Lista de obras - Michel Bernier - Dominio Público Uruguay

(R,R')-4'-methoxy-1-naphthylfenoterol targets GPR55-mediated ligand internalization and impairs cancer cell motility

artículo científico publicado en 2013

(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.

artículo científico publicado en 2014

A chemical cross-linking method for the analysis of binding partners of heat shock protein-90 in intact cells.

artículo científico publicado en 2012

A peptide-based protein-tyrosine phosphatase inhibitor specifically enhances insulin receptor function in intact cells

artículo científico publicado en 1996

A time to fast

scientific article published on 01 November 2018

Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3.

artículo científico publicado en 2010

Adipogenic signaling in rat white adipose tissue: modulation by aging and calorie restriction.

artículo científico publicado en 2007

Antitumor activity of (R,R')-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mouse

artículo científico publicado en 2013

Binding of manumycin A inhibits IkappaB kinase beta activity

artículo científico publicado en 2006

Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells ⬇️

artículo científico publicado el 8 de marzo de 2012

Cannabinoid receptor activation correlates with the proapoptotic action of the β2-adrenergic agonist (R,R')-4-methoxy-1-naphthylfenoterol in HepG2 hepatocarcinoma cells

artículo científico publicado en 2012

Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity

artículo científico publicado en 2011

D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression

artículo científico publicado en 2014

Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance

artículo científico publicado en 2021

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β<sub>2</sub> adrenergic agonist

artículo científico publicado en 2022

Determination of free and protein-bound glutathione in HepG2 cells using capillary electrophoresis with laser-induced fluorescence detection

artículo científico publicado en 2008

Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice

artículo científico publicado en 1999

Discrete region of the insulin receptor carboxyl terminus plays key role in insulin action

artículo científico publicado en 2000

Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

artículo científico publicado en 2020

Endocrine regulation of G-protein subunit production in an animal model of type 2 diabetes mellitus.

artículo científico publicado en 2001

Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease

artículo científico publicado en 2009

Filamin A expression correlates with proliferation and invasive properties of human metastatic melanoma tumors: implications for survival in patients.

artículo científico publicado en 2014

Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells.

artículo científico publicado en 2007

Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action.

artículo científico publicado en 1994

Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

artículo científico publicado en 2007

Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells.

artículo científico publicado en 2009

Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translation

artículo científico publicado en 2011

Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type

artículo científico publicado en 2007

Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities

artículo científico publicado en 2007

Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent.

artículo científico publicado en 2001

Interaction of filamin A with the insulin receptor alters insulin-dependent activation of the mitogen-activated protein kinase pathway.

artículo científico publicado en 2003

Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells

scientific journal article

Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells

artículo científico publicado en 2010

Ligand and protein fishing with heat shock protein 90 coated magnetic beads.

artículo científico publicado en 2008

Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2.

artículo científico publicado en 2014

Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice

scientific article published on 30 December 2018

Metformin improves healthspan and lifespan in mice

artículo científico publicado en 2013

Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein

artículo científico publicado en 2011

Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells

artículo científico publicado en 2013

Nucleotide Excision Repair Is Not Required for the Antiapoptotic Function of Insulin-like Growth Factor 1 ⬇️

artículo científico publicado el 15 de junio de 1998

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.

artículo científico publicado en 2012

Phosphatidylinositol 3-kinase requirement in activation of the ras/C-raf-1/MEK/ERK and p70(s6k) signaling cascade by the insulinomimetic agent vanadyl sulfate

artículo científico publicado en 1999

Processing of human choriogonadotropin and its receptors by cultured pig Leydig cells. Role of cyclic AMP and protein synthesis

artículo científico publicado en 1986

Pyrrolidine Dithiocarbamate Inhibits Interleukin-6 Signaling through Impaired STAT3 Activation and Association with Transcriptional Coactivators in Hepatocytes

artículo científico publicado en 2006

Pyrrolidine dithiocarbamate enhances hepatic glycogen synthesis and reduces FoxO1-mediated gene transcription in type 2 diabetic rats ⬇️

artículo científico publicado el 29 de noviembre de 2011

Regulation of glucose transporters and hexose uptake in 3T3-L1 adipocytes: glucagon-like peptide-1 and insulin interactions ⬇️

artículo científico publicado el 1 de diciembre de 1997

Regulation of gonadotropin receptors on cultured porcine Leydig and Sertoli cells: effect of potassium depletion

scientific article published on 01 June 1986

Resveratrol and Its Metabolites Bind to PPARs

artículo científico publicado en 2014

Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.

scientific article published on October 2013

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

artículo científico publicado en 2014

Resveratrol supplementation: Where are we now and where should we go?

artículo científico publicado en 2015

Reversible change in thiol redox status of the insulin receptor alpha-subunit in intact cells

scientific article published on 01 May 1999

Role of the pleckstrin homology domain of PLCgamma1 in its interaction with the insulin receptor

artículo científico publicado en 2003

S-glutathionylation impairs signal transducer and activator of transcription 3 activation and signaling.

artículo científico publicado en 2008

S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.

artículo científico publicado en 2011

SIRT1 synchs satellite cell metabolism with stem cell fate.

artículo científico publicado en 2015

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

artículo científico publicado en 2014

Sensing the insulin signaling pathway with an antibody array ⬇️

artículo científico publicado el 13 de octubre de 2009

The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet

artículo científico publicado en 2014

The biarylpyrazole compound AM251 alters mitochondrial physiology via proteolytic degradation of ERRα

artículo científico publicado en 2012

The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein

artículo científico publicado en 2011

The importance of the nine-amino acid C-terminal sequence of exendin-4 for binding to the GLP-1 receptor and for biological activity.

artículo científico publicado en 2003

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

artículo científico publicado en 2010

The search for antiaging interventions: from elixirs to fasting regimens

artículo científico publicado en 2014

Thiol-specific biotinylation of the insulin receptor in permeabilized cells enhances receptor function.

artículo científico publicado en 1995

Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor

artículo científico publicado en 2014

What is hydroxynorketamine and what can it bring to neurotherapeutics?

artículo científico publicado en 2014

Wnt5A activates the calpain-mediated cleavage of filamin A

artículo científico publicado en 2009

Lista de obras de Michel Bernier

(R,R')-4'-methoxy-1-naphthylfenoterol targets GPR55-mediated ligand internalization and impairs cancer cell motility

(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.

A chemical cross-linking method for the analysis of binding partners of heat shock protein-90 in intact cells.

A peptide-based protein-tyrosine phosphatase inhibitor specifically enhances insulin receptor function in intact cells

A time to fast

Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3.

Adipogenic signaling in rat white adipose tissue: modulation by aging and calorie restriction.

Antitumor activity of (R,R')-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mouse

Binding of manumycin A inhibits IkappaB kinase beta activity

Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells ⬇️

Cannabinoid receptor activation correlates with the proapoptotic action of the β2-adrenergic agonist (R,R')-4-methoxy-1-naphthylfenoterol in HepG2 hepatocarcinoma cells

Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity

D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression

Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β<sub>2</sub> adrenergic agonist

Determination of free and protein-bound glutathione in HepG2 cells using capillary electrophoresis with laser-induced fluorescence detection

Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice

Discrete region of the insulin receptor carboxyl terminus plays key role in insulin action

Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

Endocrine regulation of G-protein subunit production in an animal model of type 2 diabetes mellitus.

Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease

Filamin A expression correlates with proliferation and invasive properties of human metastatic melanoma tumors: implications for survival in patients.

Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells.

Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action.

Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells.

Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translation

Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type

Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities

Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent.

Interaction of filamin A with the insulin receptor alters insulin-dependent activation of the mitogen-activated protein kinase pathway.

Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells

Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells

Ligand and protein fishing with heat shock protein 90 coated magnetic beads.

Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2.

Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice

Metformin improves healthspan and lifespan in mice

Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein

Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells

Nucleotide Excision Repair Is Not Required for the Antiapoptotic Function of Insulin-like Growth Factor 1 ⬇️

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.

Phosphatidylinositol 3-kinase requirement in activation of the ras/C-raf-1/MEK/ERK and p70(s6k) signaling cascade by the insulinomimetic agent vanadyl sulfate

Processing of human choriogonadotropin and its receptors by cultured pig Leydig cells. Role of cyclic AMP and protein synthesis

Pyrrolidine Dithiocarbamate Inhibits Interleukin-6 Signaling through Impaired STAT3 Activation and Association with Transcriptional Coactivators in Hepatocytes

Pyrrolidine dithiocarbamate enhances hepatic glycogen synthesis and reduces FoxO1-mediated gene transcription in type 2 diabetic rats ⬇️

Regulation of glucose transporters and hexose uptake in 3T3-L1 adipocytes: glucagon-like peptide-1 and insulin interactions ⬇️

Regulation of gonadotropin receptors on cultured porcine Leydig and Sertoli cells: effect of potassium depletion

Resveratrol and Its Metabolites Bind to PPARs

Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

Resveratrol supplementation: Where are we now and where should we go?

Reversible change in thiol redox status of the insulin receptor alpha-subunit in intact cells

Role of the pleckstrin homology domain of PLCgamma1 in its interaction with the insulin receptor

S-glutathionylation impairs signal transducer and activator of transcription 3 activation and signaling.

S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.

SIRT1 synchs satellite cell metabolism with stem cell fate.

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

Sensing the insulin signaling pathway with an antibody array ⬇️

The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet

The biarylpyrazole compound AM251 alters mitochondrial physiology via proteolytic degradation of ERRα

The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein

The importance of the nine-amino acid C-terminal sequence of exendin-4 for binding to the GLP-1 receptor and for biological activity.

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

The search for antiaging interventions: from elixirs to fasting regimens

Thiol-specific biotinylation of the insulin receptor in permeabilized cells enhances receptor function.

Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor

What is hydroxynorketamine and what can it bring to neurotherapeutics?

Wnt5A activates the calpain-mediated cleavage of filamin A