Lista de obras - Daniel Christ - Dominio Público Uruguay

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

scientific article published on 01 April 2011

Aggregation, stability, and formulation of human antibody therapeutics

artículo científico

Bispecific antibodies with native chain structure.

artículo científico publicado en 2014

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

artículo científico publicado en 2019

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

artículo científico publicado en 2017

Challenges and opportunities for non-antibody scaffold drugs

artículo científico publicado en 2015

Circumventing the stability-function trade-off in an engineered FN3 domain

artículo científico publicado en 2016

Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

scientific article published on 26 September 2019

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization.

artículo científico publicado en 2016

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis

artículo científico publicado en 2014

Crystal structure of duck egg lysozyme isoform II (DEL-II)

artículo científico publicado en 2018

Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes.

artículo científico publicado en 2017

DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells

artículo científico publicado en 2020

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

scientific article published on 18 September 2019

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

artículo científico publicado en 2017

Efficient Intracellular Delivery of CRISPR-Cas Ribonucleoproteins through Receptor Mediated Endocytosis

artículo científico publicado en 2019

Engineering Escherichia coli heat-resistance by synthetic gene amplification

artículo científico publicado en 2008

Erratum: The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

article

Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells

scientific article published on 01 January 2019

Expression of IgG Monoclonals with Engineered Immune Effector Functions

artículo científico publicado en 2018

Expression of high-affinity human antibody fragments in bacteria.

artículo científico publicado en 2012

Expression, purification and characterization of recombinant interleukin-21.

artículo científico publicado en 2010

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production

artículo científico publicado en 2015

Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies

artículo científico publicado en 2015

GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS

scientific article published on 31 May 2019

General strategy for the generation of human antibody variable domains with increased aggregation resistance

artículo científico publicado en 2012

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.

artículo científico publicado en 2018

Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

artículo científico publicado en 2011

Human Antibody Bispecifics through Phage Display Selection

scientific article published on 22 March 2019

I-motif DNA structures are formed in the nuclei of human cells.

artículo científico publicado en 2018

IL-2 Shapes the Survival and Plasticity of IL-17-Producing γδ T Cells.

artículo científico publicado en 2017

IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.

artículo científico publicado en 2013

Identification of aggregation inhibitors of the human antibody light chain repertoire by phage display

artículo científico publicado en 2014

Identification of functional similarities between proteins using directed evolution

artículo científico publicado en 2003

Identification of protein domains by shotgun proteolysis

artículo científico publicado en 2006

Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models. ⬇️

artículo científico publicado en 2011

NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers

artículo científico publicado en 2021

Next-Generation Sequencing of Antibody Display Repertoires.

artículo científico publicado en 2018

Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells

artículo científico publicado en 2017

Rapid prediction of expression and refolding yields using phage display.

artículo científico publicado en 2013

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

artículo científico publicado en 2014

Repertoires of aggregation-resistant human antibody domains

artículo científico publicado en 2007

Selection of Antibody Fragments Against Structured DNA by Phage Display

artículo científico publicado en 2018

Selection of human antibody fragments by phage display

artículo científico publicado en 2007

Sequence determinants of protein aggregation in human VH domains

artículo científico publicado en 2008

Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood

artículo científico publicado en 2018

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis

artículo científico publicado en 2015

Stability engineering of the human antibody repertoire

artículo científico publicado en 2014

Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

artículo científico publicado en 2015

Structural basis of antigen recognition: crystal structure of duck egg lysozyme

artículo científico publicado en 2017

Structural reconstruction of protein ancestry

artículo científico publicado en 2017

Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.

artículo científico publicado en 2017

Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation

artículo científico publicado en 2021

Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation

Systematic functional identification of cancer multi-drug resistance genes

artículo científico publicado en 2020

Tapping diversity lost in transformations--in vitro amplification of ligation reactions

artículo científico publicado en 2006

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

scientific journal article

Thermodynamically stable aggregation-resistant antibody domains through directed evolution

artículo científico publicado en 2007

Transient expression of human antibodies in mammalian cells.

artículo científico publicado en 2017

Lista de obras de Daniel Christ

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

Aggregation, stability, and formulation of human antibody therapeutics

Bispecific antibodies with native chain structure.

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

Challenges and opportunities for non-antibody scaffold drugs

Circumventing the stability-function trade-off in an engineered FN3 domain

Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization.

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis

Crystal structure of duck egg lysozyme isoform II (DEL-II)

Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes.

DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

Efficient Intracellular Delivery of CRISPR-Cas Ribonucleoproteins through Receptor Mediated Endocytosis

Engineering Escherichia coli heat-resistance by synthetic gene amplification

Erratum: The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells

Expression of IgG Monoclonals with Engineered Immune Effector Functions

Expression of high-affinity human antibody fragments in bacteria.

Expression, purification and characterization of recombinant interleukin-21.

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production

Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies

GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS

General strategy for the generation of human antibody variable domains with increased aggregation resistance

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.

Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

Human Antibody Bispecifics through Phage Display Selection

I-motif DNA structures are formed in the nuclei of human cells.

IL-2 Shapes the Survival and Plasticity of IL-17-Producing γδ T Cells.

IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.

Identification of aggregation inhibitors of the human antibody light chain repertoire by phage display

Identification of functional similarities between proteins using directed evolution

Identification of protein domains by shotgun proteolysis

Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models. ⬇️

NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers

Next-Generation Sequencing of Antibody Display Repertoires.

Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells

Rapid prediction of expression and refolding yields using phage display.

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

Repertoires of aggregation-resistant human antibody domains

Selection of Antibody Fragments Against Structured DNA by Phage Display

Selection of human antibody fragments by phage display

Sequence determinants of protein aggregation in human VH domains

Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis

Stability engineering of the human antibody repertoire

Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

Structural basis of antigen recognition: crystal structure of duck egg lysozyme

Structural reconstruction of protein ancestry

Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.

Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation

Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation

Systematic functional identification of cancer multi-drug resistance genes

Tapping diversity lost in transformations--in vitro amplification of ligation reactions

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

Thermodynamically stable aggregation-resistant antibody domains through directed evolution

Transient expression of human antibodies in mammalian cells.