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Lista de obras de Neil E Kay

A comprehensive evaluation of the prognostic significance of 13q deletions in patients with B-chronic lymphocytic leukaemia

artículo científico publicado en 2009

A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia

artículo científico publicado en 2019

A novel method for analysis of human T cell repertoires by real-time PCR.

artículo científico publicado en 2014

A progression-risk score to predict treatment-free survival for early stage chronic lymphocytic leukemia patients.

artículo científico publicado en 2015

A randomized phase II trial comparing chemoimmunotherapy with or without bevacizumab in previously untreated patients with chronic lymphocytic leukemia

artículo científico publicado en 2016

A recombinant IL-4-Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells.

artículo científico publicado en 2005

A two-stage evaluation of genetic variation in immune and inflammation genes with risk of non-Hodgkin lymphoma identifies new susceptibility locus in 6p21.3 region

artículo científico publicado en 2012

Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival

artículo científico publicado en 2002

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells

artículo científico publicado en 2009

Abnormal T cell function in early-stage chronic lymphocytic leukemia (CLL) patients

artículo científico publicado en 1986

Abnormal erythrocyte metabolism in hepatic disease ⬇️

artículo científico publicado el 1 de diciembre de 1975

Abnormal erythrocyte metabolism in hepatic disease: Effects of NADP repletion ⬇️

artículo científico publicado el 1 de enero de 1979

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants

artículo científico publicado en 2014

Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine

artículo científico publicado en 2004

Addition of granulocyte macrophage colony stimulating factor does not improve response to early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab

artículo científico publicado en 2012

Addition of venetoclax at time of progression in ibrutinib-treated patients with chronic lymphocytic leukemia: Combination therapy to prevent ibrutinib flare

scientific article published on 13 December 2019

Advances in the understanding of biology and prognosis in chronic lymphocytic leukemia

artículo científico publicado en 2004

Age at diagnosis and the utility of prognostic testing in patients with chronic lymphocytic leukemia

artículo científico publicado en 2010

Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study.

artículo científico publicado en 2017

Akt inhibitor MK2206 selectively targets CLL B-cell receptor induced cytokines, mobilizes lymphocytes and synergizes with bendamustine to induce CLL apoptosis

artículo científico publicado en 2013

Altered T cell repertoire usage in CD4 and CD8 subsets of multiple myeloma patients, a Study of the Eastern Cooperative Oncology Group (E9487).

artículo científico publicado en 1999

Analysis of B-lymphoid malignancies using allele-specific polymerase chain reaction: a technique for sequential quantitation of residual disease

scientific article published on 01 December 1991

Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia

artículo científico publicado en 2001

Analysis of racial variations in disease characteristics, treatment patterns, and outcomes of patients with chronic lymphocytic leukemia

artículo científico publicado en 2016

Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity.

artículo científico publicado en 2018

Angiogenesis in B-chronic lymphocytic leukemia

scientific article published on 01 June 2001

Angiogenesis in B-chronic lymphocytic leukemia

artículo científico publicado en 2001

Angiogenesis revisited in CLL

scientific article published on 16 May 2007

Anthropometric Characteristics, Physical Activity, and Risk of Non-Hodgkin's Lymphoma Subtypes and B-Cell Chronic Lymphocytic Leukemia: A Prospective Study

artículo científico publicado en 2002

Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia

artículo científico publicado en 2011

Association of elevated serumfree light chains with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis

artículo científico publicado en 2019

Association of health-related quality of life with gender in patients with B-cell chronic lymphocytic leukemia

artículo científico publicado en 2013

Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.

artículo científico publicado en 2018

Atrial fibrillation in patients with chronic lymphocytic leukemia (CLL) treated with ibrutinib: risk prediction, management, and clinical outcomes

artículo científico publicado en 2020

Atrial fibrillation in patients with chronic lymphocytic leukemia (CLL).

artículo científico publicado en 2016

Autoimmune complications in chronic lymphocytic leukaemia (CLL).

artículo científico publicado en 2010

Autoimmune cytopenia in chronic lymphocytic leukemia/small lymphocytic lymphoma: changes in clinical presentation and prognosis

artículo científico publicado en 2009

Autoimmune cytopenias in patients with chronic lymphocytic leukaemia treated with ibrutinib in routine clinical practice at an academic medical centre

artículo científico publicado en 2018

Axl activates fibroblast growth factor receptor pathway to potentiate survival signals in B-cell chronic lymphocytic leukemia cells

artículo científico publicado en 2015

B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules

artículo científico publicado en 2002

B-CLL: is the enigma of disease heterogeneity about to be revealed?

