Lista de obras - Simon Pearce - Dominio Público Uruguay

2013 ETA Guideline: Management of Subclinical Hypothyroidism

artículo científico publicado en 2013

2018 European Thyroid Association Guideline for the Management of Graves' Hyperthyroidism

artículo científico publicado en 2018

A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison's Disease in Humans

artículo científico publicado en 2016

A novel CLDN16 mutation in a large family with familial hypomagnesaemia with hypercalciuria and nephrocalcinosis

artículo científico publicado en 2013

AIRE is not essential for the induction of human tolerogenic dendritic cells

artículo científico publicado en 2016

Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects

artículo científico publicado en 2015

Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial

scientific article published on 21 January 2019

Adrenal insufficiency - recognition and management.

artículo científico publicado en 2017

Adrenal steroidogenesis after B lymphocyte depletion therapy in new-onset Addison's disease

artículo científico publicado en 2012

An ancient founder mutation in PROKR2 impairs human reproduction

artículo científico publicado en 2012

An unusual cause of adrenal insufficiency and bilateral adrenal masses.

artículo científico publicado en 2018

Analysis of BAFF gene polymorphisms in UK Graves' disease patients

article

Anti-neutrophil cytoplasmic antibody (ANCA) associated small-vessel vasculitis in a patient with diabetic nephropathy and autoimmune polyendocrinopathy syndrome (APS) Type 2: a case report.

artículo científico publicado en 2013

Antidepressant augmentation with metyrapone for treatment-resistant depression (the ADD study): a double-blind, randomised, placebo-controlled trial.

artículo científico publicado en 2015

Antigen-Specific Immunotherapy with Thyrotropin Receptor Peptides in Graves' Hyperthyroidism: A Phase I Study

artículo científico publicado en 2019

Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease

article

Attitudes and perceptions of health professionals towards management of hypothyroidism in general practice: a qualitative interview study

artículo científico publicado en 2018

Autoimmune Addison disease: pathophysiology and genetic complexity.

artículo científico

Autoimmune Addison's disease.

artículo científico publicado en 2012

CTLA-4 as a genetic determinant in autoimmune Addison's disease.

artículo científico publicado en 2015

Calcium-sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism

artículo científico publicado en 1995

Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders.

artículo científico publicado en 1997

Clinical review: The thyroid in mind: cognitive function and low thyrotropin in older people

artículo científico publicado en 2012

Clinical, behavioural and pharmacogenomic factors influencing the response to levothyroxine therapy in patients with primary hypothyroidism-protocol for a systematic review.

artículo científico publicado en 2017

Consensus statement of the European Group on Graves' orbitopathy (EUGOGO) on management of GO.

artículo científico publicado en 2008

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.

artículo científico

Current and emerging therapies for Addison's disease.

artículo científico publicado en 2014

Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism confers susceptibility to thyroid associated orbitopathy

artículo científico publicado en 1999

Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosis

article

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice

artículo científico publicado en 2008

Diagnosis and management of thyrotoxicosis

artículo científico publicado en 2014

Diagnosis and management of vitamin D deficiency.

artículo científico publicado en 2010

Diagnostic challenges due to phenocopies: lessons from Multiple Endocrine Neoplasia type1 (MEN1)

artículo científico publicado en 2010

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

artículo científico publicado en 2007

Discordance for X-linked hypophosphataemic rickets in identical twin girls

artículo científico publicado en 2009

Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells.

artículo científico publicado en 2003

Do antithyroid drugs influence outcome after radioiodine therapy for hyperthyroidism?

artículo científico publicado en 2007

Expanding the genotypic spectrum of Perrault syndrome.

artículo científico publicado en 2016

Expression of melanocortin receptors in human endometrium.

artículo científico publicado en 2015

Extracellular calcium‐sensing receptor dysfunction is associated with two new phenotypes ⬇️

artículo científico publicado el 1 de octubre de 2003

Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study

artículo científico publicado en 2010

Future Research in Graves' Orbitopathy: From Priority Setting to Trial Design Through Patient and Public Involvement

artículo científico publicado en 2015

Genetic progress towards the molecular basis of autoimmunity.

artículo científico publicado en 2006

Genetic progress towards the molecular basis of common autoimmunity

scientific article published on 1 February 2006

Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility.

artículo científico publicado en 2007

High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients

artículo científico publicado en 2014

How should we treat patients with low serum thyrotropin concentrations?

artículo científico publicado en 2009

Impact of Month of Birth on the Risk of Development of Autoimmune Addison's Disease

scientific article published on 30 August 2016

Impact of month of birth on the development of autoimmune thyroid disease in the United Kingdom and Europe

artículo científico publicado en 2014

Improving the prehospital safety of steroid-dependent patients in northern England: A hospital-initiated ambulance service registration pathway.

artículo científico publicado en 2017

In vivo and in vitro characterization of neonatal hyperparathyroidism resulting from a de novo, heterozygous mutation in the Ca2+-sensing receptor gene: normal maternal calcium homeostasis as a cause of secondary hyperparathyroidism in familial [...]

artículo científico publicado en 1997

Insufficient evidence to favour prednisolone over hydrocortisone in glucocorticoid replacement

artículo científico publicado en 2014

Isolation of a multipotent mesenchymal stem cell-like population from human adrenal cortex.

artículo científico publicado en 2018

Left ventricular apical ballooning (takotsubo cardiomyopathy) in thyrotoxicosis

artículo científico publicado en 2007

Levothyroxine treatment of subclinical hypothyroidism, fatal and nonfatal cardiovascular events, and mortality

scientific article published on 01 May 2012

Linkage Analysis in Autoimmune Addison's Disease: NFATC1 as a Potential Novel Susceptibility Locus.

artículo científico publicado en 2015

Loperamide-induced hypopituitarism

artículo científico publicado en 2016

Low-dose levothyroxine did not improve symptoms in asymptomatic older people with subclinical hypothyroidism

artículo científico publicado en 2018

MANAGEMENT OF ENDOCRINE DISEASE: Regenerative therapies in autoimmune Addison's disease

artículo científico publicado en 2016

Management of hypothyroidism in adults.

artículo científico publicado en 2008

Many men are receiving unnecessary testosterone prescriptions

artículo científico publicado en 2012

Medical therapy of macroprolactinomas in males: I. Prevalence of hypopituitarism at diagnosis. II. Proportion of cases exhibiting recovery of pituitary function

artículo científico publicado el 1 de enero de 2002

Mutational analysis of the adaptor protein 2 sigma subunit (AP2S1) gene: search for autosomal dominant hypocalcemia type 3 (ADH3).

artículo científico publicado en 2014

Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum.

artículo científico publicado en 2008

No association of the codon 55 methionine to valine polymorphism in the SUMO4 gene with Graves' disease.

artículo científico publicado en 2005

Older patients' experience of primary hypothyroidism: A qualitative study

artículo científico publicado en 2018

PREGO (presentation of Graves' orbitopathy) study: changes in referral patterns to European Group On Graves' Orbitopathy (EUGOGO) centres over the period from 2000 to 2012.

artículo científico publicado en 2015

Patient knowledge of antithyroid drug-induced agranulocytosis

artículo científico publicado en 2014

Patients' attitudes and perceptions towards treatment of hypothyroidism in general practice: an in-depth qualitative interview study

scientific article published on 28 June 2017

Phaeochromocytoma and acth-dependent cushing's syndrome: Tumor crf-secretion can mimic pituitary cushing's disease.

artículo científico publicado en 2015

Prevention and treatment of vitamin D deficiency.

artículo científico publicado en 2012

Primary hyperparathyroidism: just how 'primary' is it really?

artículo científico publicado en 2010

Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility

artículo científico publicado en 2009

Rapid onset childhood cataracts leading to the diagnosis of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

scientific article published on 01 November 2003

Reply on the Letter by Stott et al. 'The Dilemma of Treating Subclinical Hypothyroidism: Risk that Current Guidelines Do More Harm than Good'.

artículo científico publicado en 2014

Residual Adrenal Function in Autoimmune Addison's Disease-Effect of Dual Therapy With Rituximab and Depot Tetracosactide

artículo científico publicado en 2020

Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment.

artículo científico publicado en 2013

Rethinking antithyroid drugs in pregnancy.

artículo científico publicado en 2014

Reversal of idiopathic hypogonadotropic hypogonadism

article

Role of the CD40 locus in Graves' disease.

artículo científico publicado en 2004

Role of the X-Linked GeneGPR174in Autoimmune Addison's Disease

artículo científico publicado en 2015

Saving lives of in-patients with adrenal insufficiency: implementation of an alert scheme within the Newcastle-upon-Tyne Hospitals e-Prescribing platform.

artículo científico publicado en 2014

Serum 25-hydroxyvitamin D concentration and its determinants in the very old: the Newcastle 85+ Study.

artículo científico publicado en 2015

Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study ⬇️

artículo científico publicado en 2016

Spontaneous and tetracosactide-induced anti-ACTH antibodies in man.

artículo científico publicado en 2015

Study of Optimal Replacement of Thyroxine in the ElDerly (SORTED): protocol for a mixed methods feasibility study to assess the clinical utility of lower dose thyroxine in elderly hypothyroid patients: study protocol for a randomized controlled tria

artículo científico publicado en 2013

Study of Optimal Replacement of Thyroxine in the Elderly (SORTED) - results from the feasibility randomised controlled trial.

artículo científico publicado en 2016

Subclinical hyperthyroidism: first do no harm

artículo científico publicado en 2016

Subclinical hypothyroidism and cardiovascular disease-reply

artículo científico publicado en 2012

Subclinical thyroid disease: time to enter the age of evidence-based medicine

artículo científico publicado en 2012

Sun and melanoma: Time to go to get your hat

scientific article published on 06 August 2008

The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus.

artículo científico publicado en 1999

The deleted in colorectal carcinoma (DCC) gene 201 R --> G polymorphism: no evidence for genetic association with autoimmune disease.

artículo científico publicado en 2003

The genetics of autoimmune thyroid disease.

artículo científico publicado en 2002

The incidence of ischemic heart disease and mortality in people with subclinical hypothyroidism: reanalysis of the Whickham Survey cohort.

artículo científico publicado en 2010

The influence of age on the relationship between subclinical hypothyroidism and ischemic heart disease: a metaanalysis.

artículo científico publicado en 2008

The role of a nonsynonymous CD226 (DNAX-accessory molecule-1) variant (Gly 307Ser) in isolated Addison’s disease and autoimmune polyendocrinopathy type 2 pathogenesis

artículo científico publicado en 2011

The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease.

artículo científico publicado en 2008

Thyroid Hormone Therapy for Subclinical Hypothyroidism

artículo científico publicado en 2019

Thyroid hormones and cardiovascular disease

artículo científico publicado en 2016

Thyroxine in acute myocardial infarction (ThyrAMI) - levothyroxine in subclinical hypothyroidism post-acute myocardial infarction: study protocol for a randomised controlled trial.

artículo científico publicado en 2015

Toward precise forecasting of autoimmune endocrinopathy

artículo científico publicado en 2004

Treatment for primary hypothyroidism: current approaches and future possibilities ⬇️

artículo científico publicado el 22 de diciembre de 2011

Tremelimumab-Induced Graves Hyperthyroidism.

artículo científico

Trends in thyroid hormone prescribing and consumption in the UK

artículo científico publicado en 2009

Unrecognised severe vitamin D deficiency

artículo científico publicado en 2008

Ventriculitis from a pituitary prolactinoma: bacterial or chemical?

artículo científico publicado en 2016

Vitamin D testing

What is the evidence behind the evidence-base? The premature death of block-replace antithyroid drug regimens for Graves’ disease

artículo científico publicado en 2006

Lista de obras de Simon Pearce

2013 ETA Guideline: Management of Subclinical Hypothyroidism

2018 European Thyroid Association Guideline for the Management of Graves' Hyperthyroidism

A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison's Disease in Humans

A novel CLDN16 mutation in a large family with familial hypomagnesaemia with hypercalciuria and nephrocalcinosis

AIRE is not essential for the induction of human tolerogenic dendritic cells

Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects

Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial

Adrenal insufficiency - recognition and management.

Adrenal steroidogenesis after B lymphocyte depletion therapy in new-onset Addison's disease

An ancient founder mutation in PROKR2 impairs human reproduction

An unusual cause of adrenal insufficiency and bilateral adrenal masses.

Analysis of BAFF gene polymorphisms in UK Graves' disease patients

Anti-neutrophil cytoplasmic antibody (ANCA) associated small-vessel vasculitis in a patient with diabetic nephropathy and autoimmune polyendocrinopathy syndrome (APS) Type 2: a case report.

Antidepressant augmentation with metyrapone for treatment-resistant depression (the ADD study): a double-blind, randomised, placebo-controlled trial.

Antigen-Specific Immunotherapy with Thyrotropin Receptor Peptides in Graves' Hyperthyroidism: A Phase I Study

Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease

Attitudes and perceptions of health professionals towards management of hypothyroidism in general practice: a qualitative interview study

Autoimmune Addison disease: pathophysiology and genetic complexity.

Autoimmune Addison's disease.

CTLA-4 as a genetic determinant in autoimmune Addison's disease.

Calcium-sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism

Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders.

Clinical review: The thyroid in mind: cognitive function and low thyrotropin in older people

Clinical, behavioural and pharmacogenomic factors influencing the response to levothyroxine therapy in patients with primary hypothyroidism-protocol for a systematic review.

Consensus statement of the European Group on Graves' orbitopathy (EUGOGO) on management of GO.

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.

Current and emerging therapies for Addison's disease.

Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism confers susceptibility to thyroid associated orbitopathy

Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosis

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice

Diagnosis and management of thyrotoxicosis

Diagnosis and management of vitamin D deficiency.

Diagnostic challenges due to phenocopies: lessons from Multiple Endocrine Neoplasia type1 (MEN1)

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

Discordance for X-linked hypophosphataemic rickets in identical twin girls

Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells.

Do antithyroid drugs influence outcome after radioiodine therapy for hyperthyroidism?

Expanding the genotypic spectrum of Perrault syndrome.

Expression of melanocortin receptors in human endometrium.

Extracellular calcium‐sensing receptor dysfunction is associated with two new phenotypes ⬇️

Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study

Future Research in Graves' Orbitopathy: From Priority Setting to Trial Design Through Patient and Public Involvement

Genetic progress towards the molecular basis of autoimmunity.

Genetic progress towards the molecular basis of common autoimmunity

Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility.

High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients

How should we treat patients with low serum thyrotropin concentrations?

Impact of Month of Birth on the Risk of Development of Autoimmune Addison's Disease

Impact of month of birth on the development of autoimmune thyroid disease in the United Kingdom and Europe

Improving the prehospital safety of steroid-dependent patients in northern England: A hospital-initiated ambulance service registration pathway.

In vivo and in vitro characterization of neonatal hyperparathyroidism resulting from a de novo, heterozygous mutation in the Ca2+-sensing receptor gene: normal maternal calcium homeostasis as a cause of secondary hyperparathyroidism in familial [...]

Insufficient evidence to favour prednisolone over hydrocortisone in glucocorticoid replacement

Isolation of a multipotent mesenchymal stem cell-like population from human adrenal cortex.

Left ventricular apical ballooning (takotsubo cardiomyopathy) in thyrotoxicosis

Levothyroxine treatment of subclinical hypothyroidism, fatal and nonfatal cardiovascular events, and mortality

Linkage Analysis in Autoimmune Addison's Disease: NFATC1 as a Potential Novel Susceptibility Locus.

Loperamide-induced hypopituitarism

Low-dose levothyroxine did not improve symptoms in asymptomatic older people with subclinical hypothyroidism

MANAGEMENT OF ENDOCRINE DISEASE: Regenerative therapies in autoimmune Addison's disease

Management of hypothyroidism in adults.

Many men are receiving unnecessary testosterone prescriptions

Medical therapy of macroprolactinomas in males: I. Prevalence of hypopituitarism at diagnosis. II. Proportion of cases exhibiting recovery of pituitary function

Mutational analysis of the adaptor protein 2 sigma subunit (AP2S1) gene: search for autosomal dominant hypocalcemia type 3 (ADH3).

Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum.

No association of the codon 55 methionine to valine polymorphism in the SUMO4 gene with Graves' disease.

Older patients' experience of primary hypothyroidism: A qualitative study

PREGO (presentation of Graves' orbitopathy) study: changes in referral patterns to European Group On Graves' Orbitopathy (EUGOGO) centres over the period from 2000 to 2012.

Patient knowledge of antithyroid drug-induced agranulocytosis

Patients' attitudes and perceptions towards treatment of hypothyroidism in general practice: an in-depth qualitative interview study

Phaeochromocytoma and acth-dependent cushing's syndrome: Tumor crf-secretion can mimic pituitary cushing's disease.

Prevention and treatment of vitamin D deficiency.

Primary hyperparathyroidism: just how 'primary' is it really?

Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility

Rapid onset childhood cataracts leading to the diagnosis of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

Reply on the Letter by Stott et al. 'The Dilemma of Treating Subclinical Hypothyroidism: Risk that Current Guidelines Do More Harm than Good'.

Residual Adrenal Function in Autoimmune Addison's Disease-Effect of Dual Therapy With Rituximab and Depot Tetracosactide

Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment.

Rethinking antithyroid drugs in pregnancy.

Reversal of idiopathic hypogonadotropic hypogonadism