Lista de obras - Eric Sorscher - Dominio Público Uruguay

8-cyclopentyl-1,3-dipropylxanthine and other xanthines differentially bind to the wild-type and delta F508 first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator

artículo científico publicado en 1997

A Comparison between Two Pathophysiologically Different yet Microbiologically Similar Lung Diseases: Cystic Fibrosis and Chronic Obstructive Pulmonary Disease

scholarly article by Daniel E Fenker et al published 2018 in International journal of respiratory and pulmonary medicine

A breath of fresh air

artículo científico publicado en 2011

A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis

artículo científico publicado en 2001

A functional anatomic defect of the cystic fibrosis airway

artículo científico publicado en 2014

A long-acting suicide gene toxin, 6-methylpurine, inhibits slow growing tumors after a single administration

artículo científico publicado en 2003

A macromolecular complex of beta 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA

artículo científico publicado en 2002

A method for the rapid detection of recombinant CFTR during gene therapy in cystic fibrosis.

artículo científico publicado en 1996

A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease

artículo científico publicado en 2012

A truncated CFTR protein rescues endogenous DeltaF508-CFTR and corrects chloride transport in mice

artículo científico publicado en 2009

A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis.

artículo científico publicado en 2012

A2 adenosine receptors regulate CFTR through PKA and PLA2 ⬇️

artículo científico publicado el 1 de enero de 2002

Ablation of internalization signals in the carboxyl-terminal tail of the cystic fibrosis transmembrane conductance regulator enhances cell surface expression

artículo científico publicado en 2002

Activation of airway cl- secretion in human subjects by adenosine.

artículo científico publicado en 2004

Activation of chloride secretion in cystic fibrosis cells and tissues by the substituted imidazole SRI 2931.

artículo científico publicado en 2003

Activation of ΔF508 CFTR in an epithelial monolayer ⬇️

artículo científico publicado el 1 de agosto de 1998

Adenosine receptors and phosphodiesterase inhibitors stimulate Cl- secretion in Calu-3 cells

artículo científico publicado en 2003

Adenoviral gene delivery elicits distinct pulmonary-associated T helper cell responses to the vector and to its transgene ⬇️

artículo científico publicado el 15 de julio de 1997

Affinity purification of insoluble recombinant fusion proteins containing glutathione-S-transferase.

artículo científico publicado en 1992

Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.

artículo científico publicado en 2002

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

artículo científico publicado en 2019

An autoregulatory mechanism governing mucociliary transport is sensitive to mucus load

artículo científico publicado en 2014

Analysis of cystic fibrosis-associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases

artículo científico publicado en 2016

Antibodies against purified epithelial sodium channel protein from bovine renal papilla

artículo científico publicado en 1988

Antisense oligodeoxynucleotide to the cystic fibrosis gene inhibits anion transport in normal cultured sweat duct cells

artículo científico publicado en 1991

Assessing cell-specific effects of genetic variations using tRNA microarrays

scientific article published on 16 July 2019

Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing.

artículo científico publicado en 2004

Association of cystic fibrosis genetic modifiers with congenital bilateral absence of the vas deferens

artículo científico publicado en 2010

Bioelectric effects of quinine on polarized airway epithelial cells

artículo científico publicado en 2007

Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene.

artículo científico publicado en 1995

CFTR Folding Consortium: methods available for studies of CFTR folding and correction

artículo científico publicado en 2011

CFTR modulator theratyping: Current status, gaps and future directions

artículo científico publicado en 2018

Cell to Cell Contact Is Not Required for Bystander Cell Killing by Escherichia coli Purine Nucleoside Phosphorylase ⬇️

artículo científico publicado el 23 de enero de 1998

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

artículo científico publicado en 2015

Characterization of defects in ion transport and tissue development in cystic fibrosis transmembrane conductance regulator (CFTR)-knockout rats

artículo científico publicado en 2014

Chlorogenic Acid Activates CFTR-Mediated Cl- Secretion in Mice and Humans: Therapeutic Implications for Chronic Rhinosinusitis.