artículo científico publicado en 2002

B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome

artículo científico publicado en 2008

B-cell prolymphocytic leukemia has 3 subsets

scientific article published on 01 November 2019

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

artículo científico publicado en 2014

Benefits of minimal residual disease negativity in the therapy of chronic lymphocytic leukemia

artículo científico publicado en 2008

Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression

artículo científico publicado en 2009

Biologic agent activity in chronic lymphocytic leukemia: a framework for future therapies ⬇️

artículo científico publicado el 1 de marzo de 2011

Biological and prognostic significance of interphase fluorescence in situ hybridization detection of chromosome 13 abnormalities (delta13) in multiple myeloma: an eastern cooperative oncology group study

artículo científico publicado en 2002

Biological evaluation of CpG stimulation of normal human B‐cells: implications for B‐cell biology and cytogenetic analysis of CLL B‐cells ⬇️

artículo científico publicado el 17 de febrero de 2011

Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an "angiogenic switch".

artículo científico publicado en 2007

Bone marrow hematopoietic dysfunction in untreated chronic lymphocytic leukemia patients

artículo científico publicado en 2018

Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance

artículo científico publicado en 2011

Brief report: natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic leukemia

artículo científico publicado en 2009

CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation.

artículo científico publicado en 2005

CD49d associates with nodal presentation and subsequent development of lymphadenopathy in patients with chronic lymphocytic leukaemia

artículo científico publicado en 2017

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

artículo científico publicado en 2008

CD5-positive chronic B-cell lymphoproliferative disorders: diagnosis and prognosis of a heterogeneous disease entity.

artículo científico publicado en 2010

CGH protocols: chronic lymphocytic leukemia

scientific article published on 01 January 2013

CLL B cells with a bimodal CD38 expression pattern: persistence of bimodal populations despite effective therapy for B-CLL ⬇️

artículo científico publicado el 1 de enero de 2004

Calibration standards for antigen quantification in CLL

scientific article published on 01 March 2008

Cell-cell interaction in human granulopoiesis: role of T lymphocytes

artículo científico publicado en 1981

Chemoimmunotherapy Is Not Dead Yet in Chronic Lymphocytic Leukemia

artículo científico publicado en 2017

Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

scientific article published on 01 April 2003

Chronic lymphocytic leukemia

artículo científico publicado en 2002

Chronic lymphocytic leukemia (CLL) risk is mediated by multiple enhancer variants within CLL risk loci

scientific article published on 03 August 2020

Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy

Chronic lymphocytic leukemia in 2020: a surfeit of riches?

scientific article published on 11 May 2020

Chronic lymphocytic leukemia in association with a second lymphoproliferative disorder: response to chemotherapy in two cases

artículo científico publicado en 1979

Chronic lymphocytic leukemia in young (≤ 55 years) patients: a comprehensive analysis of prognostic factors and outcomes

artículo científico publicado en 2013

Chronic lymphocytic leukemia international prognostic index: a systematic review and meta-analysis.

artículo científico publicado en 2017

Chronic lymphocytic leukemia is associated with decreased survival of patients with malignant melanoma and Merkel cell carcinoma in a SEER population-based study

artículo científico publicado en 2012

Chronic lymphocytic leukemia: biology and current treatment

artículo científico publicado en 2007

Chronic lymphocytic leukemia: current and emerging treatment approaches

artículo científico publicado en 2006

Chronic lymphocytic leukemia: recommendations

artículo científico publicado en 1989

Cimetidine modulates natural killer cell function of patients with chronic lymphocytic leukemia

scientific article published on 01 April 1987

Circulating endothelial cells in chronic lymphocytic leukemia: more evidence of disturbed angiogenesis.

artículo científico publicado en 2009

Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression

artículo científico publicado en 2009

Clinical characteristics and outcomes of Richter transformation: experience of 204 patients from a single center

scientific article published on 13 June 2019

Clinical effects of oral green tea extracts in four patients with low grade B-cell malignancies

artículo científico publicado en 2005

Clinical trial of recombinant leukocyte A interferon as initial therapy for favorable histology non-Hodgkin's lymphomas and chronic lymphocytic leukemia. An Eastern Cooperative Oncology Group pilot study

artículo científico publicado en 1986

Cohort Profile: The Lymphoma Specialized Program of Research Excellence (SPORE) Molecular Epidemiology Resource (MER) Cohort Study.

artículo científico publicado en 2017

Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia

artículo científico publicado en 2007

Combination therapies for previously untreated CLL

scientific article published on 01 July 2007

Common occurrence of monoclonal B-cell lymphocytosis among members of high-risk CLL families

artículo científico publicado en 2010

Common variants within 6p21.31 locus are associated with chronic lymphocytic leukaemia and, potentially, other non-Hodgkin lymphoma subtypes

artículo científico publicado en 2012

Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia

artículo científico publicado en 2012

Community-based phase II trial of PCR for CLL/SLL patients

artículo científico publicado en 2007

Comorbid conditions and survival in unselected, newly diagnosed patients with chronic lymphocytic leukemia

artículo científico publicado en 2008

Complete remission induction with combined VBMCP chemotherapy and interferon (rIFN alpha 2b) in patients with multiple myeloma

artículo científico publicado en 1996

Complete response in multiple myeloma: clinical trial E9486, an Eastern Cooperative Oncology Group study not involving stem cell transplantation

scientific article published on 01 May 2006

Comprehensive management of the CLL patient: a holistic approach

scientific article published on January 2007

Computational identification of CDR3 sequence archetypes among immunoglobulin sequences in chronic lymphocytic leukemia

artículo científico publicado en 2008

Controversies in the front-line management of chronic lymphocytic leukemia

artículo científico publicado en 2008

Correction: potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis.

artículo científico publicado en 2013

Critical signal transduction pathways in CLL.

artículo científico publicado en 2013

Cumulative experience and long term follow-up of pentostatin-based chemoimmunotherapy trials for patients with chronic lymphocytic leukemia

artículo científico publicado en 2018

Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG.

scientific article published on February 2009

Cytogenetic Findings and Survival in B-cell Chronic Lymphocytic Leukemia. Second IWCCLL Compilation of Data on 662 Patients

artículo científico publicado en 1991

Cytogenetic abnormalities can change during the course of the disease process in chronic lymphocytic leukemia

artículo científico publicado en 2006

Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways

artículo científico publicado en 2006

De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience

artículo científico publicado en 2009

Deep sequencing identifies genetic heterogeneity and recurrent convergent evolution in chronic lymphocytic leukemia

artículo científico publicado en 2014

Defective T cell responsiveness in chronic lymphocytic leukemia: analysis of activation events.

artículo científico publicado en 1986

Defective expression of T cell antigens in chronic lymphocytic leukaemia: relationship to T cell dysfunction

artículo científico publicado en 1984

Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q arm or monosomy.

artículo científico publicado en 2001

Delineation of clinical and biological factors associated with cutaneous squamous cell carcinoma amongst chronic lymphocytic leukemia patients

artículo científico publicado en 2020

Design and validity of a clinic-based case-control study on the molecular epidemiology of lymphoma

artículo científico publicado en 2011

Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients ⬇️

artículo científico publicado el 1 de octubre de 1992

Development of a comprehensive prognostic index for patients with chronic lymphocytic leukemia

artículo científico publicado en 2014

Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia

artículo científico publicado en 2019

Diagnostic criteria for monoclonal B-cell lymphocytosis

artículo científico publicado en 2005

Differentiation of chronic lymphocytic leukemia B cells into immunoglobulin secreting cells decreases LEF-1 expression

artículo científico publicado en 2011

Diffuse large B-cell lymphoma (Richter syndrome) in patients with chronic lymphocytic leukaemia (CLL): a cohort study of newly diagnosed patients

artículo científico publicado en 2013

Direct and complement dependent cytotoxicity in CLL cells from patients with high-risk early-intermediate stage chronic lymphocytic leukemia (CLL) treated with alemtuzumab and rituximab

artículo científico publicado en 2008

Disease Flare During Temporary Interruption of Ibrutinib Therapy in Patients with Chronic Lymphocytic Leukemia

artículo científico publicado en 2020

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

artículo científico publicado en 2009

Dynamics of microvesicle generation in B-cell chronic lymphocytic leukemia: implication in disease progression.

scientific article published on 02 August 2016

Dysregulated angiogenesis in B-chronic lymphocytic leukemia: morphologic, immunohistochemical, and flow cytometric evidence

artículo científico publicado en 2008

Early progression of disease as a predictor of survival in chronic lymphocytic leukemia

artículo científico publicado en 2017

Early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab

artículo científico publicado en 2008

Elevated serum B-lymphocyte stimulator levels in patients with familial lymphoproliferative disorders.

