Lista de obras - Alessandro Doria - Dominio Público Uruguay

A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies

artículo científico publicado en 2019

A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians

scientific article published on 28 July 2004

A functional variant in the gene 3' untranslated region regulates HSP70 expression and is a potential candidate for insulin resistance-related abnormalities

artículo científico publicado en 2009

A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples

artículo científico publicado en 2008

A polymorphism at the IL6ST (gp130) locus is associated with traits of the metabolic syndrome.

artículo científico publicado en 2008

A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes.

artículo científico publicado en 2006

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

artículo científico publicado en 2013

Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.

artículo científico publicado en 2015

Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose

artículo científico publicado en 1995

Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes

artículo científico publicado en 2006

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene

article

Angiotensin I-converting enzyme (ACE): estimation of DNA haplotypes in unrelated individuals using denaturing gradient gel blots

scientific article published on 01 August 1994

Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes

artículo científico publicado en 1996

Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes

artículo científico publicado en 2013

Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects ⬇️

artículo científico publicado el 22 de agosto de 2013

Association of hGrb10 genetic variations with type 2 diabetes in Caucasian subjects.

artículo científico publicado en 2006

Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes.

artículo científico publicado en 2008

CTLA4-Ig in B7-1-positive diabetic and non-diabetic kidney disease

artículo científico

Can existing drugs approved for other indications retard renal function decline in patients with type 1 diabetes and nephropathy?

artículo científico publicado en 2012

Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes

artículo científico publicado en 2012

Circulating high molecular weight adiponectin isoform is heritable and shares a common genetic background with insulin resistance in nondiabetic White Caucasians from Italy: evidence from a family-based study

artículo científico publicado en 2009

Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study

scientific article published on 16 May 2007

Clustering of risk factors in hypertensive insulin-dependent diabetics with high sodium-lithium countertransport

artículo científico publicado en 1992

Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus

artículo científico publicado en 1996

Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes

artículo científico publicado en 2006

DdeI polymorphism in the AGTR1 gene

artículo científico publicado en 1994

Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene

scientific article published on 01 May 1996

Diabetes: Lowering serum uric acid levels to prevent kidney failure

article published in 2011

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

artículo científico publicado en 2015

Early progressive renal decline precedes the onset of microalbuminuria and its progression to macroalbuminuria.

artículo científico publicado en 2013

Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes

scientific article published on 01 November 2004

Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23.

artículo científico publicado en 2006

Exclusion of insulin receptor substrate 2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes

scientific article published on 01 March 1999

Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion.

artículo científico publicado en 2005

GRB10 gene and type 2 diabetes in Whites.

artículo científico publicado en 2009

Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial

artículo científico publicado en 2016

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

artículo científico publicado en 2018

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes

artículo científico publicado en 2015

Genetic Variants in CPA6 and PRPF31 are Associated with Variation in Response to Metformin in Individuals with Type 2 Diabetes.

artículo científico publicado en 2018

Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.

artículo científico publicado en 2017

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

artículo científico publicado en 2009

Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease.

artículo científico publicado en 2007

Genetic markers of increased susceptibility to diabetic nephropathy.

artículo científico publicado en 1998

Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24.

artículo científico publicado en 2003

Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I--converting enzyme gene

scientific article published on 01 May 1994

Genetic predisposition to dyslipidemia and type 2 diabetes risk in two prospective cohorts

artículo científico publicado en 2012

Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies

artículo científico publicado en 2011

Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels

scientific article published on 03 April 2006

Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians

scientific article published on 01 September 2002

Genetic variation at the adiponectin locus and risk of type 2 diabetes in women

artículo científico publicado en 2004

Genetics of Diabetes Complications ⬇️

artículo científico publicado el 1 de diciembre de 2010

Genetics of Diabetic Micro- and Macrovascular Complications

article

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes

artículo científico publicado en 2009

Genome-wide associations and metabolic disease: the big revolution

artículo científico publicado en 2008

Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects

scientific article published on 10 September 2008

Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes

artículo científico publicado en 2007

Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians.

artículo científico publicado en 2006

High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up

artículo científico publicado en 2010

IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants.

