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Lista de obras de Oliver Koch

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

artículo científico publicado en 2016

A benchmark driven guide to binding site comparison: An exhaustive evaluation using tailor-made data sets (ProSPECCTs)

artículo científico publicado en 2018

A novel interaction fingerprint derived from per atom score contributions: exhaustive evaluation of interaction fingerprint performance in docking based virtual screening.

artículo científico publicado en 2018

Advances in the Prediction of Turn Structures in Peptides and Proteins

artículo científico publicado en 2012

An automated method for consistent helix assignment using turn information.

artículo científico publicado en 2011

Binding site characterization - similarity, promiscuity, and druggability

scientific article published on 06 June 2019

CHIPMUNK: A virtual synthesizable small molecule library for medicinal chemistry exploitable for protein-protein interaction modulators.

artículo científico publicado en 2018

Complete, Programmable Decoding of Oxidized 5-Methylcytosine Nucleobases in DNA by Chemoselective Blockage of Universal Transcription-Activator-Like Effector Repeats.

artículo científico publicado en 2018

Cooperative effects in hydrogen-bonding of protein secondary structure elements: a systematic analysis of crystal data using Secbase.

artículo científico publicado en 2005

Design, synthesis and 3D-QSAR studies of novel 1,4-dihydropyridines as TGFβ/Smad inhibitors

artículo científico publicado en 2015

Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A.

artículo científico publicado en 2014

Identification of CLK1 Inhibitors by a Fragment-linking Based Virtual Screening

artículo científico publicado en 2016

Impact of Binding Site Comparisons on Medicinal Chemistry and Rational Molecular Design

artículo científico publicado en 2016

Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT.

artículo científico publicado en 2017

Interrogating Key Positions of Size-Reduced TALE Repeats Reveals a Programmable Sensor of 5-Carboxylcytosine

artículo científico publicado en 2016

One-Pot N2C/C2C/N2N Ligation To Trap Weak Protein-Protein Interactions

artículo científico publicado en 2016

Overcoming conservation in TALE-DNA interactions: a minimal repeat scaffold enables selective recognition of an oxidized 5-methylcytosine

article

Prediction of turn types in protein structure by machine-learning classifiers.

artículo científico publicado en 2009

PyGOLD: A python based API for docking based virtual screening workflow generation.

artículo científico publicado en 2017

Scaffold Hunter: a comprehensive visual analytics framework for drug discovery.

artículo científico publicado en 2017

Scaffold hunter: visual analysis of biological activity data.

artículo científico publicado en 2014

Secbase - secondary structure elements and ligand binding

Secbase: database module to retrieve secondary structure elements with ligand binding motifs.

artículo científico publicado en 2009

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated

scientific article published on 29 April 2019

Small-Molecule Inhibition of the UNC119-Cargo Interaction

artículo científico publicado en 2017

Spatiotemporal imaging of small GTPases activity in live cells

artículo científico publicado en 2016

Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.

artículo científico

Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein-Protein Interactions

artículo científico publicado en 2017

The Development of Target-Specific Machine Learning Models as Scoring Functions for Docking-Based Target Prediction

scientific article published on 18 March 2019

The N6-Position of Adenine Is a Blind Spot for TAL-Effectors That Enables Effective Binding of Methylated and Fluorophore-Labeled DNA.

artículo científico

Use of Secondary Structure Element Information in Drug Design: Polypharmacology and Conserved Motifs in Protein–Ligand Binding and Protein–Protein Interfaces

artículo científico publicado el 1 de abril de 2011

Visual Analysis of Biological Activity Data with Scaffold Hunter

artículo científico publicado en 2013

What Can We Learn from Bioactivity Data? Chemoinformatics Tools and Applications in Chemical Biology Research.

artículo científico publicado en 2016

ω-Imidazolyl- and ω-Tetrazolylalkylcarbamates as Inhibitors of Fatty Acid Amide Hydrolase: Biological Activity and in vitro Metabolic Stability.

artículo científico publicado en 2016