artículo científico publicado en 2006

Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival

artículo científico publicado en 2015

Establishment and characterization of a subclone (U-937-AG) from a permanent human monocyte cell line

artículo científico publicado en 1984

Experimental designs for array comparative genomic hybridization technology

artículo científico publicado en 2013

Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2007

Expression of the chemokine receptors CXCR4 and CCR7 and disease progression in B-cell chronic lymphocytic leukemia/ small lymphocytic lymphoma

artículo científico publicado en 2004

Extramedullary chronic lymphocytic leukemia: systematic analysis of cases reported between 1975 and 2012.

artículo científico publicado en 2013

Familial chronic lymphocytic leukemia: what does it mean to me?

artículo científico publicado en 2009

Fluorescent-labeled DNA probes applied to novel biological aspects of B-cell chronic lymphocytic leukemia

artículo científico publicado en 2005

Frequent clonal abnormalities of chromosome band 13q14 in B-cell chronic lymphocytic leukemia: multiple clones, subclones, and nonclonal alterations in 82 midwestern patients

scientific article published on 01 June 1992

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

artículo científico publicado en 2018

GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma

artículo científico publicado en 2011

Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma

artículo científico publicado en 2006

Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia

artículo científico publicado en 2013

Genetic susceptibility variants for chronic lymphocytic leukemia

artículo científico publicado en 2010

Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma

artículo científico publicado en 2007

Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma

artículo científico publicado en 2008

Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL

scientific journal article

Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

artículo científico publicado en 2013

Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.

artículo científico publicado en 2010

Genomic characterization of high-count MBL cases indicates that early detection of driver mutations and subclonal expansion are predictors of adverse clinical outcome

artículo científico publicado en 2016

Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma

artículo científico publicado en 2010

Guidelines for clinical protocols for chronic lymphocytic leukemia: recommendations of the National Cancer Institute-sponsored working group

artículo científico publicado en 1988

Hematologist/oncologist disease-specific expertise and survival: lessons from chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).

artículo científico publicado en 2011

Heterogeneity of CD5 Membrane Expression on B-Chronic Lymphocytic Leukemia Cells

artículo científico publicado en 1991

High prevalence of monoclonal gammopathy among patients with warm autoimmune hemolytic anemia

artículo científico publicado en 2017

High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia

artículo científico publicado en 2016

Highlights from the 46 th annual meeting of the American Society of Hematology

artículo científico publicado en 2005

Hodgkin transformation of chronic lymphocytic leukemia: Incidence, outcomes, and comparison to de novo Hodgkin lymphoma.

artículo científico publicado en 2015

How I treat autoimmune hemolytic anemia.

artículo científico publicado en 2017

How we treat Richter syndrome

artículo científico publicado en 2014

Human T-cell function in experimental ascorbic acid deficiency and spontaneous scurvy

scientific article published on 01 July 1982

Hypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia: Natural history, clinical correlates, and outcomes

artículo científico publicado en 2015

IGH translocations in chronic lymphocytic leukemia: Clinicopathologic features and clinical outcomes

artículo científico publicado en 2019

IL-4 biology: impact on normal and leukemic CLL B cells

artículo científico publicado en 2003

Ibrutinib restores immune cell numbers and function in first-line and relapsed/refractory chronic lymphocytic leukemia

scientific article published on 11 August 2020

Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia

artículo científico publicado en 2014

Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

artículo científico publicado en 2019

Identification of a global gene expression signature of B-chronic lymphocytic leukemia.

artículo científico publicado en 2003

Identification of recurrent truncated DDX3X mutations in chronic lymphocytic leukaemia.

artículo científico publicado en 2014

Immune-mediated hemolytic anemia and thrombocytopenia in clonal B-cell disorders: a review

scientific article published on 01 October 2018

Immunoglobulin diversity gene usage predicts unfavorable outcome in a subset of chronic lymphocytic leukemia patients

artículo científico publicado en 2008

Immunophenotypic and gene expression analysis of monoclonal B-cell lymphocytosis shows biologic characteristics associated with good prognosis CLL.