artículo científico publicado en 2009

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23

artículo científico publicado en 2004

Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease

artículo científico publicado en 2017

Increased prevalence of proliferative retinopathy in patients with type 1 diabetes who are deficient in glucose-6-phosphate dehydrogenase

artículo científico publicado en 2011

Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes

artículo científico publicado en 2015

Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

artículo científico publicado en 2017

Intensive Risk Factor Management and Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: The ACCORD Trial

artículo científico publicado en 2020

Joint effect of insulin signaling genes on all-cause mortality

artículo científico publicado en 2014

Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance

artículo científico publicado en 2012

Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis.

artículo científico publicado en 2013

Ketone bodies increase glomerular filtration rate in normal man and in patients with type 1 (insulin-dependent) diabetes mellitus

scientific article published on 01 April 1987

Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labelled with stable isotopes.

artículo científico publicado en 1990

Leveraging Genetics to Improve Cardiovascular Health in Diabetes: The 2018 Edwin Bierman Award Lecture

scientific article published on 01 March 2019

Lipoprotein compositional abnormalities in type 1 (insulin-dependent) diabetic patients

scientific article published on 01 January 1993

Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes

scientific article published on 04 March 2019

Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus

scientific journal article

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

artículo científico publicado en 2013

Metabolic control of kidney hemodynamics in normal and insulin-dependent diabetic subjects. Effects of acetoacetic, lactic, and acetic acids

scientific article published on 01 September 1987

Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD.

artículo científico publicado en 2017

Molecular characterization of a DDEI melting polymorphism at the angiotensin I-converting enzyme (ACE) locus

scientific article published on 01 January 1994

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.

artículo científico publicado en 2004

Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes.

artículo científico publicado en 2001

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction

artículo científico publicado en 2009

Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

artículo científico publicado en 1999

Myocardial metabolism in type 1 diabetic patients without coronary artery disease

scientific article published on 01 January 1991

PAX4 mutations in Thais with maturity onset diabetes of the young

artículo científico publicado en 2007

PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid

scientific article published on 23 January 2020

Phenotypic characteristics of early-onset autosomal-dominant type 2 diabetes unlinked to known maturity-onset diabetes of the young (MODY) genes.

artículo científico publicado en 1999

Porcine and human insulin absorption from subcutaneous tissues in normal and insulin-dependent diabetic subjects: a deconvolution-based approach

artículo científico publicado en 1988

Preventing Early Renal Loss in Diabetes (PERL) Study: A Randomized Double-Blinded Trial of Allopurinol-Rationale, Design, and Baseline Data

scientific article published on 11 June 2019

Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study.

artículo científico publicado en 2011

Putting the genes for type II diabetes on the map

artículo científico publicado en 2001

Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. ⬇️

artículo científico publicado en 2010

SerpinB1 Promotes Pancreatic β Cell Proliferation

artículo científico publicado en 2015

Serum Resistin, Cardiovascular Disease and All-Cause Mortality in Patients with Type 2 Diabetes ⬇️

artículo científico publicado el 3 de junio de 2013

Serum resistin and glomerular filtration rate in patients with type 2 diabetes

artículo científico publicado en 2015

Serum resistin and kidney function: a family-based study in non-diabetic, untreated individuals

artículo científico publicado en 2012

Synergistic effect of angiotensin II type 1 receptor genotype and poor glycaemic control on risk of nephropathy in IDDM

scientific article published on 01 November 1997

Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes

scientific article published on 01 February 2007

The +276 G/T single nucleotide polymorphism of the adiponectin gene is associated with coronary artery disease in type 2 diabetic patients

artículo científico publicado en 2004

The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men

artículo científico publicado en 2005

The 9p21 coronary artery disease locus and kidney dysfunction in patients with Type 2 diabetes mellitus.

artículo científico publicado en 2012

The ENPP1 Q121 variant predicts major cardiovascular events in high-risk individuals: evidence for interaction with obesity in diabetic patients

artículo científico publicado en 2011

The IRS1 G972R polymorphism and glomerular filtration rate in patients with type 2 diabetes of European ancestry.

artículo científico publicado en 2013

The K121Q Polymorphism of the ENPP1/PC-1 Gene Is Associated With Insulin Resistance/Atherogenic Phenotypes, Including Earlier Onset of Type 2 Diabetes and Myocardial Infarction

article

The SH2B1 obesity locus and abnormal glucose homeostasis: lack of evidence for association from a meta-analysis in individuals of European ancestry.