artículo científico publicado en 2015

Chlorzoxazone or 1-EBIO increases Na(+) absorption across cystic fibrosis airway epithelial cells

artículo científico publicado en 2001

Cigarette smoke condensate inhibits transepithelial chloride transport and ciliary beat frequency

artículo científico publicado en 2009

Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model

scientific article published on 16 March 2006

Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy

artículo científico publicado en 2016

Comparison of cystic fibrosis transmembrane conductance regulator (CFTR) and ciliary beat frequency activation by the CFTR Modulators Genistein, VRT-532, and UCCF-152 in primary sinonasal epithelial cultures

artículo científico publicado en 2013

Comparison of vectorial ion transport in primary murine airway and human sinonasal air-liquid interface cultures, models for studies of cystic fibrosis, and other airway diseases.

artículo científico publicado en 2009

Correction: Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung Disease

artículo científico publicado en 2013

Correction: Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability

artículo científico publicado en 2014

Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis

artículo científico publicado en 2009

Cystic fibrosis

artículo científico publicado en 2005

Cystic fibrosis precision therapeutics: Emerging considerations

scientific article published on 01 November 2019

Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain 1 (NBD-1) and CFTR truncated within NBD-1 target to the epithelial plasma membrane and increase anion permeability

artículo científico publicado en 1998

Cystic fibrosis transmembrane conductance regulator activation by the solvent ethanol: implications for topical drug delivery.

artículo científico publicado en 2015

Cystic fibrosis transmembrane conductance regulator modulation by the tobacco smoke toxin acrolein

artículo científico publicado en 2012

Cystic fibrosis transmembrane conductance regulator mutations that disrupt nucleotide binding

artículo científico publicado en 1994

Cystic fibrosis: a disorder of calcium-stimulated secretion and transepithelial sodium transport?

scientific article published on 01 February 1982

Development of an airway mucus defect in the cystic fibrosis rat.

artículo científico publicado en 2018

Development of drug targeting based on recombinant expression of the chicken avidin gene

artículo científico publicado en 1996

Diagnosis of genetic disease by primer-specified restriction map modification, with application to cystic fibrosis and retinitis pigmentosa

artículo científico publicado en 1991

Effects of megestrol acetate on weight gain, body composition, and pulmonary function in patients with cystic fibrosis

artículo científico publicado en 2002

Efficiency of plasmid delivery and expression after lipid-mediated gene transfer to human cells in vitro

artículo científico publicado en 1996

Efficient intracellular processing of the endogenous cystic fibrosis transmembrane conductance regulator in epithelial cell lines

artículo científico publicado en 2004

Elevation of hepatic sulphotransferase activities in mice with resistance to cystic fibrosis.

artículo científico publicado en 2002

Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones

artículo científico publicado en 2008

Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis

artículo científico publicado en 2001

Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene

artículo científico publicado en 2004

Exposure to cigarette smoke condensate reduces calcium activated chloride channel transport in primary sinonasal epithelial cultures

artículo científico publicado en 2010

Extracellular zinc and ATP restore chloride secretion across cystic fibrosis airway epithelia by triggering calcium entry

artículo científico publicado en 2003

Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers

artículo científico publicado en 2005

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

artículo científico publicado en 2016

Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report

artículo científico publicado en 2012

Gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway

artículo científico publicado en 1994

Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase

artículo científico publicado en 1999

Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues

scientific article published on 22 May 2020

Hesperidin stimulates cystic fibrosis transmembrane conductance regulator-mediated chloride secretion and ciliary beat frequency in sinonasal epithelium

artículo científico publicado en 2010

Heterozygosity for the F508del mutation in the cystic fibrosis transmembrane conductance regulator anion channel attenuates influenza severity

artículo científico publicado en 2013

Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction

scientific article published on 29 April 2020

Identification of a membrane protein from T84 cells using antibodies made against a DIDS-binding peptide

artículo científico publicado en 1992

Immunochemical localization of amiloride-sensitive sodium channels in sodium-transporting epithelia

artículo científico publicado en 1989

In VivoGene Therapy of Cancer withE. coliPurine Nucleoside Phosphorylase ⬇️

artículo científico publicado el 20 de septiembre de 1997

In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells

artículo científico publicado en 2000

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics

artículo científico publicado en 2016

Informed consent to participate in a research study -- gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway

article

Inhibitory effects of hypertonic saline on P. aeruginosa motility

artículo científico publicado en 2008

Interaction between cystic fibrosis transmembrane conductance regulator and outwardly rectified chloride channels

artículo científico publicado en 1995

Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools.

artículo científico publicado en 2014

Interregulation of proton-gated Na(+) channel 3 and cystic fibrosis transmembrane conductance regulator

artículo científico publicado en 2006

Intrinsic anion channel activity of the recombinant first nucleotide binding fold domain of the cystic fibrosis transmembrane regulator protein

artículo científico publicado en 1992

Ivacaftor Reverses Airway Mucus Abnormalities in a Rat Model Harboring a Humanized G551D-CFTR

artículo científico publicado en 2020

Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus

artículo científico publicado en 2005

Longevity and plasticity of CFTR provide an argument for noncanonical SNP organization in hominid DNA

artículo científico publicado en 2014

Making precision medicine personal for cystic fibrosis

scientific article published on 01 July 2019

Marked repression of CFTR mRNA in the transgenic Cftr(tm1kth) mouse model

artículo científico publicado en 2013

Massive microRNA sequence conservation and prevalence in human and chimpanzee introns

artículo científico publicado el 1 de junio de 2013

Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography

artículo científico publicado en 2013

Micro-RNA-like effects of complete intronic sequences

artículo científico publicado en 2006

Molecular proximity of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel assessed by fluorescence resonance energy transfer

artículo científico publicado en 2007

Mutations in the amino terminus of the cystic fibrosis transmembrane conductance regulator enhance endocytosis

artículo científico publicado en 2005

Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease

artículo científico publicado en 2013

Non-obstructive vas deferens and epididymis loss in cystic fibrosis rats

artículo científico publicado en 2018

One-step affinity isolation of recombinant protein using the baculovirus/insect cell expression system

artículo científico publicado en 1993

Porcine nasal epithelial cultures for studies of cystic fibrosis sinusitis

artículo científico publicado en 2014

Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity

artículo científico publicado en 2021

Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

artículo científico publicado en 2008

Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications

artículo científico publicado en 2011

Purification, characterization, and expression of CFTR nucleotide-binding domains ⬇️

artículo científico publicado el 1 de octubre de 1997

Quercetin increases cystic fibrosis transmembrane conductance regulator-mediated chloride transport and ciliary beat frequency: therapeutic implications for chronic rhinosinusitis

artículo científico publicado en 2011

Rapid purification of recombinant baculovirus using fluorescence-activated cell sorting

artículo científico publicado en 1993

Reactive oxygen nitrogen species decrease cystic fibrosis transmembrane conductance regulator expression and cAMP-mediated Cl- secretion in airway epithelia

artículo científico publicado en 2002

Recombinant synthesis of cystic fibrosis transmembrane conductance regulator and functional nucleotide-binding domains

artículo científico publicado en 1998

Recombinant synthesis, purification, and nucleotide binding characteristics of the first nucleotide binding domain of the cystic fibrosis gene product ⬇️

artículo científico publicado el 5 de abril de 1992

Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat.

artículo científico publicado en 2017

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

artículo científico publicado en 2010

Regulation of plasma membrane recycling by CFTR.

artículo científico publicado en 1992

Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators

artículo científico publicado en 2011

Relationship between airway ion transport and a mild pulmonary disease mutation in CFTR.

