Lista de obras - L Lafanechère - Dominio Público Uruguay

A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

artículo científico publicado en 2018

A revised nomenclature for the human and rodent alpha-tubulin gene family

artículo científico publicado en 2007

Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells.

artículo científico publicado en 2013

Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2

artículo científico publicado en 2010

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.

artículo científico publicado en 2013

BCIRG 001 molecular analysis: prognostic factors in node-positive breast cancer patients receiving adjuvant chemotherapy.

artículo científico publicado en 2010

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.

artículo científico publicado en 2009

Control-Plate Regression (CPR) Normalization for High-Throughput Screens with Many Active Features.

artículo científico publicado en 2013

Expanding the chemical diversity of CK2 inhibitors.

artículo científico publicado en 2008

Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy.

artículo científico publicado en 2005

High-content screening for the discovery of pharmacological compounds: advantages, challenges and potential benefits of recent technological developments.

artículo científico

Identification of proteins binding the native tubulin dimer

artículo científico publicado en 2005

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties

artículo científico publicado en 2017

Improving detection of rare biological events in high-throughput screens

artículo científico publicado en 2014

Intensity quantile estimation and mapping--a novel algorithm for the correction of image non-uniformity bias in HCS data.

artículo científico publicado en 2012

LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers

artículo científico publicado en 2016

LIM kinases: cofilin and beyond.

artículo científico publicado en 2017

LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.

artículo científico publicado en 2016

LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

scientific article published on 17 July 2019

Les années 2010

Miniaturization and validation of a sensitive multiparametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents

scientific article published on 28 April 2006

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights

artículo científico publicado en 2010

Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations

artículo científico publicado en 2014

Novel synthetic pharmacophores inducing a stabilization of cellular microtubules.

artículo científico publicado en 2015

Parthenolide inhibits tubulin carboxypeptidase activity

artículo científico publicado en 2007

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

artículo científico publicado en 2012

Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator

artículo científico publicado en 2013

Preliminary crystallographic study of a complex formed between the alpha/beta-tubulin heterodimer and the neuronal growth-associated protein SCG10

scientific article published on 01 August 2000

Preparation of pure tyrosinated or detyrosinated tubulin isoforms

artículo científico publicado en 2011

Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia

scientific article published on 12 March 2021

Salicylaldehyde derivatives as new protein kinase CK2 inhibitors.

artículo científico publicado en 2008

Separation of tubulin subunits under nondenaturing conditions.

artículo científico publicado en 1998

Single assay-wide variance experimental (SAVE) design for high-throughput screening

artículo científico publicado en 2013

Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches

article

Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.

artículo científico publicado en 2013

Suppression of nuclear oscillations in Saccharomyces cerevisiae expressing Glu tubulin.

scholarly article

Targeting LIM kinases in taxane resistant tumors

artículo científico publicado en 2016

The pyrrolopyrimidine colchicine-binding site agent PP-13 reduces the metastatic dissemination of invasive cancer cells in vitro and in vivo

scientific article published on 07 December 2018

The third tubulin pool.

artículo científico publicado en 2000

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

artículo científico publicado en 2006

Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells

artículo científico publicado en 2020

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation.

artículo científico publicado en 2017

[Chemical biology: cross-border strategies]

artículo científico publicado en 2014

[On the road to deciphering the tubulin code: focus on acetylation and detyrosination]

scientific article published on 01 December 2018

β3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner

artículo científico publicado en 2016

Lista de obras de L Lafanechère

A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

A revised nomenclature for the human and rodent alpha-tubulin gene family

Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells.

Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.

BCIRG 001 molecular analysis: prognostic factors in node-positive breast cancer patients receiving adjuvant chemotherapy.

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.

Control-Plate Regression (CPR) Normalization for High-Throughput Screens with Many Active Features.

Expanding the chemical diversity of CK2 inhibitors.

Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy.

High-content screening for the discovery of pharmacological compounds: advantages, challenges and potential benefits of recent technological developments.

Identification of proteins binding the native tubulin dimer

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties

Improving detection of rare biological events in high-throughput screens

Intensity quantile estimation and mapping--a novel algorithm for the correction of image non-uniformity bias in HCS data.

LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers

LIM kinases: cofilin and beyond.

LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.

LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

Les années 2010

Miniaturization and validation of a sensitive multiparametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights

Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations

Novel synthetic pharmacophores inducing a stabilization of cellular microtubules.

Parthenolide inhibits tubulin carboxypeptidase activity

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator

Preliminary crystallographic study of a complex formed between the alpha/beta-tubulin heterodimer and the neuronal growth-associated protein SCG10

Preparation of pure tyrosinated or detyrosinated tubulin isoforms

Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia

Salicylaldehyde derivatives as new protein kinase CK2 inhibitors.

Separation of tubulin subunits under nondenaturing conditions.

Single assay-wide variance experimental (SAVE) design for high-throughput screening

Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches

Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.

Suppression of nuclear oscillations in Saccharomyces cerevisiae expressing Glu tubulin.

Targeting LIM kinases in taxane resistant tumors

The pyrrolopyrimidine colchicine-binding site agent PP-13 reduces the metastatic dissemination of invasive cancer cells in vitro and in vivo

The third tubulin pool.

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation.

[Chemical biology: cross-border strategies]

[On the road to deciphering the tubulin code: focus on acetylation and detyrosination]

β3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner