Lista de obras - John F Marshall - Dominio Público Uruguay

A framework for the development of effective anti-metastatic agents

artículo científico publicado en 2019

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

artículo científico publicado en 2014

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

artículo científico publicado en 2013

Activation status and function of the VLA-4 (α4β1) integrin expressed on human melanoma cell lines ⬇️

artículo científico publicado el 9 de octubre de 1997

AlphaV integrins play an important role in myofibroblast differentiation

artículo científico publicado en 2004

Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis

artículo científico publicado en 2009

Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence

artículo científico

Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.

artículo científico publicado en 2010

Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer

artículo científico publicado en 2003

Correlative 3D Structured Illumination Microscopy and Single-Molecule Localization Microscopy for Imaging Cancer Invasion

artículo científico publicado en 2018

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

artículo científico publicado en 2013

Current Perspectives on the Use of off the Shelf CAR-T/NK Cells for the Treatment of Cancer

Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion.

artículo científico publicado en 2006

DNA Origami Nanoarrays for Multivalent Investigations of Cancer Cell Spreading with Nanoscale Spatial Resolution and Single-Molecule Control

artículo científico publicado en 2018

Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes.

artículo científico publicado en 2003

Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines

artículo científico publicado en 2010

Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus

artículo científico publicado en 2008

Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptide

artículo científico publicado en 2009

Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues

artículo científico publicado en 2008

Expression of αv integrins and vitronectin receptor identity in breast cancer cells ⬇️

artículo científico publicado el 1 de febrero de 1998

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

artículo científico publicado en 2007

Foot-and-mouth disease virus forms a highly stable, EDTA-resistant complex with its principal receptor, integrin alphavbeta6: implications for infectiousness

artículo científico publicado en 2007

Generation and characterization of a diabody targeting the αvβ6 integrin

artículo científico publicado en 2013

HS1-Associated Protein X-1 Regulates Carcinoma Cell Migration and Invasion via Clathrin-Mediated Endocytosis of Integrin αvβ6

article

Harnessing the power of foot-and-mouth-disease virus for targeting integrin alpha-v beta-6 for the therapy of cancer

High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.

artículo científico publicado en 2010

High-throughput in vivo screening of targeted molecular imaging agents

artículo científico publicado en 2009

In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.

artículo científico publicado en 2009

Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis.

artículo científico publicado en 2010

Influence of tumor-derived interleukin 1 on melanoma-endothelial cell interactions in vitro ⬇️

artículo científico publicado el 15 de septiembre de 1991

Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16 ⬇️

artículo científico publicado el 1 de agosto de 1997

Integrin trafficking and its role in cancer metastasis

artículo científico publicado en 2007

Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus

artículo científico publicado en 2020

Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment

scientific article published on 21 August 2019

Integrins as Therapeutic Targets: Successes and Cancers.

artículo científico publicado en 2017

Investigating in vitro and in vivo αvβ6 integrin receptor-targeting liposomal alendronate for combinatory γδ T cell immunotherapy.

artículo científico publicado en 2017

Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability

artículo científico publicado en 2003

Modulation of human stromelysin 3 promoter activity and gene expression by human breast cancer cells ⬇️

artículo científico publicado el 9 de octubre de 1997

Modulation of the urokinase-type plasminogen activator receptor by the beta6 integrin subunit.

artículo científico publicado en 2004

NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin αvβ6 ligand specificity

artículo científico publicado en 2012

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer.

artículo científico publicado en 2018

Pancreatic cancer organotypic cultures.

artículo científico publicado en 2010

Pharmacological Characterization of the αvβ6 Integrin Binding and Internalization Kinetics of the Foot-and-Mouth Disease Virus Derived Peptide A20FMDV2.

artículo científico publicado en 2016

Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis

artículo científico publicado en 2013

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch.

artículo científico publicado en 2017

Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control

scientific article published on 01 October 2019

Rapid solid phase synthesis and biodistribution of 18F-labelled linear peptides

artículo científico publicado en 2002

Rigidity sensing and adaptation through regulation of integrin types.

artículo científico publicado en 2014

S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells.

artículo científico publicado en 2012

Stromal features are predictive of disease mortality in oral cancer patients

artículo científico publicado en 2011

Structural guided scaffold phage display libraries as a source of bio-therapeutics

artículo científico publicado en 2013

Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality

artículo científico publicado en 2017

Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function.

artículo científico publicado en 2014

TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration?

artículo científico publicado en 2004

Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model

artículo científico publicado en 2009

Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?

