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Lista de obras de Jakub Hofman

Aldo-keto reductase 1C3 (AKR1C3): a missing piece of the puzzle in the dinaciclib interaction profile

scientific article published on 10 July 2018

Anthracycline resistance mediated by reductive metabolism in cancer cells: the role of aldo-keto reductase 1C3.

artículo científico publicado en 2014

Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes

artículo científico publicado en 2019

Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3

artículo científico publicado en 2019

Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters

scientific article published on 28 February 2019

Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment

artículo científico publicado en 2015

In vitro transfection mediated by dendrigraft poly(L-lysines): the effect of structure and molecule size.

artículo científico publicado en 2012

Inhibition of human anthracycline reductases by emodin - A possible remedy for anthracycline resistance.

artículo científico publicado en 2016

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance

scientific article published on 08 May 2019

Isoquinoline alkaloids as a novel type of AKR1C3 inhibitors

artículo científico publicado en 2014

Nitric oxide is involved in light-specific responses of tomato during germination under normal and osmotic stress conditions

artículo científico publicado en 2012

Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone.

artículo científico publicado en 2011

Olomoucine II, but not purvalanol A, is transported by breast cancer resistance protein (ABCG2) and P-glycoprotein (ABCB1)

artículo científico publicado en 2013

Pharmacokinetic interactions of breast cancer chemotherapeutics with human doxorubicin reductases.

artículo científico publicado en 2015

Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs).

artículo científico publicado en 2015

Purvalanol A, olomoucine II and roscovitine inhibit ABCB1 transporter and synergistically potentiate cytotoxic effects of daunorubicin in vitro

artículo científico publicado en 2013

Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro.

artículo científico publicado en 2018

Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment

scientific article published on 03 August 2018

Synchronized activity of organic cation transporter 3 (Oct3/Slc22a3) and multidrug and toxin extrusion 1 (Mate1/Slc47a1) transporter in transplacental passage of MPP+ in rat.

artículo científico publicado en 2012

Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: effect of drug efflux transporters and lipid solubility.

artículo científico publicado en 2009

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