artículo científico publicado en 1997

Residual function of cystic fibrosis mutants predicts response to small molecule CFTR modulators

scientific article published on 26 July 2018

Respiratory syncytial virus infection disrupts monolayer integrity and function in cystic fibrosis airway cells

artículo científico publicado en 2013

Restoration of W1282X CFTR activity by enhanced expression

artículo científico publicado en 2007

Resveratrol enhances airway surface liquid depth in sinonasal epithelium by increasing cystic fibrosis transmembrane conductance regulator open probability

artículo científico publicado en 2013

Resveratrol has salutary effects on mucociliary transport and inflammation in sinonasal epithelium

artículo científico publicado en 2011

Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect

artículo científico publicado en 2016

Robust Stimulation of W1282X-CFTR Channel Activity by a Combination of Allosteric Modulators

artículo científico publicado en 2016

Role for phospholipid interactions in the trafficking defect of Delta F508-CFTR.

artículo científico publicado en 2002

Role of oxygen availability in CFTR expression and function

artículo científico publicado en 2008

S-palmitoylation regulates biogenesis of core glycosylated wild-type and F508del CFTR in a post-ER compartment

scientific article published on April 2014

SNP Formation Bias in the Murine Genome Provides Evidence for Parallel Evolution

artículo científico publicado en 2015

Severe phenotype in mice with termination mutation in exon 2 of cystic fibrosis gene

artículo científico publicado en 1995

Sinupret activates CFTR and TMEM16A-dependent transepithelial chloride transport and improves indicators of mucociliary clearance

artículo científico publicado en 2014

Slowing ribosome velocity restores folding and function of mutant CFTR

scientific article published on 01 December 2019

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line

artículo científico publicado en 1997

Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells.

artículo científico publicado en 2015

The bioflavonoid compound, sinupret, stimulates transepithelial chloride transport in vitro and in vivo

artículo científico publicado en 2010

The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary

artículo científico publicado en 1998

The silent codon change I507-ATC->ATT contributes to the severity of the ΔF508 CFTR channel dysfunction

artículo científico publicado en 2013

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors

artículo científico publicado en 2020

Trafficking and function of the cystic fibrosis transmembrane conductance regulator: a complex network of posttranslational modifications

artículo científico publicado en 2016

Transepithelial ion transport is suppressed in hypoxic sinonasal epithelium

artículo científico publicado en 2011

Transformative therapies for rare CFTR missense alleles

artículo científico publicado en 2017

Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines

artículo científico publicado el 1 de julio de 1994

VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level

artículo científico publicado en 2019

Lista de obras de Eric Sorscher

8-cyclopentyl-1,3-dipropylxanthine and other xanthines differentially bind to the wild-type and delta F508 first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator

A Comparison between Two Pathophysiologically Different yet Microbiologically Similar Lung Diseases: Cystic Fibrosis and Chronic Obstructive Pulmonary Disease

A breath of fresh air

A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis

A functional anatomic defect of the cystic fibrosis airway

A long-acting suicide gene toxin, 6-methylpurine, inhibits slow growing tumors after a single administration

A macromolecular complex of beta 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA

A method for the rapid detection of recombinant CFTR during gene therapy in cystic fibrosis.

A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease

A truncated CFTR protein rescues endogenous DeltaF508-CFTR and corrects chloride transport in mice

A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis.

A2 adenosine receptors regulate CFTR through PKA and PLA2 ⬇️

Ablation of internalization signals in the carboxyl-terminal tail of the cystic fibrosis transmembrane conductance regulator enhances cell surface expression

Activation of airway cl- secretion in human subjects by adenosine.

Activation of chloride secretion in cystic fibrosis cells and tissues by the substituted imidazole SRI 2931.

Activation of ΔF508 CFTR in an epithelial monolayer ⬇️

Adenosine receptors and phosphodiesterase inhibitors stimulate Cl- secretion in Calu-3 cells

Adenoviral gene delivery elicits distinct pulmonary-associated T helper cell responses to the vector and to its transgene ⬇️

Affinity purification of insoluble recombinant fusion proteins containing glutathione-S-transferase.

Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

An autoregulatory mechanism governing mucociliary transport is sensitive to mucus load

Analysis of cystic fibrosis-associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases

Antibodies against purified epithelial sodium channel protein from bovine renal papilla

Antisense oligodeoxynucleotide to the cystic fibrosis gene inhibits anion transport in normal cultured sweat duct cells

Assessing cell-specific effects of genetic variations using tRNA microarrays

Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing.

Association of cystic fibrosis genetic modifiers with congenital bilateral absence of the vas deferens

Bioelectric effects of quinine on polarized airway epithelial cells

Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene.

CFTR Folding Consortium: methods available for studies of CFTR folding and correction

CFTR modulator theratyping: Current status, gaps and future directions

Cell to Cell Contact Is Not Required for Bystander Cell Killing by Escherichia coli Purine Nucleoside Phosphorylase ⬇️

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

Characterization of defects in ion transport and tissue development in cystic fibrosis transmembrane conductance regulator (CFTR)-knockout rats

Chlorogenic Acid Activates CFTR-Mediated Cl- Secretion in Mice and Humans: Therapeutic Implications for Chronic Rhinosinusitis.

Chlorzoxazone or 1-EBIO increases Na(+) absorption across cystic fibrosis airway epithelial cells

Cigarette smoke condensate inhibits transepithelial chloride transport and ciliary beat frequency

Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model

Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy

Comparison of cystic fibrosis transmembrane conductance regulator (CFTR) and ciliary beat frequency activation by the CFTR Modulators Genistein, VRT-532, and UCCF-152 in primary sinonasal epithelial cultures

Comparison of vectorial ion transport in primary murine airway and human sinonasal air-liquid interface cultures, models for studies of cystic fibrosis, and other airway diseases.

Correction: Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung Disease

Correction: Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability

Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis

Cystic fibrosis

Cystic fibrosis precision therapeutics: Emerging considerations

Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain 1 (NBD-1) and CFTR truncated within NBD-1 target to the epithelial plasma membrane and increase anion permeability

Cystic fibrosis transmembrane conductance regulator activation by the solvent ethanol: implications for topical drug delivery.

Cystic fibrosis transmembrane conductance regulator modulation by the tobacco smoke toxin acrolein

Cystic fibrosis transmembrane conductance regulator mutations that disrupt nucleotide binding

Cystic fibrosis: a disorder of calcium-stimulated secretion and transepithelial sodium transport?

Development of an airway mucus defect in the cystic fibrosis rat.

Development of drug targeting based on recombinant expression of the chicken avidin gene

Diagnosis of genetic disease by primer-specified restriction map modification, with application to cystic fibrosis and retinitis pigmentosa

Effects of megestrol acetate on weight gain, body composition, and pulmonary function in patients with cystic fibrosis

Efficiency of plasmid delivery and expression after lipid-mediated gene transfer to human cells in vitro

Efficient intracellular processing of the endogenous cystic fibrosis transmembrane conductance regulator in epithelial cell lines

Elevation of hepatic sulphotransferase activities in mice with resistance to cystic fibrosis.

Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones

Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis

Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene

Exposure to cigarette smoke condensate reduces calcium activated chloride channel transport in primary sinonasal epithelial cultures

Extracellular zinc and ATP restore chloride secretion across cystic fibrosis airway epithelia by triggering calcium entry

Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report

Gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway

Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase

Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues

Hesperidin stimulates cystic fibrosis transmembrane conductance regulator-mediated chloride secretion and ciliary beat frequency in sinonasal epithelium

Heterozygosity for the F508del mutation in the cystic fibrosis transmembrane conductance regulator anion channel attenuates influenza severity

Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction

Identification of a membrane protein from T84 cells using antibodies made against a DIDS-binding peptide

Immunochemical localization of amiloride-sensitive sodium channels in sodium-transporting epithelia

In VivoGene Therapy of Cancer withE. coliPurine Nucleoside Phosphorylase ⬇️

In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics

Informed consent to participate in a research study -- gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway