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Lista de obras de Geert Molenberghs

A Bayesian, generalized frailty model for comet assays

artículo científico publicado en 2013

A Flexible Method to Measure Synchrony in Neuronal Firing

A bivariate pseudolikelihood for incomplete longitudinal binary data with nonignorable nonmonotone missingness

artículo científico publicado en 2010

A closed-form estimator for meta-analysis and surrogate markers evaluation

artículo científico publicado en 2018

A clustering algorithm for multivariate longitudinal data

artículo científico publicado en 2015

A comparison of doubly hierarchical discriminant analyses for multiple class longitudinal data from EEG experiments

artículo científico publicado en 2008

A generalized Poisson-gamma model for spatially overdispersed data

artículo científico publicado en 2011

A hierarchical Binomial-Poisson model for the analysis of a crossover design for correlated binary data when the number of trials is dose-dependent

artículo científico publicado en 2005

A hierarchical modeling approach for risk assessment in developmental toxicity studies

article

A high-dimensional joint model for longitudinal outcomes of different nature

artículo científico publicado en 2008

A joint model for hierarchical continuous and zero-inflated overdispersed count data

A joint model for longitudinal continuous and time-to-event outcomes with direct marginal interpretation

artículo científico publicado en 2013

A latent pharmacokinetic time profile to model dose-response survival data

artículo científico publicado en 2010

A latent-class mixture model for incomplete longitudinal Gaussian data

artículo científico publicado en 2007

A local influence approach applied to binary data from a psychiatric study

artículo científico publicado en 2003

A local influence approach to sensitivity analysis of incomplete longitudinal ordinal data

A local influence sensitivity analysis for incomplete longitudinal depression data

artículo científico publicado en 2006

A maximum entropy approach for the evaluation of surrogate endpoints based on causal inference

artículo científico publicado en 2018

A modeling approach to the analysis of nerve regenerative experiments

artículo científico publicado en 2006

A multilevel model for hierarchical, repeated, and overdispersed time-to-event outcomes and its estimation strategies

artículo científico publicado en 2013

A multiple-imputation-based approach to sensitivity analyses and effectiveness assessments in longitudinal clinical trials

artículo científico publicado en 2014

A new modeling approach for quantifying expert opinion in the drug discovery process

artículo científico publicado en 2015

A nonparametric approach to weighted estimating equations for regression analysis with missing covariates

article

A perspective on surrogate endpoints in controlled clinical trials

artículo científico publicado en 2004

A portfolio-based approach to optimize proof-of-concept clinical trials

artículo científico publicado en 2012

A reflection on the causal interpretation of individual-level surrogacy

artículo científico publicado en 2019

A reflection on the possibility of finding a good surrogate

artículo científico publicado en 2019

A sensitivity analysis for shared-parameter models for incomplete longitudinal outcomes

artículo científico publicado en 2010

A structured approach to choosing estimands and estimators in longitudinal clinical trials ⬇️

artículo científico publicado el 10 de septiembre de 2012

A unified framework for the evaluation of surrogate endpoints in mental-health clinical trials

artículo científico publicado en 2009

A unifying approach for surrogate marker validation based on Prentice's criteria

artículo científico publicado en 2006

A weighted combination of pseudo-likelihood estimators for longitudinal binary data subject to non-ignorable non-monotone missingness

artículo científico publicado en 2010

A zero-inflated overdispersed hierarchical Poisson model

Accounting for variability in individual hierarchical clinical trial data

artículo científico publicado en 2008

Adaptive change-point mixed models applied to data on outpatient tetracycline use in Europe

