Lista de obras - Fiona Marshall - Dominio Público Uruguay

A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor

artículo científico publicado en 1997

A summary and conclusions from the meeting.

artículo científico publicado en 2005

Advances in the molecular understanding of GABA(B) receptors.

artículo científico publicado en 2001

Atomoxetine produces changes in cortico-basal thalamic loop circuits: assessed by phMRI BOLD contrast.

artículo científico publicado en 2006

Biacore analysis with stabilized G-protein-coupled receptors

artículo científico publicado en 2010

Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design

artículo científico publicado en 2013

Biophysical mapping of the adenosine A2A receptor

artículo científico publicado en 2011

Calcium sensing properties of the GABA(B) receptor.

artículo científico publicado en 1999

Cellular and sub-cellular localisation of GABA(B1) and GABA(B2) receptor proteins in the rat cerebellum

artículo científico publicado en 2000

Characterization of [3H]‐prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus ⬇️

artículo científico publicado el 1 de agosto de 1997

Cholecystokinin/dopamine interactions in the rat basal ganglia

Ph.D. dissertation

Conformational thermostabilisation of corticotropin releasing factor receptor 1.

artículo científico publicado en 2015

Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength

artículo científico publicado en 2016

Development of tolerance in mice to the sedative effects of the neuroactive steroid minaxolone following chronic exposure.

artículo científico publicado en 1997

Differential effects of the D- and L- isomers of amphetamine on pharmacological MRI BOLD contrast in the rat.

artículo científico publicado en 2007

Digestive physiology of the pig symposium: gut chemosensing and the regulation of nutrient absorption and energy supply

artículo científico publicado en 2013

Effects of amphetamine isomers, methylphenidate and atomoxetine on synaptosomal and synaptic vesicle accumulation and release of dopamine and noradrenaline in vitro in the rat brain

artículo científico publicado en 2006

Extra-helical binding site of a glucagon receptor antagonist

artículo científico publicado en 2016

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile)

artículo científico publicado en 2015

Fragment screening of GPCRs using biophysical methods: identification of ligands of the adenosine A(2A) receptor with novel biological activity

artículo científico publicado en 2012

From G Protein-coupled Receptor Structure Resolution to Rational Drug Design.

artículo científico publicado en 2015

G16 as a universal G protein adapter: implications for agonist screening strategies.

artículo científico publicado en 1996

GABA(B) receptor heterodimer-component localisation in human brain.

artículo científico publicado en 2000

GABAB receptor subunits, R1 and R2, in brainstem catecholamine and serotonin neurons.

artículo científico publicado en 2003

GABAB receptors - the first 7TM heterodimers.

artículo científico publicado en 1999

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

artículo científico publicado en 2015

Heterodimerization is required for the formation of a functional GABA(B) receptor

artículo científico publicado en 1998

Heterodimerization of G-protein-coupled receptors in the CNS.

artículo científico publicado en 2001

Heterodimerization of gamma-aminobutyric acid B receptor subunits as revealed by the yeast two-hybrid system.

artículo científico publicado en 2002

Identification of novel adenosine A(2A) receptor antagonists by virtual screening.

artículo científico publicado en 2012

Implications of metabotropic glutamate receptor structures for drug discovery in neurotherapeutics

scientific article published on 12 January 2015

Insights into the structure of class B GPCRs

artículo científico publicado en 2013

International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function

artículo científico publicado en 2002

Molecular identification of high and low affinity receptors for nicotinic acid

artículo científico publicado en 2003

Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment

scientific article published on January 2014

NOBEL 2012 Chemistry: Studies of a ubiquitous receptor family

artículo científico publicado en 2012

New insights from structural biology into the druggability of G protein-coupled receptors.

artículo científico publicado en 2012

Pharmacological profile of GR117289 in vitro: a novel, potent and specific non-peptide angiotensin AT1 receptor antagonist ⬇️

artículo científico publicado el 1 de diciembre de 1992

Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy

artículo científico publicado en 2013

Preparation of purified GPCRs for structural studies

artículo científico publicado en 2013

Purification of Stabilized GPCRs for Structural and Biophysical Analyses.