artículo científico publicado en 2017

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells

artículo científico publicado en 2017

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells

artículo científico publicado en 2017

The ITGB6 gene: its role in experimental and clinical biology

scientific article

The Integrins α3β1and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells

artículo científico publicado en 2000

The Novel Oncolytic Adenoviral Mutant Ad5-3Δ-A20T Retargeted to αvβ6 Integrins Efficiently Eliminates Pancreatic Cancer Cells.

artículo científico publicado en 2018

The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9.

artículo científico publicado en 2004

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

scientific article published on 30 July 2019

The role of α9β1 integrin in modulating epithelial cell behaviour.

artículo científico publicado en 2011

Therapeutic targeting of integrin αvβ6 in breast cancer

artículo científico publicado en 2014

Transwell® Invasion Assays ⬇️

artículo científico publicado el 1 de enero de 2011

Tumor cell migration in three dimensions

artículo científico publicado en 2006

Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.

artículo científico publicado en 2010

Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alphavbeta6 expression with positron emission tomograp

artículo científico publicado en 2007

alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation

artículo científico publicado en 2008

αvβ6 Expression in myoepithelial cells: a novel marker for predicting DCIS progression with therapeutic potential

artículo científico publicado en 2014

Lista de obras de John F Marshall

A framework for the development of effective anti-metastatic agents

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

Activation status and function of the VLA-4 (α4β1) integrin expressed on human melanoma cell lines ⬇️

AlphaV integrins play an important role in myofibroblast differentiation

Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis

Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence

Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.

Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer

Correlative 3D Structured Illumination Microscopy and Single-Molecule Localization Microscopy for Imaging Cancer Invasion

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Current Perspectives on the Use of off the Shelf CAR-T/NK Cells for the Treatment of Cancer

Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion.

DNA Origami Nanoarrays for Multivalent Investigations of Cancer Cell Spreading with Nanoscale Spatial Resolution and Single-Molecule Control

Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes.

Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines

Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus

Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptide

Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues

Expression of αv integrins and vitronectin receptor identity in breast cancer cells ⬇️

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

Foot-and-mouth disease virus forms a highly stable, EDTA-resistant complex with its principal receptor, integrin alphavbeta6: implications for infectiousness

Generation and characterization of a diabody targeting the αvβ6 integrin

HS1-Associated Protein X-1 Regulates Carcinoma Cell Migration and Invasion via Clathrin-Mediated Endocytosis of Integrin αvβ6

Harnessing the power of foot-and-mouth-disease virus for targeting integrin alpha-v beta-6 for the therapy of cancer

High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.

High-throughput in vivo screening of targeted molecular imaging agents

In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.

Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis.

Influence of tumor-derived interleukin 1 on melanoma-endothelial cell interactions in vitro ⬇️

Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16 ⬇️

Integrin trafficking and its role in cancer metastasis

Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus

Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment

Integrins as Therapeutic Targets: Successes and Cancers.

Investigating in vitro and in vivo αvβ6 integrin receptor-targeting liposomal alendronate for combinatory γδ T cell immunotherapy.

Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability

Modulation of human stromelysin 3 promoter activity and gene expression by human breast cancer cells ⬇️

Modulation of the urokinase-type plasminogen activator receptor by the beta6 integrin subunit.

NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin αvβ6 ligand specificity

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer.

Pancreatic cancer organotypic cultures.

Pharmacological Characterization of the αvβ6 Integrin Binding and Internalization Kinetics of the Foot-and-Mouth Disease Virus Derived Peptide A20FMDV2.

Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch.

Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control

Rapid solid phase synthesis and biodistribution of 18F-labelled linear peptides

Rigidity sensing and adaptation through regulation of integrin types.

S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells.

Stromal features are predictive of disease mortality in oral cancer patients

Structural guided scaffold phage display libraries as a source of bio-therapeutics

Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality

Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function.

TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration?

Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model

Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells

The ITGB6 gene: its role in experimental and clinical biology

The Integrins α3β1and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells

The Novel Oncolytic Adenoviral Mutant Ad5-3Δ-A20T Retargeted to αvβ6 Integrins Efficiently Eliminates Pancreatic Cancer Cells.

The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9.

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

The role of α9β1 integrin in modulating epithelial cell behaviour.

Therapeutic targeting of integrin αvβ6 in breast cancer

Transwell® Invasion Assays ⬇️

Tumor cell migration in three dimensions

Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.

Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alphavbeta6 expression with positron emission tomograp

alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation

αvβ6 Expression in myoepithelial cells: a novel marker for predicting DCIS progression with therapeutic potential