Lista de obras - Alan Neil Schechter - Dominio Público Uruguay

A flow cytometric analysis of the inhibition of platelet reactivity due to nitrite reduction by deoxygenated erythrocytes.

artículo científico publicado en 2014

Acute erythropoietin cardioprotection is mediated by endothelial response.

artículo científico publicado en 2011

Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin ⬇️

artículo científico publicado el 23 de octubre de 2012

Binding of erythroid and non-erythroid nuclear proteins to the silencer of the human epsilon-globin-encoding gene

artículo científico publicado el 15 de enero de 1992

Comments on ‘Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate‐nitrite‐nitric oxide pathway’ ⬇️

artículo científico publicado el 1 de junio de 2013

Dietary nitrite and nitrate: a review of potential mechanisms of cardiovascular benefits.

artículo científico publicado en 2011

Effect of blood nitrite and nitrate levels on murine platelet function

artículo científico publicado en 2013

Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport

scientific article published on 01 August 2000

Effect of storage levels of nitric oxide derivatives in blood components.

artículo científico publicado en 2012

Effect of storage on levels of nitric oxide metabolites in platelet preparations

artículo científico publicado en 2012

Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery

artículo científico publicado en 2001

Effects of iron nitrosylation on sickle cell hemoglobin solubility

scientific article published on 22 July 2002

Effects of nitric oxide on red blood cell development and phenotype.

artículo científico publicado en 2008

Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control

artículo científico publicado en 2005

Erythrocytes are the major intravascular storage sites of nitrite in human blood.

artículo científico publicado en 2005

Erythropoietin and hypoxia increase erythropoietin receptor and nitric oxide levels in lung microvascular endothelial cells ⬇️

artículo científico publicado el 15 de febrero de 2011

Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.

artículo científico publicado en 2004

Filterability of mixtures of sickle and normal erythrocytes

scientific article published on 01 October 1995

Genetic diseases of hemoglobin: diagnostic methods for elucidating beta-thalassemia mutations.

artículo científico publicado en 2001

Globin gene expression in correlation with G protein-related genes during erythroid differentiation ⬇️

artículo científico publicado el 20 de febrero de 2013

Hemoglobin research and the origins of molecular medicine.

artículo científico publicado en 2008

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability

artículo científico publicado en 2007

Hydroxyurea and Hemin Affect Both the Transcriptional and Post‐Transcriptional Mechanisms of Some Globin Genes in Human Adult Erythroid Cellsa ⬇️

artículo científico publicado el 30 de junio de 1998

Hydroxyurea in sickle cell disease

scientific article published on 01 February 1996

Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity.

artículo científico publicado en 2007

Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

artículo científico publicado en 2003

Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells.

artículo científico publicado en 2006

Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation

artículo científico publicado en 2005

Identification and characterization of mechanistically distinct inducers of gamma-globin transcription

artículo científico publicado en 2003

In reply

In vivo reduction of cell-free methemoglobin to oxyhemoglobin results in vasoconstriction in canines

artículo científico publicado en 2013

Increased protein binding to a -530 mutation of the human beta-globin gene associated with decreased beta-globin synthesis

artículo científico publicado en 1991

Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life

artículo científico publicado en 2013

Increasing hemoglobin oxygen saturation levels in sickle trait donor whole blood prevents hemoglobin S polymerization and allows effective white blood cell reduction by filtration.

artículo científico publicado en 2004

Increasing oxygen tension improves filtration of sickle trait donor blood

artículo científico publicado en 2003

Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

artículo científico publicado en 2004

Inhibitory effect of nitrite on coagulation processes demonstrated by thrombelastography.

