigation of LPS-TLR4 signaling.

artículo científico publicado en 2010

Various Cells Retrovirally Transduced withN-Acetylgalactosoamine-6-Sulfate Sulfatase Correct Morquio Skin FibroblastsIn Vitro ⬇️

artículo científico publicado el 1 de noviembre de 2001

Lista de obras de Paolo Tortora

1H-NMR and photo-CIDNP spectroscopies show a possible role for Trp23 and Phe31 in nucleic acid binding by P2 ribonuclease from the archaeon Sulfolobus solfataricus

A High Sensitivity Biosensor to detect the presence of perfluorinated compounds in environment.

A Major Role for Side-Chain Polyglutamine Hydrogen Bonding in Irreversible Ataxin-3 Aggregation ⬇️

A conserved loop in polynucleotide phosphorylase (PNPase) essential for both RNA and ADP/phosphate binding

A hydrophobic gold surface triggers misfolding and aggregation of the amyloidogenic Josephin domain in monomeric form, while leaving the oligomers unaffected

A mutation in polynucleotide phosphorylase from Escherichia coli impairing RNA binding and degradosome stability

A single-point mutation in the extreme heat- and pressure-resistant sso7d protein from sulfolobus solfataricus leads to a major rearrangement of the hydrophobic core

Analysis of the Escherichia coli RNA degradosome composition by a proteomic approach

Ataxin-3 is subject to autolytic cleavage.

Avidin decorated core-shell nanoparticles for biorecognition studies by elastic light scattering.

Biotechnological approaches toward nanoparticle biofunctionalization

Dependence of mitochondrial protein synthesis initiation on formylation of the initiator methionyl-tRNAf.

Dependence on cyclic AMP of glucose-induced inactivation of yeast gluconeogenetic enzymes

Destabilization of non-pathological variants of ataxin-3 by metal ions results in aggregation/fibrillogenesis

Different ataxin-3 amyloid aggregates induce intracellular Ca(2+) deregulation by different mechanisms in cerebellar granule cells

Differential scanning calorimetry study of the thermodynamic stability of some mutants of Sso7d from Sulfolobus solfataricus.

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

Effect of caffeine on glucose-induced inactivation of gluconeogenetic enzymes in Saccharomyces cerevisiae. A possible role of cyclic AMP

Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model

Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model.

Expression of a synthetic gene encoding P2 ribonuclease from the extreme thermoacidophilic archaebacterium Sulfolobus solfataricus in mesophylic hosts

Extreme heat- and pressure-resistant 7-kDa protein P2 from the archaeon Sulfolobus solfataricus is dramatically destabilized by a single-point amino acid substitution ⬇️

Fourteen novel mucopolysaccharidosis IVA producing mutations in GALNS gene

Genetic analysis of polynucleotide phosphorylase structure and functions

Glucose-6-phosphate dehydrogenase deficiency in Italian blood donors: prevalence and molecular defect characterization.

Glucose-dependent metabolic interconversion of fructose-1, 6-bisphosphatase in yeast

Glucose-induced degradation of yeast fructose-1,6-bisphosphatase requires additional triggering events besides protein phosphorylation

Guanidine-induced unfolding of the Sso7d protein from the hyperthermophilic archaeon Sulfolobus solfataricus.

Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells.

How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode

Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain

Identification of a phosphorylated form of phosphoenolpyruvate carboxykinase from the yeast Saccharomyces cerevisiae

Immobilization of carboxypeptidase from Sulfolobus solfataricus on magnetic nanoparticles improves enzyme stability and functionality in organic media

Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species

Interaction of selected divalent metal ions with human ataxin-3 Q36.

Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome

Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles

Metabolic effects of benzoate and sorbate in the yeast Saccharomyces cerevisiae at neutral pH

Molecular cloning, nucleotide sequence and expression of a Sulfolobus solfataricus gene encoding a class II fumarase.

Multiple Presentation of Scfv800E6 on Silica Nanospheres Enhances Targeting Efficiency Toward HER-2 Receptor in Breast Cancer Cells ⬇️

Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations.

Occurrence of two phosphorylated forms of yeast fructose-1,6-bisphosphatase with different isoelectric points

Orientation-controlled conjugation of haloalkane dehalogenase fused homing peptides to multifunctional nanoparticles for the specific recognition of cancer cells.

Peptide-nanoparticle ligation mediated by cutinase fusion for the development of cancer cell-targeted nanoconjugates

Photometric Assay for Polynucleotide Phosphorylase

Polynucleotide phosphorylase-based photometric assay for inorganic phosphate

Properties of recombinant human cytosolic sialidase HsNEU2. The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules

Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol

Protein nanocages for self-triggered nuclear delivery of DNA-targeted chemotherapeutics in Cancer Cells

Purification and characterization of a thermostable carboxypeptidase from the extreme thermophilic archaebacterium Sulfolobus solfataricus

Purification of phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae and its use for bicarbonate assay

Reactivation of yeast glucose-6-phosphate dehydrogenase denaturated by saturated fatty acids.

Regulation of Escherichia coli polynucleotide phosphorylase by ATP.

Regulation of maltose utilization in Saccharomyces cerevisiae by genes of the RAS/protein kinase A pathway

Ribonucleases from the extreme thermophilic archaebacterium S. solfataricus.

Selective denaturation of several yeast enzymes by free fatty acids ⬇️

Single-domain protein A-engineered magnetic nanoparticles: toward a universal strategy to site-specific labeling of antibodies for targeted detection of tumor cells

Site-Specific Mutation of Staphylococcus aureus VraS Reveals a Crucial Role for the VraR-VraS Sensor in the Emergence of Glycopeptide Resistance ⬇️

Site-specific conjugation of ScFvs antibodies to nanoparticles by bioorthogonal strain-promoted alkyne-nitrone cycloaddition

Structural features responsible for kinetic thermal stability of a carboxypeptidase from the archaebacterium Sulfolobus solfataricus.

Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis.

Studies on glucose-induced inactivation of gluconeogenetic enzymes in adenylate cyclase and cAMP-dependent protein kinase yeast mutants

Studies on the degradative mechanism of phosphoenolpyruvate carboxykinase from yeast Saccharomyces cerevisiae

Susceptibility to proteinases of yeast enzymes selectively modified by fatty acids

Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

Temperature profoundly affects ataxin-3 fibrillogenesis ⬇️

Temperature-dependent, irreversible formation of amyloid fibrils by a soluble human ataxin-3 carrying a moderately expanded polyglutamine stretch (Q36).

The KH and S1 domains of Escherichia coli polynucleotide phosphorylase are necessary for autoregulation and growth at low temperature

The Sso7d DNA-binding protein from Sulfolobus solfataricus has ribonuclease activity

The Toxic Effects of Pathogenic Ataxin-3 Variants in a Yeast Cellular Model

The conformational ensemble of the disordered and aggregation-protective 182-291 region of ataxin-3.

The mechanism of the polynucleotide phosphorylase-catalyzed arsenolysis of ADP.

The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris

The powerful high pressure tool for protein conformational studies

The relationship between aggregation and toxicity of polyglutamine-containing ataxin-3 in the intracellular environment of Escherichia coli

The role of phenylalanine 31 in maintaining the conformational stability of ribonuclease P2 from Sulfolobus solfataricus under extreme conditions of temperature and pressure.

The role of the central flexible region on the aggregation and conformational properties of human ataxin-3

Thermal stability and DNA binding activity of a variant form of the Sso7d protein from the archeon Sulfolobus solfataricus truncated at leucine 54.

Transcriptional and post-transcriptional control of polynucleotide phosphorylase during cold acclimation in Escherichia coli