Alternative methods to evaluate trial level surrogacy

artículo científico publicado en 2008

An efficient algorithm to assess multivariate surrogate endpoints in a causal inference framework

artículo científico publicado en 2022

An equivalence test for comparing DNA sequences

An evaluation of the trimmed mean approach in clinical trials with dropout

artículo científico publicado en 2018

An extended random-effects approach to modeling repeated, overdispersed count data

artículo científico publicado en 2007

An information-theoretic approach for the evaluation of surrogate endpoints based on causal inference

artículo científico publicado en 2016

An information-theoretic approach to surrogate-marker evaluation with failure time endpoints ⬇️

artículo científico publicado el 28 de septiembre de 2010

An information‐theoretic approach for the assessment of a continuous outcome as a surrogate for a binary true endpoint based on causal inference: Application to vaccine evaluation

artículo científico publicado en 2024

Analysing the composition of outpatient antibiotic use: a tutorial on compositional data analysis

artículo científico publicado en 2011

Analysis of an incomplete binary outcome derived from frequently recorded longitudinal continuous data: application to daily pain evaluation ⬇️

artículo científico publicado el 23 de febrero de 2012

Analysis of non-ignorable missing and left-censored longitudinal data using a weighted random effects tobit model

artículo científico publicado en 2011

Analyzing incomplete longitudinal clinical trial data

artículo científico publicado en 2004

Application of mixed-effects models to study the country-specific outpatient antibiotic use in Europe: a tutorial on longitudinal data analysis

artículo científico publicado en 2011

Application of penalized splines in analyzing neuronal data

artículo científico publicado en 2009

Application of semiparametric mixed models and simultaneous confidence bands in a cardiovascular safety experiment with longitudinal data

artículo científico publicado en 2008

Applying concepts of generalizability theory on clinical trial data to investigate sources of variation and their impact on reliability

artículo científico publicado en 2005

Applying linear mixed models to estimate reliability in clinical trial data with repeated measurements

artículo científico publicado en 2004

Assessing and interpreting treatment effects in longitudinal clinical trials with missing data ⬇️

artículo científico publicado el 15 de abril de 2003

Assessment of type I error rate associated with dose-group switching in a longitudinal Alzheimer trial

artículo científico publicado en 2014

Attitudes and stigma in relation to help-seeking intentions for psychological problems in low and high suicide rate regions ⬇️

artículo científico publicado el 30 de julio de 2013

Bayesian testing for trend in a power model for clustered binary data

artículo científico publicado en 2004

Behavioral testing of antidepressant compounds: an analysis of crossover design for correlated binary data

artículo científico publicado en 2005

Biometry, biometrics, biostatistics, bioinformatics,..., bio-X.

artículo científico publicado en 2005

Characteristics of heart, arteries, and veins in low and high cardiac output preeclampsia ⬇️

artículo científico publicado el 20 de abril de 2013

Choice of units of analysis and modeling strategies in multilevel hierarchical models

Choosing estimands in clinical trials with missing data

artículo científico publicado en 2016

Cluster analysis for repeated data with dropout: Sensitivity analysis using a distal event.

artículo científico publicado en 2018

Clustering multiply imputed multivariate high-dimensional longitudinal profiles

artículo científico publicado en 2017

Combined models for data from in vitro-in vivo correlation experiments

artículo científico publicado en 2008

Comment on "Sexual maturation in relation to polychlorinated aromatic hydrocarbons: Sharpe and Skakkebaek's hypothesis revisited"

artículo científico publicado en 2003

Comparison of methods for the selection of genomic biomarkers

artículo científico publicado en 2013

Comparison of risks of cardiovascular events in the elderly using standard survival analysis and multiple-events and recurrent-events methods

artículo científico publicado en 2015

Comparison of the guaranteed analysis with the measured nutrient composition of commercial pet foods

artículo científico publicado en 2009

Conditional mixed models with crossed random effects

artículo científico publicado en 2007

Conflicts of interest and independent data analysis in industry-funded studies

artículo científico publicado en 2005

Correction for model selection bias using a modified model averaging approach for supervised learning methods applied to EEG experiments

artículo científico publicado en 2010

Cross nearest-spike interval based method to measure synchrony dynamics

artículo científico publicado en 2014

Detecting influential observations in a model-based cluster analysis

artículo científico publicado en 2016

Direct likelihood analysis versus simple forms of imputation for missing data in randomized clinical trials

artículo científico publicado en 2005

Diurnal and position-induced variability of impedance cardiography measurements in healthy subjects

artículo científico publicado en 2010

Do inter-hospital comparisons of in-hospital, acute myocardial infarction case-fatality rates serve the purpose of fostering quality improvement? An evaluative study

artículo científico publicado en 2010

Doubly robust and multiple-imputation-based generalized estimating equations

artículo científico publicado en 2011

Dynamic manganese-enhanced MRI signal intensity processing based on nonlinear mixed modeling to study changes in neuronal activity

Dynamic predictions with time-dependent covariates in survival analysis using joint modeling and landmarking

artículo científico

Editorial "Joint modeling of longitudinal and time-to-event data and beyond".

artículo científico publicado en 2017

Efficacy of daily intake of Lactobacillus casei Shirota on respiratory symptoms and influenza vaccination immune response: a randomized, double-blind, placebo-controlled trial in healthy elderly nursing home residents

article

Empirical Bayes Estimates for Correlated Hierarchical Data with Overdispersion

artículo científico publicado en 2014

Establishing normative data for multi-trial memory tests: the multivariate regression-based approach

artículo científico publicado en 2017

Establishing normative data for repeated cognitive assessment: a comparison of different statistical methods

artículo científico publicado en 2013

Estimating reliability and generalizability from hierarchical biomedical data

artículo científico publicado en 2007

Estimating the causal effect of compliance on binary outcome in randomized controlled trials ⬇️

artículo científico publicado el 15 de febrero de 1998

Estimation of the Force of Infection from Current Status Data Using Generalized Linear Mixed Models

article published in 2007

European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997-2009).

artículo científico publicado en 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient cephalosporin use in Europe (1997-2009).

artículo científico publicado en 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe (1997-2009).

artículo científico publicado en 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient penicillin use in Europe (1997-2009).

artículo científico publicado en 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient quinolone use in Europe (1997-2009).

artículo científico publicado en 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient use of tetracyclines, sulphonamides and trimethoprim, and other antibacterials in Europe (1997-2009).

artículo científico publicado en 2011

Evaluation of biomarkers for pharmacological activity

artículo científico publicado en 2009

Evaluation of chromogenic media for detection of methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2010

Evaluation of molecular assays for rapid detection of methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2010

Evaluation of six months sputum culture conversion as a surrogate endpoint in a multidrug resistant-tuberculosis trial

scientific article published in PLoS ONE

Exploring the relationship between the causal-inference and meta-analytic paradigms for the evaluation of surrogate endpoints

artículo científico publicado en 2015

Fast and highly efficient pseudo-likelihood methodology for large and complex ordinal data

artículo científico publicado en 2015

Fast precision estimation in high-dimensional multivariate joint models

artículo científico publicado en 2017

Flexible modelling of neuron firing rates across different experimental conditions: an application to neural activity in the prefrontal cortex during a discrimination task

Functionally Unidimensional Item Response Models for Multivariate Binary Data

artículo científico publicado en 2013

Generalizability in nongaussian longitudinal clinical trial data based on generalized linear mixed models

artículo científico publicado en 2008

Generalized pairwise comparison methods to analyze (non)prioritized composite endpoints

scientific article published on 28 October 2019

Generalized reliability estimation using repeated measurements

artículo científico publicado en 2006

Generalized shared-parameter models and missingness at random

Graphical exploration of gene expression data: a comparative study of three multivariate methods

artículo científico publicado en 2003

Handling of missing data in long-term clinical trials: a case study

artículo científico publicado en 2012

Help-seeking, stigma and attitudes of people with and without a suicidal past. A comparison between a low and a high suicide rate country

artículo científico publicado en 2015

Heterogeneity of symptom pattern, psychosocial factors, and pathophysiological mechanisms in severe functional dyspepsia

artículo científico publicado en 2003

High dimensional surrogacy: computational aspects of an upscaled analysis

artículo científico publicado en 2019

Ignoring overdispersion in hierarchical loglinear models: Possible problems and solutions

artículo científico publicado en 2012

Impact of selection bias on the evaluation of clusters of chemical compounds in the drug discovery process

artículo científico publicado en 2014

Impedance cardiography in uncomplicated pregnancy and pre-eclampsia: A reliability study ⬇️

artículo científico publicado el 1 de octubre de 2012

Including information on the therapeutic window in bioequivalence acceptance

artículo científico publicado en 2008

Incomplete hierarchical data

artículo científico publicado en 2007

Inferential Implications of Over-Parametrization: A Case Study in Incomplete Categorical Data

Information-theory based surrogate marker evaluation from several randomized clinical trials with continuous true and binary surrogate endpoints

artículo científico publicado en 2007

Introducing the Multivariate Dale Model in Population-Based Genetic Association Studies

Investigating association between behavior, corticosterone, heart rate, and blood pressure in rats using surrogate marker evaluation methodology

artículo científico publicado en 2009

Investigating the criterion validity of psychiatric symptom scales using surrogate marker validation methodology

artículo científico publicado en 2002

Joint modeling of hierarchically clustered and overdispersed non-gaussian continuous outcomes for comet assay data

artículo científico publicado en 2012

Joint modeling of multiple ordinal adherence outcomes via generalized estimating equations with flexible correlation structure.

artículo científico publicado en 2017

Kernel weighted influence measures

article published in 2005

Last observation carried forward: a crystal ball?

artículo científico publicado en 2009

Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

artículo científico publicado en 2018

Likelihood Ratio, Score, and Wald Tests in a Constrained Parameter Space

article by Geert Molenberghs & Geert Verbeke published February 2007 in The American Statistician

Marginalized multilevel hurdle and zero-inflated models for overdispersed and correlated count data with excess zeros

artículo científico publicado en 2014

Maternal and peer attachment, identity formation, and non-suicidal self-injury: a longitudinal mediation study

Maternal venous hemodynamics in gestational hypertension and preeclampsia

artículo científico publicado en 2014

Measurement agreement of the self-administered questionnaire of the Belgian Health Interview Survey: Paper-and-pencil versus web-based mode.

artículo científico publicado en 2018

Measuring trends of outpatient antibiotic use in Europe: jointly modelling longitudinal data in defined daily doses and packages

artículo científico publicado en 2014

Microbial Performance of Food Safety Control and Assurance Activities in a Fresh Produce Processing Sector Measured Using a Microbial Assessment Scheme and Statistical Modeling

artículo científico publicado en 2017

Missing data methods in longitudinal studies: a review

artículo científico publicado en 2009

Mixed models approaches for joint modeling of different types of responses

artículo científico publicado en 2015

Model-based estimates of long-term persistence of induced HPV antibodies: a flexible subject-specific approach

artículo científico publicado en 2013

Modeling actor and partner effects in dyadic data when outcomes are categorical

artículo científico publicado en 2013

Modeling anti-KLH ELISA data using two-stage and mixed effects models in support of immunotoxicological studies

artículo científico publicado en 2005

Modeling combined continuous and ordinal outcomes in a clustered setting

Modelling associations between time-to-event responses in pilot cancer clinical trials using a Plackett-Dale model

artículo científico publicado en 2004

Modelling forces of infection by using monotone local polynomials

Multicollinearity in prognostic factor analyses using the EORTC QLQ-C30: identification and impact on model selection

artículo científico publicado en 2002

Multinomial additive hazard model to assess the disability burden using cross-sectional data

artículo científico publicado en 2017

Multiple-imputation-based residuals and diagnostic plots for joint models of longitudinal and survival outcomes

