Lista de obras - Keiryn L Bennett - Dominio Público Uruguay

13 Functional Proteomics of Innate Immunity Signalling

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.

artículo científico publicado en 2016

A Comprehensive Analytical Strategy To Identify Malondialdehyde-Modified Proteins and Peptides.

artículo científico publicado en 2017

A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

artículo científico publicado en 2015

A Surface Biotinylation Strategy for Reproducible Plasma Membrane Protein Purification and Tracking of Genetic and Drug-Induced Alterations.

artículo científico publicado en 2015

A Web Resource for Improved Analysis of AP-MS Protein Interaction Data

artículo científico publicado en 2013

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

artículo científico publicado en 2010

A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor

artículo científico publicado en 2017

A comparative proteomic study of human skin suction blister fluid from healthy individuals using immunodepletion and iTRAQ labeling

artículo científico publicado en 2012

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies

artículo científico publicado en 2013

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

artículo científico publicado en 2010

A reversible gene trap collection empowers haploid genetics in human cells

artículo científico publicado en 2013

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL

artículo científico publicado en 2013

A time-resolved molecular map of the macrophage response to VSV infection

artículo científico publicado en 2016

Affinity purification strategies for proteomic analysis of transcription factor complexes.

artículo científico publicado en 2013

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

artículo científico publicado en 2006

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

artículo científico publicado en 2011

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

artículo científico publicado en 2009

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

artículo científico publicado en 2016

CD14 is a coreceptor of Toll-like receptors 7 and 9. ⬇️

artículo científico publicado en 2010

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

artículo científico publicado en 2014

Cdk6 contributes to cytoskeletal stability in erythroid cells.

artículo científico publicado en 2017

Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein

artículo científico publicado en 2017

Charting the molecular network of the drug target Bcr-Abl

artículo científico publicado en 2009

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

scientific article published on 24 August 2007

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration

artículo científico publicado en 2015

Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities

artículo científico publicado en 2016

Complement Activation in Peritoneal Dialysis-Induced Arteriolopathy.

artículo científico publicado en 2017

Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma

artículo científico

Effects of alanyl-glutamine treatment on the peritoneal dialysis effluent proteome reveal pathomechanism-associated molecular signatures.

artículo científico publicado en 2017

Expanding the Interactome of the Noncanonical NF-κB Signaling Pathway

artículo científico publicado en 2016

Experimental Peptide Identification Repository (EPIR): an integrated peptide-centric platform for validation and mining of tandem mass spectrometry data

artículo científico publicado en 2004

Experimental characterization of the human non-sequence-specific nucleic acid interactome

artículo científico publicado en 2013

FASIL-MS: An Integrated Proteomic and Bioinformatic Workflow To Universally Quantitate In Vivo-Acetylated Positional Isomers.

artículo científico publicado en 2016

Functional dissection of the TBK1 molecular network

artículo científico publicado en 2011

Gene essentiality and synthetic lethality in haploid human cells

scientific journal article

General statistical modeling of data from protein relative expression isobaric tags.

artículo científico publicado en 2011

Germline RBBP6 mutations in familial myeloproliferative neoplasms.

artículo científico publicado en 2015

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

artículo científico publicado en 2016

Human Proteinpedia enables sharing of human protein data

artículo científico publicado en 2008

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

artículo científico publicado en 2011

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics

artículo científico publicado en 2014

Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry.

artículo científico publicado en 2016

Initial characterization of the human central proteome

artículo científico publicado en 2011

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

artículo científico publicado en 2013

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

artículo científico publicado en 2013

Introduction to computational proteomics

artículo científico publicado en 2007

JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia

artículo científico publicado en 2014

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.

artículo científico publicado en 2017

MASPECTRAS 2: An integration and analysis platform for proteomic data.

artículo científico publicado en 2010

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

artículo científico publicado en 2018

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation

artículo científico publicado en 2019

Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice

artículo científico publicado en 2016

Mass spectrometric analysis of synaptosomal membrane preparations for the determination of brain receptors, transporters and channels

artículo científico publicado en 2016

Multiple and sequential data acquisition method: an improved method for fragmentation and detection of cross-linked peptides on a hybrid linear trap quadrupole Orbitrap Velos mass spectrometer.