artículo científico publicado en 2015

Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants

artículo científico publicado en 2015

Structure of Class B GPCRs: new horizons for drug discovery

artículo científico

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

artículo científico publicado en 2014

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

artículo científico publicado en 2011

Structure-based drug design for G protein-coupled receptors.

artículo científico

Structures of G protein-coupled receptors reveal new opportunities for drug discovery.

artículo científico

Temperature and agonist dependency of tachykinin NK1 receptor antagonist potencies in rat isolated superior cervical ganglion.

artículo científico publicado en 1995

The impact of GPCR structures on pharmacology and structure-based drug design

artículo científico publicado en 2010

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery.

artículo científico publicado en 2010

The use of GPCR structures in drug design.

artículo científico

Therapeutic antibodies directed at G protein-coupled receptors

artículo científico publicado en 2010

Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.

artículo científico publicado en 2018

Lista de obras de Fiona Marshall

A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor

A summary and conclusions from the meeting.

Advances in the molecular understanding of GABA(B) receptors.

Atomoxetine produces changes in cortico-basal thalamic loop circuits: assessed by phMRI BOLD contrast.

Biacore analysis with stabilized G-protein-coupled receptors

Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design

Biophysical mapping of the adenosine A2A receptor

Calcium sensing properties of the GABA(B) receptor.

Cellular and sub-cellular localisation of GABA(B1) and GABA(B2) receptor proteins in the rat cerebellum

Characterization of [3H]‐prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus ⬇️

Cholecystokinin/dopamine interactions in the rat basal ganglia

Conformational thermostabilisation of corticotropin releasing factor receptor 1.

Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength

Development of tolerance in mice to the sedative effects of the neuroactive steroid minaxolone following chronic exposure.

Differential effects of the D- and L- isomers of amphetamine on pharmacological MRI BOLD contrast in the rat.

Digestive physiology of the pig symposium: gut chemosensing and the regulation of nutrient absorption and energy supply

Effects of amphetamine isomers, methylphenidate and atomoxetine on synaptosomal and synaptic vesicle accumulation and release of dopamine and noradrenaline in vitro in the rat brain

Extra-helical binding site of a glucagon receptor antagonist

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile)

Fragment screening of GPCRs using biophysical methods: identification of ligands of the adenosine A(2A) receptor with novel biological activity

From G Protein-coupled Receptor Structure Resolution to Rational Drug Design.

G16 as a universal G protein adapter: implications for agonist screening strategies.

GABA(B) receptor heterodimer-component localisation in human brain.

GABAB receptor subunits, R1 and R2, in brainstem catecholamine and serotonin neurons.

GABAB receptors - the first 7TM heterodimers.

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

Heterodimerization is required for the formation of a functional GABA(B) receptor

Heterodimerization of G-protein-coupled receptors in the CNS.

Heterodimerization of gamma-aminobutyric acid B receptor subunits as revealed by the yeast two-hybrid system.

Identification of novel adenosine A(2A) receptor antagonists by virtual screening.

Implications of metabotropic glutamate receptor structures for drug discovery in neurotherapeutics

Insights into the structure of class B GPCRs

International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function

Molecular identification of high and low affinity receptors for nicotinic acid

Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment

NOBEL 2012 Chemistry: Studies of a ubiquitous receptor family

New insights from structural biology into the druggability of G protein-coupled receptors.

Pharmacological profile of GR117289 in vitro: a novel, potent and specific non-peptide angiotensin AT1 receptor antagonist ⬇️

Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy

Preparation of purified GPCRs for structural studies

Purification of Stabilized GPCRs for Structural and Biophysical Analyses.

Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants

Structure of Class B GPCRs: new horizons for drug discovery

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

Structure-based drug design for G protein-coupled receptors.

Structures of G protein-coupled receptors reveal new opportunities for drug discovery.

Temperature and agonist dependency of tachykinin NK1 receptor antagonist potencies in rat isolated superior cervical ganglion.

The impact of GPCR structures on pharmacology and structure-based drug design

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery.

The use of GPCR structures in drug design.

Therapeutic antibodies directed at G protein-coupled receptors

Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.