artículo científico publicado en 2011

Impact of ibrutinib and idelalisib on the pharmaceutical cost of treating chronic lymphocytic leukemia at the individual and societal levels

artículo científico publicado en 2015

Improvement in Parameters of Hematologic and Immunologic Function and Patient Well-being in the Phase III RESONATE Study of Ibrutinib Versus Ofatumumab in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

scientific article published on 18 August 2018

Incidence and risk of tumor lysis syndrome in patients with relapsed chronic lymphocytic leukemia (CLL) treated with venetoclax in routine clinical practice

scientific article published on 25 May 2020

Incidence of chronic lymphocytic leukemia and high-count monoclonal B-cell lymphocytosis using the 2008 guidelines

artículo científico publicado en 2014

Infectious complications among individuals with clinical monoclonal B-cell lymphocytosis (MBL): a cohort study of newly diagnosed cases compared to controls

artículo científico publicado en 2012

Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells

artículo científico publicado en 2007

Interferon in the Treatment of Refractory Multiple Myeloma: An Eastern Cooperative Oncology Group Study

artículo científico publicado en 1990

Interphase fluorescence in situ hybridization with an IGH probe is important in the evaluation of patients with a clinical diagnosis of chronic lymphocytic leukaemia.

artículo científico publicado en 2005

Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells

artículo científico publicado en 2003

Is flow cytometric DNA content hypodiploidy prognostic in multiple myeloma?

artículo científico publicado en 1999

Is unmeasurable residual disease (uMRD) the best surrogate endpoint for clinical trials, regulatory approvals and therapy decisions in chronic lymphocytic leukaemia (CLL)?

artículo científico publicado en 2022

KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival

artículo científico publicado en 2019

Karyotype evolution on fluorescent in situ hybridization analysis is associated with short survival in patients with chronic lymphocytic leukemia and is related to CD49d expression

artículo científico publicado en 2008

LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis

artículo científico publicado en 2010

Large granular lymphocytes from B-chronic lymphocytic leukemia patients inhibit normal B cell proliferation

artículo científico publicado en 1989

Large-scale analysis of DNA methylation in chronic lymphocytic leukemia

artículo científico publicado en 2009

Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia

artículo científico publicado en 2017

Leukemic Extracellular Vesicles Induce Chimeric Antigen Receptor T Cell Dysfunction in Chronic Lymphocytic Leukemia

artículo científico publicado en 2020

Liver dysfunction in chronic lymphocytic leukemia: Prevalence, outcomes, and pathological findings.

artículo científico publicado en 2017

Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL).

artículo científico publicado en 2013

Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.

artículo científico publicado en 2012

Loss of TP53 is due to rearrangements involving chromosome region 17p10 approximately p12 in chronic lymphocytic leukemia

scientific article published on 01 June 2006

Lymphoblastic transformation of myelodysplastic syndrome

artículo científico publicado en 1986

Lymphocytotoxic T lymphocytes in a patient with B-chronic lymphocytic leukemia and pure red cell aplasia

artículo científico publicado en 1985

MBL and MoBL - Response to Ziegler-Heitbrock

MBL or CLL: which classification best categorizes the clinical course of patients with an absolute lymphocyte count >or= 5 x 10(9) L(-1) but a B-cell lymphocyte count <5 x 10(9) L(-1)?

artículo científico publicado en 2008

Maintenance therapy for B-chronic lymphocytic leukemia

artículo científico publicado en 2011

Management of patients with chronic lymphocytic leukemia with a high risk of adverse outcome: the Mayo Clinic approach

artículo científico publicado en 2011

Mapping of the IRF8 gene identifies a 3'UTR variant associated with risk of chronic lymphocytic leukemia but not other common non-Hodgkin lymphoma subtypes

artículo científico publicado en 2013

Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab

artículo científico publicado en 2008

Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia

artículo científico publicado en 2016

Metaphase cells with normal G-bands have cryptic interstitial deletions in 13q14 detectable by fluorescence in situ hybridization in B-cell chronic lymphocytic leukemia.

artículo científico publicado en 2006

Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features

artículo científico publicado en 2007

Microvesicles in CLL: predictor of disease progression/relapse ⬇️

artículo científico publicado en 2017

Monoclonal B-cell lymphocytosis is characterized by mutations in CLL putative driver genes and clonal heterogeneity many years before disease progression

artículo científico publicado en 2014

Monoclonal B-cell lymphocytosis: update on diagnosis, clinical outcome, and counseling

artículo científico publicado en 2013

Monoclonal and polyclonal serum free light chains and clinical outcome in chronic lymphocytic leukemia

artículo científico publicado en 2011

Monocyte-erythrocyte interaction in vitro in immune hemolytic anemias .

artículo científico publicado en 1977

Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients.

artículo científico publicado en 2002

N9986: a phase II trial of thalidomide in patients with relapsed chronic lymphocytic leukemia

artículo científico publicado en 2009

Narrative review: initial management of newly diagnosed, early-stage chronic lymphocytic leukemia

artículo científico publicado en 2006

National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment

artículo científico publicado en 1996

Neuropilin-1 is expressed by chronic lymphocytic leukemia B cells

artículo científico publicado en 2008

Novel targeted agents and the need to refine clinical end points in chronic lymphocytic leukemia

artículo científico publicado en 2012

Ofatumumab monotherapy as a consolidation strategy in patients with previously untreated chronic lymphocytic leukaemia: a phase 2 trial

artículo científico publicado en 2016

Ofatumumab-based chemoimmunotherapy is effective and well tolerated in patients with previously untreated chronic lymphocytic leukemia (CLL).

artículo científico publicado en 2013

Outcomes of a large cohort of individuals with clinically ascertained high-count monoclonal B-cell lymphocytosis

artículo científico publicado en 2018

Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL.

artículo científico publicado en 2017

Pentostatin and rituximab therapy for previously untreated patients with B-cell chronic lymphocytic leukemia

artículo científico publicado en 2010

Pentostatin treatment combinations in chronic lymphocytic leukemia

artículo científico publicado en 2009

Pentostatin, Cyclophosphamide, and Rituximab Followed by Alemtuzumab for Relapsed or Refractory Chronic Lymphocytic Leukemia: A Phase 2 Trial of the ECOG-Acrin Cancer Research Group (E2903)

scientific article published on 23 July 2019

Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: a phase I/II study by the Eastern Cooperative Oncology Group study E1488.

artículo científico publicado en 2004

Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia

artículo científico publicado en 2007

Percentage of smudge cells on routine blood smear predicts survival in chronic lymphocytic leukemia

artículo científico publicado en 2009

Pharmacovigilance during ibrutinib therapy for chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) in routine clinical practice

artículo científico publicado en 2016

Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia

artículo científico publicado en 2012

Phase I clinical trial of CpG oligonucleotide 7909 (PF-03512676) in patients with previously treated chronic lymphocytic leukemia

artículo científico publicado en 2011

Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia

artículo científico publicado en 2009

Phase II study of interleukin-12 for treatment of plateau phase multiple myeloma (E1A96): a trial of the Eastern Cooperative Oncology Group

artículo científico publicado en 2009

Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia ⬇️

artículo científico publicado el 5 de noviembre de 2010

Plasmablastic morphology--an independent prognostic factor with clinical and laboratory correlates: Eastern Cooperative Oncology Group (ECOG) myeloma trial E9486 report by the ECOG Myeloma Laboratory Group

scientific article published on 01 April 1998

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch

artículo científico publicado en 2010

Potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis

artículo científico publicado en 2007

Precancer Atlas to Drive Precision Prevention Trials.

artículo científico publicado en 2017

Predicting clinical outcome in B-chronic lymphocytic leukemia

artículo científico publicado en 2012

Predictive value of the CLL-IPI in CLL patients receiving chemo-immunotherapy as first-line treatment

artículo científico publicado en 2018

Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy

artículo científico publicado en 2020

Pretreatment angiogenic cytokines predict response to chemoimmunotherapy in patients with chronic lymphocytic leukaemia

artículo científico publicado en 2009

Prevalence and Overall Survival of Low Count Monoclonal B-Cell Lymphocytosis (LC-MBL): A Screening Study of 8,297 Individuals from the Mayo Clinic Biobank

Production of erythroid potentiating factor(s) by a human monocytic cell line

artículo científico publicado en 1981

Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL ⬇️

artículo científico publicado el 23 de octubre de 2003

Prognostic Testing Patterns and Outcomes of Chronic Lymphocytic Leukemia Patients Stratified by Fluorescence In Situ Hybridization/Cytogenetics: A Real-world Clinical Experience in the Connect CLL Registry

artículo científico publicado en 2017

Prognostic factors in chronic lymphocytic leukemia

artículo científico publicado en 2007

Prognostic importance of T and NK-cells in a consecutive series of newly diagnosed patients with chronic lymphocytic leukaemia

scientific article published on April 2008

Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations

scientific article published on 17 May 2019

Prognostic significance of the S-phase fraction of light-chain-restricted cytoplasmic immunoglobulin (cIg) positive plasma cells in patients with newly diagnosed multiple myeloma enrolled on Eastern Cooperative Oncology Group treatment trial E9486

artículo científico publicado en 1999

Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia

artículo científico publicado en 2013

Prognostic value of serum markers of bone metabolism in untreated multiple myeloma patients

article

Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy

artículo científico publicado en 2010

Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia.

artículo científico publicado en 2006

Protein expression profiling of CLL B cells using replicate off-line strong cation exchange chromatography and LC-MS/MS

artículo científico publicado en 2005

Purine analogue-based chemotherapy regimens for patients with previously untreated B-chronic lymphocytic leukemia

artículo científico publicado en 2006

Quality of life in chronic lymphocytic leukemia: an international survey of 1482 patients.

artículo científico publicado en 2007

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia

artículo científico publicado en 2012

Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents

artículo científico publicado en 2005

Rapid disease progression following discontinuation of ibrutinib in patients with chronic lymphocytic leukemia treated in routine clinical practice

artículo científico publicado en 2019

Real-world clinical experience in the Connect® chronic lymphocytic leukaemia registry: a prospective cohort study of 1494 patients across 199 US centres.

artículo científico publicado en 2016

Reasons for initiation of treatment and predictors of response for patients with Rai stage 0/1 chronic lymphocytic leukemia (CLL) receiving first-line therapy: an analysis of the Connect® CLL cohort study

artículo científico publicado en 2018

Reconstitution of innate immunity in B-chronic lymphocytic leukemia: time to reconsider the possibilities ⬇️

artículo científico publicado el 1 de octubre de 2003

Recurrent Chromosome Abnormalities Define Nonoverlapping Unique Subgroups of Tumors in Patients With Chronic Lymphocytic Leukemia and Known Karyotypic Abnormalities

artículo científico publicado en 2013

Relationship between co-morbidities at diagnosis, survival and ultimate cause of death in patients with chronic lymphocytic leukaemia (CLL): a prospective cohort study.

artículo científico publicado en 2017

Relationship of blood monocytes with chronic lymphocytic leukemia aggressiveness and outcomes: a multi-institutional study

artículo científico publicado en 2016

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

artículo científico publicado en 2008

Renal complications in chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis: the Mayo Clinic experience

artículo científico publicado en 2015

Renal insufficiency is an independent prognostic factor in patients with chronic lymphocytic leukemia

artículo científico publicado en 2016

Reply to S. Opat et al

artículo científico publicado en 2017

Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia

artículo científico publicado en 2007

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes

artículo científico publicado en 2009

Risk of non-hematologic cancer in individuals with high-count monoclonal B-cell lymphocytosis

artículo científico publicado en 2015

Risk of serious infection among individuals with and without low count monoclonal B-cell lymphocytosis (MBL)

artículo científico publicado en 2020

Role of long non-coding RNAs in disease progression of early stage unmutated chronic lymphocytic leukemia

Room for improvement: immunizations for patients with monoclonal B-cell lymphocytosis or chronic lymphocytic leukemia.

artículo científico publicado en 2014

Secondary abnormalities of chromosome 6q in B-cell chronic lymphocytic leukemia: a sequential study of karyotypic instability in 51 patients

artículo científico publicado en 1998

Sequential phenotyping of myeloma patients on chemotherapy: persistence of activated T-cells and natural killer cells

scientific article published on 01 January 1995

Serum-free light chain-a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia.

artículo científico publicado en 2007

Severe zinc deficiency in humans: association with a reversible T-lymphocyte dysfunction

artículo científico publicado en 1981

Simultaneous presentation of relapsing Hodgkin's disease and treatment-related non-Hodgkin's lymphoma

scientific article published on 01 January 1985

SphK1 inhibitor potentiates the anti-cancer effect of EGCG on leukaemia cells.

artículo científico publicado en 2016

Sphingosine Kinase-1 Protects Multiple Myeloma from Apoptosis Driven by Cancer-Specific Inhibition of RTKs.

artículo científico publicado en 2015

Standardization of fluorescence in situ hybridization studies on chronic lymphocytic leukemia (CLL) blood and marrow cells by the CLL Research Consortium ⬇️

artículo científico publicado el 1 de diciembre de 2010

Statin and non-steroidal anti-inflammatory drug use in relation to clinical outcome among patients with Rai stage 0 chronic lymphocytic leukemia

artículo científico publicado en 2010

Stimulation of chronic lymphocytic leukemia cells with CpG oligodeoxynucleotide gives consistent karyotypic results among laboratories: a CLL Research Consortium (CRC) Study ⬇️

artículo científico publicado el 1 de diciembre de 2010

Survival of patients with clinically identified monoclonal B-cell lymphocytosis (MBL) relative to the age- and sex-matched general population

scientific article published on 12 August 2011

Susceptibility genes and B-chronic lymphocytic leukaemia

artículo científico publicado en 2007

T-cell abnormalities in patients with chronic lymphocytic leukemia.

