Lista de obras - Jérome Fagart - Dominio Público Uruguay

11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.

artículo científico publicado en 2002

A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach

artículo científico publicado en 2000

A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones

artículo científico publicado en 2000

A structural explanation of the effects of dissociated glucocorticoids on glucocorticoid receptor transactivation.

artículo científico publicado en 2013

ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure

artículo científico publicado en 2018

Agonists and antagonists of mineralocorticoids. The relation between structure and activity

artículo científico publicado en 2004

Antagonism in the human mineralocorticoid receptor.

artículo científico publicado en 1998

Antagonistic effects of finerenone and spironolactone on the aldosterone-regulated transcriptome of human kidney cells

artículo científico publicado en 2021

Characterization of seven novel mutations on the HEXB gene in French Sandhoff patients

artículo científico publicado en 2012

Cistrome of the aldosterone-activated mineralocorticoid receptor in human renal cells.

artículo científico publicado en 2015

Corticosteroid receptors adopt distinct cyclical transcriptional signatures

scientific article published on 07 May 2018

Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor

artículo científico publicado en 2000

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.

artículo científico publicado en 2005

Familial Multiplicity of Estrogen Insensitivity Associated With a Loss-of-Function ESR1 Mutation

artículo científico publicado en 2016

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1.

artículo científico publicado en 2015

Glucocorticoid metabolism by 11-beta hydroxysteroid dehydrogenase type 2 modulates human mineralocorticoid receptor transactivation activity.

artículo científico publicado en 2003

HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis

artículo científico publicado en 2017

Identification of Multiple Gene Mutations Accounts for a new Genetic Architecture of Primary Ovarian Insufficiency.

artículo científico publicado en 2016

Identification of Periplakin as a New Target for Autoreactivity in Idiopathic Pulmonary Fibrosis ⬇️

artículo científico publicado el 8 de octubre de 2010

Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure.

artículo científico publicado en 1996

Mechanistic aspects of mineralocorticoid receptor activation

artículo científico publicado en 2000

Mineralocorticoid receptor mutations are the principal cause of renal type 1 pseudohypoaldosteronism

artículo científico publicado en 2007

Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1.

artículo científico publicado en 2010

Molecular determinants of the recognition of ulipristal acetate by oxo-steroid receptors

artículo científico publicado en 2014

Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies.

artículo científico publicado en 2016

New steroidal diazo ketones as potential photoaffinity labeling reagents for the mineralocorticoid receptor: synthesis and biological activities.

artículo científico publicado en 1996

Photoaffinity labelling of the human mineralocorticoid receptor with steroids having a reactive group at position 3, 18 or 21.

artículo científico publicado en 1998

Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease.

artículo científico publicado en 1999

RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity.

artículo científico publicado en 2017

Structural determinants of ligand binding to the mineralocorticoid receptor.

artículo científico

Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor.

artículo científico publicado en 1996

The Met852 residue is a key organizer of the ligand-binding cavity of the human mineralocorticoid receptor.

artículo científico publicado en 2005

The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.

artículo científico publicado en 2003

The synthetic androgen methyltrienolone (r1881) acts as a potent antagonist of the mineralocorticoid receptor.

artículo científico publicado en 2006

Three Novel Heterozygous Point Mutations of NR3C1 Causing Glucocorticoid Resistance

artículo científico publicado en 2016

[Corticosteroid hormones: mechanisms involved in the recognition of aldosterone by mineralocorticoid receptors]

artículo científico publicado en 1999

Lista de obras de Jérome Fagart

11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.

A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach

A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones

A structural explanation of the effects of dissociated glucocorticoids on glucocorticoid receptor transactivation.

ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure

Agonists and antagonists of mineralocorticoids. The relation between structure and activity

Antagonism in the human mineralocorticoid receptor.

Antagonistic effects of finerenone and spironolactone on the aldosterone-regulated transcriptome of human kidney cells

Characterization of seven novel mutations on the HEXB gene in French Sandhoff patients

Cistrome of the aldosterone-activated mineralocorticoid receptor in human renal cells.

Corticosteroid receptors adopt distinct cyclical transcriptional signatures

Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.

Familial Multiplicity of Estrogen Insensitivity Associated With a Loss-of-Function ESR1 Mutation

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1.

Glucocorticoid metabolism by 11-beta hydroxysteroid dehydrogenase type 2 modulates human mineralocorticoid receptor transactivation activity.

HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis

Identification of Multiple Gene Mutations Accounts for a new Genetic Architecture of Primary Ovarian Insufficiency.

Identification of Periplakin as a New Target for Autoreactivity in Idiopathic Pulmonary Fibrosis ⬇️

Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure.

Mechanistic aspects of mineralocorticoid receptor activation

Mineralocorticoid receptor mutations are the principal cause of renal type 1 pseudohypoaldosteronism

Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1.

Molecular determinants of the recognition of ulipristal acetate by oxo-steroid receptors

Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies.

New steroidal diazo ketones as potential photoaffinity labeling reagents for the mineralocorticoid receptor: synthesis and biological activities.

Photoaffinity labelling of the human mineralocorticoid receptor with steroids having a reactive group at position 3, 18 or 21.

Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease.

RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity.

Structural determinants of ligand binding to the mineralocorticoid receptor.

Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor.

The Met852 residue is a key organizer of the ligand-binding cavity of the human mineralocorticoid receptor.

The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.

The synthetic androgen methyltrienolone (r1881) acts as a potent antagonist of the mineralocorticoid receptor.

Three Novel Heterozygous Point Mutations of NR3C1 Causing Glucocorticoid Resistance

[Corticosteroid hormones: mechanisms involved in the recognition of aldosterone by mineralocorticoid receptors]