artículo científico publicado en 2009

Non-linear Models for Longitudinal Data

artículo científico publicado en 2009

Norman Breslow's leadership for the international biometric society

artículo científico publicado en 2007

Occurrence of both bladder and prostate cancer in five cancer registries in Belgium, The Netherlands and the United Kingdom

artículo científico publicado en 2007

On random sample size, ignorability, ancillarity, completeness, separability, and degeneracy: sequential trials, random sample sizes, and missing data

artículo científico publicado en 2012

On the relationship between association and surrogacy when both the surrogate and true endpoint are binary outcomes

artículo científico publicado en 2020

On the relationship between the causal-inference and meta-analytic paradigms for the validation of surrogate endpoints

artículo científico publicado en 2014

On using multiple imputation for exploratory factor analysis of incomplete data

artículo científico publicado en 2018

PP070. Maternal cardiovascular profiling in the first trimester ofpregnancies complicated with gestation induced hypertension or fetal growth restriction

artículo científico publicado en 2013

PP078. The influence of maternal position on gestational hemodynamics

artículo científico publicado en 2013

Parametric overdispersed frailty models for current status data

artículo científico publicado en 2017

Perinatal outcome of 12,021 singleton and 3108 twin births after non-IVF-assisted reproduction: a cohort study

artículo científico publicado en 2005

Perinatal outcome of ICSI pregnancies compared with a matched group of natural conception pregnancies in Flanders (Belgium): a cohort study

artículo científico publicado en 2005

Predicting pregnancy rate and live birth rate in the IVF clinic by analysing patient profiles.

artículo científico publicado en 2015

Prediction of survival and opportunistic infections in HIV-infected patients: a comparison of imputation methods of incomplete CD4 counts

artículo científico publicado en 2002

Predictors of oligoamenorrhea at 1-year follow-up in premenopausal women using a levonorgestrel-releasing intrauterine system

artículo científico publicado en 2007

Premature discontinuation during the UPLIFT study

artículo científico publicado en 2011

Properties of Estimators in Exponential Family Settings with Observation-based Stopping Rules

artículo científico publicado en 2016

Pseudo-likelihood estimation for a marginal multivariate survival model

artículo científico publicado en 2004

Random effects models for estimation of the probability and time to progression of a continuous biomarker

scientific article published on 15 July 2019

Reliability measures in item response theory: manifest versus latent correlation functions

artículo científico publicado en 2014

Remote Monitoring of Hypertension Diseases in Pregnancy: A Pilot Study

artículo científico publicado en 2017

Response to comments on "Marginalized multilevel hurdle and zero-inflated models for overdispersed and correlated count data with excess zeros".

artículo científico publicado en 2018

Sample substitution can be an acceptable data-collection strategy: the case of the Belgian Health Interview Survey

artículo científico publicado en 2017

Screening for inter-hospital differences in cesarean section rates in low-risk deliveries using administrative data: an initiative to improve the quality of care

artículo científico publicado en 2008

Secondary stroke prevention: misguided by guidelines? ⬇️

artículo científico publicado el 1 de agosto de 2012

Selection models and pattern-mixture models to analyse longitudinal quality of life data subject to drop-out

artículo científico publicado en 2002

Semi-parametric Bayesian analysis of binary responses with a continuous covariate subject to non-random missingness

article

Sensitivity analysis for incomplete continuous data

article published in 2010

Sensitivity analysis for pattern mixture models

artículo científico publicado en 2004

Serial correlation structures in latent linear mixed models for analysis of multivariate longitudinal ordinal responses

artículo científico publicado en 2020

Simplified hierarchical linear models for the evaluation of surrogate endpoints

Spatial analysis of breast and cervical cancer incidence in small geographical areas in Cuba, 1999-2003.