artículo científico publicado en 2006

T-cell subpopulations in chronic lymphocytic leukemia: abnormalities in distribtuion and in in vitro receptor maturation ⬇️

artículo científico publicado el 1 de agosto de 1979

T-cell subpopulations in multiple myeloma: correlation with clinical disease status

artículo científico publicado en 1981

Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors

artículo científico publicado en 2015

The Connect CLL Registry: final analysis of 1494 patients with chronic lymphocytic leukemia across 199 US sites

scientific article published on 01 April 2020

The Dohner fluorescence in situ hybridization prognostic classification of chronic lymphocytic leukaemia (CLL): the CLL Research Consortium experience

artículo científico publicado en 2016

The HELIOS trial protocol: a phase III study of ibrutinib in combination with bendamustine and rituximab in relapsed/refractory chronic lymphocytic leukemia

artículo científico publicado en 2015

The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells

artículo científico publicado en 2013

The angiogenic status of B-CLL B cells: role of the VEGF receptors

scientific article published on 01 March 2004

The chronic lymphocytic leukemia international prognostic index predicts time to first treatment in early CLL: Independent validation in a prospective cohort of early stage patients.

artículo científico publicado en 2016

The clinical and biologic importance of neovascularization and angiogenic signaling pathways in chronic lymphocytic leukemia

artículo científico publicado en 2006

The efficacy of ibrutinib in the treatment of Richter syndrome

artículo científico publicado en 2015

The emerging role of ofatumumab in the treatment of chronic lymphocytic leukemia

artículo científico publicado en 2011

The impact of dose modification and temporary interruption of ibrutinib on outcomes of chronic lymphocytic leukemia patients in routine clinical practice

scientific article published on 18 March 2020

The impact of race, ethnicity, age and sex on clinical outcome in chronic lymphocytic leukemia: a comprehensive Surveillance, Epidemiology, and End Results analysis in the modern era

artículo científico publicado en 2014

The influential T cell in B-cell neoplasms ⬇️

artículo científico publicado el 1 de diciembre de 1983

The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy ⬇️

artículo científico publicado el 6 de diciembre de 2010

The physician-patient relationship and quality of life: lessons from chronic lymphocytic leukemia

artículo científico publicado en 2008

The prognostic significance of cytopenia in chronic lymphocytic leukaemia/small lymphocytic lymphoma

artículo científico publicado en 2008

The role of 18F-FDG-PET in detecting Richter's transformation of chronic lymphocytic leukemia in patients receiving therapy with a B-cell receptor inhibitor

scientific article published on 23 January 2020

The tumor suppressor axis p53/miR-34a regulates Axl expression in B-cell chronic lymphocytic leukemia: implications for therapy in p53-defective CLL patients

artículo científico publicado en 2013

The yin and yang of lenalidomide

artículo científico publicado en 2008

Treatment of autoimmune cytopenia complicating progressive chronic lymphocytic leukemia/small lymphocytic lymphoma with rituximab, cyclophosphamide, vincristine, and prednisone

artículo científico publicado en 2010

Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy

artículo científico publicado en 2020

Tris (dibenzylideneacetone) dipalladium: a small-molecule palladium complex is effective in inducing apoptosis in chronic lymphocytic leukemia B-cells

artículo científico publicado en 2016

Tumor mutational load predicts time to first treatment in chronic lymphocytic leukemia (CLL) and monoclonal B-cell lymphocytosis beyond the CLL international prognostic index

scientific article published on 12 April 2020

Update on monoclonal antibody therapy in chronic lymphocytic leukemia.

artículo científico publicado en 2004

Update on risk-stratified management for chronic lymphocytic leukemia

artículo científico publicado en 2006

Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection

artículo científico publicado en 2008

Using smudge cells on routine blood smears to predict clinical outcome in chronic lymphocytic leukemia: a universally available prognostic test

artículo científico publicado en 2007

VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2004

VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance

artículo científico publicado en 2005

Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia

artículo científico publicado en 2014

Validation of a new prognostic index for patients with chronic lymphocytic leukemia

scientific article published on January 2009

Vardenafil, a clinically available phosphodiesterase inhibitor, potentiates the killing effect of EGCG on CLL cells

artículo científico publicado en 2014

Vitamin D insufficiency and prognosis in chronic lymphocytic leukemia

artículo científico publicado en 2010

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

artículo científico publicado en 2004

ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype

artículo científico publicado en 2005

Zinc and T-lymphocyte function in hemodialysis patients

artículo científico publicado en 1982

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