artículo científico publicado en 2014

Inorganic nitrate: a major player in the cardiovascular health benefits of vegetables? ⬇️

artículo científico publicado el 19 de abril de 2012

Isolation of antibodies specific to sickle hemoglobin by affinity chromatography using a synthetic peptide ⬇️

artículo científico publicado el 1 de diciembre de 1975

JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny

artículo científico publicado en 2012

Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins

scientific article published on 01 December 2000

Locus-control-region-coupled betaS Antilles- and alpha2-hemoglobin genes select for high alpha2-hemoglobin expression in adult transgenic mice ⬇️

artículo científico publicado el 1 de junio de 1994

Modifications of RNA processing modulate the expression of hemoglobin genes

artículo científico publicado en 1996

Multiple Regulatory Elements in the 5′-Flanking Sequence of the Human ε-Globin Gene

article

NIH support for basic and clinical research: biomedical researcher angst in 2006

artículo científico publicado en 2006

Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes.

artículo científico publicado en 2007

Nitric oxide's reactions with hemoglobin: a view through the SNO-storm ⬇️

artículo científico publicado el 1 de mayo de 2003

Nitric oxide-mediated heme oxidation and selective beta-globin nitrosation of hemoglobin from normal and sickle erythrocytes

scientific article published on 01 September 2000

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

artículo científico publicado en 2003

Overexpression of GATA-2 inhibits erythroid and promotes megakaryocyte differentiation.

artículo científico publicado en 2000

Oxidation of iron-nitrosyl-hemoglobin by dehydroascorbic acid releases nitric oxide to form nitrite in human erythrocytes.

artículo científico publicado en 2008

Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele

artículo científico publicado en 2001

Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation

artículo científico publicado en 2012

Preparation and properties of nickel hemoglobin.

artículo científico publicado en 1984

Proton Magnetic Resonance Studies at 220 MHz of the Histidine Residues of Staphylococcal Nuclease ⬇️

artículo científico publicado el 14 de noviembre de 1970

Randomization in clinical trials of titrated therapies: unintended consequences of using fixed treatment protocols.

artículo científico publicado en 2007

S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function.

artículo científico publicado en 2002

Sickle cell anemia--basic research reaches the clinic.

artículo científico publicado en 1995

Sickle cell rheology is determined by polymer fraction--not cell morphology

scientific article published on 01 January 1995

Stereospecific inhibitors of the gelation of sickle hemoglobin

artículo científico publicado en 1980

Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production.

artículo científico publicado en 2009

The active site of staphylococcal nuclease: paramagnetic relaxation of bound nucleotide inhibitor nuclei by lanthanide ions

scientific article published on July 1974

The concepts of crossreactivity and specificity in immunology

scientific article published on 01 August 1981

The crisis in clinical research: endangering the half-century National Institutes of Health Consensus

artículo científico publicado en 1998

The delta-globin RNA transcript level in beta-thalassemia carriers

artículo científico publicado en 1999

The emerging biology of the nitrite anion

artículo científico publicado en 2005

The immunochemical effects of metal substitution in the prosthetic group of hemoglobin

scientific article published on 01 December 1980

The measurement of blood and plasma nitrite by chemiluminescence: pitfalls and solutions.

artículo científico publicado en 2006

The reaction between nitrite and oxyhemoglobin: a mechanistic study

artículo científico publicado en 2008

The reaction of cell-free oxyhemoglobin with nitrite under physiologically relevant conditions: Implications for nitrite-based therapies.

artículo científico publicado en 2008

The role of nitrite in neurovascular coupling.

artículo científico publicado en 2011

The solubility of hemoglobins A and S reconstituted with various metalloporphyrins.

artículo científico publicado en 1982

To publish or not to publish?

artículo científico publicado en 2005

Lista de obras de Alan Neil Schechter

A flow cytometric analysis of the inhibition of platelet reactivity due to nitrite reduction by deoxygenated erythrocytes.

Acute erythropoietin cardioprotection is mediated by endothelial response.

Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin ⬇️

Binding of erythroid and non-erythroid nuclear proteins to the silencer of the human epsilon-globin-encoding gene

Comments on ‘Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate‐nitrite‐nitric oxide pathway’ ⬇️

Dietary nitrite and nitrate: a review of potential mechanisms of cardiovascular benefits.

Effect of blood nitrite and nitrate levels on murine platelet function

Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport

Effect of storage levels of nitric oxide derivatives in blood components.