artículo científico publicado en 2009

Statistical Validation of Surrogate Endpoints: Problems and Proposals

Statistical Validation of Surrogate Markers in Clinical Trials

Statistical challenges in the evaluation of surrogate endpoints in randomized trials

artículo científico publicado en 2002

Statistical evaluation of surrogate endpoints with examples from cancer clinical trials

artículo científico publicado en 2015

Statistical models for analyzing repeated quality measurements of horticultural products. Model evaluations and practical example

artículo científico publicado en 2003

Statistical software for calculating properly weighted estimates from Health Interview Survey Data

artículo científico publicado en 2003

Stigma, Attitudes, and Help-Seeking Intentions for Psychological Problems in Relation to Regional Suicide Rates

artículo científico publicado en 2015

Surrogate end points: hopes and perils

artículo científico publicado en 2008

Teaching statistical thinking to life scientists a case-based approach

artículo científico publicado en 2006

Testing for misspecification in generalized linear mixed models

artículo científico publicado en 2010

Tests for Homogeneity of the Risk Difference when Data are Sparse

artículo científico publicado el 1 de marzo de 1998

The Effect of Transborder Mobility on COVID-19 Incidences in Belgium

artículo científico publicado en 2022

The Effective Sample Size and an Alternative Small-Sample Degrees-of-Freedom Method

The Relation Between Aggression and the Living Group Climate in a Forensic Treatment Unit for Adolescents: A Pilot Study

artículo científico publicado en 2017

The Shape of Correlation Matrices

The analysis of multivariate longitudinal data: A review

artículo científico publicado en 2017

The analysis of multivariate longitudinal data: a review

artículo científico publicado en 2012

The effect of correlation structure on treatment contrasts estimated from incomplete clinical trial data with likelihood-based repeated measures compared with last observation carried forward ANOVA.

artículo científico publicado en 2004

The gradient function as an exploratory goodness-of-fit assessment of the random-effects distribution in mixed models

artículo científico publicado en 2013

The impact of missing data on clinical trials: a re-analysis of a placebo controlled trial of Hypericum perforatum (St Johns wort) and sertraline in major depressive disorder

artículo científico publicado en 2014

The meta-analytic framework for the evaluation of surrogate endpoints in clinical trials

The nature of sensitivity in monotone missing not at random models

article

The prevention and treatment of missing data in clinical trials

artículo científico publicado en 2012

The use of health care services and psychotropic medication in a community sample of 9-year-old schoolchildren with ADHD.

artículo científico publicado en 2007

The use of score tests for inference on variance components

artículo científico publicado en 2003

The validation of surrogate end points by using data from randomized clinical trials: a case-study in advanced colorectal cancer

Thyroid Cancer Incidence around the Belgian Nuclear Sites, 2000-2014.

artículo científico publicado en 2017

Thyroid cancer incidence near nuclear sites in Belgium: An ecological study at small geographical level

scientific article published on 10 December 2019

Titrating Theileria parva: single stocks against combination of stocks

artículo científico publicado en 2007

To adjust or not to adjust for baseline when analyzing repeated binary responses? The case of complete data when treatment comparison at study end is of interest

artículo científico publicado en 2015

Type I and Type II error under random-effects misspecification in generalized linear mixed models

artículo científico publicado en 2007

Type I error rates from likelihood-based repeated measures analyses of incomplete longitudinal data

article

Type-specific orthostatic hemodynamic response of hypertensive diseases in pregnancy

artículo científico publicado en 2015

Use of fractional polynomials for dose-response modelling and quantitative risk assessment in developmental toxicity studies

article

Using longitudinal data from a clinical trial in depression to assess the reliability of its outcome scales

artículo científico publicado en 2008

Validation of Surrogate Endpoints in Multiple Randomized Clinical Trials with Discrete Outcomes

Validation of a longitudinally measured surrogate marker for a time-to-event endpoint

Validation of surrogate end points in multiple randomized clinical trials with failure time end points

Validation of surrogate markers in multiple randomized clinical trials with repeated measurements: canonical correlation approach

artículo científico publicado en 2004

Venous Pulse Transit Time in Normal Pregnancy and Preeclampsia ⬇️

artículo científico publicado el 28 de febrero de 2012

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