artículo científico publicado en 2013

The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells

artículo científico publicado en 2011

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

artículo científico publicado en 2008

The role of HSP70 on ENPP1 expression and insulin-receptor activation.

artículo científico publicado en 2008

The role of aldose reductase gene in the susceptibility to diabetic nephropathy in Type II (non-insulin-dependent) diabetes mellitus

scientific article published on 01 January 1999

The type 2 diabetes and insulin-resistance locus near IRS1 is a determinant of HDL cholesterol and triglycerides levels among diabetic subjects

artículo científico publicado en 2011

Type I insulin-dependent diabetic patients show an impaired renal hemodynamic response to protein intake

scientific article published on 01 January 1988

Uric Acid and Diabetic Nephropathy Risk.

artículo científico publicado en 2018

Uric acid and risk of diabetic kidney disease

artículo científico publicado en 2020

Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study

artículo científico publicado en 2013

Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol

artículo científico publicado en 2008

Variations in adiponectin receptor genes and susceptibility to type 2 diabetes in women: a tagging-single nucleotide polymorphism haplotype analysis

scientific article published on 06 April 2007

Identificación e importancia del tejido adiposo marrón en adultos

artículo científico publicado en 2009

Lista de obras de Alessandro Doria

A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies

A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians

A functional variant in the gene 3' untranslated region regulates HSP70 expression and is a potential candidate for insulin resistance-related abnormalities

A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples

A polymorphism at the IL6ST (gp130) locus is associated with traits of the metabolic syndrome.

A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes.

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.

Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose

Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene

Angiotensin I-converting enzyme (ACE): estimation of DNA haplotypes in unrelated individuals using denaturing gradient gel blots

Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes

Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes

Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects ⬇️

Association of hGrb10 genetic variations with type 2 diabetes in Caucasian subjects.

Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes.

CTLA4-Ig in B7-1-positive diabetic and non-diabetic kidney disease

Can existing drugs approved for other indications retard renal function decline in patients with type 1 diabetes and nephropathy?

Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes

Circulating high molecular weight adiponectin isoform is heritable and shares a common genetic background with insulin resistance in nondiabetic White Caucasians from Italy: evidence from a family-based study

Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study

Clustering of risk factors in hypertensive insulin-dependent diabetics with high sodium-lithium countertransport

Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus

Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes

DdeI polymorphism in the AGTR1 gene

Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene

Diabetes: Lowering serum uric acid levels to prevent kidney failure

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

Early progressive renal decline precedes the onset of microalbuminuria and its progression to macroalbuminuria.

Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes

Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23.

Exclusion of insulin receptor substrate 2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes

Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion.

GRB10 gene and type 2 diabetes in Whites.

Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes

Genetic Variants in CPA6 and PRPF31 are Associated with Variation in Response to Metformin in Individuals with Type 2 Diabetes.

Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease.

Genetic markers of increased susceptibility to diabetic nephropathy.

Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24.

Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I--converting enzyme gene

Genetic predisposition to dyslipidemia and type 2 diabetes risk in two prospective cohorts

Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies

Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels

Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians

Genetic variation at the adiponectin locus and risk of type 2 diabetes in women

Genetics of Diabetes Complications ⬇️

Genetics of Diabetic Micro- and Macrovascular Complications

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes

Genome-wide associations and metabolic disease: the big revolution

Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects

Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes

Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians.

High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up

IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants.

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23

Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease

Increased prevalence of proliferative retinopathy in patients with type 1 diabetes who are deficient in glucose-6-phosphate dehydrogenase

Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes

Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

Intensive Risk Factor Management and Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: The ACCORD Trial

Joint effect of insulin signaling genes on all-cause mortality

Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance

Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis.

Ketone bodies increase glomerular filtration rate in normal man and in patients with type 1 (insulin-dependent) diabetes mellitus

Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labelled with stable isotopes.

Leveraging Genetics to Improve Cardiovascular Health in Diabetes: The 2018 Edwin Bierman Award Lecture

Lipoprotein compositional abnormalities in type 1 (insulin-dependent) diabetic patients

Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes

Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

Metabolic control of kidney hemodynamics in normal and insulin-dependent diabetic subjects. Effects of acetoacetic, lactic, and acetic acids

Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD.

Molecular characterization of a DDEI melting polymorphism at the angiotensin I-converting enzyme (ACE) locus

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.