Effect of storage on levels of nitric oxide metabolites in platelet preparations

Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery

Effects of iron nitrosylation on sickle cell hemoglobin solubility

Effects of nitric oxide on red blood cell development and phenotype.

Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control

Erythrocytes are the major intravascular storage sites of nitrite in human blood.

Erythropoietin and hypoxia increase erythropoietin receptor and nitric oxide levels in lung microvascular endothelial cells ⬇️

Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.

Filterability of mixtures of sickle and normal erythrocytes

Genetic diseases of hemoglobin: diagnostic methods for elucidating beta-thalassemia mutations.

Globin gene expression in correlation with G protein-related genes during erythroid differentiation ⬇️

Hemoglobin research and the origins of molecular medicine.

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability

Hydroxyurea and Hemin Affect Both the Transcriptional and Post‐Transcriptional Mechanisms of Some Globin Genes in Human Adult Erythroid Cellsa ⬇️

Hydroxyurea in sickle cell disease

Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity.

Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells.

Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation

Identification and characterization of mechanistically distinct inducers of gamma-globin transcription

In reply

In vivo reduction of cell-free methemoglobin to oxyhemoglobin results in vasoconstriction in canines

Increased protein binding to a -530 mutation of the human beta-globin gene associated with decreased beta-globin synthesis

Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life

Increasing hemoglobin oxygen saturation levels in sickle trait donor whole blood prevents hemoglobin S polymerization and allows effective white blood cell reduction by filtration.

Increasing oxygen tension improves filtration of sickle trait donor blood

Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

Inhibitory effect of nitrite on coagulation processes demonstrated by thrombelastography.

Inorganic nitrate: a major player in the cardiovascular health benefits of vegetables? ⬇️

Isolation of antibodies specific to sickle hemoglobin by affinity chromatography using a synthetic peptide ⬇️

JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny

Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins

Locus-control-region-coupled betaS Antilles- and alpha2-hemoglobin genes select for high alpha2-hemoglobin expression in adult transgenic mice ⬇️

Modifications of RNA processing modulate the expression of hemoglobin genes

Multiple Regulatory Elements in the 5′-Flanking Sequence of the Human ε-Globin Gene

NIH support for basic and clinical research: biomedical researcher angst in 2006

Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes.

Nitric oxide's reactions with hemoglobin: a view through the SNO-storm ⬇️

Nitric oxide-mediated heme oxidation and selective beta-globin nitrosation of hemoglobin from normal and sickle erythrocytes

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

Overexpression of GATA-2 inhibits erythroid and promotes megakaryocyte differentiation.

Oxidation of iron-nitrosyl-hemoglobin by dehydroascorbic acid releases nitric oxide to form nitrite in human erythrocytes.

Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele

Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation

Preparation and properties of nickel hemoglobin.

Proton Magnetic Resonance Studies at 220 MHz of the Histidine Residues of Staphylococcal Nuclease ⬇️

Randomization in clinical trials of titrated therapies: unintended consequences of using fixed treatment protocols.

S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function.

Sickle cell anemia--basic research reaches the clinic.

Sickle cell rheology is determined by polymer fraction--not cell morphology

Stereospecific inhibitors of the gelation of sickle hemoglobin

Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production.

The active site of staphylococcal nuclease: paramagnetic relaxation of bound nucleotide inhibitor nuclei by lanthanide ions

The concepts of crossreactivity and specificity in immunology

The crisis in clinical research: endangering the half-century National Institutes of Health Consensus

The delta-globin RNA transcript level in beta-thalassemia carriers

The emerging biology of the nitrite anion

The immunochemical effects of metal substitution in the prosthetic group of hemoglobin

The measurement of blood and plasma nitrite by chemiluminescence: pitfalls and solutions.

The reaction between nitrite and oxyhemoglobin: a mechanistic study

The reaction of cell-free oxyhemoglobin with nitrite under physiologically relevant conditions: Implications for nitrite-based therapies.

The role of nitrite in neurovascular coupling.

The solubility of hemoglobins A and S reconstituted with various metalloporphyrins.

To publish or not to publish?