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Lista de obras de Stephen D. Thorpe

Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation

artículo científico publicado en 2015

An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation

scientific article published on 22 March 2019

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells

artículo científico publicado en 2015

Cell-matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure

artículo científico publicado en 2012

Chondrogenesis and integration of mesenchymal stem cells within an in vitro cartilage defect repair model

artículo científico publicado en 2009

Composition-function relations of cartilaginous tissues engineered from chondrocytes and mesenchymal stem cells isolated from bone marrow and infrapatellar fat pad

scientific article published on 29 December 2010

Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells

artículo científico publicado en 2012

Differential effects of LifeAct-GFP and actin-GFP on cell mechanics assessed using micropipette aspiration.

artículo científico publicado en 2015

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

artículo científico publicado en 2016

Dynamic regulation of nuclear architecture and mechanics-a rheostatic role for the nucleus in tailoring cellular mechanosensitivity.

artículo científico publicado en 2017

Engineering of large cartilaginous tissues through the use of microchanneled hydrogels and rotational culture

scientific article published on 01 November 2009

Engineering zonal cartilaginous tissue by modulating oxygen levels and mechanical cues through the depth of infrapatellar fat pad stem cell laden hydrogels.

artículo científico publicado en 2016

European Society of Biomechanics S.M. Perren Award 2012: the external mechanical environment can override the influence of local substrate in determining stem cell fate.

artículo científico publicado en 2012

Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells

scientific article published on 14 December 2009

GPER Activation Inhibits Cancer Cell Mechanotransduction and Basement Membrane Invasion via RhoA

scientific article published on 25 January 2020

GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment

scientific article published on 11 December 2018

Highlight on the dynamic organization of the nucleus

artículo científico publicado en 2016

Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression

artículo científico publicado en 2010

Modulating gradients in regulatory signals within mesenchymal stem cell seeded hydrogels: a novel strategy to engineer zonal articular cartilage.

artículo científico publicado en 2013

Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria.

artículo científico publicado en 2017

Retinoic Acid Receptor-β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin-Driven Activation and Durotaxis in Hepatic Stellate Cells

artículo científico publicado en 2018

Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2

scientific article published in 2023

Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria

artículo científico publicado en 2016

Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics.

artículo científico publicado en 2014

Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway

artículo científico publicado en 2020

Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor

artículo científico publicado en 2018

Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival

scientific article published on 11 December 2018

Temporal and spatial changes in cartilage-matrix-specific gene expression in mesenchymal stem cells in response to dynamic compression.

artículo científico publicado en 2011

The Effect of Gradations in Mineral Content, Matrix Alignment, and Applied Strain on Human Mesenchymal Stem Cell Morphology within Collagen Biomaterials.

artículo científico publicado en 2016

The Response of Bone Marrow-Derived Mesenchymal Stem Cells to Dynamic Compression Following TGF-β3 Induced Chondrogenic Differentiation

article

The application of plastic compression to modulate fibrin hydrogel mechanical properties

artículo científico publicado en 2012

The effect of concentration, thermal history and cell seeding density on the initial mechanical properties of agarose hydrogels

artículo científico publicado en 2008

The effects of dynamic compression on the development of cartilage grafts engineered using bone marrow and infrapatellar fat pad derived stem cells.

artículo científico publicado en 2015