artículo científico publicado en 2013

Peptide end sequencing by orthogonal MALDI tandem mass spectrometry

artículo científico publicado en 2002

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

artículo científico publicado en 2013

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

artículo científico publicado en 2015

Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.

artículo científico publicado en 2002

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.

artículo científico publicado en 2015

Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ®-labelled specimens.

artículo científico

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.

artículo científico publicado en 2016

RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme

artículo científico publicado en 2008

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations

artículo científico publicado en 2012

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

artículo científico publicado en 2015

Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometry

artículo científico publicado en 2003

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

artículo científico publicado en 2014

Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae

artículo científico publicado en 2002

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

artículo científico publicado en 2002

Systems biology analysis of protein-drug interactions.

artículo científico publicado en 2011

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

artículo científico publicado en 2012

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

artículo científico publicado en 2015

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action† †Electronic supplementary information (ESI) available: Experimental, crystallographic, biological and mass spectrometric data, full list of pr

artículo científico publicado en 2015

Targeting a cell state common to triple-negative breast cancers

artículo científico publicado en 2015

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

artículo científico publicado en 2007

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

artículo científico publicado en 2013

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

artículo científico publicado en 2008

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

scientific journal article

The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity

artículo científico publicado en 2018

The RNA-binding protein HuR/ELAVL1 regulates IFN-β mRNA abundance and the type I IFN response

artículo científico publicado en 2015

Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders.

artículo científico publicado en 2018

Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer.

artículo científico publicado en 2010

Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity

scientific journal article

Viral immune modulators perturb the human molecular network by common and unique strategies

artículo científico publicado en 2012

Lista de obras de Keiryn L Bennett

13 Functional Proteomics of Innate Immunity Signalling

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.

A Comprehensive Analytical Strategy To Identify Malondialdehyde-Modified Proteins and Peptides.

A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

A Surface Biotinylation Strategy for Reproducible Plasma Membrane Protein Purification and Tracking of Genetic and Drug-Induced Alterations.

A Web Resource for Improved Analysis of AP-MS Protein Interaction Data

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor

A comparative proteomic study of human skin suction blister fluid from healthy individuals using immunodepletion and iTRAQ labeling

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

A reversible gene trap collection empowers haploid genetics in human cells

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL

A time-resolved molecular map of the macrophage response to VSV infection

Affinity purification strategies for proteomic analysis of transcription factor complexes.

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

CD14 is a coreceptor of Toll-like receptors 7 and 9. ⬇️

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

Cdk6 contributes to cytoskeletal stability in erythroid cells.

Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein

Charting the molecular network of the drug target Bcr-Abl

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration

Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities

Complement Activation in Peritoneal Dialysis-Induced Arteriolopathy.

Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma

Effects of alanyl-glutamine treatment on the peritoneal dialysis effluent proteome reveal pathomechanism-associated molecular signatures.

Expanding the Interactome of the Noncanonical NF-κB Signaling Pathway

Experimental Peptide Identification Repository (EPIR): an integrated peptide-centric platform for validation and mining of tandem mass spectrometry data

Experimental characterization of the human non-sequence-specific nucleic acid interactome

FASIL-MS: An Integrated Proteomic and Bioinformatic Workflow To Universally Quantitate In Vivo-Acetylated Positional Isomers.

Functional dissection of the TBK1 molecular network

Gene essentiality and synthetic lethality in haploid human cells

General statistical modeling of data from protein relative expression isobaric tags.

Germline RBBP6 mutations in familial myeloproliferative neoplasms.

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

Human Proteinpedia enables sharing of human protein data

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics

Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry.

Initial characterization of the human central proteome

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

Introduction to computational proteomics

JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.

MASPECTRAS 2: An integration and analysis platform for proteomic data.

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation

Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice

Mass spectrometric analysis of synaptosomal membrane preparations for the determination of brain receptors, transporters and channels

Multiple and sequential data acquisition method: an improved method for fragmentation and detection of cross-linked peptides on a hybrid linear trap quadrupole Orbitrap Velos mass spectrometer.

Peptide end sequencing by orthogonal MALDI tandem mass spectrometry

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.

Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ®-labelled specimens.

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.

RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometry

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

Systems biology analysis of protein-drug interactions.

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action† †Electronic supplementary information (ESI) available: Experimental, crystallographic, biological and mass spectrometric data, full list of pr

Targeting a cell state common to triple-negative breast cancers

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease