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Lista de obras de Radek Pohl

13C GIAO DFT calculation as a tool for configuration prediction of N-O group in saturated heterocyclic N-oxides.

artículo científico publicado en 2012

2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove.

artículo científico publicado en 2016

4'-Alkoxy oligodeoxynucleotides: a novel class of RNA mimics

artículo científico publicado en 2011

6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study.

artículo científico publicado en 2016

A chiral dicationic [8]circulenoid: photochemical origin and facile thermal conversion into a helicene congener

artículo científico publicado en 2012

A facile and efficient synthesis of (Purin-6-yl)alanines

artículo científico publicado en 2004

A general approach to optically pure [5]-, [6]-, and [7]heterohelicenes

artículo científico publicado en 2012

Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA

artículo científico publicado en 2016

Additive Effects of Omega-3 Fatty Acids and Thiazolidinediones in Mice Fed a High-Fat Diet: Triacylglycerol/Fatty Acid Cycling in Adipose Tissue

scientific article published on 04 December 2020

Alkylsulfanylphenyl derivatives of cytosine and 7-deazaadenine nucleosides, nucleotides and nucleoside triphosphates: synthesis, polymerase incorporation to DNA and electrochemical study.

artículo científico publicado en 2011

Aminophenyl- and nitrophenyl-labeled nucleoside triphosphates: synthesis, enzymatic incorporation, and electrochemical detection

artículo científico publicado en 2008

An efficient method for the construction of functionalized DNA bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR

artículo científico publicado en 2007

Anthraquinone as a redox label for DNA: synthesis, enzymatic incorporation, and electrochemistry of anthraquinone-modified nucleosides, nucleotides, and DNA.

artículo científico publicado en 2011

Aqueous Heck cross-coupling preparation of acrylate-modified nucleotides and nucleoside triphosphates for polymerase synthesis of acrylate-labeled DNA.

artículo científico publicado en 2013

Asymmetric domino aza-Michael addition/[3 + 2] cycloaddition reactions as a versatile approach to α,β,γ-triamino acid derivatives

artículo científico publicado en 2014

Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions.

artículo científico publicado en 2014

Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking

artículo científico publicado en 2015

Base-modified DNA labeled by [Ru(bpy)(3)](2+) and [Os(bpy)(3)](2+) complexes: construction by polymerase incorporation of modified nucleoside triphosphates, electrochemical and luminescent properties, and applications.

artículo científico publicado en 2009

Benzofurazane as a new redox label for electrochemical detection of DNA: towards multipotential redox coding of DNA bases

artículo científico publicado en 2013

Bodipy-labeled nucleoside triphosphates for polymerase synthesis of fluorescent DNA.

artículo científico publicado en 2014

Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins

artículo científico publicado en 2016

Cleavage of functionalized DNA containing 5-modified pyrimidines by type II restriction endonucleases.

artículo científico publicado en 2011

Conjugate addition of diethyl 1-fluoro-1-phenylsulfonylmethanephosphonate to α,β-unsaturated compounds

scientific article published on 22 April 2013

Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides

artículo científico publicado en 2016

Correction to "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides"

artículo científico publicado en 2019

Cross-coupling reaction of saccharide-based alkenyl boronic acids with aryl halides: the synthesis of bergenin

artículo científico publicado en 2014

Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines

artículo científico publicado en 2006

Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA

artículo científico publicado en 2016

Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides

artículo científico publicado en 2005

Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics.

artículo científico publicado en 2017

Determination of the Nucleic Acid Adducts Structure at the Nucleoside/Nucleotide Level by NMR Spectroscopy

artículo científico publicado en 2015

Diethyl fluoronitromethylphosphonate: synthesis and application in nucleophilic fluoroalkyl additions

artículo científico publicado en 2014

Direct C-H arylation of purines: development of methodology and its use in regioselective synthesis of 2,6,8-trisubstituted purines

artículo científico publicado en 2006

Direct C-H borylation and C-H arylation of pyrrolo[2,3-d]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines

artículo científico publicado en 2009

Direct C-H sulfenylation of purines and deazapurines

artículo científico publicado en 2013

Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose

artículo científico publicado en 2015

Direct polymerase synthesis of reactive aldehyde-functionalized DNA and its conjugation and staining with hydrazines

scientific article published on 01 February 2010

Electrospray Ionization Mass Spectrometry Reveals an Unexpected Coupling Product in the Copper-Promoted Synthesis of Pyrazoles

article published in 2013

Emission color tuning in AlQ3 complexes with extended conjugated chromophores

artículo científico publicado en 2003

Erratum: Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature.

artículo científico publicado en 2016

Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity

artículo científico publicado en 2007

Facile and efficient synthesis of 6-(hydroxymethyl)purines

scientific article published on 01 September 2004

Ferrocenyl helquats: unusual chiral organometallic nonlinear optical chromophores.

artículo científico publicado en 2017

Ferrocenylethynyl derivatives of nucleoside triphosphates: synthesis, incorporation, electrochemistry, and bioanalytical applications

scientific article published on 01 January 2007

Flexible double-headed cytosine-linked 2'-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases.

artículo científico publicado en 2016

Functional helquats: helical cationic dyes with marked, switchable chiroptical properties in the visible region

artículo científico publicado en 2015

GFP-like fluorophores as DNA labels for studying DNA-protein interactions.

artículo científico publicado en 2012

Helquat Dyes: Helicene-like Push-Pull Systems with Large Second-Order Nonlinear Optical Responses.

artículo científico publicado en 2016

Helquats: a facile, modular, scalable route to novel helical dications

scientific article published on 01 January 2009

Highly Functionalized Cyclopentane Derivatives by Tandem Michael Addition/Radical Cyclization/Oxygenation Reactions.

artículo científico publicado en 2015

Highly functionalized and potent antiviral cyclopentane derivatives formed by a tandem process consisting of organometallic, transition-metal-catalyzed, and radical reaction steps.

artículo científico publicado en 2014

Insights into the Mechanism of Action of Bactericidal Lipophosphonoxins

artículo científico publicado en 2015

Intramolecular direct C-H arylation approach to fused purines. Synthesis of purino[8,9-f]phenanthridines and 5,6-dihydropurino[8,9-a]isoquinolines

artículo científico publicado en 2010

Limitations in the description of conformational preferences of C-disaccharides: The (1 → 3)-C-mannobiose case

artículo científico publicado en 2017

Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents

artículo científico publicado en 2017

Lipophosphonoxins: new modular molecular structures with significant antibacterial properties

artículo científico publicado en 2011

Lithium salts of [1,12-dialkyl-CB11Me10]- anions.

artículo científico publicado en 2010

Mekabu fucoidan: structural complexity and defensive effects against avian influenza A viruses

artículo científico publicado en 2014

Microwave-assisted alkylation of [CB11H12]- and related anions

scientific article published on 11 October 2010

Modular Stereoselective Synthesis of (1→2)-C-Glycosides based on the sp(2) -sp(3) Suzuki-Miyaura Reaction.

artículo científico publicado en 2015

Modular and practical synthesis of 6-substituted pyridin-3-yl C-nucleosides

artículo científico publicado en 2007

Modular synthesis of 5-substituted thiophen-2-yl C-2'-deoxyribonucleosides

artículo científico publicado en 2008

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor

artículo científico publicado en 2017

N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity

artículo científico publicado en 2014

N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides.

artículo científico publicado en 2015

N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.

artículo científico publicado en 2012

Observed and calculated 1H and 13C chemical shifts induced by the in situ oxidation of model sulfides to sulfoxides and sulfones.

artículo científico publicado en 2010

Oxidative catalysis using the stoichiometric oxidant as a reagent: an efficient strategy for single-electron-transfer-induced tandem anion-radical reactions.

artículo científico publicado en 2014

Oxidative radical cyclizations of diketopiperazines bearing an amidomalonate unit. Heterointermediate reaction sequences toward the asperparalines and stephacidins

artículo científico publicado en 2016

Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA.

artículo científico publicado en 2017

Phosphonoxins: rational design and discovery of a potent nucleotide anti-Giardia agent

scientific article published on 25 February 2007

Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides.

artículo científico publicado en 2010

Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins.

artículo científico publicado en 2015

Polymerase synthesis of DNAs bearing vinyl groups in the major groove and their cleavage by restriction endonucleases.

artículo científico publicado en 2014

Preparation of highly substituted 6-arylpurine ribonucleosides by Ni-catalyzed cyclotrimerization. Scope of the reaction

artículo científico publicado en 2006

Proton transfer in guanine-cytosine base pair analogues studied by NMR spectroscopy and PIMD simulations

scientific article published on 01 December 2018

Purines Bearing Phenanthroline or Bipyridine Ligands and Their RuII Complexes in Position 8 as Model Compounds for Electrochemical DNA Labeling – Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antivira

article

Pyrrolidine nucleotide analogs with a tunable conformation.

artículo científico publicado en 2014

Regioselective direct C-H arylations of protected uracils. Synthesis of 5- and 6-aryluracil bases

scientific article published on 26 May 2011

Resolving Electronic Transitions in Synthetic Fluorescent Protein Chromophores by Magnetic Circular Dichroism

artículo científico publicado en 2016

Sequential Oxidative and Reductive Radical Cyclization Approach toward Asperparaline C and Synthesis of Its 8-Oxo Analogue.

artículo científico publicado en 2017

Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions.

artículo científico publicado en 2016

Stepwise triple-click functionalization of synthetic peptides

scientific article published on 01 August 2018

Structural Features and Anti-coagulant Activity of the Sulphated Polysaccharide SPS-CF from a Green Alga Capsosiphon fulvescens.

artículo científico publicado en 2015

Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.).

artículo científico publicado en 2016

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides

artículo científico publicado en 2014

Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature

artículo científico publicado en 2016

Sugar modified pyrimido[4,5-]indole nucleosides: synthesis and antiviral activity

artículo científico publicado en 2017

Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosides

artículo científico publicado en 2012

Syntheses of N3-substituted thymine acyclic nucleoside phosphonates and a comparison of their inhibitory effect towards thymidine phosphorylase

artículo científico publicado en 2008

Syntheses of pyrimidine acyclic nucleoside phosphonates as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma

artículo científico publicado en 2007

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.

artículo científico publicado en 2017

Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides

scientific article published on 10 April 2020

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides

artículo científico publicado en 2018

Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides

artículo científico publicado en 2012

Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides.

artículo científico publicado en 2013

Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base

Synthesis and photophysical properties of 7-deaza-2'-deoxyadenosines bearing bipyridine ligands and their Ru(II)-complexes in position 7.

artículo científico publicado en 2008

Synthesis and photophysical properties of biaryl-substituted nucleos(t)ides. Polymerase synthesis of DNA probes bearing solvatochromic and pH-sensitive dual fluorescent and 19F NMR labels.

artículo científico publicado en 2011

Synthesis of 2'-deoxyadenosine nucleosides bearing bipyridine-type ligands and their Ru-complexes in position 8 through cross-coupling reactions.

artículo científico publicado en 2007

Synthesis of 6,8,9-tri- and 2,6,8,9-tetrasubstituted purines by a combination of the Suzuki cross-coupling, N-arylation, and direct C-H arylation reactions

artículo científico publicado en 2008

Synthesis of 8-bromo-, 8-methyl- and 8-phenyl-dATP and their polymerase incorporation into DNA.

artículo científico publicado en 2008

Synthesis of C-aryldeoxyribosides by [2 + 2 + 2]-cyclotrimerization catalyzed by Rh, Ni, Co, and Ru complexes

artículo científico publicado en 2006

Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism

artículo científico publicado en 2017

Synthesis of acetylene linked double-nucleobase nucleos(t)ide building blocks and polymerase construction of DNA containing cytosines in the major groove

artículo científico publicado en 2011

Synthesis of aldehyde-linked nucleotides and DNA and their bioconjugations with lysine and peptides through reductive amination.

artículo científico publicado en 2012

Synthesis of alkylcarbonate analogs of O-acetyl-ADP-ribose.

artículo científico publicado en 2013

Synthesis of bridged diketopiperazines by using the persistent radical effect and a formal synthesis of bicyclomycin

artículo científico publicado en 2015

Synthesis of enantiomerically pure (purin-6-yl)phenylalanines and their nucleosides, a novel type of purine-amino acid conjugates

artículo científico publicado en 2005

Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents

artículo científico publicado en 2010

Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA.

artículo científico publicado en 2010

Synthesis of nucleoside mono- and triphosphates bearing oligopyridine ligands, their incorporation into DNA and complexation with transition metals

scientific article published on 09 November 2011

Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations

Synthesis of oligoribonucleotides with phosphonate-modified linkages

artículo científico publicado en 2011

Synthesis of racemic and enantiomeric 3-pyrrolidinyl derivatives of purine and pyrimidine nucleobases.

artículo científico publicado en 2005

Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations

artículo científico publicado en 2008

Synthesis, Photophysical Properties and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides

scientific article published on 20 May 2020

Synthesis, conformational studies, and biological properties of phosphonomethoxyethyl derivatives of nucleobases with a locked conformation via a pyrrolidine ring.

artículo científico publicado en 2015

Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides

artículo científico publicado en 2007

Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides

artículo científico publicado en 2007

Tetrathiafulvalene-oligo(para-phenyleneethynylene) conjugates: formation of multiple mixed-valence complexes upon electrochemical oxidation.

artículo científico publicado en 2013

The 16 CB11(CH3)n(CD3)(12-n)• radicals with 5-fold substitution symmetry: spin density distribution in CB11Me12(•)

artículo científico publicado en 2012

The determination of sulfoxide configuration in five-membered rings using NMR spectroscopy and DFT calculations

The discovery of pyridinium 1,2,4-triazines with enhanced performance in bioconjugation reactions

scientific article published on 01 March 2017

The first direct C-H arylation of purine nucleosides

artículo científico publicado en 2007

The first synthesis and cytostatic activity of novel 6-(fluoromethyl)purine bases and nucleosides

artículo científico publicado en 2005

The observed and calculated 1H and 13C chemical shifts of tertiary amines and their N-oxides.

artículo científico publicado en 2011

The use of cobalt-mediated cycloisomerisation of ynedinitriles in the synthesis of pyridazinohelicenes.

artículo científico publicado en 2014

Total syntheses of all tri-oxygenated 16-phytoprostane classes via a common precursor constructed by oxidative cyclization and alkyl-alkyl coupling reactions as the key steps.

artículo científico publicado en 2017

Transient and switchable (triethylsilyl)ethynyl protection of DNA against cleavage by restriction endonucleases

artículo científico publicado en 2011

Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity

artículo científico publicado en 2006

Trifluoroacetophenone-Linked Nucleotides and DNA for Studying of DNA-Protein Interactions by 19F NMR Spectroscopy

artículo científico publicado en 2017

Tunable Chiral Second-Order Nonlinear Optical Chromophores Based on Helquat Dications.

artículo científico

Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity

artículo científico publicado en 2018

Vinylsulfonamide and acrylamide modification of DNA for cross-linking with proteins

artículo científico publicado en 2013

[2+2+2] Cycloisomerisation of Aromatic Cyanodiynes in the Synthesis of Pyridohelicenes and Their Analogues.

artículo científico publicado en 2016